Protective effects of combined intervention with adenovirus vector mediated IL-10 and IGF-1 genes on endogenous islet β cells in nonobese diabetes mice with onset of type 1 diabetes mellitus

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Zhang, Lijuan ^a   Chen, Yanyan ^b   Li, Cheng ^a   Lin, Xiaojie ^a   Cheng, Xiaoli ^c   Li, Tang ^a  

^a QINGDAO UNIVERSITY   (China)

^b PEOPLE S HOSPITAL OF RIZHAO   (China)

^c Department of Medical Center Qingdao Sanatorium of Shandong Province ^*  (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; C PEPTIDE; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 10; INTERLEUKIN 4; SOMATOMEDIN C; GLUCOSE BLOOD LEVEL;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MASS; BODY WEIGHT; CELL PROTECTION; CONTROLLED STUDY; DIABETES CONTROL; FEMALE; GENDER; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; HUMAN; HUMAN CELL; IGF 1 GENE; IL 10 GENE; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; NONHUMAN; NONOBESE DIABETIC MOUSE; ONSET AGE; PANCREAS; PANCREAS ISLET BETA CELL; PROTEIN BLOOD LEVEL; TISSUE LEVEL; ADENOVIRIDAE; ANIMAL; BLOOD; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION REGULATION; GENE THERAPY; GENE VECTOR; GENETICS; METABOLISM; MOUSE; PANCREAS ISLET; PATHOLOGY;

ADENOVIRIDAE; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 1; FEMALE; GENE EXPRESSION REGULATION; GENETIC THERAPY; GENETIC VECTORS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-10; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD;

EID: 84899725435     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092616     Document Type: Article

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