-
1
-
-
50249084003
-
Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering
-
10.1016/j.ymben.2008.07.001, 18674632
-
Olano C, Lombo F, Mendez C, Salas JA. Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering. Metab Eng 2008, 10(5):281-292. 10.1016/j.ymben.2008.07.001, 18674632.
-
(2008)
Metab Eng
, vol.10
, Issue.5
, pp. 281-292
-
-
Olano, C.1
Lombo, F.2
Mendez, C.3
Salas, J.A.4
-
2
-
-
43049136820
-
Combinatorial engineering of microbes for optimizing cellular phenotype
-
10.1016/j.cbpa.2008.01.017, 18275860
-
Santos CN, Stephanopoulos G. Combinatorial engineering of microbes for optimizing cellular phenotype. Curr Opin Chem Biol 2008, 12(2):168-176. 10.1016/j.cbpa.2008.01.017, 18275860.
-
(2008)
Curr Opin Chem Biol
, vol.12
, Issue.2
, pp. 168-176
-
-
Santos, C.N.1
Stephanopoulos, G.2
-
3
-
-
0028998750
-
The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences
-
10.1073/pnas.92.13.6200, 41670, 7597101
-
Fierro F, Barredo JL, Diez B, Gutierrez S, Fernandez FJ, Martin JF. The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences. Proc Natl Acad Sci USA 1995, 92(13):6200-6204. 10.1073/pnas.92.13.6200, 41670, 7597101.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.13
, pp. 6200-6204
-
-
Fierro, F.1
Barredo, J.L.2
Diez, B.3
Gutierrez, S.4
Fernandez, F.J.5
Martin, J.F.6
-
4
-
-
0029084746
-
Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11
-
10.1111/j.1365-2958.1995.tb02338.x, 8577249
-
Peschke U, Schmidt H, Zhang HZ, Piepersberg W. Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11. Mol Microbiol 1995, 16(6):1137-1156. 10.1111/j.1365-2958.1995.tb02338.x, 8577249.
-
(1995)
Mol Microbiol
, vol.16
, Issue.6
, pp. 1137-1156
-
-
Peschke, U.1
Schmidt, H.2
Zhang, H.Z.3
Piepersberg, W.4
-
5
-
-
33745438016
-
Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus
-
10.1073/pnas.0603251103, 1475798,1475798, 16766657
-
Yanai K, Murakami T, Bibb M. Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus. Proc Natl Acad Sci USA 2006, 103(25):9661-9666. 10.1073/pnas.0603251103, 1475798,1475798, 16766657.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.25
, pp. 9661-9666
-
-
Yanai, K.1
Murakami, T.2
Bibb, M.3
-
6
-
-
0031664853
-
A new logic for DNA engineering using recombination in Escherichia coli
-
10.1038/2417, 9771703
-
Zhang Y, Buchholz F, Muyrers JP, Stewart AF. A new logic for DNA engineering using recombination in Escherichia coli. Nat Genet 1998, 20(2):123-128. 10.1038/2417, 9771703.
-
(1998)
Nat Genet
, vol.20
, Issue.2
, pp. 123-128
-
-
Zhang, Y.1
Buchholz, F.2
Muyrers, J.P.3
Stewart, A.F.4
-
7
-
-
0033668496
-
DNA cloning by homologous recombination in Escherichia coli
-
10.1038/82449, 11101815
-
Zhang Y, Muyrers JP, Testa G, Stewart AF. DNA cloning by homologous recombination in Escherichia coli. Nat Biotechnol 2000, 18(12):1314-1317. 10.1038/82449, 11101815.
-
(2000)
Nat Biotechnol
, vol.18
, Issue.12
, pp. 1314-1317
-
-
Zhang, Y.1
Muyrers, J.P.2
Testa, G.3
Stewart, A.F.4
-
8
-
-
15744370033
-
Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering
-
10.1016/j.chembiol.2004.12.012, 15797219
-
Wenzel SC, Gross F, Zhang Y, Fu J, Stewart AF, Muller R. Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering. Chem Biol 2005, 12(3):349-356. 10.1016/j.chembiol.2004.12.012, 15797219.
-
(2005)
Chem Biol
, vol.12
, Issue.3
, pp. 349-356
-
-
Wenzel, S.C.1
Gross, F.2
Zhang, Y.3
Fu, J.4
Stewart, A.F.5
Muller, R.6
-
9
-
-
33845511743
-
Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus
-
10.1128/AEM.01503-06, 1694261, 16997979
-
Perlova O, Fu J, Kuhlmann S, Krug D, Stewart AF, Zhang Y, Muller R. Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus. Appl Environ Microbiol 2006, 72(12):7485-7494. 10.1128/AEM.01503-06, 1694261, 16997979.
-
(2006)
Appl Environ Microbiol
, vol.72
, Issue.12
, pp. 7485-7494
-
-
Perlova, O.1
Fu, J.2
Kuhlmann, S.3
Krug, D.4
Stewart, A.F.5
Zhang, Y.6
Muller, R.7
-
10
-
-
40949149509
-
Assembly and heterologous expression of the coumermycin A1 gene cluster and production of new derivatives by genetic engineering
-
10.1002/cbic.200700483, 18288655
-
Wolpert M, Heide L, Kammerer B, Gust B. Assembly and heterologous expression of the coumermycin A1 gene cluster and production of new derivatives by genetic engineering. Chembiochem 2008, 9(4):603-612. 10.1002/cbic.200700483, 18288655.
-
(2008)
Chembiochem
, vol.9
, Issue.4
, pp. 603-612
-
-
Wolpert, M.1
Heide, L.2
Kammerer, B.3
Gust, B.4
-
11
-
-
48849100401
-
Heterologous expression and genetic engineering of the phenalinolactone biosynthetic gene cluster by using red/ET recombineering
-
10.1002/cbic.200700549, 18157854
-
Binz TM, Wenzel SC, Schnell HJ, Bechthold A, Muller R. Heterologous expression and genetic engineering of the phenalinolactone biosynthetic gene cluster by using red/ET recombineering. Chembiochem 2008, 9(3):447-454. 10.1002/cbic.200700549, 18157854.
-
(2008)
Chembiochem
, vol.9
, Issue.3
, pp. 447-454
-
-
Binz, T.M.1
Wenzel, S.C.2
Schnell, H.J.3
Bechthold, A.4
Muller, R.5
-
12
-
-
48649111173
-
Reassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes
-
10.1002/cbic.200800029, 18512205
-
Hu Y, Phelan VV, Farnet CM, Zazopoulos E, Bachmann BO. Reassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes. Chembiochem 2008, 9(10):1603-1608. 10.1002/cbic.200800029, 18512205.
-
(2008)
Chembiochem
, vol.9
, Issue.10
, pp. 1603-1608
-
-
Hu, Y.1
Phelan, V.V.2
Farnet, C.M.3
Zazopoulos, E.4
Bachmann, B.O.5
-
13
-
-
55249090459
-
Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition
-
10.1093/nar/gkn499, 2553598, 18701643
-
Fu J, Wenzel SC, Perlova O, Wang J, Gross F, Tang Z, Yin Y, Stewart AF, Muller R, Zhang Y. Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition. Nucleic Acids Res 2008, 36(17):e113. 10.1093/nar/gkn499, 2553598, 18701643.
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.17
-
-
Fu, J.1
Wenzel, S.C.2
Perlova, O.3
Wang, J.4
Gross, F.5
Tang, Z.6
Yin, Y.7
Stewart, A.F.8
Muller, R.9
Zhang, Y.10
-
14
-
-
0027439619
-
Compounds active against cell walls of medically important fungi
-
358263, 8457977
-
Hector RF. Compounds active against cell walls of medically important fungi. Clin Microbiol Rev 1993, 6(1):1-21. 358263, 8457977.
-
(1993)
Clin Microbiol Rev
, vol.6
, Issue.1
, pp. 1-21
-
-
Hector, R.F.1
-
15
-
-
0035145615
-
Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin
-
10.1007/s004380000352, 11212921
-
Lauer B, Russwurm R, Schwarz W, Kalmanczhelyi A, Bruntner C, Rosemeier A, Bormann C. Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin. Mol Gen Genet 2001, 264(5):662-673. 10.1007/s004380000352, 11212921.
-
(2001)
Mol Gen Genet
, vol.264
, Issue.5
, pp. 662-673
-
-
Lauer, B.1
Russwurm, R.2
Schwarz, W.3
Kalmanczhelyi, A.4
Bruntner, C.5
Rosemeier, A.6
Bormann, C.7
-
16
-
-
0032850662
-
Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin
-
Bruntner C, Lauer B, Schwarz W, Mohrle V, Bormann C. Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin. Mol Gen Genet 1999, 262(1):102-114.
-
(1999)
Mol Gen Genet
, vol.262
, Issue.1
, pp. 102-114
-
-
Bruntner, C.1
Lauer, B.2
Schwarz, W.3
Mohrle, V.4
Bormann, C.5
-
17
-
-
15944401749
-
A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces ansochromogenes that also influences colony development
-
10.1111/j.1365-2958.2005.04512.x, 15752205
-
Liu G, Tian Y, Yang H, Tan H. A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces ansochromogenes that also influences colony development. Mol Microbiol 2005, 55(6):1855-1866. 10.1111/j.1365-2958.2005.04512.x, 15752205.
-
(2005)
Mol Microbiol
, vol.55
, Issue.6
, pp. 1855-1866
-
-
Liu, G.1
Tian, Y.2
Yang, H.3
Tan, H.4
-
18
-
-
71549152006
-
Structure and Function of Gene Involved in Nikkomycin Biosynthesis and Differentiation in Streptomyces ansochromogenes. PhD Dissertation
-
Beijing: Institute of microbiology, CAS
-
Li W. Structure and Function of Gene Involved in Nikkomycin Biosynthesis and Differentiation in Streptomyces ansochromogenes. PhD Dissertation. 2003, Beijing: Institute of microbiology, CAS.
-
(2003)
-
-
Li, W.1
-
19
-
-
0035916383
-
Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes
-
10.1002/1097-0290(20000220)72:4<379::AID-BIT1000>3.0.CO;2-5, 11180058
-
Theilgaard H, Berg M, Mulder C, Bovenberg R, Nielsen J. Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes. Biotechnol Bioeng 2001, 72(4):379-388. 10.1002/1097-0290(20000220)72:4<379::AID-BIT1000>3.0.CO;2-5, 11180058.
-
(2001)
Biotechnol Bioeng
, vol.72
, Issue.4
, pp. 379-388
-
-
Theilgaard, H.1
Berg, M.2
Mulder, C.3
Bovenberg, R.4
Nielsen, J.5
-
20
-
-
67349212638
-
Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum
-
10.1007/s00253-009-1933-8, 19277641
-
Baba S, Abe Y, Suzuki T, Ono C, Iwamoto K, Nihira T, Hosobuchi M. Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum. Appl Microbiol Biotechnol 2009, 83(4):697-704. 10.1007/s00253-009-1933-8, 19277641.
-
(2009)
Appl Microbiol Biotechnol
, vol.83
, Issue.4
, pp. 697-704
-
-
Baba, S.1
Abe, Y.2
Suzuki, T.3
Ono, C.4
Iwamoto, K.5
Nihira, T.6
Hosobuchi, M.7
-
21
-
-
0023720742
-
Cloning and Expression of a DNA Sequence Conferring Cephamycin C Production
-
Chen CW, Lin H-F, Kuo CL, Tsai H-L, Tsai JF-Y. Cloning and Expression of a DNA Sequence Conferring Cephamycin C Production. Bio/Technology 1988, 6:1222-1224.
-
(1988)
Bio/Technology
, vol.6
, pp. 1222-1224
-
-
Chen, C.W.1
Lin, H.-.F.2
Kuo, C.L.3
Tsai, H.-.L.4
Tsai, J.F.-.Y.5
-
22
-
-
0026645203
-
Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp
-
10.1016/0378-1119(92)90627-2, 1628843
-
Bierman M, Logan R, O'Brien K, Seno ET, Rao RN, Schoner BE. Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene 1992, 116(1):43-49. 10.1016/0378-1119(92)90627-2, 1628843.
-
(1992)
Gene
, vol.116
, Issue.1
, pp. 43-49
-
-
Bierman, M.1
Logan, R.2
O'Brien, K.3
Seno, E.T.4
Rao, R.N.5
Schoner, B.E.6
-
23
-
-
64549084934
-
Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids
-
10.1016/j.plasmid.2008.12.002, 19167423
-
Ostash B, Makitrinskyy R, Walker S, Fedorenko V. Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids. Plasmid 2009, 61(3):171-175. 10.1016/j.plasmid.2008.12.002, 19167423.
-
(2009)
Plasmid
, vol.61
, Issue.3
, pp. 171-175
-
-
Ostash, B.1
Makitrinskyy, R.2
Walker, S.3
Fedorenko, V.4
-
24
-
-
68449103617
-
Stabilized gene duplication enables long-term selection-free heterologous pathway expression
-
10.1038/nbt.1555, 19633654
-
Tyo KE, Ajikumar PK, Stephanopoulos G. Stabilized gene duplication enables long-term selection-free heterologous pathway expression. Nat Biotechnol 2009, 27(8):760-765. 10.1038/nbt.1555, 19633654.
-
(2009)
Nat Biotechnol
, vol.27
, Issue.8
, pp. 760-765
-
-
Tyo, K.E.1
Ajikumar, P.K.2
Stephanopoulos, G.3
-
25
-
-
0002200089
-
An overview of nikkomycins: history, biochemistry and applications
-
New York: Marcel Dekker, Inc, Rippon JW, Fromtling RA
-
Fiedler H-P, Schuz T, Decker H. An overview of nikkomycins: history, biochemistry and applications. Cutaneous antifungal agents:selected compounds in clinical practice and development 1993, 325-352. New York: Marcel Dekker, Inc, Rippon JW, Fromtling RA.
-
(1993)
Cutaneous antifungal agents:selected compounds in clinical practice and development
, pp. 325-352
-
-
Fiedler, H.-.P.1
Schuz, T.2
Decker, H.3
-
26
-
-
0036008124
-
Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics
-
10.1016/S1074-5521(02)00090-X, 11841943
-
Chen H, Hubbard BK, O'Connor SE, Walsh CT. Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics. Chem Biol 2002, 9(1):103-112. 10.1016/S1074-5521(02)00090-X, 11841943.
-
(2002)
Chem Biol
, vol.9
, Issue.1
, pp. 103-112
-
-
Chen, H.1
Hubbard, B.K.2
O'Connor, S.E.3
Walsh, C.T.4
-
27
-
-
1342288690
-
Enhanced production of nikkomycin X by over-expression of SanO, a non-ribosomal peptide synthetase in Streptomyces ansochromogenes
-
10.1023/B:BILE.0000013720.14278.07, 15049368
-
Wang G, Tan H. Enhanced production of nikkomycin X by over-expression of SanO, a non-ribosomal peptide synthetase in Streptomyces ansochromogenes. Biotechnol Lett 2004, 26(3):229-233. 10.1023/B:BILE.0000013720.14278.07, 15049368.
-
(2004)
Biotechnol Lett
, vol.26
, Issue.3
, pp. 229-233
-
-
Wang, G.1
Tan, H.2
-
28
-
-
0003869903
-
Practical Streptomyces Genetics
-
the John Innes Foundation, Norwich, England
-
Kieser T, Bibb MJ, Buttner MJ, Chater KF, Hopwood DA. Practical Streptomyces Genetics. 2000, the John Innes Foundation, Norwich, England.
-
(2000)
-
-
Kieser, T.1
Bibb, M.J.2
Buttner, M.J.3
Chater, K.F.4
Hopwood, D.A.5
-
29
-
-
0036785364
-
The streptomyces genome contains multiple pseudo-attB sites for the (phi)C31-encoded site-specific recombination system
-
10.1128/JB.184.20.5746-5752.2002, 139614, 12270833
-
Combes P, Till R, Bee S, Smith MC. The streptomyces genome contains multiple pseudo-attB sites for the (phi)C31-encoded site-specific recombination system. J Bacteriol 2002, 184(20):5746-5752. 10.1128/JB.184.20.5746-5752.2002, 139614, 12270833.
-
(2002)
J Bacteriol
, vol.184
, Issue.20
, pp. 5746-5752
-
-
Combes, P.1
Till, R.2
Bee, S.3
Smith, M.C.4
-
30
-
-
0021768599
-
Screening for new microbial products by high-performance liquid chromatography using a photodiode array detector
-
10.1016/S0021-9673(00)96176-4, 6530423
-
Fiedler HP. Screening for new microbial products by high-performance liquid chromatography using a photodiode array detector. J Chromatogr 1984, 316:487-494. 10.1016/S0021-9673(00)96176-4, 6530423.
-
(1984)
J Chromatogr
, vol.316
, pp. 487-494
-
-
Fiedler, H.P.1
-
31
-
-
0036716276
-
Cloning and function of sanQ: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes
-
10.1007/s00284-001-0115-4, 12177738
-
Zeng H, Tan H, Li J. Cloning and function of sanQ: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes. Curr Microbiol 2002, 45(3):175-179. 10.1007/s00284-001-0115-4, 12177738.
-
(2002)
Curr Microbiol
, vol.45
, Issue.3
, pp. 175-179
-
-
Zeng, H.1
Tan, H.2
Li, J.3
-
32
-
-
0033047685
-
A putative two-component signal transduction system regulates sigmaE, a sigma factor required for normal cell wall integrity in Streptomyces coelicolor A3(2)
-
10.1046/j.1365-2958.1999.01452.x, 10411727
-
Paget MS, Leibovitz E, Buttner MJ. A putative two-component signal transduction system regulates sigmaE, a sigma factor required for normal cell wall integrity in Streptomyces coelicolor A3(2). Mol Microbiol 1999, 33(1):97-107. 10.1046/j.1365-2958.1999.01452.x, 10411727.
-
(1999)
Mol Microbiol
, vol.33
, Issue.1
, pp. 97-107
-
-
Paget, M.S.1
Leibovitz, E.2
Buttner, M.J.3
-
33
-
-
0037452723
-
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
-
10.1073/pnas.0337542100, 149868, 12563033
-
Gust B, Challis GL, Fowler K, Kieser T, Chater KF. PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. Proc Natl Acad Sci USA 2003, 100(4):1541-1546. 10.1073/pnas.0337542100, 149868, 12563033.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.4
, pp. 1541-1546
-
-
Gust, B.1
Challis, G.L.2
Fowler, K.3
Kieser, T.4
Chater, K.F.5
|