메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

Post-translational decrease in respiratory chain proteins in the polg mutator mouse brain

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MESSENGER RNA; MITOCHONDRIAL PROTEIN; RESPIRATORY CHAIN PROTEIN; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; MITOCHONDRIAL DNA; POLG PROTEIN, MOUSE;

EID: 84899574732     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094646     Document Type: Article
Times cited : (12)

References (20)
  • 1
    • 84874591240 scopus 로고    scopus 로고
    • The role of mitochondria in aging
    • doi:10.1172/JCI64125
    • Bratic A, Larsson N-G (2013) The role of mitochondria in aging. J Clin Invest 123: 951-957. doi:10.1172/JCI64125.
    • (2013) J Clin Invest , vol.123 , pp. 951-957
    • Bratic, A.1    Larsson, N.-G.2
  • 2
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • DOI 10.1038/nrg1606
    • Taylor RW, Turnbull DM (2005) MITOCHONDRIAL DNA MUTATIONS IN HUMAN DISEASE. Nat Rev Genet 6: 389-402. doi:10.1038/nrg1606. (Pubitemid 40577182)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.5 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 7
    • 78649499624 scopus 로고    scopus 로고
    • The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers
    • doi:10.1016/j.cmet.2010.11.012
    • Williams SL, Huang J, Edwards YJ, Ulloa RH, Dillon LM, et al. (2010) The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers. Cell Metab 12: 675-682. doi:10.1016/j.cmet.2010.11. 012.
    • (2010) Cell Metab , vol.12 , pp. 675-682
    • Williams, S.L.1    Huang, J.2    Edwards, Y.J.3    Ulloa, R.H.4    Dillon, L.M.5
  • 8
    • 68049115765 scopus 로고    scopus 로고
    • Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice
    • doi:10.1016/j.cmet.2009.06.010
    • Edgar D, Shabalina I, Camara Y, Wredenberg A, Calvaruso MA, et al. (2009) Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice. Cell Metab 10: 131-138. doi:10.1016/j.cmet.2009.06.010.
    • (2009) Cell Metab , vol.10 , pp. 131-138
    • Edgar, D.1    Shabalina, I.2    Camara, Y.3    Wredenberg, A.4    Calvaruso, M.A.5
  • 9
    • 67651177611 scopus 로고    scopus 로고
    • Do mtDNA deletions drive premature aging in mtDNA mutator mice?
    • doi:10.1111/j.1474-9726.2009.00484.x
    • Kraytsberg Y, Simon DK, Turnbull DM, Khrapko K (2009) Do mtDNA deletions drive premature aging in mtDNA mutator mice? Aging Cell 8: 502-506. doi:10.1111/j.1474-9726.2009.00484.x.
    • (2009) Aging Cell , vol.8 , pp. 502-506
    • Kraytsberg, Y.1    Simon, D.K.2    Turnbull, D.M.3    Khrapko, K.4
  • 12
    • 84855417557 scopus 로고    scopus 로고
    • Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice
    • doi:10.1016/j.cmet.2011.11.012
    • Ahlqvist KJ, Hämäläinen RH, Yatsuga S, Uutela M, Terzioglu M, et al. (2012) Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice. Cell Metab 15: 100-109. doi:10.1016/j.cmet.2011.11.012.
    • (2012) Cell Metab , vol.15 , pp. 100-109
    • Ahlqvist, K.J.1    Hämäläinen, R.H.2    Yatsuga, S.3    Uutela, M.4    Terzioglu, M.5
  • 13
    • 78650533229 scopus 로고    scopus 로고
    • High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio
    • doi:10.1073/pnas.1008189107
    • Ross JM, Öberg J, Brené S, Coppotelli G, Terzioglu M, et al. (2010) High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio. Proc Natl Acad Sci 107: 20087-20092. doi:10.1073/pnas.1008189107.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 20087-20092
    • Ross, J.M.1    Öberg, J.2    Brené, S.3    Coppotelli, G.4    Terzioglu, M.5
  • 14
    • 79952753140 scopus 로고    scopus 로고
    • Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
    • doi:10.1073/pnas.1019581108
    • Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, et al. (2011) Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proc Natl Acad Sci U S A 108: 4135-4140. doi:10.1073/pnas.1019581108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4135-4140
    • Safdar, A.1    Bourgeois, J.M.2    Ogborn, D.I.3    Little, J.P.4    Hettinga, B.P.5
  • 15
    • 77955380974 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice
    • doi:10.1371/journal.pone.0011468
    • Hiona A, Sanz A, Kujoth GC, Pamplona R, Seo AY, et al. (2010) Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. PloS One 5: e11468. doi:10.1371/journal.pone.0011468.
    • (2010) PloS One , vol.5
    • Hiona, A.1    Sanz, A.2    Kujoth, G.C.3    Pamplona, R.4    Seo, A.Y.5
  • 16
    • 84875664276 scopus 로고    scopus 로고
    • mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex
    • doi:10.1038/nn.3332
    • Dillman AA, Hauser DN, Gibbs JR, Nalls MA, McCoy MK, et al. (2013) mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci 16: 499-506. doi:10.1038/nn.3332.
    • (2013) Nat Neurosci , vol.16 , pp. 499-506
    • Dillman, A.A.1    Hauser, D.N.2    Gibbs, J.R.3    Nalls, M.A.4    McCoy, M.K.5
  • 17
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • doi:10.1186/gb-2010-11-10-r106
    • Anders S, Huber W (2010) Differential expression analysis for sequence count data. Genome Biol 11: R106. doi:10.1186/gb-2010-11-10-r106.
    • (2010) Genome Biol , vol.11
    • Anders, S.1    Huber, W.2
  • 18
    • 84865527768 scopus 로고    scopus 로고
    • Detecting differential usage of exons from RNA-seq data
    • doi:10.1101/gr.133744.111
    • Anders S, Reyes A, Huber W (2012) Detecting differential usage of exons from RNA-seq data. Genome Res 22: 2008-2017. doi:10.1101/gr.133744.111.
    • (2012) Genome Res , vol.22 , pp. 2008-2017
    • Anders, S.1    Reyes, A.2    Huber, W.3
  • 19
    • 84879879014 scopus 로고    scopus 로고
    • Variation and genetic control of protein abundance in humans
    • Wu L, Candille SI, Choi Y, Xie D, Jiang L, et al. (2013) Variation and genetic control of protein abundance in humans. Nature 499: 79-82.
    • (2013) Nature , vol.499 , pp. 79-82
    • Wu, L.1    Candille, S.I.2    Choi, Y.3    Xie, D.4    Jiang, L.5
  • 20
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • doi:10.1038/nprot.2008.211
    • Huang DW, Sherman BT, Lempicki RA (2008) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57. doi:10.1038/nprot.2008.211.
    • (2008) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.