Nobiletin, a flavone from Citrus depressa, induces gene expression and increases the protein level and activity of neprilysin in SK-N-SH cells

Canadian Journal of Physiology and Pharmacology

Volumn 92, Issue 5, 2014, Pages 351-355

  Fujiwara, Hironori ^a,h   Kimura, Junko ^b   Sakamoto, Masahiro ^a   Yokosuka, Akihito ^c   Mimaki, Yoshihiro ^c   Murata, Kiyoshi ^d   Yamaguchi, Kikuji ^a,e,f   Ohizumi, Yasushi ^a,b,g  

^a TOHOKU UNIVERSITY   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d R and D Center   (Japan)

^e Japan Royal Jelly (JRJ) Co Ltd   (Japan)

^f YUNNAN AGRICULTURAL UNIVERSITY   (China)

^g YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^h UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Alzheimer's disease; Amyloid protein; Citrus depressa; Dementia; Neprilysin; Nobiletin; SK N SH cells

Indexed keywords

BETA ACTIN; MEMBRANE METALLOENDOPEPTIDASE; NOBILETIN; ANTIOXIDANT; FLAVONE DERIVATIVE;

ARTICLE; CELL PROLIFERATION; CITRUS; CITRUS DEPRESSA; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM;

ANTIOXIDANTS; CELL LINE; CITRUS; FLAVONES; GENE EXPRESSION; HUMANS; NEPRILYSIN;

EID: 84899736631     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2013-0440     Document Type: Article

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