Genotypes of Klebsiella oxytoca isolates from patients with nosocomial pneumonia are distinct from those of isolates from patients with antibiotic-associated hemorrhagic colitis

Journal of Clinical Microbiology

Volumn 52, Issue 5, 2014, Pages 1607-1616

  Herzog, Kathrin A T ^a   Schneditz, Georg ^b   Leitner, Eva ^a   Feierl, Gebhard ^a   Hoffmann, Karl Martin ^a   Zollner Schwetz, Ines ^a   Krause, Robert ^a   Gorkiewicz, Gregor ^a   Zechner, Ellen L ^b   Högenauer, Christoph ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; GLUCOSE 6 PHOSPHATE ISOMERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MALATE DEHYDROGENASE; RNA POLYMERASE BETA SUBUNIT; ANTIINFECTIVE AGENT;

ANTIBIOTIC ASSOCIATED HEMORRHAGIC COLITIS; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; GAPA GENE; GENE CLUSTER; GENE TRANSFER; GENETIC VARIABILITY; GENOTYPE; HEMORRHAGIC COLITIS; HOSPITAL ACQUIRED PNEUMONIA; HOUSEKEEPING GENE; HUMAN; INFB GENE; INTESTINE; KLEBSIELLA OXYTOCA; MDH GENE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PGI GENE; PHOE GENE; PHYLOGENETIC TREE; PRIORITY JOURNAL; RESPIRATORY SYSTEM; RPOB GENE; TONB GENE; TOXIN SYNTHESIS; ANTIBIOTIC RESISTANCE; CLASSIFICATION; CROSS INFECTION; DRUG EFFECTS; ENTEROCOLITIS, PSEUDOMEMBRANOUS; GENETICS; KLEBSIELLA INFECTIONS; MICROBIOLOGY; MULTIGENE FAMILY; PHYLOGENY; PNEUMONIA; PROCEDURES; RESPIRATORY TRACT INFECTIONS;

ANTI-BACTERIAL AGENTS; CROSS INFECTION; CYTOTOXINS; DRUG RESISTANCE, BACTERIAL; ENTEROCOLITIS, PSEUDOMEMBRANOUS; GENOTYPE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA OXYTOCA; MULTIGENE FAMILY; MULTILOCUS SEQUENCE TYPING; PHYLOGENY; PNEUMONIA; RESPIRATORY TRACT INFECTIONS;

EID: 84899501136     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.03373-13     Document Type: Article

References (40)

1. Beaugerie L, Metz M, Barbut F, Bellaiche G, Bouhnik Y, Raskine L, Nicolas JC, Chatelet FP, Lehn N, Petit JC, Infectious Colitis Study Group. 2003. Klebsiella oxytoca as an agent of antibiotic-associated hemorrhagic colitis. Clin. Gastroenterol. Hepatol. 1:370-376. http://dx.doi.org/10.1053/S1542-3565 (03) 00183-6.
2. Högenauer C, Langner C, Beubler E, Lippe IT, Schicho R, Gorkiewicz G, Krause R, Gerstgrasser N, Krejs GJ, Hinterleitner TA. 2006. Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis. N. Engl. J. Med. 355:2418-2426. http://dx.doi.org/10.1056/NEJMoa 054765.
3. Zollner-Schwetz I, Högenauer C, Joainig M, Weberhofer P, Gorkiewicz G, Valentin T, Hinterleitner TA, Krause R. 2008. Role of Klebsiella oxytoca in antibiotic-associated diarrhea. Clin. Infect. Dis. 47:e74-e78. http://dx.doi.org/10.1086/592074.
4. Dethlefsen L, Relman DA. 2011. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc. Natl. Acad. Sci. U. S. A. 108(Suppl 1):4554-4561. http://dx.doi.org/10.1073/pnas.1000087107.
5. Walker AW, Ince J, Duncan SH, Webster LM, Holtrop G, Ze X, Brown D, Stares MD, Scott P, Bergerat A, Louis P, McIntosh F, Johnstone AM, Lobley GE, Parkhill J, Flint HJ. 2011. Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J. 5:220-230. http://dx.doi.org/10. 1038/ismej.2010.118.
6. Joainig MM, Gorkiewicz G, Leitner E, Weberhofer P, Zollner-Schwetz I, Lippe I, Feierl G, Krause R, Hinterleitner T, Zechner EL, Hogenauer C. 2010. Cytotoxic effects of Klebsiella oxytoca strains isolated from patients with antibiotic-associated hemorrhagic colitis or other diseases caused by infections and from healthy subjects. J. Clin. Microbiol. 48:817-824. http://dx.doi.org/ 10.1128/JCM.01741-09.
7. Sievert DM, Ricks P, Edwards JR, Schneider A, Patel J, Srinivasan A, Kallen A, Limbago B, Fridkin S, National Healthcare Safety Network (NHSN) Team and Participating NHSN Families. 2013. Antimicrobialresistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010. Infect. Control Hosp Epidemiol. 34:1-14. http://dx.doi.org/10.1086/668770.
8. Molton JS, Tambyah PA, Ang BS, Ling ML, Fisher DA. 2013. The global spread of healthcare-associated multidrug-resistant bacteria: a perspective from Asia. Clin. Infect. Dis. 56:1310-1318. http://dx.doi.org/10.1093/cid/cit020.
9. Brisse S, Grimont F, Grimont PD. 2006. The genus Klebsiella, p 159-196. In Dworkin M, Falkow S, Rosenberg E, Schleifer KH, Stackebrandt E (ed), The prokaryotes. Springer, New York, NY.
10. Polage CR, Solnick JV, Cohen SH. 2012. Nosocomial diarrhea: evaluation and treatment of causes other than Clostridium difficile. Clin. Infect. Dis. 55:982-989. http://dx.doi.org/10.1093/cid/cis551.
11. Podschun R, Ullmann U. 1998. Klebsiella spp as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin. Microbiol. Rev. 11:589-603.
12. Sbrana F, Malacarne P, Viaggi B, Costanzo S, Leonetti P, Leonildi A, Casini B, Tascini C, Menichetti F. 2013. Carbapenem-sparing antibiotic regimens for infections caused by Klebsiella pneumoniae carbapenemaseproducing K. pneumoniae in intensive care unit. Clin. Infect. Dis. 56:697-700. http://dx.doi.org/10.1093/cid/cis969.
13. Cheng VC, Yam WC, Tsang LL, Yau MC, Siu GK, Wong SC, Chan JF, To KK, Tse H, Hung IF, Tai JW, Ho PL, Yuen KY. 2012. Epidemiology of Klebsiella oxytoca-associated diarrhea detected by Simmons citrate agar supplemented with inositol, tryptophan, and bile salts. J. Clin. Microbiol. 50:1571-1579. http://dx.doi.org/10.1128/JCM.00163-12.
14. Higaki M, Chida T, Takano H, Nakaya R. 1990. Cytotoxic component (s) of Klebsiella oxytoca on HEp-2 cells. Microbiol. Immunol. 34:147-151. http://dx.doi.org/10.1111/j.1348-0421.1990.tb00999.x.
15. Minami J, Katayama S, Matsushita O, Sakamoto H, Okabe A. 1994. Enterotoxic activity of Klebsiella oxytoca cytotoxin in rabbit intestinal loops. Infect. Immun. 62:172-177.
16. Urwin R, Maiden MC. 2003. Multi-locus sequence typing: a tool for global epidemiology. Trends Microbiol. 11:479-487. http://dx.doi.org/10.1016/j.tim. 2003.08.006.
17. Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S. 2005. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J. Clin. Microbiol. 43:4178-4182. http://dx.doi.org/10.1128/JCM.43.8.417 8-4182.2005.
18. Hunter PR, Gaston MA. 1988. Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. J. Clin. Microbiol. 26:2465-2466.
19. Jolley KA, Maiden MC. 2010. BIGSdb: scalable analysis of bacterial genome variation at the population level. BMC Bioinformatics 11:595. http://dx.doi.org/10.1186/1471-2105-11-595.
20. Librado P, Rozas J. 2009. DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. Bioinformatics 25:1451-1452. http://dx.doi.org/10. 1093/bioinformatics/btp187.
21. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. 2011. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28:2731-2739. http://dx.doi.org/10.1093/molbev/msr121.
22. Feil EJ, Li BC, Aanensen DM, Hanage WP, Spratt BG. 2004. eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J. Bacteriol. 186:1518-1530. http://dx.doi.org/10.1128/JB.186.5.1518-1530.2004.
23. Huson DH, Bryant D. 2006. Application of phylogenetic networks in evolutionary studies. Mol. Biol. Evol. 23:254-267. http://dx.doi.org/10.1093/ molbev/msj030.
24. Haubold B, Hudson RR. 2000. LIAN 3.0: detecting linkage disequilibrium in multilocus data. Bioinformatics 16:847-849. http://dx.doi.org/10.1093/ bioinformatics/16.9.847.
25. Deguchi T, Yasuda M, Kawamura T, Nakano M, Ozeki S, Kanematsu E, Nishino Y, Kawada Y. 1997. Improved antimicrobial activity of DU-6859a, a new fluoroquinolone, against quinolone-resistant Klebsiella pneumoniae and Enterobacter cloacae isolates with alterations in GyrA and ParC proteins. Antimicrob. Agents Chemother. 41:2544-2546.
26. Brisse S, Verhoef J. 2001. Phylogenetic diversity of Klebsiella pneumoniae and Klebsiella oxytoca clinical isolates revealed by randomly amplified polymorphic DNA, gyrA and parC genes sequencing and automated ribotyping. Int. J. Syst. Evol. Microbiol. 51:915-924. http://dx.doi.org/10. 1099/00207713-51-3-915.
27. Nemoy LL, Kotetishvili M, Tigno J, Keefer-Norris A, Harris AD, Perencevich EN, Johnson JA, Torpey D, Sulakvelidze A, Morris JG, Jr, Stine OC. 2005. Multilocus sequence typing versus pulsed-field gel electrophoresis for characterization of extended-spectrum beta-lactamaseproducing Escherichia coli isolates. J. Clin. Microbiol. 43:1776-1781. http://dx.doi.org/10.1128/JCM.43.4. 1776-1781.2005.
28. Liu WB, Liu B, Zhu XN, Yu SJ, Shi XM. 2011. Diversity of Salmonella isolates using serotyping and multilocus sequence typing. Food Microbiol. 28:1182-1189. http://dx.doi.org/10.1016/j.fm.2011.04.001.
29. Maiden MC. 2006. Multilocus sequence typing of bacteria. Annu. Rev. Microbiol. 60:561-588. http://dx.doi.org/10.1146/annurev. micro.59.030 804.121325.
30. Clermont O, Olier M, Hoede C, Diancourt L, Brisse S, Keroudean M, Glodt J, Picard B, Oswald E, Denamur E. 2011. Animal and human pathogenic Escherichia coli strains share common genetic backgrounds. Infect. Genet. Evol. 11:654-662. http://dx.doi.org/10.1016/j.meegid.2011.02.005.
31. Le Gall T, Clermont O, Gouriou S, Picard B, Nassif X, Denamur E, Tenaillon O. 2007. Extraintestinal virulence is a coincidental by-product of commensalism in B2 phylogenetic group Escherichia coli strains. Mol. Biol. Evol. 24:2373-2384. http://dx.doi.org/10.1093/molbev/msm172.
32. Kallet RH, Quinn TE. 2005. The gastrointestinal tract and ventilator-associated pneumonia. Respir. Care. 50:910-921; discussion 921-923.
33. Hurley JC. 1995. Prophylaxis with enteral antibiotics in ventilated patients: selective decontamination or selective cross-infection? Antimicrob. Agents Chemother. 39:941-947. http://dx.doi.org/10.1128/AAC.39.4.941.
34. Rotstein C, Evans G, Born A, Grossman R, Light RB, Magder S, McTaggart B, Weiss K, Zhanel GG. 2008. Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults. Can. J. Infect. Dis. Med. Microbiol. 19:19-53.
35. Ramirez P, Bassi GL, Torres A. 2012. Measures to prevent nosocomial infections during mechanical ventilation. Curr. Opin. Crit. Care. 18:86-92. http://dx.doi.org/10.1097/MCC.0b013e32834ef3ff.
36. Bonten MJ, Krueger WA. 2006. Selective decontamination of the digestive tract: cumulating evidence, at last? Semin. Respir. Crit. Care Med. 27:18-22. http://dx.doi.org/10.1055/s-2006-933669.
37. Chaudhuri RR, Henderson IR. 2012. The evolution of the Escherichia coli phylogeny. Infect. Genet. Evol. 12:214-226. http://dx.doi.org/10.1016/j.meegid. 2012.01.005.
38. Schubert S, Darlu P, Clermont O, Wieser A, Magistro G, Hoffmann C, Weinert K, Tenaillon O, Matic I, Denamur E. 2009. Role of intraspecies recombination in the spread of pathogenicity islands within the Escherichia coli species. PLoS Pathog. 5:e1000257. http://dx.doi.org/10.1371/journal.ppat. 1000257.
39. Dobrindt U, Hochhut B, Hentschel U, Hacker J. 2004. Genomic islands in pathogenic and environmental microorganisms. Nat. Rev. Microbiol. 2:414-424. http://dx.doi.org/10.1038/nrmicro884.
40. Kyne L, Warny M, Qamar A, Kelly CP. 2000. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N. Engl. J. Med. 342:390-397. http://dx.doi.org/10.1056/NEJM2000021034 20604.