메뉴 건너뛰기




Volumn 33, Issue 17, 2014, Pages 2191-2203

Dysregulation of BMI1 and microRNA-16 collaborate to enhance an anti-apoptotic potential in the side population of refractory mantle cell lymphoma

Author keywords

apoptosis; BMI1; mantle cell lymphoma; miR 16; Noxa; side population

Indexed keywords

BMI1 PROTEIN; BORTEZOMIB; DEXAMETHASONE; ETOPOSIDE; MICRORNA 16; PUROMYCIN; TETRACYCLINE;

EID: 84899656046     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.177     Document Type: Article
Times cited : (51)

References (58)
  • 1
    • 47349126802 scopus 로고    scopus 로고
    • Advances in the understanding of mantle cell lymphoma
    • Jares P, Campo E. Advances in the understanding of mantle cell lymphoma. Br J Haematol 2008; 142: 149-165.
    • (2008) Br J Haematol , vol.142 , pp. 149-165
    • Jares, P.1    Campo, E.2
  • 3
    • 0035866814 scopus 로고    scopus 로고
    • BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas
    • Beà S, Tort F, Pinyol M, Puig X, Hernández L, Hernández S et al. BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas. Cancer Res 2001; 61: 2409-2412.
    • (2001) Cancer Res , vol.61 , pp. 2409-2412
    • Beà, S.1    Tort, F.2    Pinyol, M.3    Puig, X.4    Hernández, L.5    Hernández, S.6
  • 4
    • 14844285335 scopus 로고    scopus 로고
    • Genome-wide arraybased CGH for mantle cell lymphoma: Identification of homozygous deletions of the proapoptotic gene BIM
    • Tagawa H, Karnan S, Suzuki R, Matsuo K, Zhang X, Ota A et al. Genome-wide arraybased CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM. Oncogene 2005; 24: 1348-1358.
    • (2005) Oncogene , vol.24 , pp. 1348-1358
    • Tagawa, H.1    Karnan, S.2    Suzuki, R.3    Matsuo, K.4    Zhang, X.5    Ota, A.6
  • 6
    • 64249136718 scopus 로고    scopus 로고
    • Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling
    • Beà S, Salaverria I, Armengol L, Pinyol M, Fernández V, Hartmann EM et al. Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling. Blood 2009; 113: 3059-3069.
    • (2009) Blood , vol.113 , pp. 3059-3069
    • Beà, S.1    Salaverria, I.2    Armengol, L.3    Pinyol, M.4    Fernández, V.5    Hartmann, E.M.6
  • 7
    • 0025773264 scopus 로고
    • Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2
    • van Lohuizen M, Frasch M, Wientjens E, Berns A. Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2. Nature 1991; 353: 353-355.
    • (1991) Nature , vol.353 , pp. 353-355
    • Van Lohuizen, M.1    Frasch, M.2    Wientjens, E.3    Berns, A.4
  • 8
    • 1642633053 scopus 로고    scopus 로고
    • Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
    • Leung C, Lingbeek M, Shakhova O, Liu J, Tanger E, Saremaslani P et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 2004; 428: 337-341.
    • (2004) Nature , vol.428 , pp. 337-341
    • Leung, C.1    Lingbeek, M.2    Shakhova, O.3    Liu, J.4    Tanger, E.5    Saremaslani, P.6
  • 9
    • 69449096782 scopus 로고    scopus 로고
    • BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases
    • Hoenerhoff MJ, Chu I, Barkan D, Liu ZY, Datta S, Dimri GP et al. BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases. Oncogene 2009; 28: 3022-3032.
    • (2009) Oncogene , vol.28 , pp. 3022-3032
    • Hoenerhoff, M.J.1    Chu, I.2    Barkan, D.3    Liu, Z.Y.4    Datta, S.5    Dimri, G.P.6
  • 10
    • 79551641545 scopus 로고    scopus 로고
    • Overexpression of BMI-1 promotes cell growth and resistance to cisplatin treatment in osteosarcoma
    • Wu Z, Min L, Chen D, Hao D, Duan Y, Qiu G et al. Overexpression of BMI-1 promotes cell growth and resistance to cisplatin treatment in osteosarcoma. PLoS One 2011; 6: e14648.
    • (2011) PLoS One , vol.6
    • Wu, Z.1    Min, L.2    Chen, D.3    Hao, D.4    Duan, Y.5    Qiu, G.6
  • 11
    • 81255138201 scopus 로고    scopus 로고
    • Reduced miR-128 in breast tumorinitiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5
    • Zhu Y, Yu F, Jiao Y, Feng J, Tang W, Yao H et al. Reduced miR-128 in breast tumorinitiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin Cancer Res 2011; 17: 7105-7015.
    • (2011) Clin Cancer Res , vol.17 , pp. 7105-7015
    • Zhu, Y.1    Yu, F.2    Jiao, Y.3    Feng, J.4    Tang, W.5    Yao, H.6
  • 12
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 1999; 397: 164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    Depinho, R.A.4    Van Lohuizen, M.5
  • 13
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
    • Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev 1999; 13: 2678-2690.
    • (1999) Genes Dev , vol.13 , pp. 2678-2690
    • Jacobs, J.J.1    Scheijen, B.2    Voncken, J.W.3    Kieboom, K.4    Berns, A.5    Van Lohuizen, M.6
  • 14
    • 72849130207 scopus 로고    scopus 로고
    • The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelialmesenchymal transition in human nasopharyngeal epithelial cells
    • Song LB, Li J, Liao WT, Feng Y, Yu CP, Hu LJ et al. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelialmesenchymal transition in human nasopharyngeal epithelial cells. J Clin Invest 2009; 119: 3626-3636.
    • (2009) J Clin Invest , vol.119 , pp. 3626-3636
    • Song, L.B.1    Li, J.2    Liao, W.T.3    Feng, Y.4    Yu, C.P.5    Hu, L.J.6
  • 15
    • 77954376911 scopus 로고    scopus 로고
    • The polycomb group protein Bmi-1 is essential for the growth of multiple myeloma cells
    • Jagani Z, Wiederschain D, Loo A, He D, Mosher R, Fordjour P et al. The polycomb group protein Bmi-1 is essential for the growth of multiple myeloma cells. Cancer Res 2010; 70: 5528-5538.
    • (2010) Cancer Res , vol.70 , pp. 5528-5538
    • Jagani, Z.1    Wiederschain, D.2    Loo, A.3    He, D.4    Mosher, R.5    Fordjour, P.6
  • 16
    • 79954745805 scopus 로고    scopus 로고
    • Bmi1 regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells
    • Kimura M, Takenobu H, Akita N, Nakazawa A, Ochiai H, Shimozato O et al. Bmi1 regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells. Cancer Sci 2011; 102: 983-990.
    • (2011) Cancer Sci , vol.102 , pp. 983-990
    • Kimura, M.1    Takenobu, H.2    Akita, N.3    Nakazawa, A.4    Ochiai, H.5    Shimozato, O.6
  • 17
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423: 255-260.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 18
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003; 425: 962-967.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 19
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006; 66: 6063-6071.
    • (2006) Cancer Res , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5    Jackson, K.W.6
  • 20
    • 50149092414 scopus 로고    scopus 로고
    • Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion
    • Dovey JS, Zacharek SJ, Kim CF, Lees JA. Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proc Natl Acad Sci USA 2008; 105: 11857-11862.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11857-11862
    • Dovey, J.S.1    Zacharek, S.J.2    Kim, C.F.3    Lees, J.A.4
  • 21
    • 54249132606 scopus 로고    scopus 로고
    • The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma
    • Chiba T, Miyagi S, Saraya A, Aoki R, Seki A, Morita Y et al. The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. Cancer Res 2008; 68: 7742-7749.
    • (2008) Cancer Res , vol.68 , pp. 7742-7749
    • Chiba, T.1    Miyagi, S.2    Saraya, A.3    Aoki, R.4    Seki, A.5    Morita, Y.6
  • 22
    • 0035877989 scopus 로고    scopus 로고
    • Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34CD38- progenitor cells from patients with acute myeloid leukemia
    • Feuring-Buske M, Hogge DE. Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34CD38- progenitor cells from patients with acute myeloid leukemia. Blood 2001; 97: 3882-3889.
    • (2001) Blood , vol.97 , pp. 3882-3889
    • Feuring-Buske, M.1    Hogge, D.E.2
  • 23
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001; 7: 1028-1034.
    • (2001) Nat Med , vol.7 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3    Colapietro, A.M.4    Sampath, J.5    Morris, J.J.6
  • 25
    • 22244433866 scopus 로고    scopus 로고
    • Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2 and ABCG2 cancer cells are similarly tumorigenic
    • Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2 and ABCG2 cancer cells are similarly tumorigenic. Cancer Res 2005; 65: 6207-6219.
    • (2005) Cancer Res , vol.65 , pp. 6207-6219
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Zhou, J.4    Claypool, K.5    Tang, D.G.6
  • 26
    • 33744985294 scopus 로고    scopus 로고
    • Characterization of a side population of cancer cells from human gastrointestinal system
    • Haraguchi N, Utsunomiya T, Inoue H, Tanaka F, Mimori K, Barnard GF et al. Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells 2006; 24: 506-513.
    • (2006) Stem Cells , vol.24 , pp. 506-513
    • Haraguchi, N.1    Utsunomiya, T.2    Inoue, H.3    Tanaka, F.4    Mimori, K.5    Barnard, G.F.6
  • 27
    • 33746625091 scopus 로고    scopus 로고
    • Ovarian cancer side population defines cells with stem cell-like characteristics and mullerian inhibiting substance responsiveness
    • Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, Dinulescu DM, Connolly D, Foster R et al. Ovarian cancer side population defines cells with stem cell-like characteristics and mullerian inhibiting substance responsiveness. Proc Natl Acad Sci USA 2006; 103: 11154-11159.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11154-11159
    • Szotek, P.P.1    Pieretti-Vanmarcke, R.2    Masiakos, P.T.3    Dinulescu, D.M.4    Connolly, D.5    Foster, R.6
  • 28
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • Ho MM, Ng AV, Lam S, Hung JY. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res 2007; 67: 4827-4833.
    • (2007) Cancer Res , vol.67 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 29
    • 33947427509 scopus 로고    scopus 로고
    • Characterization of side population in thyroid cancer cell lines: Cancer stem-like cells are enriched partly but not exclusively
    • Mitsutake N, Iwao A, Nagai K, Namba H, Ohtsuru A, Saenko V et al. Characterization of side population in thyroid cancer cell lines: cancer stem-like cells are enriched partly but not exclusively. Endocrinology 2007; 148: 1797-1803.
    • (2007) Endocrinology , vol.148 , pp. 1797-1803
    • Mitsutake, N.1    Iwao, A.2    Nagai, K.3    Namba, H.4    Ohtsuru, A.5    Saenko, V.6
  • 30
    • 34248529666 scopus 로고    scopus 로고
    • Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
    • Wang J, Guo LP, Chen LZ, Zeng YX, Lu SH. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 2007; 67: 3716-3724.
    • (2007) Cancer Res , vol.67 , pp. 3716-3724
    • Wang, J.1    Guo, L.P.2    Chen, L.Z.3    Zeng, Y.X.4    Lu, S.H.5
  • 31
    • 34548596706 scopus 로고    scopus 로고
    • Side population cells isolated from mesenchymal neoplasms have tumor initiating potential
    • Wu C, Wei Q, Utomo V, Nadesan P, Whetstone H, Kandel R et al. Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. Cancer Res 2007; 67: 8216-8222.
    • (2007) Cancer Res , vol.67 , pp. 8216-8222
    • Wu, C.1    Wei, Q.2    Utomo, V.3    Nadesan, P.4    Whetstone, H.5    Kandel, R.6
  • 34
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 2008; 68: 9125-9130.
    • (2008) Cancer Res , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3    Williams, S.4    Otsuki, A.5    Nuovo, G.6
  • 36
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138: 592-603.
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3    Lobo, N.4    Dalerba, P.5    Qian, D.6
  • 37
    • 80051793013 scopus 로고    scopus 로고
    • MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1
    • Dong P, Kaneuchi M, Watari H, Hamada J, Sudo S, Ju J et al. MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. Mol Cancer 2011; 10: 99.
    • (2011) Mol Cancer , vol.10 , pp. 99
    • Dong, P.1    Kaneuchi, M.2    Watari, H.3    Hamada, J.4    Sudo, S.5    Ju, J.6
  • 38
    • 84856222156 scopus 로고    scopus 로고
    • MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1
    • Sun L, Yao Y, Liu B, Lin Z, Lin L, Yang M et al. MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. Oncogene 2012; 31: 432-445.
    • (2012) Oncogene , vol.31 , pp. 432-445
    • Sun, L.1    Yao, Y.2    Liu, B.3    Lin, Z.4    Lin, L.5    Yang, M.6
  • 40
    • 20044376092 scopus 로고    scopus 로고
    • Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
    • O'Connor OA, Wright J, Moskowitz C, Muzzy J, MacGregor-Cortelli B, Stubblefield M et al. Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 2005; 23: 676-684.
    • (2005) J Clin Oncol , vol.23 , pp. 676-684
    • O'connor, O.A.1    Wright, J.2    Moskowitz, C.3    Muzzy, J.4    Macgregor-Cortelli, B.5    Stubblefield, M.6
  • 41
    • 33750625445 scopus 로고    scopus 로고
    • Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma
    • Fisher RI, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 2006; 24: 4867-4874.
    • (2006) J Clin Oncol , vol.24 , pp. 4867-4874
    • Fisher, R.I.1    Bernstein, S.H.2    Kahl, B.S.3    Djulbegovic, B.4    Robertson, M.J.5    De Vos, S.6
  • 42
    • 33947134834 scopus 로고    scopus 로고
    • The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
    • Bracken AP, Kleine-Kohlbrecher D, Dietrich N, Pasini D, Gargiulo G, Beekman C et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev 2007; 21: 525-530.
    • (2007) Genes Dev , vol.21 , pp. 525-530
    • Bracken, A.P.1    Kleine-Kohlbrecher, D.2    Dietrich, N.3    Pasini, D.4    Gargiulo, G.5    Beekman, C.6
  • 43
    • 35148840173 scopus 로고    scopus 로고
    • Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
    • Bruggeman SW, Hulsman D, Tanger E, Buckle T, Biom M, Zevenhoven J et al. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 2007; 12: 328-341.
    • (2007) Cancer Cell , vol.12 , pp. 328-341
    • Bruggeman, S.W.1    Hulsman, D.2    Tanger, E.3    Buckle, T.4    Biom, M.5    Zevenhoven, J.6
  • 44
    • 53049085085 scopus 로고    scopus 로고
    • BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression
    • Douglas D, Hsu JH, Hung L, Cooper A, Abdueva D, van Doorninck J et al. BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression. Cancer Res 2008; 68: 6507-6515.
    • (2008) Cancer Res , vol.68 , pp. 6507-6515
    • Douglas, D.1    Hsu, J.H.2    Hung, L.3    Cooper, A.4    Abdueva, D.5    Van Doorninck, J.6
  • 45
    • 27644570319 scopus 로고    scopus 로고
    • A microRNA cluster as a target of genomic amplification in malignant lymphoma
    • Tagawa H, Seto M. A microRNA cluster as a target of genomic amplification in malignant lymphoma. Leukemia 2005; 19: 2013-2016.
    • (2005) Leukemia , vol.19 , pp. 2013-2016
    • Tagawa, H.1    Seto, M.2
  • 46
    • 50949125416 scopus 로고    scopus 로고
    • Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma
    • Chen RW, Bemis LT, Amato CM, Myint H, Tran H, Birks DK et al. Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. Blood 2008; 112: 822-829.
    • (2008) Blood , vol.112 , pp. 822-829
    • Chen, R.W.1    Bemis, L.T.2    Amato, C.M.3    Myint, H.4    Tran, H.5    Birks, D.K.6
  • 47
    • 77951003346 scopus 로고    scopus 로고
    • MicroRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
    • Zhao JJ, Lin J, Lwin T, Yang H, Guo J, Kong W et al. microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma. Blood 2010; 115: 2630-2639.
    • (2010) Blood , vol.115 , pp. 2630-2639
    • Zhao, J.J.1    Lin, J.2    Lwin, T.3    Yang, H.4    Guo, J.5    Kong, W.6
  • 48
    • 58849148000 scopus 로고    scopus 로고
    • MicroRNA-17- 92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes
    • Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N, Sawada K. MicroRNA-17- 92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 2009; 113: 396-402.
    • (2009) Blood , vol.113 , pp. 396-402
    • Inomata, M.1    Tagawa, H.2    Guo, Y.M.3    Kameoka, Y.4    Takahashi, N.5    Sawada, K.6
  • 50
    • 79954459249 scopus 로고    scopus 로고
    • MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin e
    • Ofir M, Hacohen D, Ginsberg D. miR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin E. Mol Cancer Res 2011; 9: 440-447.
    • (2011) Mol Cancer Res , vol.9 , pp. 440-447
    • Ofir, M.1    Hacohen, D.2    Ginsberg, D.3
  • 51
    • 84860788476 scopus 로고    scopus 로고
    • Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
    • Rivas MA, Venturutti L, Huang YW, Schillaci R, Huang THM, Elizalde PV. Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. Breast Cancer Res 2012; 14: R77.
    • (2012) Breast Cancer Res , vol.14
    • Rivas, M.A.1    Venturutti, L.2    Huang, Y.W.3    Schillaci, R.4    Huang, T.H.M.5    Elizalde, P.V.6
  • 52
    • 84869216065 scopus 로고    scopus 로고
    • Cisplatin sensitivity mediated by WEE1 and CHK1 is mediated by miR-155 and the miR-15 family
    • Pouliot LM, Chen YC, Bai J, Guha R, Martin SE, Gottesman MM et al. Cisplatin sensitivity mediated by WEE1 and CHK1 is mediated by miR-155 and the miR-15 family. Cancer Res 2012; 72: 5945-5955.
    • (2012) Cancer Res , vol.72 , pp. 5945-5955
    • Pouliot, L.M.1    Chen, Y.C.2    Bai, J.3    Guha, R.4    Martin, S.E.5    Gottesman, M.M.6
  • 53
    • 84866125820 scopus 로고    scopus 로고
    • MicroRNA-16 is downregulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and Interacts with Pim-1
    • Kim KT, Carroll AP, Mashkani B, Cairns MJ, Small D, Scott RJ. MicroRNA-16 is downregulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and Interacts with Pim-1. PLoS One 2012; 7: e44546.
    • (2012) PLoS One , vol.7
    • Kim, K.T.1    Carroll, A.P.2    Mashkani, B.3    Cairns, M.J.4    Small, D.5    Scott, R.J.6
  • 54
    • 84856195948 scopus 로고    scopus 로고
    • MiR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene
    • Zhou R, Li X, Hu G, Gong AY, Drescher KM, Chen XM. MiR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene. PLoS One 2012; 7: e30772.
    • (2012) PLoS One , vol.7
    • Zhou, R.1    Li, X.2    Hu, G.3    Gong, A.Y.4    Drescher, K.M.5    Chen, X.M.6
  • 57
    • 77956896318 scopus 로고    scopus 로고
    • Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway
    • Zhang X, Wan G, Mlotshwa S, Vance V, Berger FG, Chen H et al. Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway. Cancer Res 2010; 70: 7176-7186.
    • (2010) Cancer Res , vol.70 , pp. 7176-7186
    • Zhang, X.1    Wan, G.2    Mlotshwa, S.3    Vance, V.4    Berger, F.G.5    Chen, H.6
  • 58
    • 18344410760 scopus 로고    scopus 로고
    • NOD/SCID/ gamma(c)(null)mouse: An excellent recipient mouse model for engraftment of human cells
    • Ito M, Hiramatsu H, Kobayashi K, Suzue K, Kawahata M, Hioki K et al. NOD/SCID/ gamma(c)(null)mouse: an excellent recipient mouse model for engraftment of human cells. Blood 2002; 100: 3175-3182.
    • (2002) Blood , vol.100 , pp. 3175-3182
    • Ito, M.1    Hiramatsu, H.2    Kobayashi, K.3    Suzue, K.4    Kawahata, M.5    Hioki, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.