Long-chain n-3 DHA reduces the extent of skeletal muscle fatigue in the rat in vivo hindlimb model

British Journal of Nutrition

Volumn 111, Issue 6, 2014, Pages 996-1003

  Peoples, Gregory E ^a   McLennan, Peter L ^b  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

DHA; Fatigue; Fish oil; Oxygen consumption

Indexed keywords

CERVONIC ACID; FISH OIL; GLUCOSE; GLYCOGEN; LACTIC ACID; OMEGA 3 FATTY ACID; SATURATED FATTY ACID; DOCOSAHEXAENOIC ACID; EDIBLE OIL; OMEGA 6 FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL OXYGEN TENSION; ARTERY BLOOD FLOW; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIETARY INTAKE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; GLYCOGEN MUSCLE LEVEL; HINDLIMB; IN VIVO STUDY; LACTATE BLOOD LEVEL; LIMB PERFUSION; MALE; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE FIBER MEMBRANE; MUSCLE STRESS; MUSCLE TONE; NONHUMAN; OXYGEN CONSUMPTION; PLANTARIS MUSCLE; RAT; SCIATIC NERVE; SKELETAL MUSCLE OXYGEN CONSUMPTION; SOLEUS MUSCLE; THERAPY EFFECT; WISTAR RAT; ANIMAL; BLOOD; CHEMISTRY; DIET; DRUG EFFECT; PHYSIOLOGY; SKELETAL MUSCLE;

MAMMALIA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; BLOOD GLUCOSE; DIET; DIETARY FATS, UNSATURATED; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FISH OILS; GLYCOGEN; HINDLIMB; LACTIC ACID; MALE; MUSCLE FATIGUE; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; RATS; RATS, WISTAR;

EID: 84899671361     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114513003449     Document Type: Article

References (45)

1. Barclay JK (1993) A delivery-independent blood flow effect on skeletal muscle fatigue. J Appl Physiol 74, 2294-2300.
2. Gladden LB, McIntosh BR & Stainsby WN (1978) Oxygen uptake and developed tension during and after fatigue, curare block, and ischemia. J Appl Physiol 45, 751-756.
3. 2 tension and vascular resistance in contracting canine skeletal muscle. J Appl Physiol 65, 1075-1081.
4. 2 in regulating tissue respiration in dog muscle working in situ. J Appl Physiol 73, 728-736.
5. 2 delivery on intracellular homeostasis in contracting skeletal muscle. J Appl Physiol 80, 1313-1321.
6. Gorjao R, Azevedo-Martins A, Rodrigues H, et al. (2009) Comparative effects of DHA and EPA on cell function. Pharmacol Ther 122, 56-64.
7. McLennan P, Howe P, Abeywardena M, et al. (1996) The cardiovascular protective role of docosahexaenoic acid. Eur J Pharmacol 300, 83-89.
8. McLennan P, Abeywardena MY & Charnock JS (1988) Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion. Am Heart J 116, 709-717.
9. Pepe S & McLennan PL (1996) Dietary fish oil confers direct antiarrhythmic properties on the myocardium of rats. J Nutr 126, 34-42.
10. Charnock JS, Abeywardena MY, Poletti VM, et al. (1992) Differences in fatty acid composition of various tissues of the marmoset monkey after different lipids supplement diets. Comp Biochem Physiol 101A, 387-393.
11. McLennan PL, Bridle TM & Abeywardena MY (1992) Dietary lipid modulation of ventricular fibrillation threshold in the marmoset monkey. Am Heart J 123, 1555-1561.
12. Pan D & Storlien LH (1993) Dietary lipid profile is a determinate of tissue phospholipids fatty acid composition and rate weight gain in rats. J Nutr 123, 512-519.
13. Ayre K & Hulbert A (1996) Dietary fatty acid profile influences the composition of skeletal muscle phospholipids in rats. J Nutr 126, 653-662.
14. Peoples G & McLennan P (2010) Dietary fish oil reduces skeletal muscle oxygen consumption, provides fatigue resistance and improves contractile recovery in the rat in vivo hindlimb. Br J Nutr 104, 1771-1779.
15. Clavel S, Farout L, Briand M, et al. (2002) Effect of endurance training and/or fish oil supplemented diet on cytoplasmic fatty acid binding protein in rat skeletal muscles and heart. Eur J Appl Physiol 87, 193-201.
16. Kamolrat T, Gray S & Thivierge M (2012) Fish oil positively regulates anabolic signalling alongside an increase in whole-body gluconeogenesis in ageing skeletal muscle. Eur J Nutr 52, 647-657.
17. Peoples G, McLennan P, Howe P, et al. (2008) Fish oil reduces heart rate and oxygen consumption during exercise. J Cardiovasc Pharmacol 52, 540-547.
18. Peoples G, Hoy A, Henry R, et al. (2013) Autologous pumpperfused rat hindlimb preparation for investigating muscle function and metabolism in vivo. Microcirculation 20, 511-523.
19. Buckley J, Burgess S, Murphy K, et al. (2009) DHA-rich fish oil lowers heart rate during submaximal exercise in elite Australian Rules footballers. J Sci Med Sport 12, 503-507.
20. Oostenburg GS, Mensink RP, Hardeman MR, et al. (1997) Exercise performance, red blood cell deformability, and lipid peroxidation: effects of fish oil and vitamin E. J Appl Physiol 83, 746-752.
21. Raastad T, Hostmark AT & Stromme SB (1997) Omega-3 fatty acid supplementation does not improve maximal aerobic power, anaerobic threshold and running performance in well trained soccer players. Scand J Med Sci Sports 7, 25-31.
22. Mickleborough T (2013) Omega-3 polyunsaturated fatty acids in physical performance optimisation. Int J Sport Nutr Exerc Metab 23, 83-96.
23. Hoy A, Peoples G & McLennan P (2009) The effect of vasoconstrictors on oxygen consumption in resting and contracting skeletal muscle of the autologous pump-perfused rate hindlimb. J Physiol Pharmacol 60, 155-160.
24. Reeves P, Nielsen F & Fahey G (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951.
25. Owen A, Peter-Przyborowska B, Hoy A, et al. (2004) Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition. Lipids 39, 955-961.
26. Hogan MC, Gladden LB, Grassi B, et al. (1998) Bioenergetics of contracting skeletal muscle after partial reduction of blood flow. J Appl Physiol 84, 1882-1888.
27. Stainsby WN & Renkin EM (1961) Autoregulation of blood flow in resting skeletal muscle. Am J Physiol 201, 117-122.
28. Pepe S & McLennan PL (2002) Cardiac membrane fatty acid composition modulates myocardial oxygen consumption and postischemic recovery of contractile function. Circulation 105, 2303-2308.
29. Fitts RH (1994) Cellular mechanisms of muscle fatigue. Physiol Rev 74, 49-74.
30. 31P-NMR. Muscle Nerve 17, 1002-1009.
31. Allen D, Lamb G & Westerblab H (2008) Skeletal muscle fatigue: cellular mechanisms. Physiol Rev 88, 287-332.
32. 2+ release and muscle fatigue. J Appl Physiol 87, 471-483.
33. Verberg E, Thorud H, Eriksen M, et al. (2001) Muscle contractile properties during intermittent nontetanic stimulation in rat skeletal muscle. Am J Physiol Regul Integr Comp Physiol 281, R1952-R1965.
34. McLennan P & Abeywardena MY (2005) Membrane basis for fish oil effects on the heart: linking natural hibernators to prevention of human sudden cardiac death. J Membr Biol 206, 85-102.
35. 2+ activation of PDH. Am J Physiol 276, H149-H158.
36. Abdukeyum G, Owen A & McLennan P (2008) Dietary (n-3) long chain polyunsaturated fatty acids inhibit ischemia and reperfusion arrhythmias and infarction in rat heart not enhanced by ischemic preconditioning. J Nutr 138, 1902-1909.
37. Stainsby WN & Welch HG (1966) Lactate metabolism of contracting dog skeletal muscle in situ. Am J Physiol 211, 177-183.
38. Zhang S, Bruton J, Katz A, et al. (2006) Limited oxygen diffusion accelerates fatigue development in mouse skeletal muscle. J Physiol 572, 551-559.
39. Harris W, Sands S, Windsor S, et al. (2004) Omega-3 fatty acids in cardiac biopsies from heart transplantation patients - correlation with erythrocytes and response to supplementation. Circulation 110, 1645-1649.
40. Ferreira L & Reid M (2008) Muscle-derived ROS and thiol regulation in muscle fatigue. J Appl Physiol 104, 853-860.
41. al Makdessi S, Brandle M, Ehrt M, et al. (1995) Myocardial protection by ischemic preconditioning: the influence of the composition of myocardial phospholipids. Mol Cell Biochem 145, 69-73.
42. Pansarasa O, D'Antona G, Gualea M, et al. (2002) "Oxidative stress": effects of mild endurance training and testosterone treatment on rat gastrocnemius muscle. Eur J Appl Physiol 87, 550-555.
43. Westerblab H, Bruton J & Katz A (2010) Skeletal muscle: energy metabolism, fibre types, fatigue and adaptability. Exp Cell Res 316, 3093-3099.
44. Abbatecola A, Cherubini A, Guralnik J, et al. (2009) Plasma polyunsaturated fatty acids and age-related physical performance decline. Rejuvenation Res 12, 25-32.
45. Slee E, McLennan P, Owen A, et al. (2010) Low dietary fish-oil threshold for myocardial membrane n-3 PUFA enrichment independent of n-6 PUFA intake in rats. J Lipid Res 51, 1841-1848.