Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia

Journal of Neurochemistry

Volumn 129, Issue 4, 2014, Pages 683-695

  Jin, Ye ^a   Sato, Koichi ^a   Tobo, Ayaka ^a   Mogi, Chihiro ^a   Tobo, Masayuki ^a   Murata, Naoya ^a   Ishii, Satoshi ^b   Im, Dong Soon ^c   Okajima, Fumikazu ^a  

^a GUNMA UNIVERSITY   (Japan)

^b AKITA UNIVERSITY   (Japan)

^c Pusan National University   (South Korea)

Author keywords

acidification; cAMP; interleukin 1 ; microglia; protein kinase A; TDAG8

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TDAG8 PROTEIN; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BINDING SITE; CELL ACTIVITY; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MICROGLIA; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

MUS;

ACIDIFICATION; CAMP; INTERLEUKIN-1Β; MICROGLIA; PROTEIN KINASE A; TDAG8;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CELLS, CULTURED; COLFORSIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EXTRACELLULAR FLUID; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HYDROGEN-ION CONCENTRATION; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NF-KAPPA B; POLY I-C; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SECOND MESSENGER SYSTEMS;

EID: 84899493407     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12661     Document Type: Article

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