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Volumn 34, Issue 14, 2014, Pages 1853-1864

Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CURCUMIN; DACARBAZINE; FOSB PROTEIN, HUMAN; GRN PROTEIN, HUMAN; JUNB PROTEIN, HUMAN; PROTEIN C FOS; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TEMOZOLOMIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

EID: 84899599523     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.92     Document Type: Article
Times cited : (53)

References (49)
  • 2
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009; 10: 459-466.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    Van Den Bent, M.J.4    Taphoorn, M.J.5    Janzer, R.C.6
  • 3
    • 84862925785 scopus 로고    scopus 로고
    • Temozolomide: Mechanisms of action, repair and resistance
    • Zhang J, Stevens MF, Bradshaw TD. Temozolomide: mechanisms of action, repair and resistance. Curr Mol Pharmacol 2012; 5: 102-114.
    • (2012) Curr Mol Pharmacol , vol.5 , pp. 102-114
    • Zhang, J.1    Stevens, M.F.2    Bradshaw, T.D.3
  • 5
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 2004; 64: 7011-7021.
    • (2004) Cancer Res , vol.64 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3    Cipelletti, B.4    Gritti, A.5    De Vitis, S.6
  • 7
    • 44649137314 scopus 로고    scopus 로고
    • CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors
    • Beier D, Wischhusen J, Dietmaier W, Hau P, Proescholdt M, Brawanski A et al. CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors. Brain Pathol 2008; 18: 370-377.
    • (2008) Brain Pathol , vol.18 , pp. 370-377
    • Beier, D.1    Wischhusen, J.2    Dietmaier, W.3    Hau, P.4    Proescholdt, M.5    Brawanski, A.6
  • 9
    • 44849083591 scopus 로고    scopus 로고
    • Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma
    • Rebetz J, Tian D, Persson A, Widegren B, Salford LG, Englund E et al. Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma. PLoS ONE 2008; 3: e1936.
    • (2008) PLoS ONE , vol.3 , pp. 1936
    • Rebetz, J.1    Tian, D.2    Persson, A.3    Widegren, B.4    Salford, L.G.5    Englund, E.6
  • 11
    • 60149107175 scopus 로고    scopus 로고
    • Nestin and CD133: Valuable stem cell-specific markers for determining clinical outcome of glioma patients
    • Zhang M, Song T, Yang L, Chen R, Wu L, Yang Z et al. Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients. J Exp Clin Cancer Res 2008; 27: 85.
    • (2008) J Exp Clin Cancer Res , vol.27 , pp. 85
    • Zhang, M.1    Song, T.2    Yang, L.3    Chen, R.4    Wu, L.5    Yang, Z.6
  • 12
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444: 756-760.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6
  • 13
    • 36248961179 scopus 로고    scopus 로고
    • Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma
    • Kang MK, Kang SK. Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma. Stem Cell Dev 2007; 16: 837-847.
    • (2007) Stem Cell Dev , vol.16 , pp. 837-847
    • Kang, M.K.1    Kang, S.K.2
  • 14
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
    • Liu G, Yuan X, Zeng Z, Tunici P, Ng H, Abdulkadir IR et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer 2006; 5: 67.
    • (2006) Mol Cancer , vol.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3    Tunici, P.4    Ng, H.5    Abdulkadir, I.R.6
  • 15
    • 45949101159 scopus 로고    scopus 로고
    • Expression of multidrug resistance genes in normal and cancer stem cells
    • Shervington A, Lu C. Expression of multidrug resistance genes in normal and cancer stem cells. Cancer Investig 2008; 26: 535-542.
    • (2008) Cancer Investig , vol.26 , pp. 535-542
    • Shervington, A.1    Lu, C.2
  • 16
    • 0031854765 scopus 로고    scopus 로고
    • Granulins: The structure and function of an emerging family of growth factors
    • Bateman A, Bennett HP. Granulins: the structure and function of an emerging family of growth factors. J Endocrinol 1998; 158: 145-151.
    • (1998) J Endocrinol , vol.158 , pp. 145-151
    • Bateman, A.1    Bennett, H.P.2
  • 17
    • 0025133297 scopus 로고
    • Epithelins 1 and 2: Isolation and characterization of two cysteine-rich growth-modulating proteins
    • Shoyab M, McDonald VL, Byles C, Todaro GJ, Plowman GD. Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins. Proc Natl Acad Sci USA 1990; 87: 7912-7916.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7912-7916
    • Shoyab, M.1    McDonald, V.L.2    Byles, C.3    Todaro, G.J.4    Plowman, G.D.5
  • 18
    • 0035570226 scopus 로고    scopus 로고
    • Expression of progranulin and the epithelin/granulin precursor acrogranin correlates with neoplastic state in renal epithelium
    • Donald CD, Laddu A, Chandham P, Lim SD, Cohen C, Amin M et al. Expression of progranulin and the epithelin/granulin precursor acrogranin correlates with neoplastic state in renal epithelium. Anticancer Res 2001; 21: 3739-3742.
    • (2001) Anticancer Res , vol.21 , pp. 3739-3742
    • Donald, C.D.1    Laddu, A.2    Chandham, P.3    Lim, S.D.4    Cohen, C.5    Amin, M.6
  • 19
    • 0034163549 scopus 로고    scopus 로고
    • Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption
    • Liau LM, Lallone RL, Seitz RS, Buznikov A, Gregg JP, Kornblum HI et al. Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption. Cancer Res 2000; 60: 1353-1360.
    • (2000) Cancer Res , vol.60 , pp. 1353-1360
    • Liau, L.M.1    Lallone, R.L.2    Seitz, R.S.3    Buznikov, A.4    Gregg, J.P.5    Kornblum, H.I.6
  • 20
    • 12144287050 scopus 로고    scopus 로고
    • PC cell-derived growth factor expression in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
    • Pan CX, Kinch MS, Kiener PA, Langermann S, Serrero G, Sun L et al. PC cell-derived growth factor expression in prostatic intraepithelial neoplasia and prostatic adenocarcinoma. Clin Cancer Res 2004; 10: 1333-1337.
    • (2004) Clin Cancer Res , vol.10 , pp. 1333-1337
    • Pan, C.X.1    Kinch, M.S.2    Kiener, P.A.3    Langermann, S.4    Serrero, G.5    Sun, L.6
  • 21
    • 0344586759 scopus 로고    scopus 로고
    • Expression of PC-cell-derived growth factor in benign and malignant human breast epithelium
    • Serrero G, Ioffe OB. Expression of PC-cell-derived growth factor in benign and malignant human breast epithelium. Human Pathol 2003; 34: 1148-1154.
    • (2003) Human Pathol , vol.34 , pp. 1148-1154
    • Serrero, G.1    Ioffe, O.B.2
  • 22
    • 78650511134 scopus 로고    scopus 로고
    • Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance
    • Cheung ST, Cheung PF, Cheng CK, Wong NC, Fan ST. Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance. Gastroenterology 2011; 140: 344-355.
    • (2011) Gastroenterology , vol.140 , pp. 344-355
    • Cheung, S.T.1    Cheung, P.F.2    Cheng, C.K.3    Wong, N.C.4    Fan, S.T.5
  • 23
    • 84867996771 scopus 로고    scopus 로고
    • Progranulin overexpression predicts overall survival in patients with glioblastoma
    • Wang M, Li G, Yin J, Lin T, Zhang J. Progranulin overexpression predicts overall survival in patients with glioblastoma. Med Oncol 2012; 29: 2423-2431.
    • (2012) Med Oncol , vol.29 , pp. 2423-2431
    • Wang, M.1    Li, G.2    Yin, J.3    Lin, T.4    Zhang, J.5
  • 24
    • 1842865745 scopus 로고    scopus 로고
    • Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
    • Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y, Kondo S. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 2004; 11: 448-457.
    • (2004) Cell Death Differ , vol.11 , pp. 448-457
    • Kanzawa, T.1    Germano, I.M.2    Komata, T.3    Ito, H.4    Kondo, Y.5    Kondo, S.6
  • 25
    • 34347221946 scopus 로고    scopus 로고
    • Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors
    • Dhandapani KM, Mahesh VB, Brann DW. Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors. J Neurochem 2007; 102: 522-538.
    • (2007) J Neurochem , vol.102 , pp. 522-538
    • Dhandapani, K.M.1    Mahesh, V.B.2    Brann, D.W.3
  • 26
    • 84855170282 scopus 로고    scopus 로고
    • Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism
    • Frampton G, Invernizzi P, Bernuzzi F, Pae HY, Quinn M, Horvat D et al. Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism. Gut 2012; 61: 268-277.
    • (2012) Gut , vol.61 , pp. 268-277
    • Frampton, G.1    Invernizzi, P.2    Bernuzzi, F.3    Pae, H.Y.4    Quinn, M.5    Horvat, D.6
  • 27
    • 84855400983 scopus 로고    scopus 로고
    • Progranulin stimulated by LPA promotes the migration of aggressive breast cancer cells
    • Swamydas M, Nguyen D, Allen LD, Eddy J, Dreau D. Progranulin stimulated by LPA promotes the migration of aggressive breast cancer cells. Cell Commun Adhesion 2011; 18: 119-130.
    • (2011) Cell Commun Adhesion , vol.18 , pp. 119-130
    • Swamydas, M.1    Nguyen, D.2    Allen, L.D.3    Eddy, J.4    Dreau, D.5
  • 28
    • 84875018599 scopus 로고    scopus 로고
    • Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma
    • Barazzuol L, Jena R, Burnet NG, Meira LB, Jeynes JC, Kirkby KJ et al. Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma. Radiat Oncol 2013; 8: 65.
    • (2013) Radiat Oncol , vol.8 , pp. 65
    • Barazzuol, L.1    Jena, R.2    Burnet, N.G.3    Meira, L.B.4    Jeynes, J.C.5    Kirkby, K.J.6
  • 29
    • 34547451145 scopus 로고    scopus 로고
    • Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
    • Garcia-Alloza M, Borrelli LA, Rozkalne A, Hyman BT, Bacskai BJ. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J Neurochem 2007; 102: 1095-1104.
    • (2007) J Neurochem , vol.102 , pp. 1095-1104
    • Garcia-Alloza, M.1    Borrelli, L.A.2    Rozkalne, A.3    Hyman, B.T.4    Bacskai, B.J.5
  • 30
  • 31
    • 60849117508 scopus 로고    scopus 로고
    • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
    • Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 2009; 4: 226-235.
    • (2009) Cell Stem Cell , vol.4 , pp. 226-235
    • Bleau, A.M.1    Hambardzumyan, D.2    Ozawa, T.3    Fomchenko, E.I.4    Huse, J.T.5    Brennan, C.W.6
  • 32
    • 77950838848 scopus 로고    scopus 로고
    • A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha
    • Seidel S, Garvalov BK, Wirta V, von Stechow L, Schanzer A, Meletis K et al. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain 2010; 133: 983-995.
    • (2010) Brain , vol.133 , pp. 983-995
    • Seidel, S.1    Garvalov, B.K.2    Wirta, V.3    Von Stechow, L.4    Schanzer, A.5    Meletis, K.6
  • 34
    • 2642526992 scopus 로고    scopus 로고
    • The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
    • Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE et al. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem 2004; 279: 24218-24225.
    • (2004) J Biol Chem , vol.279 , pp. 24218-24225
    • Krishnamurthy, P.1    Ross, D.D.2    Nakanishi, T.3    Bailey-Dell, K.4    Zhou, S.5    Mercer, K.E.6
  • 35
    • 77950231070 scopus 로고    scopus 로고
    • CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma
    • Xu Y, Stamenkovic I, Yu Q. CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma. Cancer Res 2010; 70: 2455-2464.
    • (2010) Cancer Res , vol.70 , pp. 2455-2464
    • Xu, Y.1    Stamenkovic, I.2    Yu, Q.3
  • 36
    • 0035161545 scopus 로고    scopus 로고
    • AP-1 and heat shock protein 27 expression in human astrocytomas
    • Assimakopoulou M, Varakis J. AP-1 and heat shock protein 27 expression in human astrocytomas. J Cancer Res Clin Oncol 2001; 127: 727-732.
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 727-732
    • Assimakopoulou, M.1    Varakis, J.2
  • 37
    • 78751552841 scopus 로고    scopus 로고
    • Fos-related antigen 1 (Fra-1) pairing with and transactivation of JunB in GBM cells
    • Debinski W, Gibo DM. Fos-related antigen 1 (Fra-1) pairing with and transactivation of JunB in GBM cells. Cancer Biol Ther 2011; 11: 254-262.
    • (2011) Cancer Biol Ther , vol.11 , pp. 254-262
    • Debinski, W.1    Gibo, D.M.2
  • 38
    • 84883055248 scopus 로고    scopus 로고
    • Involvement of FOS-mediated miR-181b/miR-21 signalling in the progression of malignant gliomas
    • Tao T, Wang Y, Luo H, Yao L, Wang L, Wang J et al. Involvement of FOS-mediated miR-181b/miR-21 signalling in the progression of malignant gliomas. Eur J Cancer 2013; 49: 3055-3063.
    • (2013) Eur J Cancer , vol.49 , pp. 3055-3063
    • Tao, T.1    Wang, Y.2    Luo, H.3    Yao, L.4    Wang, L.5    Wang, J.6
  • 39
    • 34548737197 scopus 로고    scopus 로고
    • The genetics of frontotemporal lobar degeneration
    • Rademakers R, Hutton M. The genetics of frontotemporal lobar degeneration. Curr Neurol Neurosci Rep 2007; 7: 434-442.
    • (2007) Curr Neurol Neurosci Rep , vol.7 , pp. 434-442
    • Rademakers, R.1    Hutton, M.2
  • 41
    • 84877099960 scopus 로고    scopus 로고
    • Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice
    • Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G et al. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. J Neurosci 2013; 33: 5352-5361.
    • (2013) J Neurosci , vol.33 , pp. 5352-5361
    • Filiano, A.J.1    Martens, L.H.2    Young, A.H.3    Warmus, B.A.4    Zhou, P.5    Diaz-Ramirez, G.6
  • 42
    • 0033668411 scopus 로고    scopus 로고
    • Synergistic action of genistein and cisplatin on growth inhibition and cytotoxicity of human medulloblastoma cells
    • Khoshyomn S, Manske GC, Lew SM, Wald SL, Penar PL. Synergistic action of genistein and cisplatin on growth inhibition and cytotoxicity of human medulloblastoma cells. Pediatr Neurosurg 2000; 33: 123-131.
    • (2000) Pediatr Neurosurg , vol.33 , pp. 123-131
    • Khoshyomn, S.1    Manske, G.C.2    Lew, S.M.3    Wald, S.L.4    Penar, P.L.5
  • 43
    • 84876800051 scopus 로고    scopus 로고
    • The Aurora kinases inhibitor VE-465 is a novel treatment for glioblastoma multiforme
    • Lee PY, Chen CL, Lin ZZ, Cheng AL, Chen EI, Whang-Peng J et al. The Aurora kinases inhibitor VE-465 is a novel treatment for glioblastoma multiforme. Oncology 2013; 84: 326-335.
    • (2013) Oncology , vol.84 , pp. 326-335
    • Lee, P.Y.1    Chen, C.L.2    Lin, Z.Z.3    Cheng, A.L.4    Chen, E.I.5    Whang-Peng, J.6
  • 44
    • 84877738261 scopus 로고    scopus 로고
    • A comparative study of primary and recurrent human glioblastoma multiforme using the small animal imaging and molecular expressive profiles
    • Lin LT, Chiou SH, Lee TW, Liu RS, Hwang JJ, Chang CH et al. A comparative study of primary and recurrent human glioblastoma multiforme using the small animal imaging and molecular expressive profiles. Mol Imaging Biol 2013; 15: 262-272.
    • (2013) Mol Imaging Biol , vol.15 , pp. 262-272
    • Lin, L.T.1    Chiou, S.H.2    Lee, T.W.3    Liu, R.S.4    Hwang, J.J.5    Chang, C.H.6
  • 45
    • 84877766516 scopus 로고    scopus 로고
    • Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu EGF, and TNF-alpha in breast cancer
    • Jin L, Wessely O, Marcusson EG, Ivan C, Calin GA, Alahari SK. Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-alpha in breast cancer. Cancer Res 2013; 73: 2884-2896.
    • (2013) Cancer Res , vol.73 , pp. 2884-2896
    • Jin, L.1    Wessely, O.2    Marcusson, E.G.3    Ivan, C.4    Calin, G.A.5    Alahari, S.K.6
  • 47
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996; 183: 1797-1806.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 48
    • 77951689083 scopus 로고    scopus 로고
    • Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells
    • Lee PC, Kakadiya R, Su TL, Lee TC. Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells. Neoplasia 2010; 12: 376-387.
    • (2010) Neoplasia , vol.12 , pp. 376-387
    • Lee, P.C.1    Kakadiya, R.2    Su, T.L.3    Lee, T.C.4


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