Recombinant expression and functional characterization of martentoxin: A selective inhibitor for BK channel (α + β4)

Toxins

Volumn 6, Issue 4, 2014, Pages 1419-1433

  Tao, Jie ^a   Zhou, Zhi Lei ^a   Wu, Bin ^a   Shi, Jian ^a   Chen, Xiao Ming ^a   Ji, Yong Hua ^a  

^a SHANGHAI UNIVERSITY   (China)

Author keywords

BK channels; Expression and purification; Martentoxin; Short chain scorpion toxins

Indexed keywords

ENTEROPEPTIDASE; MARTENTOXIN; POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM; UNCLASSIFIED DRUG; KCNMA1 PROTEIN, HUMAN; KCNMB4 PROTEIN, HUMAN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL BETA SUBUNIT; MARTENTOXIN, BUTHUS MARTENSI; NERVE PROTEIN; RECOMBINANT PROTEIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE SEQUENCE; HUMAN; HUMAN CELL; IC 50; MOLECULAR DYNAMICS; NERVE CELL EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CONDUCTANCE; PROTEIN EXPRESSION; WHOLE CELL PATCH CLAMP; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; MEMBRANE POTENTIAL; METABOLISM; MOLECULAR GENETICS; MOLECULAR WEIGHT;

AMINO ACID SEQUENCE; HEK293 CELLS; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BETA SUBUNITS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NERVE TISSUE PROTEINS; POTASSIUM CHANNEL BLOCKERS; RECOMBINANT PROTEINS; SCORPION VENOMS; TRANSFECTION;

EID: 84899652142     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins6041419     Document Type: Article

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