Transient receptor potential melastatin 8 channel inhibition potentiates the hypothermic response to transient receptor potential vanilloid 1 activation in the conscious mouse

Critical Care Medicine

Volumn 42, Issue 5, 2014, Pages

  Feketa, Viktor V ^a   Zhang, Yi ^b   Cao, Zhijuan ^a   Balasubramanian, Adithya ^a   Flores, Christopher M ^c   Player, Mark R ^c   Marrelli, Sean P ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

dihydrocapsaicin; pharmacological hypothermia; thermoregulation; transient receptor potential; transient receptor potential melastatin 8 (TRPM8); transient receptor potential vanilloid 1 (TRPV1)

Indexed keywords

DIHYDROCAPSAICIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLD EXPOSURE; CONTINUOUS INFUSION; CONTROLLED STUDY; CORE TEMPERATURE; DOSE RESPONSE; HYPOTHERMIA; INDUCED HYPOTHERMIA; LOADING DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPEATED DRUG DOSE; THERMOREGULATION;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; BENZIMIDAZOLES; BODY TEMPERATURE REGULATION; CAPSAICIN; DISEASE MODELS, ANIMAL; HYPOTHERMIA, INDUCED; ISOXAZOLES; MALE; MICE; MICE, INBRED C57BL; TRPM CATION CHANNELS; TRPV CATION CHANNELS;

EID: 84899586729     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000229     Document Type: Article

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