A four-generation feeding study with genetically modified (Bt) maize in laying hens

Journal of Animal and Feed Sciences

Volumn 23, Issue 1, 2014, Pages 58-63

  Halle, I ^a   Flachowsky, G ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

GM maize; Growth; Hatchability; Laying performance; Poultry

Indexed keywords

EID: 84899488728     PISSN: 12301388     EISSN: None     Source Type: Journal    
DOI: 10.22358/jafs/65717/2014     Document Type: Article

References (42)

1. Antoniou M., Robinson C., Fagan J., 2012. GMO Myths and Truths. Earth Open Source. London, pp. 123
2. Baranowski A., Rosochacki S., Parada R., Jaszczak K., Zimny J., Potoszynowicz J., 2006. The effect of diet containing genetically modified triticale on growth and transgenic DNA fate in selected tissues of mice. Anim. Sci. Pap. Rep. 24, 129-142
3. Brake D.G., Evenson D.P., 2004. A generational study of glyphosatetolerant soybeans on mouse fetal, postnatal, pubertal and adult testicular development. Food Chem. Toxicol. 42, 29-36 (Pubitemid 37421323)
4. Brake D.G., Thaler R., Evenson D.P., 2004. Evaluation of Bt (Bacillus thunngiensis) com on mouse testicular development by dual parameter flow cytometry. J. Agr. Food Chem. 52, 2097-2102
5. Buzoianu S.G., Walsh M.C., Rea M.C. et al., 2012a. Effect of feeding Bt maize to sows during gestation and lactation on maternal and offspring immunity and fate of transgenic material. PLoS One 7, 10:e47851
6. Buzoianu S.G., Walsh M.C., Rea M.C., Cassidy J.P., Ryan T.P., Ross R.P., Gardiner G.E., Lawlor P.G., 2012b. Trans-generational effects of feeding genetically modified maize to nulliparous sows and offspring on offspring growth and health. J. Anim. Sci., published ahead of print October 24, 2012, doi:10.2527/ jas.2012-5360
7. Chassy B.M., 2010. Food safety and consumer health. New Biotechnol. 27, 534-544
8. Daleprane J.B., Pacheco J.T., Boaventura G.T., 2009b. Evaluation of protein quality from genetically modified and organic soybean in two consecutives generations of Wistar rats. Brazil Arch. Biol. Technol. 52, 841-847
9. EFSA (European Food Safety Agency), 2008. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials. Food Chem. Toxicol. 46, 2-70
10. EFSA, 2011. Guidance for risk assessment of food and feed from genetically modified plants. EFSA J. 9(5), 2150, pp. 37
11. FDA (Food and Drug Administration; Redbook), 2007. Guidance for Industry and other Stakeholders, Toxicological Principles for the Safety Assessment of Food Ingredients. July 2000; Revised July 2007; U.S. Department of Health and Human Services, Food and Drug Administration, Center for Food Safety and Applied Nutrition. http://www.cfsan.fda.aov/auidance.html
12. Flachowsky G. (Editor), 2013. Animal Nutrition with Transgenic Plants. CAB International. Wallingford (UK), pp. 234
13. Flachowsky G., Halle I., Aulrich K., 2005. Long term feeding of Btcom - a 10 generation study with quails. Arch. Anim. Nutr. 59, 449-451 (Pubitemid 41770212)
14. Flachowsky G., Schafft H., Meyer U., 2012. Animal feeding studies for nutritional and safety assessments of feeds from genetically modified plants: a review. J. Consum. Prot. Food Safety 7, 179-194
15. GfE (Gesellschaft für Emährungsphysiologle), 1999. Recommendations for Energy and Nutrient Requirements of Laying Hens and Broilers (in German). DLG-Veriag, Frankfurt, pp. 185
16. Halle I., Aulrich K., Flachowsky G., 2006. Four generations feeding GMO-com to laying hens. Proc. Soc. Nutr. Physiol. 15, 114
17. Haryu Y, Taguchi Y, Itakura E., Mikami O., Miura K., Saeki T., Nakajima Y, 2009. Long term biosafety assessment of a genetically modified (GM) plant: the genetically modified (GM) insect-resistant Bt11 com does not affect the performance of multi-generations or life span of mice. Plant Sci. J. 3, 49-53
18. ILSI, 2003. Best Practices for the Conduct of Animal Studies to Evaluate Crops Genetically Modified for Input Traits. International Life Sciences Institute. Washington, DC, pp. 62
19. ILSI, 2007. Best Practices for the Conduct of Animal Studies to Evaluate Crops Genetically Modified for Output Traits. International Life Sciences Institute. Washington, DC, pp. 194
20. James C., 2013. Global Status of Commercial Transgenic Crops: 2012. ISAAA, Ithaca, NY http://www.isaaa.org
21. Kiliç A., Akay M.T., 2008. A three-generation study with genetically modified Bt corn in rats: biochemical and histopathological investigation. Food Chem. Toxicol. 46, 1164-1170
22. Kleter G.A., Kok E.J., 2010. Safety assessment of biotechnology used in animal production, including genetically modified (GM) feed and GM animals-a review. Anim. Sci. Pap. Rep. 28, 105-114
23. Korwin-Kossakowska A., Sartowska K., Linkiewicz A., Tomczyk G., Prusak B., Sender G., 2013. Evaluation of the effect of genetically modified RR soya bean and MON 810 maize in the diet of Japanese quail on chosen aspects of their productivity and retention of transgenic DNA in tissues. Arch. Tierzucht 56, 60-70
24. Krzyzowska M., Wincenciak M., Winnicka A., Baranowski A., Jaszczak K., Zimny J., Niemiałtowski M., 2010. The effect of multigenerational diet containing genetically modified triticale on immune system in mice. Pol. J. Vet. Sci. 13, 423-430
25. OECD, 1993. Safety Evaluation of Foods Derived by Modern Biotechnology. Concepts and Principles. OECD, Paris (France)
26. Reuter T, Aulrich K., 2003. Investigations on genetically modified maize (Bt-maize) in pig nutrition: Fate of feed-ingested foreign DNA in pig bodies. Eur. Food Res. Technol. 216, 185-192
27. Rhee G.S., Cho D.H., Won Y.H. et al., 2005. Multigeneration reproductive and developmental toxicity study of bar gene inserted into genetically modified potato on rats. J. Toxicol. Env. Health A 68, 2263-2276
28. Ricroch A.E., Bernheim A., Snell C., Pascal G., Paris A., Kuntz M., 2013. Long-term and multigenerational feeding studies. In: G. Flachowsky G. (Editor) Animal Nutrition with Transgenic Plants. CAB International, pp. 112-129
29. Sartowska K., Korwin-Kossakowska A., Sender G., Jozwik A., Prokopiuk M., 2012. The impact of genetically modified plants in the diet of Japanese qails on performance traits and the nutritional value of meat and eggs - preliminary results. Arch. Geflügelk. 76, 140-144
30. SAS, 2002-2008. Institute Inc., SAS 9.2, Cary, NC
31. Séralini G.E., Clair E., Mesnage R., Grass S., Defarge N., Malatesta M., Hennequin D., Spiraux de Vendômois J., 2012. Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food Chem. Toxicol, http://dx.doi. org/10.1016/j.fct.2012.08.005 (visited on November 6, 2012)
32. Séralini G.-E., Mesnage R., Clair E., Grass S., Vendomois J.S.de, Cellier D., 2011. Genetically modified crops safety assessments: present limits and possible improvements. Environ. Sci. Eur. 23, 10
33. Snell C., Berheim A., Bergé J.B., Kuntz M., Pascal G., Paris A., Ricroch A., 2012. Assessment of the Health Impact of GE Plant Diets in Long Term and Multigenerational Animal Feeding Trials: a Literature Review. Food Chem. Toxicol. 50, 1134-1148
34. Trabalza-Marinucci M., Brandi G., Rondini C. et al., 2008. A three-year longitudinal study on the effects of a diet containing genetically modified Bt176 maize on the health status and performance of sheep. Livest. Sci. 113, 178-190
35. Tudisco R., Mastellone V, Cutrignelli M.I., Lombardi R, Bovera F., Mirabella N., Piccolo G., Calabro S., Avallone L, Infascelli F., 2010. Fate of transgenic DNA and evaluation of metabolic effects in goats fed genetically modified soybean and in their offsprings. Animal 4, 1662-1671
36. Tyshko N.V., Zhminchenko V.M., Pashorina V.A., Selyaskin K.E., Saprykin V.P., Utembaeva N.T., Tutelyan V.A., 2010. Assessment of the impact of GMO of plant origin on rat progeny development in 3 generations (in Russian). Probi. Nutr. 80(1), 14-28
37. Valenta H., Dänicke S., Wolff J., 2002. Comparison of a HPLC- and an ELISA-method for determination of deoxynivalenol in dust of mills, brans and cereals (in German), 114. VDLUFA-Kongressband, p. 255
38. Valenta H., Oldenburg E., 1995. Determination of zearalenon, alphazearalenon and alpha-zerealenol in maize silage with HPLC and GC/MS (in German). VDLUFA-Schriftenreihe 40/1995, 107 VDLUFA-Kongress, Garmisch-Partenkirchen, pp. 957 960
39. VDLUFA-Methodenbuch (Editor), 2012. Band III, 1976 bis 2007. Die chemische Untersuchung von Futtermitteln. 3. Auflage. Verband Deutscher Landwirtschaftlicher Untersuchungs- und Forschungsanstalten. VDLUFA (Editor), 3.-8.
40. × MON 810 fed in long term reproduction studies in mice. Research Report of Section IV, Vol. 1/2/2008 of the Bundesministerium für Gesundheit, Familie und Jugend. Vienna (Austria)
41. WPSA (World Poultry Science Association), 1984. The prediction of apparent metabolizable energy values for poultry in compound feeds. Working Group No. 2 - Nutrition. World Poultry Sci. J. 40, 181-182
42. Zhou X.H., Dong Y, Wang.Y, Xiao X., Xu Y, Xu B., Li X., Wei X.S., Liu Q.Q., 2012. A three generation study with high-lysine transgenie rice in Sprague-Dawley rats. Food Chem. Toxicol. 50, 1902-1910