메뉴 건너뛰기




Volumn 2, Issue 6, 2011, Pages 437-444

Exploring the obscure profiles of pharmacological binding sites on voltage-gated sodium channels by BmK neurotoxins

Author keywords

receptor sites; scorpion neurotoxins; voltage gated sodium channel

Indexed keywords

NEUROTOXIN; SCORPION VENOM; VOLTAGE GATED SODIUM CHANNEL;

EID: 80053082112     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-011-1064-8     Document Type: Review
Times cited : (17)

References (64)
  • 1
    • 0034022325 scopus 로고    scopus 로고
    • Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2
    • Amaya, F., Decosterd, I., Samad, T. A., Plumpton, C., Tate, S., Mannion, R. J., Costigan, M., and Woolf, C. J. (2000). Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2. Mol Cell Neurosci 15, 331-342.
    • (2000) Mol Cell Neurosci , vol.15 , pp. 331-342
    • Amaya, F.1    Decosterd, I.2    Samad, T.A.3    Plumpton, C.4    Tate, S.5    Mannion, R.J.6    Costigan, M.7    Woolf, C.J.8
  • 2
    • 0024810594 scopus 로고
    • Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development
    • Beckh, S., Noda, M., Lübbert, H., and Numa, S. (1989). Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development. EMBO J 8, 3611-3616.
    • (1989) EMBO J , vol.8 , pp. 3611-3616
    • Beckh, S.1    Noda, M.2    Lübbert, H.3    Numa, S.4
  • 3
    • 0031972937 scopus 로고    scopus 로고
    • A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B
    • Benzinger, G. R., Kyle, J. W., Blumenthal, K. M., and Hanck, D. A. (1998). A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B. J Biol Chem 273, 80-84.
    • (1998) J Biol Chem , vol.273 , pp. 80-84
    • Benzinger, G.R.1    Kyle, J.W.2    Blumenthal, K.M.3    Hanck, D.A.4
  • 5
    • 0029026638 scopus 로고
    • Structure and function of voltage-gated ion channels
    • Catterall, W. A. (1995). Structure and function of voltage-gated ion channels. Annu Rev Biochem 64, 493-531.
    • (1995) Annu Rev Biochem , vol.64 , pp. 493-531
    • Catterall, W.A.1
  • 6
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels
    • Catterall, W. A. (2000). From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 26, 13-25.
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 7
    • 0033731909 scopus 로고    scopus 로고
    • Molecular mechanisms of neurotoxin action on voltage-gated sodium channels
    • Cestèle, S., and Catterall, W. A. (2000). Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. Biochimie 82, 883-892.
    • (2000) Biochimie , vol.82 , pp. 883-892
    • Cestèle, S.1    Catterall, W.A.2
  • 8
    • 0031020104 scopus 로고    scopus 로고
    • Biochemical and pharmacological characterization of a depressant insect toxin from the venom of the scorpion Buthacus arenicola
    • Cestèle, S., Kopeyan, C., Oughideni, R., Mansuelle, P., Granier, C., and Rochat, H. (1997). Biochemical and pharmacological characterization of a depressant insect toxin from the venom of the scorpion Buthacus arenicola. Eur J Biochem 243, 93-99.
    • (1997) Eur J Biochem , vol.243 , pp. 93-99
    • Cestèle, S.1    Kopeyan, C.2    Oughideni, R.3    Mansuelle, P.4    Granier, C.5    Rochat, H.6
  • 9
    • 0032191111 scopus 로고    scopus 로고
    • Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II
    • Cestèle, S., Qu, Y., Rogers, J. C., Rochat, H., Scheuer, T., and Catterall, W. A. (1998). Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II. Neuron 21, 919-931.
    • (1998) Neuron , vol.21 , pp. 919-931
    • Cestèle, S.1    Qu, Y.2    Rogers, J.C.3    Rochat, H.4    Scheuer, T.5    Catterall, W.A.6
  • 10
    • 33746369777 scopus 로고    scopus 로고
    • Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin
    • Cestèle, S., Yarov-Yarovoy, V., Qu, Y., Sampieri, F., Scheuer, T., and Catterall, W. A. (2006). Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin. J Biol Chem 281, 21332-21344.
    • (2006) J Biol Chem , vol.281 , pp. 21332-21344
    • Cestèle, S.1    Yarov-Yarovoy, V.2    Qu, Y.3    Sampieri, F.4    Scheuer, T.5    Catterall, W.A.6
  • 11
    • 33745966848 scopus 로고    scopus 로고
    • The binding of BmK IT2 on mammal and insect sodium channels by surface plasmon resonance assay
    • Chai, Z. F., Bai, Z. T., Liu, T., Pang, X. Y., and Ji, Y. H. (2006a). The binding of BmK IT2 on mammal and insect sodium channels by surface plasmon resonance assay. Pharmacol Res 54, 85-90.
    • (2006) Pharmacol Res , vol.54 , pp. 85-90
    • Chai, Z.F.1    Bai, Z.T.2    Liu, T.3    Pang, X.Y.4    Ji, Y.H.5
  • 12
    • 33750535382 scopus 로고    scopus 로고
    • Chinese-scorpion (Buthus martensi Karsch) toxin BmK alphaIV, a novel modulator of sodium channels: from genomic organization to functional analysis
    • Chai, Z. F., Zhu, M. M., Bai, Z. T., Liu, T., Tan, M., Pang, X. Y., and Ji, Y. H. (2006b). Chinese-scorpion (Buthus martensi Karsch) toxin BmK alphaIV, a novel modulator of sodium channels: from genomic organization to functional analysis. Biochem J 399, 445-453.
    • (2006) Biochem J , vol.399 , pp. 445-453
    • Chai, Z.F.1    Zhu, M.M.2    Bai, Z.T.3    Liu, T.4    Tan, M.5    Pang, X.Y.6    Ji, Y.H.7
  • 13
    • 35548983328 scopus 로고    scopus 로고
    • Design of a specific activator for skeletal muscle sodium channels uncovers channel architecture
    • Cohen, L., Ilan, N., Gur, M., Stühmer, W., Gordon, D., and Gurevitz, M. (2007). Design of a specific activator for skeletal muscle sodium channels uncovers channel architecture. J Biol Chem 282, 29424-29430.
    • (2007) J Biol Chem , vol.282 , pp. 29424-29430
    • Cohen, L.1    Ilan, N.2    Gur, M.3    Stühmer, W.4    Gordon, D.5    Gurevitz, M.6
  • 14
    • 0020004059 scopus 로고
    • Two types of scorpion receptor sites, one related to the activation, the other to the inactivation of the action potential sodium channel
    • Couraud, F., Jover, E., Dubois, J. M., and Rochat, H. (1982). Two types of scorpion receptor sites, one related to the activation, the other to the inactivation of the action potential sodium channel. Toxicon 20, 9-16.
    • (1982) Toxicon , vol.20 , pp. 9-16
    • Couraud, F.1    Jover, E.2    Dubois, J.M.3    Rochat, H.4
  • 15
    • 0020616428 scopus 로고
    • Photoaffinity labeling of alpha- and beta- scorpion toxin receptors associated with rat brain sodium channel
    • Darbon, H., Jover, E., Couraud, F., and Rochat, H. (1983). Photoaffinity labeling of alpha- and beta- scorpion toxin receptors associated with rat brain sodium channel. Biochem Biophys Res Commun 115, 415-422.
    • (1983) Biochem Biophys Res Commun , vol.115 , pp. 415-422
    • Darbon, H.1    Jover, E.2    Couraud, F.3    Rochat, H.4
  • 17
    • 0031840375 scopus 로고    scopus 로고
    • Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo
    • Dib-Hajj, S. D., Black, J. A., Cummins, T. R., Kenney, A. M., Kocsis, J. D., and Waxman, S. G. (1998). Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. J Neurophysiol 79, 2668-2676.
    • (1998) J Neurophysiol , vol.79 , pp. 2668-2676
    • Dib-Hajj, S.D.1    Black, J.A.2    Cummins, T.R.3    Kenney, A.M.4    Kocsis, J.D.5    Waxman, S.G.6
  • 18
    • 0031081496 scopus 로고    scopus 로고
    • A single amino acid change in the para sodium channel protein is associated with knockdown-resistance (kdr) to pyrethroid insecticides in German cockroach
    • Dong, K. (1997). A single amino acid change in the para sodium channel protein is associated with knockdown-resistance (kdr) to pyrethroid insecticides in German cockroach. Insect Biochem Mol Biol 27, 93-100.
    • (1997) Insect Biochem Mol Biol , vol.27 , pp. 93-100
    • Dong, K.1
  • 19
    • 0029091192 scopus 로고
    • Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function
    • Feng, G., Deák, P., Chopra, M., and Hall, L. M. (1995). Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function. Cell 82, 1001-1011.
    • (1995) Cell , vol.82 , pp. 1001-1011
    • Feng, G.1    Deák, P.2    Chopra, M.3    Hall, L.M.4
  • 20
    • 0036338783 scopus 로고    scopus 로고
    • Evolution of voltage-gated Na(+) channels
    • Goldin, A. L. (2002). Evolution of voltage-gated Na(+) channels. J Exp Biol 205, 575-584.
    • (2002) J Exp Biol , vol.205 , pp. 575-584
    • Goldin, A.L.1
  • 21
    • 0031860262 scopus 로고    scopus 로고
    • Functional anatomy of scorpion toxins affecting sodium channels
    • Gordon, D., Savarin, P., Gurevitz, M., and Zinn-Justin, S. (1998). Functional anatomy of scorpion toxins affecting sodium channels. J Toxicol Toxin Rev 2, 131-159.
    • (1998) J Toxicol Toxin Rev , vol.2 , pp. 131-159
    • Gordon, D.1    Savarin, P.2    Gurevitz, M.3    Zinn-Justin, S.4
  • 22
    • 0036709305 scopus 로고    scopus 로고
    • An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch
    • Goudet, C., Chi, C. W., and Tytgat, J. (2002). An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch. Toxicon 40, 1239-1258.
    • (2002) Toxicon , vol.40 , pp. 1239-1258
    • Goudet, C.1    Chi, C.W.2    Tytgat, J.3
  • 23
    • 79251581335 scopus 로고    scopus 로고
    • Localization of receptor site on insect sodium channel for depressant β-toxin BmK IT2
    • He, H., Liu, Z., Dong, B., Zhang, J., Shu, X., Zhou, J., and Ji, Y. (2011). Localization of receptor site on insect sodium channel for depressant β-toxin BmK IT2. PLoS ONE 6, e14510.
    • (2011) PLoS ONE , vol.6
    • He, H.1    Liu, Z.2    Dong, B.3    Zhang, J.4    Shu, X.5    Zhou, J.6    Ji, Y.7
  • 24
    • 77957890721 scopus 로고    scopus 로고
    • Molecular determination of selectivity of the site 3 modulator (BmK I) to sodium channels in the CNS: a clue to the importance of Nav1.6 in BmK I-induced neuronal hyperexcitability
    • He, H., Liu, Z., Dong, B., Zhou, J., Zhu, H., and Ji, Y. (2010). Molecular determination of selectivity of the site 3 modulator (BmK I) to sodium channels in the CNS: a clue to the importance of Nav1. 6 in BmK I-induced neuronal hyperexcitability. Biochem J 431, 289-298.
    • (2010) Biochem J , vol.431 , pp. 289-298
    • He, H.1    Liu, Z.2    Dong, B.3    Zhou, J.4    Zhu, H.5    Ji, Y.6
  • 25
    • 0032987061 scopus 로고    scopus 로고
    • Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch
    • Ji, Y. H., Li, Y. J., Zhang, J. W., Song, B. L., Yamaki, T., Mochizuki, T., Hoshino, M., and Yanaihara, N. (1999). Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch. Toxicon 37, 519-536.
    • (1999) Toxicon , vol.37 , pp. 519-536
    • Ji, Y.H.1    Li, Y.J.2    Zhang, J.W.3    Song, B.L.4    Yamaki, T.5    Mochizuki, T.6    Hoshino, M.7    Yanaihara, N.8
  • 26
    • 79957823703 scopus 로고    scopus 로고
    • The study of sodium channels involved in pain responses using specific modulators
    • Ji, Y. H., and Liu, T. (2008). The study of sodium channels involved in pain responses using specific modulators. Sheng Li Xue Bao 60, 628-634.
    • (2008) Sheng Li Xue Bao , vol.60 , pp. 628-634
    • Ji, Y.H.1    Liu, T.2
  • 27
    • 0030247156 scopus 로고    scopus 로고
    • Two neurotoxins (BmK I and BmK II) from the venom of the scorpion Buthus martensi Karsch: purification, amino acid sequences and assessment of specific activity
    • Ji, Y. H., Mansuelle, P., Terakawa, S., Kopeyan, C., Yanaihara, N., Hsu, K., and Rochat, H. (1996). Two neurotoxins (BmK I and BmK II) from the venom of the scorpion Buthus martensi Karsch: purification, amino acid sequences and assessment of specific activity. Toxicon 34, 987-1001.
    • (1996) Toxicon , vol.34 , pp. 987-1001
    • Ji, Y.H.1    Mansuelle, P.2    Terakawa, S.3    Kopeyan, C.4    Yanaihara, N.5    Hsu, K.6    Rochat, H.7
  • 28
    • 43949151999 scopus 로고
    • Amino acid sequence of an excitatory insect-selective toxin (BmK IT) from venom of the scorpion Buthus martensi Karsch
    • Ji, Y. H., Mansuelle, P., Xu, K., Granier, C., Kopeyan, C., Terakawa, S., and Rochat, H. (1994). Amino acid sequence of an excitatory insect-selective toxin (BmK IT) from venom of the scorpion Buthus martensi Karsch. Sci China B 37, 42-49.
    • (1994) Sci China B , vol.37 , pp. 42-49
    • Ji, Y.H.1    Mansuelle, P.2    Xu, K.3    Granier, C.4    Kopeyan, C.5    Terakawa, S.6    Rochat, H.7
  • 29
    • 0036842070 scopus 로고    scopus 로고
    • The binding of BmK abT, a unique neurotoxin, to mammal brain and insect Na (+) channels using biosensor
    • Ji, Y. H., Wang, W. X., Wang, Q., and Huang, Y. P. (2002). The binding of BmK abT, a unique neurotoxin, to mammal brain and insect Na (+) channels using biosensor. Eur J Pharmacol 454, 25-30.
    • (2002) Eur J Pharmacol , vol.454 , pp. 25-30
    • Ji, Y.H.1    Wang, W.X.2    Wang, Q.3    Huang, Y.P.4
  • 30
    • 0033988420 scopus 로고    scopus 로고
    • Characterization of four distinct monoclonal antibodies specific to BmK AS-1, a novel scorpion bioactive polypeptide
    • Jia, L. Y., Xie, H. F., and Ji, Y. H. (2000). Characterization of four distinct monoclonal antibodies specific to BmK AS-1, a novel scorpion bioactive polypeptide. Toxicon 38, 605-617.
    • (2000) Toxicon , vol.38 , pp. 605-617
    • Jia, L.Y.1    Xie, H.F.2    Ji, Y.H.3
  • 31
    • 0032744565 scopus 로고    scopus 로고
    • Biosensor binding assay of BmK AS-1, a novel Na + channel-blocking scorpion ligand on rat brain synaptosomes
    • Jia, L. Y., Zhang, J. W., and Ji, Y. H. (1999). Biosensor binding assay of BmK AS-1, a novel Na + channel-blocking scorpion ligand on rat brain synaptosomes. Neuroreport 10, 3359-3362.
    • (1999) Neuroreport , vol.10 , pp. 3359-3362
    • Jia, L.Y.1    Zhang, J.W.2    Ji, Y.H.3
  • 32
    • 0030963793 scopus 로고    scopus 로고
    • Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains
    • Kontis, K. J., Rounaghi, A., and Goldin, A. L. (1997). Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains. J Gen Physiol 110, 391-401.
    • (1997) J Gen Physiol , vol.110 , pp. 391-401
    • Kontis, K.J.1    Rounaghi, A.2    Goldin, A.L.3
  • 33
    • 0031766356 scopus 로고    scopus 로고
    • The myth of scorpion suicide: are scorpions insensitive to their own venom?
    • Legros, C., Martin-Eauclaire, M. F., and Cattaert, D. (1998). The myth of scorpion suicide: are scorpions insensitive to their own venom? J Exp Biol 201, 2625-2636.
    • (1998) J Exp Biol , vol.201 , pp. 2625-2636
    • Legros, C.1    Martin-Eauclaire, M.F.2    Cattaert, D.3
  • 34
    • 33745228127 scopus 로고    scopus 로고
    • Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3
    • Leipold, E., Hansel, A., Borges, A., and Heinemann, S. H. (2006). Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3. Mol Pharmacol 70, 340-347.
    • (2006) Mol Pharmacol , vol.70 , pp. 340-347
    • Leipold, E.1    Hansel, A.2    Borges, A.3    Heinemann, S.H.4
  • 35
    • 1342287128 scopus 로고    scopus 로고
    • Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3
    • Leipold, E., Lu, S., Gordon, D., Hansel, A., and Heinemann, S. H. (2004). Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3. Mol Pharmacol 65, 685-691.
    • (2004) Mol Pharmacol , vol.65 , pp. 685-691
    • Leipold, E.1    Lu, S.2    Gordon, D.3    Hansel, A.4    Heinemann, S.H.5
  • 36
    • 0033776481 scopus 로고    scopus 로고
    • Binding characteristics of BmK I, an alphalike scorpion neurotoxic polypeptide, on cockroach nerve cord synaptosomes
    • Li, Y. J., and Ji, Y. H. (2000). Binding characteristics of BmK I, an alphalike scorpion neurotoxic polypeptide, on cockroach nerve cord synaptosomes. J Pept Res 56, 195-200.
    • (2000) J Pept Res , vol.56 , pp. 195-200
    • Li, Y.J.1    Ji, Y.H.2
  • 37
    • 0034283841 scopus 로고    scopus 로고
    • BmK AS: new scorpion neurotoxin binds to distinct receptor sites of mammal and insect voltage-gated sodium channels
    • Li, Y. J., Liu, Y., and Ji, Y. H. (2000a). BmK AS: new scorpion neurotoxin binds to distinct receptor sites of mammal and insect voltage-gated sodium channels. J Neurosci Res 61, 541-548.
    • (2000) J Neurosci Res , vol.61 , pp. 541-548
    • Li, Y.J.1    Liu, Y.2    Ji, Y.H.3
  • 38
    • 0033735270 scopus 로고    scopus 로고
    • The binding of BmK IT2, a depressant insect-selective scorpion toxin on mammal and insect sodium channels
    • Li, Y. J., Tan, Z. Y., and Ji, Y. H. (2000b). The binding of BmK IT2, a depressant insect-selective scorpion toxin on mammal and insect sodium channels. Neurosci Res 38, 257-264.
    • (2000) Neurosci Res , vol.38 , pp. 257-264
    • Li, Y.J.1    Tan, Z.Y.2    Ji, Y.H.3
  • 39
    • 0035957731 scopus 로고    scopus 로고
    • Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach
    • Liu, Z., Chung, I., and Dong, K. (2001). Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach. Insect Biochem Mol Biol 31, 703-713.
    • (2001) Insect Biochem Mol Biol , vol.31 , pp. 703-713
    • Liu, Z.1    Chung, I.2    Dong, K.3
  • 40
    • 0024976602 scopus 로고
    • Molecular analysis of the para locus, a sodium channel gene in Drosophila
    • Loughney, K., Kreber, R., and Ganetzky, B. (1989). Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell 58, 1143-1154.
    • (1989) Cell , vol.58 , pp. 1143-1154
    • Loughney, K.1    Kreber, R.2    Ganetzky, B.3
  • 41
    • 84894404731 scopus 로고    scopus 로고
    • The domain 4 S3-S4 extracellular loop provides molecular determinants for binding of -scorpion toxins (LqhII, and LqhIT) to the voltage-gated rat skeletal muscle Na + channel (rSkM1)
    • Ma Z., T. L., Lu S., Kong J., Gordon D., Kallen R. G., (2000). The domain 4 S3-S4 extracellular loop provides molecular determinants for binding of -scorpion toxins (LqhII, and LqhIT) to the voltage-gated rat skeletal muscle Na + channel (rSkM1). Biophys Soc Abstract.
    • (2000) Biophys Soc Abstract
    • Ma, Z.T.L.1    Lu, S.2    Kong, J.3    Gordon, D.4    Kallen, R.G.5
  • 42
    • 0026512959 scopus 로고
    • Tissue-specific expression of the voltagesensitive sodium channel
    • Mandel, G. (1992). Tissue-specific expression of the voltagesensitive sodium channel. J Membr Biol 125, 193-205.
    • (1992) J Membr Biol , vol.125 , pp. 193-205
    • Mandel, G.1
  • 43
    • 26844487463 scopus 로고    scopus 로고
    • Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels
    • Mantegazza, M., and Cestèle, S. (2005). Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels. J Physiol 568, 13-30.
    • (2005) J Physiol , vol.568 , pp. 13-30
    • Mantegazza, M.1    Cestèle, S.2
  • 44
    • 0031881488 scopus 로고    scopus 로고
    • Independent versus coupled inactivation in sodium channels. Role of the domain 2 S4 segment
    • Mitrovic, N., George, A. L. Jr, and Horn, R. (1998). Independent versus coupled inactivation in sodium channels. Role of the domain 2 S4 segment. J Gen Physiol 111, 451-462.
    • (1998) J Gen Physiol , vol.111 , pp. 451-462
    • Mitrovic, N.1    George Jr., A.L.2    Horn, R.3
  • 45
    • 0024580682 scopus 로고
    • Two sodium-channel genes in Drosophila: implications for channel diversity
    • Ramaswami, M., and Tanouye, M. A. (1989). Two sodium-channel genes in Drosophila: implications for channel diversity. Proc Natl Acad Sci USA 86, 2079-2082.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2079-2082
    • Ramaswami, M.1    Tanouye, M.A.2
  • 46
    • 0037109221 scopus 로고    scopus 로고
    • Na(v)1.5 underlies the 'third TTX-R sodium current' in rat small DRG neurons
    • Renganathan, M., Dib-Hajj, S., and Waxman, S. G. (2002). Na(v)1. 5 underlies the 'third TTX-R sodium current' in rat small DRG neurons. Brain Res Mol Brain Res 106, 70-82.
    • (2002) Brain Res Mol Brain Res , vol.106 , pp. 70-82
    • Renganathan, M.1    Dib-Hajj, S.2    Waxman, S.G.3
  • 47
    • 0342263396 scopus 로고
    • Molecular cloning of a putative tetrodotoxin-resistant rat heart Na + channel isoform
    • Rogart, R. B., Cribbs, L. L., Muglia, L. K., Kephart, D. D., and Kaiser, M. W. (1989). Molecular cloning of a putative tetrodotoxin-resistant rat heart Na + channel isoform. Proc Natl Acad Sci USA 86, 8170-8174.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8170-8174
    • Rogart, R.B.1    Cribbs, L.L.2    Muglia, L.K.3    Kephart, D.D.4    Kaiser, M.W.5
  • 48
    • 0030037704 scopus 로고    scopus 로고
    • Molecular determinants of high affinity binding of alphascorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na + channel alpha subunit
    • Rogers, J. C., Qu, Y., Tanada, T. N., Scheuer, T., and Catterall, W. A. (1996). Molecular determinants of high affinity binding of alphascorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na + channel alpha subunit. J Biol Chem 271, 15950-15962.
    • (1996) J Biol Chem , vol.271 , pp. 15950-15962
    • Rogers, J.C.1    Qu, Y.2    Tanada, T.N.3    Scheuer, T.4    Catterall, W.A.5
  • 49
    • 0031252098 scopus 로고    scopus 로고
    • The L1014F point mutation in the house fly Vssc1 sodium channel confers knockdown resistance to pyrethroids
    • Smith, T. J., Lee, S. H., Ingles, P. J., Knipple, D. C., and Soderlund, D. M. (1997). The L1014F point mutation in the house fly Vssc1 sodium channel confers knockdown resistance to pyrethroids. Insect Biochem Mol Biol 27, 807-812.
    • (1997) Insect Biochem Mol Biol , vol.27 , pp. 807-812
    • Smith, T.J.1    Lee, S.H.2    Ingles, P.J.3    Knipple, D.C.4    Soderlund, D.M.5
  • 50
    • 0037793247 scopus 로고    scopus 로고
    • The molecular biology of knockdown resistance to pyrethroid insecticides
    • Soderlund, D. M., and Knipple, D. C. (2003). The molecular biology of knockdown resistance to pyrethroid insecticides. Insect Biochem Mol Biol 33, 563-577.
    • (2003) Insect Biochem Mol Biol , vol.33 , pp. 563-577
    • Soderlund, D.M.1    Knipple, D.C.2
  • 51
    • 0036663011 scopus 로고    scopus 로고
    • Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels
    • Tan, J., Liu, Z., Nomura, Y., Goldin, A. L., and Dong, K. (2002a). Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels. J Neurosci 22, 5300-5309.
    • (2002) J Neurosci , vol.22 , pp. 5300-5309
    • Tan, J.1    Liu, Z.2    Nomura, Y.3    Goldin, A.L.4    Dong, K.5
  • 52
    • 0036009128 scopus 로고    scopus 로고
    • Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin
    • Tan, J., Liu, Z., Tsai, T. D., Valles, S. M., Goldin, A. L., and Dong, K. (2002b). Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin. Insect Biochem Mol Biol 32, 445-454.
    • (2002) Insect Biochem Mol Biol , vol.32 , pp. 445-454
    • Tan, J.1    Liu, Z.2    Tsai, T.D.3    Valles, S.M.4    Goldin, A.L.5    Dong, K.6
  • 53
    • 13444251644 scopus 로고    scopus 로고
    • Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding
    • Tan, J., Liu, Z., Wang, R., Huang, Z. Y., Chen, A. C., Gurevitz, M., and Dong, K. (2005). Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. Mol Pharmacol 67, 513-522.
    • (2005) Mol Pharmacol , vol.67 , pp. 513-522
    • Tan, J.1    Liu, Z.2    Wang, R.3    Huang, Z.Y.4    Chen, A.C.5    Gurevitz, M.6    Dong, K.7
  • 54
    • 0035130455 scopus 로고    scopus 로고
    • The inhibitory effects of BmK IT2, a scorpion neurotoxin on rat nociceptive flexion reflex and a possible mechanism for modulating voltage-gated Na(+) channels
    • Tan, Z. Y., Xiao, H., Mao, X., Wang, C. Y., Zhao, Z. Q., and Ji, Y. H. (2001). The inhibitory effects of BmK IT2, a scorpion neurotoxin on rat nociceptive flexion reflex and a possible mechanism for modulating voltage-gated Na(+) channels. Neuropharmacology 40, 352-357.
    • (2001) Neuropharmacology , vol.40 , pp. 352-357
    • Tan, Z.Y.1    Xiao, H.2    Mao, X.3    Wang, C.Y.4    Zhao, Z.Q.5    Ji, Y.H.6
  • 55
    • 0024240855 scopus 로고
    • Site of covalent attachment of alpha-scorpion toxin derivatives in domain I of the sodium channel alpha subunit
    • Tejedor, F. J., and Catterall, W. A. (1988). Site of covalent attachment of alpha-scorpion toxin derivatives in domain I of the sodium channel alpha subunit. Proc Natl Acad Sci USA 85, 8742-8746.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8742-8746
    • Tejedor, F.J.1    Catterall, W.A.2
  • 56
    • 0024518713 scopus 로고
    • Lack of effect of a neurotoxin from the scorpion Buthus martensi Karsch on nerve fibers of this scorpion
    • Terakawa, S., Kimura, Y., Hsu, K., and Ji, Y. H. (1989). Lack of effect of a neurotoxin from the scorpion Buthus martensi Karsch on nerve fibers of this scorpion. Toxicon 27, 569-578.
    • (1989) Toxicon , vol.27 , pp. 569-578
    • Terakawa, S.1    Kimura, Y.2    Hsu, K.3    Ji, Y.H.4
  • 57
    • 0028218019 scopus 로고
    • Developmentally regulated alternative splicing generates a complex array of Drosophila para sodium channel isoforms
    • Thackeray, J. R., and Ganetzky, B. (1994). Developmentally regulated alternative splicing generates a complex array of Drosophila para sodium channel isoforms. J Neurosci 14, 2569-2578.
    • (1994) J Neurosci , vol.14 , pp. 2569-2578
    • Thackeray, J.R.1    Ganetzky, B.2
  • 58
    • 0024811112 scopus 로고
    • Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology
    • Thomsen, W. J., and Catterall, W. A. (1989). Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology. Proc Natl Acad Sci USA 86, 10161-10165.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 10161-10165
    • Thomsen, W.J.1    Catterall, W.A.2
  • 60
    • 2342527262 scopus 로고    scopus 로고
    • Localization of voltage-gated ion channels in mammalian brain
    • Trimmer, J. S., and Rhodes, K. J. (2004). Localization of voltage-gated ion channels in mammalian brain. Annu Rev Physiol 66, 477-519.
    • (2004) Annu Rev Physiol , vol.66 , pp. 477-519
    • Trimmer, J.S.1    Rhodes, K.J.2
  • 61
    • 0038643783 scopus 로고    scopus 로고
    • Molecular characterization of an arachnid sodium channel gene from the varroa mite (Varroa destructor)
    • Wang, R., Huang, Z. Y., and Dong, K. (2003). Molecular characterization of an arachnid sodium channel gene from the varroa mite (Varroa destructor). Insect Biochem Mol Biol 33, 733-739.
    • (2003) Insect Biochem Mol Biol , vol.33 , pp. 733-739
    • Wang, R.1    Huang, Z.Y.2    Dong, K.3
  • 63
    • 33746531727 scopus 로고    scopus 로고
    • Comparative pharmacology and cloning of two novel arachnid sodium channels: Exploring the adaptive insensitivity of scorpion to its toxins
    • Zuo, X. P., He, H. Q., He, M., Liu, Z. R., Xu, Q., Ye, J. G., and Ji, Y. H. (2006). Comparative pharmacology and cloning of two novel arachnid sodium channels: Exploring the adaptive insensitivity of scorpion to its toxins. FEBS Lett 580, 4508-4514.
    • (2006) FEBS Lett , vol.580 , pp. 4508-4514
    • Zuo, X.P.1    He, H.Q.2    He, M.3    Liu, Z.R.4    Xu, Q.5    Ye, J.G.6    Ji, Y.H.7
  • 64
    • 15244363044 scopus 로고    scopus 로고
    • Molecular mechanism of scorpion neurotoxins acting on sodium channels: insight into their diverse selectivity
    • Zuo, X. P., and Ji, Y. H. (2004). Molecular mechanism of scorpion neurotoxins acting on sodium channels: insight into their diverse selectivity. Mol Neurobiol 30, 265-278.
    • (2004) Mol Neurobiol , vol.30 , pp. 265-278
    • Zuo, X.P.1    Ji, Y.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.