Determination of xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) and rat and its application in bioaccumulation assessment

Environmental Science and Technology

Volumn 41, Issue 9, 2007, Pages 3269-3276

  Han, Xing ^a   Nabb, Diane L ^a   Mingoia, Robert T ^a   Yang, Ching Hui ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CONCENTRATION (PROCESS); FISH; RATE CONSTANTS; RATS; SUBSTRATES;

BIOACCUMULATION ASSESSMENT; HEPATOCYTES; KINETIC MODEL;

LIVING SYSTEMS STUDIES;

4 NONYLPHENOL; ATRAZINE; BENZO[A]PYRENE; BENZOPHENONE DERIVATIVE; MOLINATE; PHENOL DERIVATIVE; TRIFLURALIN; XENOBIOTIC AGENT;

CELLS; CONCENTRATION (PROCESS); FISH; LIVING SYSTEMS STUDIES; RATE CONSTANTS; RATS; SUBSTRATES;

ASSESSMENT METHOD; ATRAZINE; BIOACCUMULATION; BIOLOGICAL UPTAKE; BIOTRANSFORMATION; RODENT; SALMONID; XENOBIOTICS;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; BIOTRANSFORMATION; CELL ISOLATION; CONTROLLED STUDY; KINETICS; LIVER CELL; LIVER CLEARANCE; MALE; NONHUMAN; RAINBOW TROUT; RAT; XENOBIOTIC METABOLISM;

ANIMALS; ATRAZINE; AZEPINES; BENZO(A)PYRENE; BENZOPHENONES; BIOTRANSFORMATION; CELLS, CULTURED; HEPATOCYTES; MALE; ONCORHYNCHUS MYKISS; PHENOLS; RATS; RATS, INBRED STRAINS; THIOCARBAMATES; TRIFLURALIN; XENOBIOTICS;

ONCORHYNCHUS MYKISS; RATTUS; SALMONIDAE;

EID: 34248207703     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es0626279     Document Type: Article

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