Synergistic action of genistein and cisplatin on growth inhibition and cytotoxicity of human medulloblastoma cells

Pediatric Neurosurgery

Volumn 33, Issue 3, 2000, Pages 123-131

  Khoshyomn, Sami ^a   Manske, Gregory C ^a   Lew, Sean M ^a   Wald, Steven L ^b   Penar, Paul L ^a,c  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF VERMONT   (United States)

Author keywords

Cisplatin; Genistein; Medulloblastoma; Synergism; Vincristine

Indexed keywords

AGAROSE; CISPLATIN; GENISTEIN; ISOFLAVONE DERIVATIVE; VINCRISTINE;

APOPTOSIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; PRIORITY JOURNAL; SCHOOL CHILD; SOYBEAN; TREATMENT OUTCOME;

EID: 0033668411     PISSN: 10162291     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028993     Document Type: Article

References (42)

1. Oski's pediatrics
2. Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia
3. Second malignancies in young children with primary brain tumors following treatment with prolonged postoperative chemotherapy and delayed irradiation: A pediatric oncology group study
4. Cisplatin pharmacokinetics in children with cancer
5. Prevention of precancerous colonic lesions in rats by soy flakes, soy flour, genistein, and calcium
6. Genistein, a specific inhibitor of tyrosine-specific protein kinases
7. Effect of genistein on in vitro and in vivo models of cancer
8. Diadzein is a more bioavailable soymilk isoflavone than is genistein in adult women
9. Genistein, a dietary-derived inhibitor of in vitro angiogenesis
10. Effect of genistein on topoisomerase activity and on the growth of [Val12] Haras-transformed NIH 3T3 cells
11. Evaluation of the biochemical targets of genistein in tumor cells
12. Purification of motility factor (GMF) from human malignant glioma cells and its biological significance in tumor invasion
13. Soybeans inhibit mammary tumors in models of breast cancer
14. Dietary genistein: Perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat
15. Anti-invasive activity of 3,7-dimethoxyflavone in vitro
16. Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of brain
17. The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells
18. Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinase
19. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides
20. Anti-proliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract
21. Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life
22. Exposure of infants to phyto-oestrogens from soy-based infant formula
23. Tamoxifen and genistein synergistically down-regulate signal transduction and proliferation in estrogen receptor-negative human breast carcinoma MDA-MB-435 cells
24. The role of the epidermal growth factor receptor in human gliomas. I. The control of cell growth
25. Analysis of apoptosis by laser scanning cytometry
26. Transforming growth factor-alpha immunoreactivity in adult rat brain
27. Soyfoods, isoflavones and risk of colonic cancer: A review of the in vitro and in vivo data
28. Soy intake and cancer risk: A review of the in vitro and in vivo data
29. Dietary fiber, phytoestrogens and breast cancer risk
30. Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: Evidence for distinct drug interaction domains on topoisomerase II
31. Genistein alters the ontogeny of mammary cancer development and protects against mammary cancer in rats
32. Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g baked soybean powder (kinako)
33. Synergistic action of tiazofurin and genistein on growth inhibition and differentiation of K-562 human leukemic cells
34. Synergistic action of tiazofurin and genistein in human ovarian carcinoma cells
35. Antiproliferative effect of genistein and Adriamycin against estrogen-dependent and -independent human breast carcinoma cell lines
36. Genistein modulates neuroblastoma cell proliferation and differentiation through induction of apoptosis and regulation of tyrosine kinase activity and N-myc expression
37. Receptor tyrosine kinase inhibition suppresses growth of pediatric renal tumor cells in vitro
38. Inhibitors for protein tyrosine kinases, erbstatin, genistein and herbimycin A, induce differentiation of human neural tumor cell lines
39. Soy proteins for the prevention and treatment of children with cow's milk allergy
40. Phyto-oestrogens in soy-based infant formula
41. Tolerance of soy formulas with reduced phytate/phytoestrogens fed to healthy, term infants
42. Soybean isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis