Carbocisteine reduces virus-induced pulmonary inflammation in mice exposed to cigarette smoke

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 5, 2014, Pages 963-973

  Yageta, Yuichi ^a,d   Ishii, Yukio ^a   Morishima, Yuko ^a   Ano, Satoshi ^a   Ohtsuka, Shigeo ^a   Matsuyama, Masashi ^a   Takeuchi, Kaoru ^a   Itoh, Ken ^b   Yamamoto, Masayuki ^c   Hizawa, Nobuyuki ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d Discovery Research Laboratories Kyorin Pharmaceutical Company Limited   (Japan)

Author keywords

Carbocisteine; Chronic obstructive pulmonary disease exacerbation; Influenza A virus; Macrophages; NF E2 related factor 2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CARBOCISTEINE; CIGARETTE SMOKE; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; GOBLET CELL; INFLAMMATORY INFILTRATE; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; MACROPHAGE CULTURE; MOUSE; MUCUS SECRETION; NONHUMAN; OXIDATIVE STRESS; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; PROTEIN TRANSPORT; VIRUS PNEUMONIA;

ANIMALS; ANTIOXIDANTS; CARBOCYSTEINE; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; ORTHOMYXOVIRIDAE; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PNEUMONIA; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY ALVEOLI; SMOKING;

EID: 84899757607     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0292OC     Document Type: Article

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