-
1
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science. 2002;297:353-356. (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
2
-
-
85047694516
-
Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment
-
DOI 10.1172/JCI200422831
-
Gong B., Vitolo O.V., Trinchese F., Liu S., Shelanski M., Arancio O. Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment. J Clin Invest. 2004;114:1624-1634. (Pubitemid 40385553)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.11
, pp. 1624-1634
-
-
Gong, B.1
Vitolo, O.V.2
Trinchese, F.3
Liu, S.4
Shelanski, M.5
Arancio, O.6
-
3
-
-
0029898252
-
Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus
-
Impey S., Mark M., Villacres E.C., Poser S., Chavkin C., Storm D.R. Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron. 1996;16:973-982.
-
(1996)
Neuron
, vol.16
, pp. 973-982
-
-
Impey, S.1
Mark, M.2
Villacres, E.C.3
Poser, S.4
Chavkin, C.5
Storm, D.R.6
-
4
-
-
4243105077
-
IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells
-
DOI 10.1124/jpet.104.065979
-
Fujiwara H., Yamakuni T., Ueno M., Ishizuka M., Shinkawa T., Ohizumi Y., et al. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells. J Pharmacol Exp Ther. 2004;310:1288-1295. (Pubitemid 39108952)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.310
, Issue.3
, pp. 1288-1295
-
-
Fujiwara, H.1
Yamakuni, T.2
Ueno, M.3
Ishizuka, M.4
Shinkawa, T.5
Isobe, T.6
Ohizumi, Y.7
-
6
-
-
0030954604
-
Application of physiologically active substances isolated from natural resources to pharmacological studies
-
Ohizumi Y. Application of physiologically active substances isolated from natural resources to pharmacological studies. Jpn J Pharmacol. 1997;73:263-289. (Pubitemid 27226159)
-
(1997)
Japanese Journal of Pharmacology
, vol.73
, Issue.4
, pp. 263-289
-
-
Ohizumi, Y.1
-
7
-
-
0027157178
-
FK506 and ciclosporin: Molecular probes for studying intracellular signal transduction
-
Liu J. FK506 and cyclosporin: Molecular probes for studying intracellular signal transduction. Trends Pharmacol Sci. 1993;14:182-188. (Pubitemid 23168862)
-
(1993)
Trends in Pharmacological Sciences
, vol.14
, Issue.5
, pp. 182-188
-
-
Liu, J.1
-
8
-
-
84952513836
-
Composition of freshly harvested and commercial royal jelly
-
Hove S.R., Dimick P.S., Benton A.W. Composition of freshly harvested and commercial royal jelly. J Apic Res. 1985;24:52-61.
-
(1985)
J Apic Res
, vol.24
, pp. 52-61
-
-
Hove, S.R.1
Dimick, P.S.2
Benton, A.W.3
-
9
-
-
16544368439
-
Antihypertensive effect of peptides from Royal Jelly in spontaneously hypertensive rats
-
DOI 10.1248/bpb.27.189
-
Tokunaga K.H., Yoshida C., Suzuki K.M., Maruyama H., Futamura Y., Mishima S., et al. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol Pharm Bull. 2004;27:189-192. (Pubitemid 41694696)
-
(2004)
Biological and Pharmaceutical Bulletin
, vol.27
, Issue.2
, pp. 189-192
-
-
Tokunaga, K.1
Yoshida, C.2
Suzuki, K.3
Maruyama, H.4
Futamura, Y.5
Araki, Y.6
Mishima, S.7
-
10
-
-
33847124925
-
Pharmacological basis of traditional medicines and health supplements as curatives
-
DOI 10.1254/jphs.CPJ06016X
-
Miyata T. Pharmacological basis of traditional medicines and health supplements as curatives. J Pharmacol Sci. 2007;103:127-131. (Pubitemid 46294640)
-
(2007)
Journal of Pharmacological Sciences
, vol.103
, Issue.2
, pp. 127-131
-
-
Miyata, T.1
-
11
-
-
27144554955
-
Nobiletin and its related flavonoids with CRE-dependent transcription-stimulating and neuritegenic activities
-
DOI 10.1016/j.bbrc.2005.10.001, PII S0006291X0502228X
-
Nagase H., Omae N., Omori A., Nakagawasai O., Tadano T., Ohizumi Y., et al. Nobiletin and its related flavonoids with CRE-dependent transcription- stimulating and neuritegenic activities. Biochem Biophys Res Commun. 2005;337:1330-1336. (Pubitemid 41505268)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.337
, Issue.4
, pp. 1330-1336
-
-
Nagase, H.1
Omae, N.2
Omori, A.3
Nakagawasai, O.4
Tadano, T.5
Yokosuka, A.6
Sashida, Y.7
Mimaki, Y.8
Yamakuni, T.9
Ohizumi, Y.10
-
12
-
-
34648824442
-
Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice
-
DOI 10.1254/jphs.SC0070155
-
Nakajima A., Yamakuni T., Haraguchi M., Tadano T., Mimaki Y., Ohizumi Y., et al. Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice. J Pharmacol Sci. 2007;105:122-126. (Pubitemid 47463532)
-
(2007)
Journal of Pharmacological Sciences
, vol.105
, Issue.1
, pp. 122-126
-
-
Nakajima, A.1
Yamakuni, T.2
Haraguchi, M.3
Omae, N.4
Song, S.-Y.5
Kato, C.6
Nakagawasai, O.7
Tadano, T.8
Yokosuka, A.9
Mimaki, Y.10
Sashida, Y.11
Ohizumi, Y.12
-
13
-
-
51049094168
-
Innovation of natural beekeeping and quality control of bee products for promising apiculture. 1. Current problems of beekeeping and recurrence of natural bee-culture for resolution of the problems
-
Yamaguchi K. Innovation of natural beekeeping and quality control of bee products for promising apiculture. 1. Current problems of beekeeping and recurrence of natural bee-culture for resolution of the problems. J Yunnan Agric Univ. 2004;19:322-329.
-
(2004)
J Yunnan Agric Univ
, vol.19
, pp. 322-329
-
-
Yamaguchi, K.1
-
14
-
-
33646127159
-
Identification of AMP N1-oxide in royal jelly as a component neurotrophic toward cultured rat pheochromocytoma PC12 cells
-
Hattori N., Nomoto H., Mishima S., Inagaki S., Goto M., Furukawa S., et al. Identification of AMP N1-oxide in royal jelly as a component neurotrophic toward cultured rat pheochromocytoma PC12 cells. Biosci Biotechnol Biochem. 2006;70:897-906.
-
(2006)
Biosci Biotechnol Biochem
, vol.70
, pp. 897-906
-
-
Hattori, N.1
Nomoto, H.2
Mishima, S.3
Inagaki, S.4
Goto, M.5
Furukawa, S.6
-
15
-
-
68849106033
-
4′-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade
-
Al Rahim M., Nakajima A., Saigusa D., Tetsu N., Ohizumi Y., Yamakuni T., et al. 4′-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade. Biochemistry. 2009;48:7713-7721.
-
(2009)
Biochemistry
, vol.48
, pp. 7713-7721
-
-
Al Rahim, M.1
Nakajima, A.2
Saigusa, D.3
Tetsu, N.4
Ohizumi, Y.5
Yamakuni, T.6
|