Enzyme, β-galactosidase immobilized on membrane surface for galacto-oligosaccharides formation from lactose: Kinetic study with feed flow under recirculation loop

Biochemical Engineering Journal

Volumn 88, Issue , 2014, Pages 68-76

  Palai, Tapas ^a   Singh, Avaneesh K ^a   Bhattacharya, Prashant K ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

Author keywords

Galacto oligosaccharides; Immobilized enzymes; Kinetic parameters; Lactose; Microporous membrane; Modeling

Indexed keywords

COMPUTER SIMULATION; DIGITAL STORAGE; ENZYMES; FLOW RATE; KINETIC PARAMETERS; MEMBRANES; MICROPOROSITY; MODELS; OLIGOSACCHARIDES; SYNTHESIS (CHEMICAL);

ENZYMATIC REACTION; GALACTO-OLIGOSACCHARIDES; IMMOBILIZED ENZYME; IMMOBILIZED MEMBRANES; LACTOSE; MICRO POROUS MEMBRANES; POLYVINYLIDENE FLUORIDE MEMBRANES; RE-CIRCULATION LOOPS;

LOADING;

BETA GALACTOSIDASE; GALACTOSE OLIGOSACCHARIDE; GLUTARALDEHYDE; IMMOBILIZED ENZYME; LACTOSE; POLYVINYLIDENE FLUORIDE;

ARTICLE; CROSS LINKING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME IMMOBILIZATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REACTION TIME; SURFACE PROPERTY;

EID: 84899680782     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2014.03.017     Document Type: Article

References (43)

1. Rios G.M., Belleville M.P., Paolucci D., Sanchez J. Progress in enzymatic membrane reactors - a review. J. Membr. Sci. 2004, 242:189-196.
2. Albayrak N., Yang S.T. Production of galacto-oligosaccharides from lactose by Aspergillus oryzae β-galactosidase immobilized on cotton cloth. Biotechnol. Bioeng. 2002, 77:8-19.
3. Giorno L., Drioli E. Biocatalytic membrane reactors: applications and perspectives. Trends Biotechnol. 2000, 18:339-349.
4. Palai T., Bhattacharya P.K. Kinetics of lactose conversion to galacto-oligosaccharides by β-galactosidase immobilized on PVDF membrane. J. Biosci. Bioeng. 2013, 115:668-673.
5. Shin H.-J., Park J.-M., Yang J.-W. Continuous production of galacto-oligosaccharides from lactose by Bullera singularis β-galactosidase immobilized in chitosan beads. Process Biochem. 1998, 33:787-792.
6. Nakkharat P., Haltrich D. β-Galactosidase from Talaromyces thermophilus immobilized on to Eupergit C for production of galacto-oligosaccharides during lactose hydrolysis in batch and packed-bed reactor. World J. Microbiol. Biotechnol. 2007, 23:759-764.
7. Ansari S.A., Husain Q. Lactose hydrolysis by β-galactosidase immobilized on concanavalin A-cellulose in batch and continuous mode. J. Mol. Catal. B: Enzym. 2010, 63:68-74.
8. Czermak P., Ebrahimi M., Grau K., Netz S., Sawatzki G., Pfromm P.H. Membrane-assisted enzymatic production of galactosyl-oligosaccharides from lactose in a continuous process. J. Membr. Sci. 2004, 232:85-91.
9. Axelsson A., Zacch G. Economic evaluation of the hydrolysis of lactose using immobilized β-galactosidase. Appl. Biochem. Biotechnol. 1990, 24/25:679-693.
10. Panesar P.S., Panesar R., Singh R.S., Kennedy J.F., Kumar H. Microbial production, immobilization and applications of β-d-galactosidase. J. Chem. Technol. Biotechnol. 2006, 81:530-543.
11. Gaur R., Pant H., Jain R., Khare S.K. Galacto-oligosaccharide synthesis by immobilized Aspergillus oryzae β-galactosidase. Food Chem. 2006, 97:426-430.
12. Mozaffar Z., Nakanishi K., Matsuno R. Continuous production of galacto-oligosaccharides from lactose using immobilized β-galactosidase from Bacillus circulans. Appl. Microbiol. Biotechnol. 1986, 25:224-228.
13. Berger J.L., Lee B.H., Lacroix C. Oligosaccharide synthesis by free and immobilized β-galactosidases from Thermus aquaticus YT-1. Biotechnol. Lett. 1995, 17:1077-1080.
14. Urrutia P., Mateo C., Guisan J.M., Wilson L., Illanes A. Immobilization of Bacillus circulans β-galactosidase and its application in the synthesis of galacto-oligosaccharides under repeated-batch operation. Biochem. Eng. J. 2013, 77:41-48.
15. Zhou Q.Z.K., Chen X.D. Immobilization of β-galactosidase on graphite surface by glutaraldehyde. J. Food Eng. 2001, 48:69-74.
16. Ebrahimi M., Engel L., Peter S., Grau K., Czermak P. Membrane supported enzymatic synthesis of galactosyl-oligosaccharides. Desalination 2006, 200:509-510.
17. Leiva M.H.L., Guzman M. Formation of oligosaccharides during enzymatic hydrolysis of milk whey permeates. Process Biochem. 1995, 30:757-762.
18. Souza R.R.d., Bergamasco R., Costa S.C.d., Feng X., Faria S.H.B., Gimenes M.L. Recovery and purification of lactose from whey. Chem. Eng. Process 2010, 49:1137-1143.
19. Sen D., Sarkar A., Gosling A., Gras S.L., Stevens G.W., Kentish S.E., Bhattacharya P.K., Barber A.R., Bhattacharjee C. Feasibility study of enzyme immobilization on polymeric membrane: a case study with enzymatically galacto-oligosaccharides production from lactose. J. Membr. Sci. 2011, 378:471-478.
20. Sako T., Matsumoto K., Tanaka R. Recent progress on research and applications of non-digestible galacto-oligosaccharides. Int. Dairy J. 1999, 9:69-80.
21. Gosling A., Alftre'n J., Stevens G.W., Barber A.R., Kentish S.E., Gras S.L. Facile pretreatment of Bacillus circulans β-galactosidase increases the yield of galactosyl oligosaccharides in milk and lactose reaction systems. J. Agric. Food Chem. 2009, 30:11570-11574.
22. Neri D.F.M., Balcão V.M., Dourado F.O.Q., Oliveirad J.M.B., Carvalho L.B., Teixeira J.A. Immobilized β-galactosidase onto magnetic particles coated with polyaniline: support characterization and galactooligosaccharides production. J. Mol. Catal. B: Enzym. 2011, 70:74-80.
23. Sen D., Sarkar A., Das S., Chowdhury R., Bhattacharjee C. Batch hydrolysis and rotating disk membrane bioreactor for the production of galacto-oligosaccharides: a comparative study. Ind. Eng. Chem. Res. 2012, 51:10671-10681.
24. Das R., Sen D., Sarkar A., Bhattacharyya S., Bhattacharjee C. A comparative study on the production of galacto-oligosaccharide from whey permeate in recycle membrane reactor and in enzymatic batch reactor. Ind. Eng. Chem. Res. 2011, 50:806-816.
25. Mahoney R.R. Galactosyl-oligosaccharide formation during lactose hydrolysis: a review. Food Chem. 1998, 63:147-154.
26. Sen D., Gosling A., Stevens G.W., Bhattacharya P.K., Barber A.R., Kentish S.E., Bhattacharjee C., Gras S.L. Galactosyl oligosaccharide purification by ethanol precipitation. Food Chem. 2011, 128:773-777.
27. Goulas A.K., Kapasakalidis P.G., Sinclair H.R., Rastall R.A., Grandison A.S. Purification of oligosaccharides by nanofiltration. J. Membr. Sci. 2002, 209:321-335.
28. Gosling A., Stevens G.W., Barber A.R., Kentish S.E., Gras S.L. Recent advances refining galactooligosaccharide production from lactose. Food Chem. 2009, 121:307-318.
29. Boon M.A., Janssen A.E.M., Padt A.v.d. Modelling and parameter estimation of the enzymatic synthesis of oligosaccharides by β-galactosidase from Bacillus circulans. Biotechnol. Bioeng. 1999, 64:558-567.
30. Chen C.W., Yang C.C.O., Yeh C.W. Synthesis of galactooligosaccharides and transgalactosylation modeling in reverse micelles. Enzyme Microb. Technol. 2003, 33:497-507.
31. Bruins M.E., Strubel M., Lieshout J.F.T.v., Janssen A.E.M., Boom R.M. Oligosaccharide synthesis by the hyperthermostable β-glucosidase from Pyrococcus furiosus: kinetics and modelling. Enzyme Microb. Technol. 2003, 33:3-11.
32. Palai T., Mitra S., Bhattacharya P.K. Kinetics and design relation for enzymatic conversion of lactose into galacto-oligosaccharides using commercial grade β-galactosidase. J. Biosci. Bioeng. 2012, 114:418-423.
33. Agrahari G.K., Verma N., Bhattacharya P.K. Application of hollow fiber membrane contactor for the removal of carbon dioxide from water under liquid-liquid extraction mode. J. Membr. Sci. 2011, 375:323-333.
34. Palai T., Kumar A., Bhattacharya P.K. Synthesis and characterization of thermo-responsive poly-N-isopropylacrylamide bioconjugates for application in the formation of galacto-oligosaccharides. Enzyme Microb. Technol. 2014, 55:40-49.
35. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fugimoto E.K., Goeke N.M., Olson B.J., Klenk D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 1985, 150:76-85.
36. Bhattacharjee C., Bhattacharya P.K. Prediction of limiting flux in ultrafiltration of kraft black liquor. J. Membr. Sci. 1992, 72:137-147.
37. Kuo C.-H., Chen G.-J., Twu Y.-K., Liu Y.-C., Shieh C.-J. Optimum lipase immobilized on diamine-grafted PVDF membrane and its characterization. Ind. Eng. Chem. Res. 2012, 51:5141-5147.
38. Cadena P.G., Jeronimo R.A.S., Melo J.M., Silva R.A., Filho J.L.L., Pimentel M.C.B. Covalent immobilization of invertase on polyurethane, plast-film and ferromagnetic Dacron. Bioresour. Technol. 2010, 101:1595-1602.
39. Prenosil J.E., Stuker E., Bourne J.R. Formation of oligosaccharides during enzymatic lactose: Part I: State of the art. Biotechnol. Bioeng. 1987, 30:1019-1025.
40. Bayramoglu G., Tunali Y., Arica M.Y. Immobilization of β-galactosidase onto magnetic poly(GMA-MMA) beads for hydrolysis of lactose in bed reactor. Catal. Commun. 2007, 8:1094-1101.
41. Shakya A.K., Sharma P., Kumar A. Synthesis and characterization of thermo-responsive poly(N-isopropylacrylamide)-bovine liver catalase bioconjugate. Enzyme Microb. Technol. 2010, 47:277-282.
42. Ozdural A.R., Tanyolac D., Demircan Z., Boyaci I.H., Mutlu M., Webb C. A new method for determination of apparent kinetics parameters in recirculating packed-bed immobilized enzyme reactors. Chem. Eng. Sci. 2001, 56:3483-3490.
43. Hoops S., Sahle S., Gauges R., Lee C., Pahle J., Simus N., Singhal M., Xu L., Mendes P., Kummer U. COPASI - a complex pathway simulator. Bioinformatics 2006, 22:3067-3074.