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Volumn 9, Issue 6, 2014, Pages 2166-2172

Autophagy in human articular chondrocytes is cytoprotective following glucocorticoid stimulation

Author keywords

Apoptosis; Autophagy; Chondrocytes; Dexamethasone; Glucocorticoid

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; RAPAMYCIN;

EID: 84899689924     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2102     Document Type: Article
Times cited : (33)

References (43)
  • 1
    • 0031857481 scopus 로고    scopus 로고
    • An update on the epidemiology of knee and hip osteoarthritis with a view to prevention
    • DOI 10.1002/1529-0131(199808)41:8<1343::AID-ART3
    • Felson DT and Zhang Y: An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum 41: 1343-1355, 1998. (Pubitemid 28373113)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.8 , pp. 1343-1355
    • Felson, D.T.1    Zhang, Y.2
  • 2
    • 1842833389 scopus 로고    scopus 로고
    • Corticosteroid treatment of experimental arthritis retards cartilage destruction as determined by histology and serum COMP
    • DOI 10.1093/rheumatology/keh073
    • Larsson E, Erlandsson Harris H, Larsson A, Månsson B, Saxne T and Klareskog L: Corticosteroid treatment of experimental arthritis retards cartilage destruction as determined by histology and serum COMP. Rheumatology (Oxford) 43: 428-434, 2004. (Pubitemid 38489358)
    • (2004) Rheumatology , vol.43 , Issue.4 , pp. 428-434
    • Larsson, E.1    Harris, H.E.2    Larsson, A.3    Mansson, B.4    Saxne, T.5    Klareskog, L.6
  • 3
    • 0001582959 scopus 로고
    • Intra-articular hydrocortisone in arthritis and allied conditions; a summary of two years' clinical experience
    • Hollander JL: Intra-articular hydrocortisone in arthritis and allied conditions; a summary of two years' clinical experience. J Bone Joint Surg Am 35-A: 983-990, 1953.
    • (1953) J Bone Joint Surg Am , vol.35 A , pp. 983-990
    • Hollander, J.L.1
  • 4
    • 0023875926 scopus 로고
    • Intra-articular injection for pain relief in patients awaiting hip replacement
    • Flanagan J, Casale FF, Thomas TL and Desai KB: Intra-articular injection for pain relief in patients awaiting hip replacement. Ann R Coll Surg Engl 70: 156-157, 1988.
    • (1988) Ann R Coll Surg Engl , vol.70 , pp. 156-157
    • Flanagan, J.1    Casale, F.F.2    Thomas, T.L.3    Desai, K.B.4
  • 5
    • 0019192332 scopus 로고
    • The efficacy of intraarticular steroids in osteoarthritis: A double-blind study
    • Friedman DM and Moore ME: The efficacy of intraarticular steroids in osteoarthritis: a double-blind study. J Rheumatol 7: 850-856, 1980. (Pubitemid 11181502)
    • (1980) Journal of Rheumatology , vol.7 , Issue.6 , pp. 850-856
    • Friedman, D.M.1    Moore, M.E.2
  • 7
    • 0023130086 scopus 로고
    • Effects of dexamethasone on the growth of cultured rabbit articular chondrocytes: Relation with the nuclear glucocorticoid-receptor complex
    • Hainque B, Dominice J, Jaffray P, Ronot X and Adolphe M: Effects of dexamethasone on the growth of cultured rabbit articular chondrocytes: relation with the nuclear glucocorticoid-recepter complex. Ann Rheum Dis 46: 146-152, 1987. (Pubitemid 17015720)
    • (1987) Annals of the Rheumatic Diseases , vol.46 , Issue.2 , pp. 146-152
    • Hainque, B.1    Dominice, J.2    Jaffray, P.3
  • 8
    • 0033638543 scopus 로고    scopus 로고
    • Apoptosis in normal and osteoarthritic human articular cartilage
    • Héraud F, Héraud A and Harmand MF: Apoptosis in normal and osteoarthritic human articular cartilage. Ann Rheum Dis 59: 959-965, 2000.
    • (2000) Ann Rheum Dis , vol.59 , pp. 959-965
    • Héraud, F.1    Héraud, A.2    Harmand, M.F.3
  • 9
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • DOI 10.1038/nature06639, PII NATURE06639
    • Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008. (Pubitemid 351317450)
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 10
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B and Kroemer G: Autophagy in the pathogenesis of disease. Cell 132: 27-42, 2008.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 11
    • 66949165559 scopus 로고    scopus 로고
    • Autophagy in disease: A double-edged sword with therapeutic potential
    • Lond
    • Martinet W, Agostinis P, Vanhoecke B, Dewaele M and De Meyer GR: Autophagy in disease: a double-edged sword with therapeutic potential. Clin Sci (Lond) 116: 697-712, 2009.
    • (2009) Clin Sci , vol.116 , pp. 697-712
    • Martinet, W.1    Agostinis, P.2    Vanhoecke, B.3    Dewaele, M.4    De Meyer, G.R.5
  • 12
    • 77649128750 scopus 로고    scopus 로고
    • Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis
    • Caramés B, Taniguchi N, Otsuki S, Blanco FJ and Lotz M: Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis. Arthritis Rheum 62: 791-801, 2010.
    • (2010) Arthritis Rheum , vol.62 , pp. 791-801
    • Caramés, B.1    Taniguchi, N.2    Otsuki, S.3    Blanco, F.J.4    Lotz, M.5
  • 14
    • 0033534734 scopus 로고    scopus 로고
    • Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells
    • DOI 10.1074/jbc.274.2.1058
    • Shigemitsu K, Tsujishita Y, Hara K, Nanahoshi M, Avruch J and Yonezawa K: Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells. J Biol Chem 274: 1058-1065, 1999. (Pubitemid 29058080)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.2 , pp. 1058-1065
    • Shigemitsu, K.1    Tsujishita, Y.2    Hara, K.3    Nanahoshi, M.4    Avruch, J.5    Yonezawa, K.6
  • 15
    • 0033573016 scopus 로고    scopus 로고
    • The TOR signaling cascade regulates gene expression in response to nutrients
    • DOI 10.1101/gad.13.24.3271
    • Cardenas ME, Cutler NS, Lorenz MC, Di Como CJ and Heitman J: The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13: 3271-3279, 1999. (Pubitemid 30030448)
    • (1999) Genes and Development , vol.13 , Issue.24 , pp. 3271-3279
    • Cardenas, M.E.1    Cutler, N.S.2    Lorenz, M.C.3    Di, C.C.J.4    Heitman, J.5
  • 16
    • 34249679614 scopus 로고    scopus 로고
    • mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer
    • DOI 10.1016/j.molmed.2007.04.002, PII S1471491407000664
    • Dann SG, Selvaraj A and Thomas G: mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer. Trends Mol Med 13: 252-259, 2007. (Pubitemid 46836871)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.6 , pp. 252-259
    • Dann, S.G.1    Selvaraj, A.2    Thomas, G.3
  • 18
    • 70349750492 scopus 로고    scopus 로고
    • Rapamycin protects against rotenone-induced apoptosis through autophagy induction
    • Pan T, Rawal P, Wu Y, Xie W, Jankovic J and Le W: Rapamycin protects against rotenone-induced apoptosis through autophagy induction. Neuroscience 164: 541-551, 2009.
    • (2009) Neuroscience , vol.164 , pp. 541-551
    • Pan, T.1    Rawal, P.2    Wu, Y.3    Xie, W.4    Jankovic, J.5    Le, W.6
  • 20
    • 84872197194 scopus 로고    scopus 로고
    • Gluococorticoid could influence extracellular matrix synthesis through Sox9 via p38 MAPK pathway
    • Song YW, Zhang T and Wang WB: Gluococorticoid could influence extracellular matrix synthesis through Sox9 via p38 MAPK pathway. Rheumatol Int 32: 3669-3673, 2012.
    • (2012) Rheumatol Int , vol.32 , pp. 3669-3673
    • Song, Y.W.1    Zhang, T.2    Wang, W.B.3
  • 23
    • 84869187913 scopus 로고    scopus 로고
    • Management of primary knee osteoarthritis and indications for total knee arthroplasty for general practitioners
    • Van Manen MD, Nace J and Mont MA: Management of primary knee osteoarthritis and indications for total knee arthroplasty for general practitioners. J Am Osteopath Assoc 112: 709-715, 2012.
    • (2012) J Am Osteopath Assoc , vol.112 , pp. 709-715
    • Van Manen, M.D.1    Nace, J.2    Mont, M.A.3
  • 24
    • 27644499322 scopus 로고    scopus 로고
    • Injectable corticosteroids in treatment of arthritis of the knee
    • DOI 10.1016/j.amjmed.2005.05.003, PII S0002934305003529
    • Schumacher HR and Chen LX: Injectable corticosteroids in treatment of arthritis of the knee. Am J Med 118: 1208-1214, 2005. (Pubitemid 41573603)
    • (2005) American Journal of Medicine , vol.118 , Issue.11 , pp. 1208-1214
    • Schumacher, H.R.1    Chen, L.X.2
  • 25
    • 33751531514 scopus 로고    scopus 로고
    • Short-term efficacy of pharmacotherapeutic interventions in osteoarthritic knee pain: A meta-analysis of randomised placebo-controlled trials
    • DOI 10.1016/j.ejpain.2006.02.013, PII S1090380106000528
    • Bjordal JM, Klovning A, Ljunggren AE and Slørdal L: Short-term efficacy of pharmacotherapeutic interventions in osteoarthritic knee pain: A meta-analysis of randomised placebo-controlled trials. Eur J Pain 11: 125-138, 2007. (Pubitemid 44829965)
    • (2007) European Journal of Pain , vol.11 , Issue.2 , pp. 125-138
    • Bjordal, J.M.1    Klovning, A.2    Ljunggren, A.E.3    Slordal, L.4
  • 26
    • 73649111416 scopus 로고    scopus 로고
    • Mechanisms of impaired growth: Effect of steroids on bone and cartilage
    • Olney RC: Mechanisms of impaired growth: effect of steroids on bone and cartilage. Horm Res 72 (Suppl 1): 30-35, 2009.
    • (2009) Horm Res , vol.72 , Issue.SUPPL. 1 , pp. 30-35
    • Olney, R.C.1
  • 28
    • 77957708503 scopus 로고    scopus 로고
    • Increased chondrocyte death after steroid and local anesthetic combination
    • Farkas B, Kvell K, Czömpöly T, Illés T and Bárdos T: Increased chondrocyte death after steroid and local anesthetic combination. Clin Orthop Relat Res 468: 3112-3120, 2010.
    • (2010) Clin Orthop Relat Res , vol.468 , pp. 3112-3120
    • Farkas, B.1    Kvell, K.2    Czömpöly, T.3    Illés, T.4    Bárdos, T.5
  • 29
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • DOI 10.1038/sj.onc.1207521
    • Gozuacik D and Kimchi A: Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23: 2891-2906, 2004. (Pubitemid 38638851)
    • (2004) Oncogene , vol.23 , Issue.16 REV. ISS. 2 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 30
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • He C and Klionsky DJ: Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 43: 67-93, 2009.
    • (2009) Annu Rev Genet , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 32
    • 10644271561 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in osteoarthritis
    • DOI 10.1016/j.mito.2004.07.022, PII S1567724904001606
    • Blanco FJ, López-Armada MJ and Maneiro E: Mitochondrial dysfunction in osteoarthritis. Mitochondrion 4: 715-728, 2004. (Pubitemid 39646817)
    • (2004) Mitochondrion , vol.4 , Issue.5-6 SPEC. ISS. , pp. 715-728
    • Blanco, F.J.1    Lopez-Armada, M.J.2    Maneiro, E.3
  • 33
    • 0035988302 scopus 로고    scopus 로고
    • Role of chondrocyte death and hypocellularity in ageing human articular cartilage and the pathogenesis of osteoarthritis
    • Mobasheri A: Role of chondrocyte death and hypocellularity in ageing human articular cartilage and the pathogenesis of osteoarthritis. Med Hypotheses 58: 193-197, 2002.
    • (2002) Med Hypotheses , vol.58 , pp. 193-197
    • Mobasheri, A.1
  • 34
    • 3142722961 scopus 로고    scopus 로고
    • Chondroptosis: A variant of apoptotic cell death in chondrocytes?
    • DOI 10.1023/B:APPT.0000025803.17498.26
    • Roach HI, Aigner T and Kouri JB: Chondroptosis: a variant of apoptotic cell death in chondrocytes? Apoptosis 9: 265-277, 2004. (Pubitemid 38981501)
    • (2004) Apoptosis , vol.9 , Issue.3 , pp. 265-277
    • Roach, H.I.1    Aigner, T.2    Kouri, J.B.3
  • 37
    • 77951666929 scopus 로고    scopus 로고
    • Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model
    • Almonte-Becerril M, Navarro-Garcia F, Gonzalez-Robles A, Vega-Lopez MA, Lavalle C and Kouri JB: Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model. Apoptosis 15: 631-638, 2010.
    • (2010) Apoptosis , vol.15 , pp. 631-638
    • Almonte-Becerril, M.1    Navarro-Garcia, F.2    Gonzalez-Robles, A.3    Vega-Lopez, M.A.4    Lavalle, C.5    Kouri, J.B.6
  • 38
    • 2442463314 scopus 로고    scopus 로고
    • Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin
    • DOI 10.1097/00075197-200401000-00008
    • Kimball SR and Jefferson LS: Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin. Curr Opin Clin Nutr Metab Care 7: 39-44, 2004. (Pubitemid 40348182)
    • (2004) Current Opinion in Clinical Nutrition and Metabolic Care , vol.7 , Issue.1 , pp. 39-44
    • Kimball, S.R.1    Jefferson, L.S.2
  • 39
    • 66849131401 scopus 로고    scopus 로고
    • Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling
    • Kim MS, Wu KY, Auyeung V, Chen Q, Gruppuso PA and Phornphutkul C: Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling. Am J Physiol Endocrinol Metab 296: E1374-E1382, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Kim, M.S.1    Wu, K.Y.2    Auyeung, V.3    Chen, Q.4    Gruppuso, P.A.5    Phornphutkul, C.6
  • 40
    • 84872710561 scopus 로고    scopus 로고
    • Vertical inhibition of the PI3K/Akt/mTOR pathway for the treatment of osteoarthritis
    • Chen J, Crawford R and Xiao Y: Vertical inhibition of the PI3K/Akt/mTOR pathway for the treatment of osteoarthritis. J Cell Biochem 114: 245-249, 2013.
    • (2013) J Cell Biochem , vol.114 , pp. 245-249
    • Chen, J.1    Crawford, R.2    Xiao, Y.3
  • 42
    • 0032053962 scopus 로고    scopus 로고
    • Interleukin-1beta induction of c-fos and collagenase expression in articular chondrocytes: Involvement of reactive oxygen species
    • DOI 10.1002/(SICI)1097-4644(19980401)69:1<19::AID
    • Lo YY, Conquer JA, Grinstein S and Cruz TF: Interleukin-1 beta induction of c-fos and collagenase expression in articular chondrocytes: involvement of reactive oxygen species. J Cell Biochem 69: 19-29, 1998. (Pubitemid 28099919)
    • (1998) Journal of Cellular Biochemistry , vol.69 , Issue.1 , pp. 19-29
    • Lo, Y.Y.C.1    Conquer, J.A.2    Grinstein, S.3    Cruz, T.F.4
  • 43
    • 0141504018 scopus 로고    scopus 로고
    • The role of reactive oxygen species in homeostasis and degradation of cartilage
    • DOI 10.1016/S1063-4584(03)00150-X
    • Henrotin YE, Bruckner P and Pujol JP: The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage 11: 747-755, 2003. (Pubitemid 37184493)
    • (2003) Osteoarthritis and Cartilage , vol.11 , Issue.10 , pp. 747-755
    • Henrotin, Y.E.1    Bruckner, P.2    Pujol, J.-P.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.