Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth

Cancer Research

Volumn 70, Issue 17, 2010, Pages 6824-6836

  Lee, Syng Ook ^a   Abdelrahim, Maen ^b   Yoon, Kyungsil ^c   Chintharlapalli, Sudhakar ^a,e   Papineni, Sabitha ^a   Kim, Kyounghyun ^a   Wang, Huamin ^a   Safe, Stephen ^a,d  

^a UNIVERSITY OF TEXAS   (United States)

^b M D ANDERSON CANCER CENTER ORLANDO   (United States)

^c National Cancer Center   (South Korea)

^d TEXAS A AND M UNIVERSITY   (United States)

^e ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 BIS(3' INDOLYL) 1 (4 HYDROXYPHENYL)METHANE; ANTINEOPLASTIC AGENT; NUCLEAR RECEPTOR NUR77; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PROTEIN BCL 2; PROTEIN P300; SMALL INTERFERING RNA; SURVIVIN; UNCLASSIFIED DRUG; 1,1-BIS(3'-INDOLYL)-1-(4-HYDROXYPHENYL)METHANE; ANISOLE DERIVATIVE; BIRC5 PROTEIN, HUMAN; E1A ASSOCIATED P300 PROTEIN; EP300 PROTEIN, HUMAN; INDOLE DERIVATIVE; INHIBITOR OF APOPTOSIS PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NR4A1 PROTEIN, HUMAN; PHENOL DERIVATIVE; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE INACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; MALE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; TUMOR GROWTH; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BIOSYNTHESIS; CELL GROWTH; DRUG EFFECTS; DRUG SCREENING; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE; NUDE MOUSE; PANCREATIC NEOPLASMS; PATHOLOGY; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANIMALS; ANISOLES; APOPTOSIS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; E1A-ASSOCIATED P300 PROTEIN; GENE KNOCKDOWN TECHNIQUES; HUMANS; INDOLES; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; PANCREATIC NEOPLASMS; PHENOLS; RNA, SMALL INTERFERING; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77956295989     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1992     Document Type: Article

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