The CaV 2.3 r-type voltage-gated Ca2+ Channel n mouse sleep architecture

Sleep

Volumn 37, Issue 5, 2014, Pages

  Siwek, Magdalena Elisabeth ^a   Müller, Ralf ^b   Math, Dipl ^b   Henseler, Christina ^a   Broich, Karl ^a   Papazoglou, Anna ^a   Weiergräber, Marco ^a,b  

^a FEDERAL INSTITUTE FOR DRUGS AND MEDICAL DEVICES   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Rapid eye movement (REM); Slow wave sleep (SWS); Thalamocortical circuitry; Vigilance

Indexed keywords

CALCIUM; CALCIUM CHANNEL R TYPE; R TYPE VOLTAGE GATED CALCIUM CHANNEL CAV2.3; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL TYPE 2; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; CACNA1E PROTEIN, MOUSE; CATION TRANSPORT PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; EMBRYO; MEMBRANE CURRENT; MOUSE; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; SLEEP; SLEEP DEPRIVATION; SLEEP STAGE; SLOW WAVE SLEEP; SPIKE WAVE; TELEMETRY; THALAMOCORTICAL TRACT; THALAMUS RETICULAR NUCLEUS; ANIMAL; BRAIN CORTEX; CYTOLOGY; GENETICS; MALE; METABOLISM; NERVE CELL; PERIODICITY; PHYSIOLOGY; THALAMUS;

ANIMALS; CALCIUM CHANNELS, R-TYPE; CATION TRANSPORT PROTEINS; CEREBRAL CORTEX; ELECTROENCEPHALOGRAPHY; MALE; MICE; NEURONS; PERIODICITY; SLEEP; SLEEP STAGES; THALAMUS;

EID: 84899694039     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.5665/sleep.3652     Document Type: Article

References (59)

1. Bers DM, Weber CR. Na/Ca exchange function in intact ventricular myocytes. Ann N Y Acad Sci 2002;976:500-12
2. Yang SN, Berggren PO. Ca V 2.3 channel and PKClambda: new players in insulin secretion. J Clin Invest 2005;115:16-20
3. Catterall WA. Voltage-gated calcium channels. Cold Spring Harb Perspect Biol 2011;3:a003947
4. Hofmann F, Lacinova L, Klugbauer N. Voltage-dependent calcium channels: from structure to function. Rev Physiol Biochem Pharmacol 1999;139:33-87
5. Jones SW. Calcium channels: when is a subunit not a subunit? J Physiol 2002;545:334
6. Lopez-Bendito G, Molnar Z. Thalamocortical development: how are we going to get there? Nat Rev Neurosci 2003;4:276-89
7. Catterall WA, Striessnig J, Snutch TP, Perez-Reyes E. International Union of Pharmacology. XL. Compendium of voltage-gated ion channels: calcium channels. Pharmacol Rev 2003;55:579-81
8. Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol Rev 2005;57:411-25
9. Steriade M. Sleep, epilepsy and thalamic reticular inhibitory neurons. Trends Neurosci 2005;28:317-24
10. Llinas RR, Steriade M. Bursting of thalamic neurons and states of vigilance. J Neurophysiol 2006;95:3297-308
11. Beenhakker MP, Huguenard JR. Neurons that fire together also conspire together: is normal sleep circuitry hijacked to generate epilepsy? Neuron 2009;62:612-32
12. Shin HS, Lee J, Song I. Genetic studies on the role of T-type Ca2+ channels in sleep and absence epilepsy. CNS Neurol Disord Drug Targets 2006;5:629-38
13. Shin HS. T-type Ca2+ channels and absence epilepsy. Cell Calcium 2006;40:191-6
14. Cheong E, Shin HS. T-type Ca2+ channels in absence epilepsy. Biochim Biophys Acta 2013;1828:1560-71
15. Siwek M, Henseler C, Broich K, Papazoglou A, Weiergraber M. Voltagegated Ca2+channel mediated Ca2+ influx in epileptogenesis. Adv Exp Med Biol 2012;740:1219-47
16. Talley EM, Solorzano G, Depaulis A, Perez-Reyes E, Bayliss DA. Lowvoltage- activated calcium channel subunit expression in a genetic model of absence epilepsy in the rat. Brain Res Mol Brain Res 2000;75:159-65
17. Kim D, Song I, Keum S, et al. Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha1G T-type Ca2+ channels. Neuron 2001;31:35-45
18. Lee J, Kim D, Shin HS. Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking alpha1G-subunit of T-type calcium channels. Proc Natl Acad Sci U S A 2004;101:18195-9
19. Anderson MP, Mochizuki T, Xie J, et al. Thalamic Ca V 3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. Proc Natl Acad Sci U S A 2005;102:1743-8
20. Petrenko AB, Tsujita M, Kohno T, Sakimura K, Baba H. Mutation of alpha1G T-type calcium channels in mice does not change anesthetic requirements for loss of the righting reflex and minimum alveolar concentration but delays the onset of anesthetic induction. Anesthesiology 2007;106:1177-85
21. Lee J, Shin HS. T-type calcium channels and thalamocortical rhythms in sleep: a perspective from studies of T-type calcium channel knockout mice. CNS Neurol Disord Drug Targets 2007;6:63-9
22. Astori S, Wimmer RD, Prosser HM, et al. The Ca V 3.3 calcium channel is the major sleep spindle pacemaker in thalamus. Proc Natl Acad Sci U S A 2011;108:13823-8
23. Weiergraber M, Kamp MA, Radhakrishnan K, Hescheler J, Schneider T. The Ca V 2.3 voltage-gated calcium channel in epileptogenesis- shedding new light on an enigmatic channel. Neurosci Biobehav Rev 2006;30:1122-44
24. Weiergraber M, Henry M, Ho MS, Struck H, Hescheler J, Schneider T. Altered thalamocortical rhythmicity in Ca V 2.3-deficient mice. Mol Cell Neurosci 2008;39:605-18
25. Zaman T, Lee K, Park C, et al. Ca V 2.3 channels are critical for oscillatory burst discharges in the reticular thalamus and absence epilepsy. Neuron 2011;70:95-108
26. Weiergraber M, Henry M, Krieger A, et al. Altered seizure susceptibility in mice lacking the Ca V 2.3 E-type Ca2+ channel. Epilepsia 2006;47:839-50
27. Wilson SM, Toth PT, Oh SB, et al. The status of voltage-dependent calcium channels in alpha1E knock-out mice. J Neurosci 2000;20:8566-71
28. Weiergraber M, Henry M, Hescheler J, Smyth N, Schneider T. Electrocorticographic and deep intracerebral EEG recording in mice using a telemetry system. Brain Res Brain Res Protoc 2005;14:154-64
29. Kramer K, Kinter LB. Evaluation and applications of radiotelemetry in small laboratory animals. Physiol Genomics 2003;13:197-205
30. Patti CL, Zanin KA, Sanday L, et al. Effects of sleep deprivation on memory in mice: role of state-dependent learning. Sleep 2010;33:1669-79
31. Muller R, Struck H, Ho MS, et al. Atropine-sensitive hippocampal theta oscillations are mediated by Ca V 2.3 R-type Ca2+ channels. Neuroscience 2012;205:125-39
32. Kronland-Martinet R, Morlet J, Grossmann A. Analysis of soundpatterns through wavelet transforms. Int J Pattern Recognit Artif Intell 1987;1:273-302
33. Montgomery SM, Buzsaki G. Gamma oscillations dynamically couple hippocampal CA3 and CA1 regions during memory task performance. Proc Natl Acad Sci U S A 2007;104:14495-500
34. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008;3:1101-8
35. Weiergraber M, Henry M, Radhakrishnan K, Hescheler J, Schneider T. Hippocampal seizure resistance and reduced neuronal excitotoxicity in mice lacking the Ca V 2.3 E/R-type voltage-gated calcium channel. J Neurophysiol 2007;97:3660-9
36. Hara K, Harris RA. The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels. Anesth Analg 2002;94:313-8
37. Dalo NL, Hackman JC. The anesthetic urethane blocks excitatory amino acid responses but not GABA responses in isolated frog spinal cords. J Anesth 2013;27:98-103
38. Yasuda R, Sabatini BL, Svoboda K. Plasticity of calcium channels in dendritic spines. Nat Neurosci 2003;6:948-55
39. Bloodgood BL, Sabatini BL. Nonlinear regulation of unitary synaptic signals by Ca V 2.3 voltage-sensitive calcium channels located in dendritic spines. Neuron 2007;53:249-60
40. Takei T, Saegusa H, Zong S, Murakoshi T, Makita K, Tanabe T. Anesthetic sensitivities to propofol and halothane in mice lacking the R-type Ca V 2.3 Ca2+ channel. Anesth Analg 2003;97:96-103
41. Joksovic PM, Weiergraber M, Lee W, Struck H, Schneider T, Todorovic SM. Isoflurane-sensitive presynaptic R-type calcium channels contribute to inhibitory synaptic transmission in the rat thalamus. J Neurosci 2009;29:1434-45
42. Joksovic PM, Brimelow BC, Murbartian J, Perez-Reyes E, Todorovic SM. Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca V 3.3 channels. Br J Pharmacol 2005;144:59-70
43. Todorovic SM, Perez-Reyes E, Lingle CJ. Anticonvulsants but not general anesthetics have differential blocking effects on different T-type current variants. Mol Pharmacol 2000;58:98-108
44. Talley EM, Cribbs LL, Lee JH, Daud A, Perez-Reyes E, Bayliss DA. Differential distribution of three members of a gene family encoding low voltage-Activated (T-type) calcium channels.J Neurosci 1999;19:1895-911
45. Zhang Y, Mori M, Burgess DL, Noebels JL. Mutations in high-voltageactivated calcium channel genes stimulate low-voltage-Activated currents in mouse thalamic relay neurons. J Neurosci 2002;22:6362-71
46. Song I, Kim D, Choi S, Sun M, Kim Y, Shin HS. Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice. J Neurosci 2004;24:5249-57
47. Ernst WL, Noebels JL. Expanded alternative splice isoform profiling of the mouse Ca V 3.1/alpha1G T-type calcium channel. BMC Mol Biol 2009;10:53
48. Manning JP, Richards DA, Bowery NG. Pharmacology of absence epilepsy. Trends Pharmacol Sci 2003;24:542-9
49. Khosravani H, Zamponi GW. Voltage-gated calcium channels and idiopathic generalized epilepsies. Physiol Rev 2006;86:941-66
50. Deransart C, Vercueil L, Marescaux C, Depaulis A. The role of basal ganglia in the control of generalized absence seizures. Epilepsy Res 1998;32:213-23
51. Pace-Schott EF, Hobson JA. The neurobiology of sleep: genetics, cellular physiology and subcortical networks. Nat Rev Neurosci 2002;3:591-605
52. Merica H, Fortune RD. The neuronal transition probability (NTP) model for the dynamic progression of non-REM sleep EEG: the role of the suprachiasmatic nucleus. PLoS One 2011;6:e23593
53. Wurts SW, Edgar DM. Circadian and homeostatic control of rapid eye movement (REM) sleep: promotion of REM tendency by the suprachiasmatic nucleus. J Neurosci 2000;20:4300-10
54. Cloues RK, Sather WA. Afterhyperpolarization regulates firing rate in neurons of the suprachiasmatic nucleus. J Neurosci 2003;23:1593-604
55. Pierson PM, Liu X, Raggenbass M. Suppression of potassium channels elicits calcium-dependent plateau potentials in suprachiasmatic neurons of the rat. Brain Res 2005;1036:50-9
56. Jha SK, Ross RJ, Morrison AR. Sleep-related neurons in the central nucleus of the amygdala of rats and their modulation by the dorsal raphe nucleus. Physiol Behav 2005;86:415-26
57. Lee SC, Choi S, Lee T, Kim HL, Chin H, Shin HS. Molecular basis of R-type calcium channels in central amygdala neurons of the mouse. Proc Natl Acad Sci U S A 2002;99:3276-81
58. Weiergräber M, Henry M, Südkamp M, de Vivie ER, Hescheler J, Schneider T. Ablation of Ca V 2.3 /E-type voltage-gated calcium channel results in cardiac arrhythmia and altered autonomic control within the murine cardiovascular system. Basic Res Cardiol 2005;100:1-13
59. Chen CC, Lamping KG, Nuno DW, et al. Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels. Science 2003;21;302:1416-8.