Met receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Pomerleau, Véronique ^a   Landry, Mélissa ^a   Bernier, Jimmy ^a   Vachon, Pierre H ^a   Saucier, Caroline ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Anoikis; Colorectal cancer; Grb2; Intestinal epithelial cell; MAPK; Met; PI3K; Proliferation; Receptor tyrosine kinase; Shc; Transformation

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SHC; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; SELUMETINIB; UVOMORULIN; CADHERIN; GRB2 PROTEIN, HUMAN; MET PROTEIN, HUMAN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANOIKIS; ARTICLE; CANCER GROWTH; CELL GROWTH; CELL SPREADING; CELL VIABILITY; COLON CARCINOGENESIS; CONTACT INHIBITION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; INTESTINE EPITHELIUM CELL; INTRACELLULAR SIGNALING; MALIGNANT TRANSFORMATION; METASTATIC COLORECTAL CANCER; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA INTERFERENCE; BIOSYNTHESIS; CELL LINE; CELL TRANSFORMATION; COLORECTAL NEOPLASMS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INTESTINE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

CADHERINS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; GRB2 ADAPTOR PROTEIN; HUMANS; INTESTINES; PROTO-ONCOGENE PROTEINS C-MET; SHC SIGNALING ADAPTOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 84899492741     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-240     Document Type: Article

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