-
1
-
-
84883869700
-
Do HIV-specific CTL continue to have an antiviral function during antiretroviral therapy? if not, why not, and what can be done about it
-
McIlroy D (2013) Do HIV-specific CTL continue to have an antiviral function during antiretroviral therapy? If not, why not, and what can be done about it? Front Immunol 4: 52.
-
(2013)
Front Immunol
, vol.4
, pp. 52
-
-
McIlroy, D.1
-
2
-
-
79955468799
-
Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control
-
Hersperger AR, Migueles SA, Betts MR, Connors M (2011) Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control. Curr Opin HIV AIDS 6: 169-173.
-
(2011)
Curr Opin HIV AIDS
, vol.6
, pp. 169-173
-
-
Hersperger, A.R.1
Migueles, S.A.2
Betts, M.R.3
Connors, M.4
-
3
-
-
34548689151
-
Human Immunodeficiency Virus Controllers: Mechanisms of Durable Virus Control in the Absence of Antiretroviral Therapy
-
DOI 10.1016/j.immuni.2007.08.010, PII S1074761307004141
-
Deeks SG, Walker BD (2007) Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27: 406-416. (Pubitemid 47418678)
-
(2007)
Immunity
, vol.27
, Issue.3
, pp. 406-416
-
-
Deeks, S.G.1
Walker, B.D.2
-
4
-
-
0030659177
-
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
-
DOI 10.1073/pnas.94.24.13193
-
Chun TW, Stuyver L, Mizell SB, Ehler LA, Mican JA, et al. (1997) Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc Natl Acad Sci U S A 94: 13193-13197. (Pubitemid 27518498)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.24
, pp. 13193-13197
-
-
Chun, T.-W.1
Stuyver, L.2
Mizell, S.B.3
Ehler, L.A.4
Mican, J.A.M.5
Baseler, M.6
Lloyd, A.L.7
Nowak, M.A.8
Fauci, A.S.9
-
5
-
-
14444273439
-
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
-
DOI 10.1126/science.278.5341.1295
-
Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, et al. (1997) Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278: 1295-1300. (Pubitemid 27495742)
-
(1997)
Science
, vol.278
, Issue.5341
, pp. 1295-1300
-
-
Finzi, D.1
Hermankova, M.2
Pierson, T.3
Carruth, L.M.4
Buck, C.5
Chaisson, R.E.6
Quinn, T.C.7
Chadwick, K.8
Margolick, J.9
Brookmeyer, R.10
Gallant, J.11
Markowitz, M.12
Ho, D.D.13
Richman, D.D.14
Siliciano, R.F.15
-
6
-
-
0038579210
-
+ T cells
-
DOI 10.1038/nm880
-
Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, et al. (2003) Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 9: 727-728. (Pubitemid 36749221)
-
(2003)
Nature Medicine
, vol.9
, Issue.6
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
Quinn, T.C.4
Chadwick, K.5
Margolick, J.B.6
Kovacs, C.7
Gange, S.J.8
Siliciano, R.F.9
-
7
-
-
84858790935
-
Small molecules and big killers: The challenge of eliminating the latent HIV reservoir
-
Migueles SA, Connors M (2012) Small molecules and big killers: the challenge of eliminating the latent HIV reservoir. Immunity 36: 320-321.
-
(2012)
Immunity
, vol.36
, pp. 320-321
-
-
Migueles, S.A.1
Connors, M.2
-
8
-
-
84863337769
-
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
-
Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, et al. (2012) Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 36: 491-501.
-
(2012)
Immunity
, vol.36
, pp. 491-501
-
-
Shan, L.1
Deng, K.2
Shroff, N.S.3
Durand, C.M.4
Rabi, S.A.5
-
10
-
-
84877058009
-
Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8+ T cell function in vitro
-
Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, et al. (2013) Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8+ T cell function in vitro. J Leukoc Biol.
-
(2013)
J Leukoc Biol
-
-
Siewe, B.1
Stapleton, J.T.2
Martinson, J.3
Keshavarzian, A.4
Kazmi, N.5
-
11
-
-
84867308365
-
IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection
-
Das A, Ellis G, Pallant C, Lopes AR, Khanna P, et al. (2012) IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection. J Immunol 189: 3925-3935.
-
(2012)
J Immunol
, vol.189
, pp. 3925-3935
-
-
Das, A.1
Ellis, G.2
Pallant, C.3
Lopes, A.R.4
Khanna, P.5
-
12
-
-
84864771090
-
Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling
-
Ahmed KA, Wang L, Munegowda MA, Mulligan SJ, Gordon JR, et al. (2012) Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling. J Leukoc Biol 92: 289-300.
-
(2012)
J Leukoc Biol
, vol.92
, pp. 289-300
-
-
Ahmed, K.A.1
Wang, L.2
Munegowda, M.A.3
Mulligan, S.J.4
Gordon, J.R.5
-
13
-
-
77957164949
-
IL-10 produced by activated human B cells regulates CD4(+) T-cell activation in vitro
-
Bouaziz JD, Calbo S, Maho-Vaillant M, Saussine A, Bagot M, et al. IL-10 produced by activated human B cells regulates CD4(+) T-cell activation in vitro. Eur J Immunol 40: 2686-2691.
-
Eur J Immunol
, vol.40
, pp. 2686-2691
-
-
Bouaziz, J.D.1
Calbo, S.2
Maho-Vaillant, M.3
Saussine, A.4
Bagot, M.5
-
14
-
-
84855597096
-
Maturation and function of human dendritic cells are regulated by B lymphocytes
-
Morva A, Lemoine S, Achour A, Pers JO, Youinou P, et al. (2012) Maturation and function of human dendritic cells are regulated by B lymphocytes. Blood 119: 106-114.
-
(2012)
Blood
, vol.119
, pp. 106-114
-
-
Morva, A.1
Lemoine, S.2
Achour, A.3
Pers, J.O.4
Youinou, P.5
-
15
-
-
77956895769
-
Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis
-
Matsushita T, Horikawa M, Iwata Y, Tedder TF (2010) Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis. J Immunol 185: 2240-2252.
-
(2010)
J Immunol
, vol.185
, pp. 2240-2252
-
-
Matsushita, T.1
Horikawa, M.2
Iwata, Y.3
Tedder, T.F.4
-
16
-
-
60849127627
-
Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid
-
Archin NM, Espeseth A, Parker D, Cheema M, Hazuda D, et al. (2009) Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. AIDS Res Hum Retroviruses 25: 207-212.
-
(2009)
AIDS Res Hum Retroviruses
, vol.25
, pp. 207-212
-
-
Archin, N.M.1
Espeseth, A.2
Parker, D.3
Cheema, M.4
Hazuda, D.5
-
17
-
-
65449148344
-
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells
-
Contreras X, Schweneker M, Chen CS, McCune JM, Deeks SG, et al. (2009) Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells. J Biol Chem 284: 6782-6789.
-
(2009)
J Biol Chem
, vol.284
, pp. 6782-6789
-
-
Contreras, X.1
Schweneker, M.2
Chen, C.S.3
McCune, J.M.4
Deeks, S.G.5
-
18
-
-
84864203255
-
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
-
Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, et al. (2012) Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487: 482-485.
-
(2012)
Nature
, vol.487
, pp. 482-485
-
-
Archin, N.M.1
Liberty, A.L.2
Kashuba, A.D.3
Choudhary, S.K.4
Kuruc, J.D.5
-
19
-
-
0028337166
-
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
-
Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, et al. (1994) Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 68: 4650-4655. (Pubitemid 24183063)
-
(1994)
Journal of Virology
, vol.68
, Issue.7
, pp. 4650-4655
-
-
Koup, R.A.1
Safrit, J.T.2
Cao, Y.3
Andrews, C.A.4
McLeod, G.5
Borkowsky, W.6
Farthing, C.7
Ho, D.D.8
-
20
-
-
0028950823
-
Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: A longitudinal analysis of rapid progressors and long-term asymptomatics
-
Klein MR, van Baalen CA, Holwerda AM, Kerkhof Garde SR, Bende RJ, et al. (1995) Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics. J Exp Med 181: 1365-1372.
-
(1995)
J Exp Med
, vol.181
, pp. 1365-1372
-
-
Klein, M.R.1
Van Baalen, C.A.2
Holwerda, A.M.3
Kerkhof Garde, S.R.4
Bende, R.J.5
-
21
-
-
0030997137
-
+ cells: Evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms
-
Yang OO, Kalams SA, Trocha A, Cao H, Luster A, et al. (1997) Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms. J Virol 71: 3120-3128. (Pubitemid 27119959)
-
(1997)
Journal of Virology
, vol.71
, Issue.4
, pp. 3120-3128
-
-
Yang, O.O.1
Kalams, S.A.2
Trocha, A.3
Cao, H.4
Luster, A.5
Johnson, R.P.6
Walker, B.D.7
-
22
-
-
77950525439
-
Programmed death-1- induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection
-
Said EA, Dupuy FP, Trautmann L, Zhang Y, Shi Y, et al. Programmed death-1- induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nat Med 16: 452-459.
-
Nat Med
, vol.16
, pp. 452-459
-
-
Said, E.A.1
Dupuy, F.P.2
Trautmann, L.3
Zhang, Y.4
Shi, Y.5
-
23
-
-
33749009709
-
+ T cells leads to reversible immune dysfunction
-
DOI 10.1038/nm1482, PII NM1482
-
Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, et al. (2006) Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med 12: 1198-1202. (Pubitemid 44527357)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.-R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
Routy, J.-P.11
Haddad, E.K.12
Sekaly, R.-P.13
-
24
-
-
34250662666
-
Programmed death 1: A critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections
-
DOI 10.1097/COH.0b013e3280ebb5c9, PII 0122292920070500000009
-
Trautmann L, Said EA, Halwani R, Janbazian L, Chomont N, et al. (2007) Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections. Curr Opin HIV AIDS 2: 219-227. (Pubitemid 46941121)
-
(2007)
Current Opinion in HIV and AIDS
, vol.2
, Issue.3
, pp. 219-227
-
-
Trautmann, L.1
Said, E.A.2
Halwani, R.3
Janbazian, L.4
Chomont, N.5
El-Far, M.6
Breton, G.7
Haddad, E.K.8
Sekaly, R.-P.9
-
25
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
DOI 10.1038/nature05115, PII NATURE05115
-
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350-354. (Pubitemid 44435155)
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.R.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
26
-
-
62249172189
-
Enhancing SIVspecific immunity in vivo by PD-1 blockade
-
Velu V, Titanji K, Zhu B, Husain S, Pladevega A, et al. (2009) Enhancing SIVspecific immunity in vivo by PD-1 blockade. Nature 458: 206-210.
-
(2009)
Nature
, vol.458
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
Husain, S.4
Pladevega, A.5
-
27
-
-
84871844273
-
In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice
-
Palmer BE, Neff CP, Lecureux J, Ehler A, Dsouza M, et al. (2013) In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice. J Immunol 190: 211-219.
-
(2013)
J Immunol
, vol.190
, pp. 211-219
-
-
Palmer, B.E.1
Neff, C.P.2
Lecureux, J.3
Ehler, A.4
Dsouza, M.5
-
28
-
-
67651087322
-
IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells
-
Brockman MA, Kwon DS, Tighe DP, Pavlik DF, Rosato PC, et al. (2009) IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells. Blood 114: 346-356.
-
(2009)
Blood
, vol.114
, pp. 346-356
-
-
Brockman, M.A.1
Kwon, D.S.2
Tighe, D.P.3
Pavlik, D.F.4
Rosato, P.C.5
-
29
-
-
84877058009
-
Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8(+) T cell function in vitro
-
Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, et al. (2013) Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8(+) T cell function in vitro. J Leukoc Biol 93: 811-818.
-
(2013)
J Leukoc Biol
, vol.93
, pp. 811-818
-
-
Siewe, B.1
Stapleton, J.T.2
Martinson, J.3
Keshavarzian, A.4
Kazmi, N.5
-
30
-
-
84859385739
-
Immune regulatory function of B cells
-
Mauri C, Bosma A (2012) Immune regulatory function of B cells. Annu Rev Immunol 30: 221-241.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 221-241
-
-
Mauri, C.1
Bosma, A.2
-
31
-
-
79953815120
-
Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression
-
Hersperger AR, Martin JN, Shin LY, Sheth PM, Kovacs CM, et al. (2011) Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. Blood 117: 3799-3808.
-
(2011)
Blood
, vol.117
, pp. 3799-3808
-
-
Hersperger, A.R.1
Martin, J.N.2
Shin, L.Y.3
Sheth, P.M.4
Kovacs, C.M.5
-
32
-
-
84875725016
-
IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses
-
van de Veen W, Stanic B, Yaman G, Wawrzyniak M, Sollner S, et al. (2013) IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses. J Allergy Clin Immunol 131: 1204-1212.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 1204-1212
-
-
VanDeVeen, W.1
Stanic, B.2
Yaman, G.3
Wawrzyniak, M.4
Sollner, S.5
-
33
-
-
58149484842
-
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection
-
Brooks DG, Ha SJ, Elsaesser H, Sharpe AH, Freeman GJ, et al. (2008) IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection. Proc Natl Acad Sci U S A 105: 20428-20433.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20428-20433
-
-
Brooks, D.G.1
Ha, S.J.2
Elsaesser, H.3
Sharpe, A.H.4
Freeman, G.J.5
-
34
-
-
84868619716
-
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
-
Yoshizaki A, Miyagaki T, DiLillo DJ, Matsushita T, Horikawa M, et al. (2012) Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. Nature 491: 264-268.
-
(2012)
Nature
, vol.491
, pp. 264-268
-
-
Yoshizaki, A.1
Miyagaki, T.2
Dilillo, D.J.3
Matsushita, T.4
Horikawa, M.5
-
35
-
-
84899700523
-
Kaufmann de Role of PD-1 in HIV Pathogenesis and as Target for Therapy
-
Porichis F, Kaufmann DE Role of PD-1 in HIV Pathogenesis and as Target for Therapy. Curr HIV/AIDS Rep.
-
Curr HIV/AIDS Rep
-
-
Porichis, F.1
-
36
-
-
84886944742
-
A new dynamic model of three cell interactions for CTL responses
-
Ahmed KA, Wang L, Xiang J (2012) A new dynamic model of three cell interactions for CTL responses. Oncoimmunology 1: 1430-1432.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1430-1432
-
-
Ahmed, K.A.1
Wang, L.2
Xiang, J.3
-
37
-
-
78751469622
-
Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
-
Iwata Y, Matsushita T, Horikawa M, Dilillo DJ, Yanaba K, et al. (2011) Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood 117: 530-541.
-
(2011)
Blood
, vol.117
, pp. 530-541
-
-
Iwata, Y.1
Matsushita, T.2
Horikawa, M.3
Dilillo, D.J.4
Yanaba, K.5
-
38
-
-
0030712305
-
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
-
DOI 10.1126/science.278.5341.1291
-
Wong JK, Hezareh M, Gunthard HF, Havlir DV, Ignacio CC, et al. (1997) Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278: 1291-1295. (Pubitemid 27495741)
-
(1997)
Science
, vol.278
, Issue.5341
, pp. 1291-1295
-
-
Wong, J.K.1
Hezareh, M.2
Gunthard, H.F.3
Havlir, D.V.4
Ignacio, C.C.5
Spina, C.A.6
Richman, D.D.7
-
39
-
-
84867308365
-
IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection
-
Das A, Ellis G, Pallant C, Lopes AR, Khanna P, et al (2012) IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection. J Immunol 189: 3925-3935.
-
(2012)
J Immunol
, vol.189
, pp. 3925-3935
-
-
Das, A.1
Ellis, G.2
Pallant, C.3
Lopes, A.R.4
Khanna, P.5
|