-
1
-
-
0034727066
-
Multiple sclerosis
-
Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG (2000) Multiple sclerosis. N Engl J Med 343, 938-52.
-
(2000)
N Engl J Med
, vol.343
, pp. 938-952
-
-
Noseworthy, J.H.1
Lucchinetti, C.2
Rodriguez, M.3
Weinshenker, B.G.4
-
2
-
-
0029913882
-
Defining the clinical course of multiple sclerosis: Results of an international survey
-
National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis
-
Lublin FD, Reingold SC (1996) Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 46, 907-11.
-
(1996)
Neurology
, vol.46
, pp. 907-911
-
-
Lublin, F.D.1
Reingold, S.C.2
-
3
-
-
0037465364
-
MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals
-
Cotton F, Weiner HL, Jolesz FA, Guttmann CR (2003) MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals. Neurology 60, 640-6. (Pubitemid 36246083)
-
(2003)
Neurology
, vol.60
, Issue.4
, pp. 640-646
-
-
Cotton, F.1
Weiner, H.L.2
Jolesz, F.A.3
Guttmann, C.R.G.4
-
4
-
-
0032882173
-
Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis
-
DOI 10.1002/1531-8249(199909)46:3<296::AID-ANA4
-
Coles AJ, Wing MG, Molyneux P, Paolillo A, Davie CM, et al. (1999) Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis. Ann Neurol 46, 296-304. (Pubitemid 29416266)
-
(1999)
Annals of Neurology
, vol.46
, Issue.3
, pp. 296-304
-
-
Coles, A.J.1
Wing, M.G.2
Molyneux, P.3
Paolillo, A.4
Davie, C.M.5
Hale, G.6
Miller, D.7
Waldmann, H.8
Compston, A.9
-
5
-
-
33646201174
-
Magnetic resonance imaging measures of brain atrophy in multiple sclerosis
-
Anderson VM, Fox NC, Miller DH (2006) Magnetic resonance imaging measures of brain atrophy in multiple sclerosis. J Magn Reson Imaging 23, 605-18.
-
(2006)
J Magn Reson Imaging
, vol.23
, pp. 605-618
-
-
Anderson, V.M.1
Fox, N.C.2
Miller, D.H.3
-
6
-
-
34248643430
-
Neuroimaging in multiple sclerosis
-
Zivadinov R, Cox JL (2007) Neuroimaging in multiple sclerosis. Int Rev Neurobiol 79, 449-74.
-
(2007)
Int Rev Neurobiol
, vol.79
, pp. 449-474
-
-
Zivadinov, R.1
Cox, J.L.2
-
7
-
-
34249734136
-
New concepts on progressive multiple sclerosis
-
Lassmann H (2007) New concepts on progressive multiple sclerosis. Curr Neurol Neurosci Rep 7, 239-44.
-
(2007)
Curr Neurol Neurosci Rep
, vol.7
, pp. 239-244
-
-
Lassmann, H.1
-
8
-
-
73449124392
-
Progressive multiple sclerosis
-
Bradl M, Lassmann H (2009) Progressive multiple sclerosis. Semin Immunopathol 31, 455-65.
-
(2009)
Semin Immunopathol
, vol.31
, pp. 455-465
-
-
Bradl, M.1
Lassmann, H.2
-
9
-
-
84862741839
-
Inflammatory cell trafficking across the blood-brain barrier: Chemokine regulation and in vitro models
-
Takeshita Y, Ransohoff RM (2012) Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models. Immunol Rev 248, 228-39.
-
(2012)
Immunol Rev
, vol.248
, pp. 228-239
-
-
Takeshita, Y.1
Ransohoff, R.M.2
-
10
-
-
78650173611
-
Disruption of central nervous system barriers in multiple sclerosis
-
Alvarez JI, Cayrol R, Prat A (2011) Disruption of central nervous system barriers in multiple sclerosis. Biochim Biophys Acta 1812, 252-64.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 252-264
-
-
Alvarez, J.I.1
Cayrol, R.2
Prat, A.3
-
11
-
-
81755179424
-
How do immune cells overcome the blood-brain barrier in multiple sclerosis?
-
Larochelle C, Alvarez JI, Prat A (2011) How do immune cells overcome the blood-brain barrier in multiple sclerosis? FEBS Lett 585, 3770-80.
-
(2011)
FEBS Lett
, vol.585
, pp. 3770-3780
-
-
Larochelle, C.1
Alvarez, J.I.2
Prat, A.3
-
12
-
-
0141926694
-
Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination
-
DOI 10.1002/path.1434
-
Kirk J, Plumb J, Mirakhur M, McQuaid S (2003) Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination. J Pathol 201, 319-27. (Pubitemid 37258943)
-
(2003)
Journal of Pathology
, vol.201
, Issue.2
, pp. 319-327
-
-
Kirk, J.1
Plumb, J.2
Mirakhur, M.3
McQuaid, S.4
-
13
-
-
0036211141
-
Abnormal endothelial tight junctions in active lesions and normal-appearing white matter in multiple sclerosis
-
Plumb J, McQuaid S, Mirakhur M, Kirk J (2002) Abnormal endothelial tight junctions in active lesions and normal-appearing white matter in multiple sclerosis. Brain Pathol 12, 154-69. (Pubitemid 34259917)
-
(2002)
Brain Pathology
, vol.12
, Issue.2
, pp. 154-169
-
-
Plumb, J.1
McQuaid, S.2
Mirakhur, M.3
Kirk, J.4
-
14
-
-
33846134731
-
Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis
-
DOI 10.1111/j.1365-2990.2006.00781.x
-
Leech S, Kirk J, Plumb J, McQuaid S (2007) Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis. Neuropathol Appl Neurobiol 33, 86-98. (Pubitemid 46090313)
-
(2007)
Neuropathology and Applied Neurobiology
, vol.33
, Issue.1
, pp. 86-98
-
-
Leech, S.1
Kirk, J.2
Plumb, J.3
McQuaid, S.4
-
15
-
-
0031798063
-
Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis
-
Leppert D, Ford J, Stabler G, Grygar C, Lienert C, et al. (1998) Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis. Brain 121, 2327-34. (Pubitemid 28552469)
-
(1998)
Brain
, vol.121
, Issue.12
, pp. 2327-2334
-
-
Leppert, D.1
Ford, J.2
Stabler, G.3
Grygar, C.4
Lienert, C.5
Huber, S.6
Miller, K.M.7
Hauser, S.L.8
Kappos, L.9
-
16
-
-
84899785884
-
The Blood-Brain Barrier in Neuroinflammation
-
Suzumura A, Ikenaka K, editors. New York, NY: Springer Science+Business Media New York
-
Shimizu F, Kanda T (2013) The Blood-Brain Barrier in Neuroinflammation. In Suzumura A, Ikenaka K, editors. Neuron-Glia Interaction in Neuroinflammation. New York, NY: Springer Science+Business Media New York. pp. 157-79.
-
(2013)
Neuron-Glia Interaction in Neuroinflammation
, pp. 157-179
-
-
Shimizu, F.1
Kanda, T.2
-
17
-
-
0343812072
-
Relating matrix metalloproteinase structure to function: Why the 'Hemopexin' domain?
-
DOI 10.1016/S0945-053X(97)90025-1
-
Murphy G, Knäuper V (1997) Relating matrix metalloproteinase structure to function: why the "hemopexin" domain? Matrix Biol 15, 511-8. (Pubitemid 27190025)
-
(1997)
Matrix Biology
, vol.15
, Issue.8-9
, pp. 511-518
-
-
Murphy, G.1
Knauper, V.2
-
18
-
-
79952501096
-
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
-
Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, et al. (2011) Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 69, 292-302.
-
(2011)
Ann Neurol
, vol.69
, pp. 292-302
-
-
Polman, C.H.1
Reingold, S.C.2
Banwell, B.3
Clanet, M.4
Cohen, J.A.5
-
19
-
-
77956513445
-
Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function
-
Sano Y, Shimizu F, Abe M, Maeda T, Kashiwamura Y, et al. (2010) Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function. J Cell Physiol 225, 519-28.
-
(2010)
J Cell Physiol
, vol.225
, pp. 519-528
-
-
Sano, Y.1
Shimizu, F.2
Abe, M.3
Maeda, T.4
Kashiwamura, Y.5
-
20
-
-
0037648580
-
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
-
DOI 10.1083/jcb.200302070
-
Nitta T, Hata M, Gotoh S, Seo Y, Sasaki H, et al. (2003) Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol 161, 653-60. (Pubitemid 36578587)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.3
, pp. 653-660
-
-
Nitta, T.1
Hata, M.2
Gotoh, S.3
Seo, Y.4
Sasaki, H.5
Hashimoto, N.6
Furuse, M.7
Tsukita, S.8
-
21
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
DOI 10.1038/nrn1824
-
Abbott NJ, Rönnbäck L, Hansson E (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7, 41-53. (Pubitemid 41828930)
-
(2006)
Nature Reviews Neuroscience
, vol.7
, Issue.1
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
22
-
-
78751706537
-
T cell migration into the central nervous system during health and disease: Different molecular keys allow access to different central nervous system compartments
-
Engelhardt B (2010) T cell migration into the central nervous system during health and disease: Different molecular keys allow access to different central nervous system compartments. Clin Exp Neuroimmunol 1, 79-93.
-
(2010)
Clin Exp Neuroimmunol
, vol.1
, pp. 79-93
-
-
Engelhardt, B.1
-
23
-
-
0038660123
-
Serum from patients with multiple sclerosis downregulates occludin and VE-cadherin expression in cultured endothelial cells
-
DOI 10.1191/1352458503ms916oa
-
Minagar A, Ostanin D, Long AC, Jennings M, Kelley RE, et al. (2003) Serum from patients with multiple sclerosis downregulates occludin and VE-cadherin expression in cultured endothelial cells. Mult Scler 9, 235-8. (Pubitemid 36681887)
-
(2003)
Multiple Sclerosis
, vol.9
, Issue.3
, pp. 235-238
-
-
Minagar, A.1
Ostanin, D.2
Long, A.C.3
Jennings, M.4
Kelley, R.E.5
Sasaki, M.6
Alexander, J.S.7
-
24
-
-
33748568160
-
Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis
-
DOI 10.1097/01.jnen.0000235119.52311.16, PII 0000507220060900000003
-
Hochmeister S, Grundtner R, Bauer J, Engelhardt B, Lyck R, et al. (2006) Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis. J Neuropathol Exp Neurol 65, 855-65. (Pubitemid 44371231)
-
(2006)
Journal of Neuropathology and Experimental Neurology
, vol.65
, Issue.9
, pp. 855-865
-
-
Hochmeister, S.1
Grundtner, R.2
Bauer, J.3
Engelhardt, B.4
Lyck, R.5
Gordon, G.6
Korosec, T.7
Kutzelnigg, A.8
Berger, J.J.9
Bradl, M.10
Bittner, R.E.11
Lassmann, H.12
-
25
-
-
84857057493
-
Sera from neuromyelitis optica patients disrupt the blood-brain barrier
-
Shimizu F, Sano Y, Takahashi T, Haruki H, Saito K, et al. (2012) Sera from neuromyelitis optica patients disrupt the blood-brain barrier. J Neurol Neurosurg Psychiatry 83, 288-97.
-
(2012)
J Neurol Neurosurg Psychiatry
, vol.83
, pp. 288-297
-
-
Shimizu, F.1
Sano, Y.2
Takahashi, T.3
Haruki, H.4
Saito, K.5
-
26
-
-
60649108674
-
VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
-
Argaw AT, Gurfein BT, Zhang Y, Zameer A, John GR (2009) VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown. Proc Natl Acad Sci U S A 106, 1977-82.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1977-1982
-
-
Argaw, A.T.1
Gurfein, B.T.2
Zhang, Y.3
Zameer, A.4
John, G.R.5
-
27
-
-
84863547119
-
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
-
Argaw AT, Asp L, Zhang J, Navrazhina K, Pham T, et al. (2012) Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease. J Clin Invest 122, 2454-68.
-
(2012)
J Clin Invest
, vol.122
, pp. 2454-2468
-
-
Argaw, A.T.1
Asp, L.2
Zhang, J.3
Navrazhina, K.4
Pham, T.5
-
28
-
-
33645092394
-
Upregulation of vascular growth factors in multiple sclerosis: Correlation with MRI findings
-
Su JJ, Osoegawa M, Matsuoka T, Minohara M, Tanaka M, et al. (2006) Upregulation of vascular growth factors in multiple sclerosis: correlation with MRI findings. J Neurol Sci 243, 21-30.
-
(2006)
J Neurol Sci
, vol.243
, pp. 21-30
-
-
Su, J.J.1
Osoegawa, M.2
Matsuoka, T.3
Minohara, M.4
Tanaka, M.5
-
29
-
-
61849164425
-
Matrix metalloproteinase-9 and matrix metalloproteinase-2 as biomarkers of various courses in multiple sclerosis
-
Benesová Y, Vasku A, Novotná H, Litzman J, Stourac P, et al. (2009) Matrix metalloproteinase-9 and matrix metalloproteinase-2 as biomarkers of various courses in multiple sclerosis. Mult Scler 15, 316-22.
-
(2009)
Mult Scler
, vol.15
, pp. 316-322
-
-
Benesová, Y.1
Vasku, A.2
Novotná, H.3
Litzman, J.4
Stourac, P.5
-
30
-
-
0027944171
-
Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases
-
Gijbels K, Galargy RE, Steinman L (1994) Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteinases. J Clin Invest 94, 2177-82. (Pubitemid 24379586)
-
(1994)
Journal of Clinical Investigation
, vol.94
, Issue.6
, pp. 2177-2182
-
-
Gijbels, K.1
Galardy, R.E.2
Steinman, L.3
-
31
-
-
48249139449
-
Multiple sclerosis: An immune or neurodegenerative disorder?
-
Trapp BD, Nave KA (2008) Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 31, 247-69.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.A.2
-
32
-
-
0038182547
-
Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis
-
DOI 10.1016/S0896-6273(03)00326-X
-
Zamvil SS, Steinman L (2003) Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis. Neuron 38, 685-8. (Pubitemid 36694776)
-
(2003)
Neuron
, vol.38
, Issue.5
, pp. 685-688
-
-
Zamvil, S.S.1
Steinman, L.2
-
33
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic BV (2008) The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57, 178-201.
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
34
-
-
0029319566
-
Cytokine localization in multiple sclerosis lesions: Correlation with adhesion molecule expression and reactive nitrogen species
-
Brosnan CF, Cannella B, Battistini L, Raine CS (1995) Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species. Neurology 45, S16-21.
-
(1995)
Neurology
, vol.45
-
-
Brosnan, C.F.1
Cannella, B.2
Battistini, L.3
Raine, C.S.4
-
35
-
-
37149030961
-
4-integrins in multiple sclerosis
-
DOI 10.1159/000109933
-
Engelhardt B, Kappos L (2008) Natalizumab: targeting alpha4-integrins in multiple sclerosis. Neurodegener Dis 5, 16-22. (Pubitemid 350261811)
-
(2008)
Neurodegenerative Diseases
, vol.5
, Issue.1
, pp. 16-22
-
-
Engelhardt, B.1
Kappos, L.2
-
36
-
-
34247513840
-
MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS
-
DOI 10.1212/01.wnl.0000260064.77700.fd, PII 0000611420070424000012
-
Miller DH, Soon D, Fernando KT, MacManus DG, Barker GJ, et al. (2007) MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS. Neurology 68, 1390-401. (Pubitemid 46659091)
-
(2007)
Neurology
, vol.68
, Issue.17
, pp. 1390-1401
-
-
Miller, D.H.1
Soon, D.2
Fernando, K.T.3
MacManus, D.G.4
Barker, G.J.5
Yousry, T.A.6
Fisher, E.7
O'Connor, P.W.8
Phillips, J.T.9
Polman, C.H.10
Kappos, L.11
Hutchinson, M.12
Havrdova, E.13
Lublin, F.D.14
Giovannoni, G.15
Wajgt, A.16
Rudick, R.17
Lynn, F.18
Panzara, M.A.19
Sandrock, A.W.20
more..
-
37
-
-
84871881788
-
Impact of natalizumab on ambulatory improvement in secondary progressive and disabled relapsing-remitting multiple sclerosis
-
Cadavid D, Jurgensen S, Lee S (2013) Impact of natalizumab on ambulatory improvement in secondary progressive and disabled relapsing-remitting multiple sclerosis. PLoS One 8, e53297.
-
(2013)
PLoS One
, vol.8
-
-
Cadavid, D.1
Jurgensen, S.2
Lee, S.3
|