Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression

Autophagy

Volumn 10, Issue 5, 2014, Pages 766-784

  Wang, Ji ^a   Kang, Rongyan ^a   Huang, He ^a   Xi, Xueyan ^a   Wang, Bei ^a   Wang, Jianwei ^a   Zhao, Zhendong ^a  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

Author keywords

Autophagy; Core; ER stress; Hepatitis C virus; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 12; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; BETA ACTIN; CORE PROTEIN; EUKARYOTIC TRANSLATION INITIATION FACTOR 2ALPHA KINASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3BETA; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5B; PROTEIN; UNCLASSIFIED DRUG; ATF6 PROTEIN, HUMAN; ATG12 PROTEIN, HUMAN; DDIT3 PROTEIN, HUMAN; EIF2AK3 PROTEIN, HUMAN; MAP1LC3B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; NUCLEOCAPSID PROTEIN, HEPATITIS C VIRUS; PROTEIN KINASE R; SMALL INTERFERING RNA; SUMO PROTEIN;

ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HEPATITIS C VIRUS; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; UNFOLDED PROTEIN RESPONSE; UPREGULATION; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 6; AUTOPHAGY; CELLS, CULTURED; EIF-2 KINASE; GENE EXPRESSION REGULATION; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE; VIRAL CORE PROTEINS;

EID: 84899757673     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.27954     Document Type: Article

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