메뉴 건너뛰기




Volumn 446, Issue 4, 2014, Pages 959-964

The formation of brown adipose tissue induced by transgenic over-expression of PPARγ2

Author keywords

Brown adipose tissue; Over expression; PPAR 2; Transgenic mice; UCP1; White adipose tissue

Indexed keywords

BROWN ADIPOSE TISSUE; OVER-EXPRESSION; PPARΓ2; TRANSGENIC MICE; UCP1; WHITE ADIPOSE TISSUE;

EID: 84899473698     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.03.033     Document Type: Article
Times cited : (14)

References (45)
  • 1
    • 35348874911 scopus 로고    scopus 로고
    • Developmental origin of fat: Tracking obesity to its source
    • S. Gesta, Y.H. Tseng, and C.R. Kahn Developmental origin of fat: tracking obesity to its source Cell 131 2007 242 256
    • (2007) Cell , vol.131 , pp. 242-256
    • Gesta, S.1    Tseng, Y.H.2    Kahn, C.R.3
  • 2
    • 52649143796 scopus 로고    scopus 로고
    • Brown fat and skeletal muscle: Unlikely cousins?
    • S.R. Farmer Brown fat and skeletal muscle: unlikely cousins? Cell 134 2008 726 727
    • (2008) Cell , vol.134 , pp. 726-727
    • Farmer, S.R.1
  • 3
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: Function and physiological significance
    • B. Cannon, and J. Nedergaard Brown adipose tissue: function and physiological significance Physiol. Rev. 84 2004 277 359
    • (2004) Physiol. Rev. , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 5
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade-a unifying system for energy control
    • D. Carling The AMP-activated protein kinase cascade-a unifying system for energy control Trends Biochem. Sci. 29 2007 18 24
    • (2007) Trends Biochem. Sci. , vol.29 , pp. 18-24
    • Carling, D.1
  • 7
    • 0028092988 scopus 로고
    • Critical phosphorylation sites for acetyl-CoA carboxylase activity
    • J. Ha, S. Daniel, S.S. Broyles, and K.H. Kim Critical phosphorylation sites for acetyl-CoA carboxylase activity J. Biol. Chem. 269 1994 22162 22168
    • (1994) J. Biol. Chem. , vol.269 , pp. 22162-22168
    • Ha, J.1    Daniel, S.2    Broyles, S.S.3    Kim, K.H.4
  • 8
    • 0030795278 scopus 로고    scopus 로고
    • Review regulation of mammalian acetyl-coenzyme A carboxylase
    • K.H. Kim Review regulation of mammalian acetyl-coenzyme A carboxylase Annu. Rev. Nutr. 17 1997 77 99
    • (1997) Annu. Rev. Nutr. , vol.17 , pp. 77-99
    • Kim, K.H.1
  • 9
    • 0031438705 scopus 로고    scopus 로고
    • Cig30, a mouse member of a novel membrane protein gene family, is involved in the recruitment of brown adipose tissue
    • P. Tvrdik, A. Asadi, L.P. Kozak, J. Nedergaard, B. Cannon, and A. Jacobsson Cig30, a mouse member of a novel membrane protein gene family, is involved in the recruitment of brown adipose tissue J. Biol. Chem. 272 1997 31738 31746
    • (1997) J. Biol. Chem. , vol.272 , pp. 31738-31746
    • Tvrdik, P.1    Asadi, A.2    Kozak, L.P.3    Nedergaard, J.4    Cannon, B.5    Jacobsson, A.6
  • 10
    • 0022499231 scopus 로고
    • Brown adipose tissue uncoupling protein content in human infants, children and adults
    • M.E. Lean, W.P. James, G. Jennings, and P. Trayhurn Brown adipose tissue uncoupling protein content in human infants, children and adults Clin. Sci. 71 1986 291 297
    • (1986) Clin. Sci. , vol.71 , pp. 291-297
    • Lean, M.E.1    James, W.P.2    Jennings, G.3    Trayhurn, P.4
  • 12
    • 34547631960 scopus 로고    scopus 로고
    • Unexpected evidence for active brown adipose tissue in adult humans
    • J. Nedergaard, T. Bengtsson, and B. Cannon Unexpected evidence for active brown adipose tissue in adult humans Am. J. Physiol. 296 2007 444 452
    • (2007) Am. J. Physiol. , vol.296 , pp. 444-452
    • Nedergaard, J.1    Bengtsson, T.2    Cannon, B.3
  • 13
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • P. Puigserver, Z. Wu, C.W. Park, R. Graves, M. Wright, and B.M. Spiegelman A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis Cell 92 1998 829 839
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 14
    • 33751011308 scopus 로고    scopus 로고
    • PGC-1alpha: A key regulator of energy metabolism
    • H.Y. Liang, and W.F. Ward PGC-1alpha: a key regulator of energy metabolism Adv. Physiol. Educ. 30 2006 145 151
    • (2006) Adv. Physiol. Educ. , vol.30 , pp. 145-151
    • Liang, H.Y.1    Ward, W.F.2
  • 15
    • 0035851187 scopus 로고    scopus 로고
    • PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth
    • E.D. Rosen, and B.M. Spiegelman PPARγ: a nuclear regulator of metabolism, differentiation, and cell growth J. Biol. Chem. 276 2001 37731 37734
    • (2001) J. Biol. Chem. , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 16
    • 0029102676 scopus 로고
    • Structural organization of mouse peroxisome proliferator activated receptor γ (mPPARγ) gene: Alternative promoter use and different splicing yield two mPPARγ isoforms
    • Y. Zhu, C. Qi, and J.R. Korenbergetal Structural organization of mouse peroxisome proliferator activated receptor γ (mPPARγ) gene: alternative promoter use and different splicing yield two mPPARγ isoforms Proc. Natl. Acad. Sci. USA 92 1995 7921 7925
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7921-7925
    • Zhu, Y.1    Qi, C.2    Korenbergetal, J.R.3
  • 17
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPAR
    • M. Lehrke, and M.A. Lazar The many faces of PPAR Cell 123 2005 993 999
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 18
    • 0026093631 scopus 로고
    • The effect of CP-68772, athiazolidine derivative, on insulin sensitivity in lean and obese Zucker rats
    • L. Bowen, P.P. Steven, R. Stevenson, and C.I. Shulman The effect of CP-68772, athiazolidine derivative, on insulin sensitivity in lean and obese Zucker rats Metabolism 40 1991 1025 1030
    • (1991) Metabolism , vol.40 , pp. 1025-1030
    • Bowen, L.1    Steven, P.P.2    Stevenson, R.3    Shulman, C.I.4
  • 19
    • 0034064359 scopus 로고    scopus 로고
    • Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: Relation to insulin action
    • M. Loviscach, N. Rehman, L. Carter, S. Mudaliar, P. Mohadeen, T.P. Ciaraldi, J.H. Veerkamp, and R.R. Henry Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: relation to insulin action Diabetologia 43 2000 304 311
    • (2000) Diabetologia , vol.43 , pp. 304-311
    • Loviscach, M.1    Rehman, N.2    Carter, L.3    Mudaliar, S.4    Mohadeen, P.5    Ciaraldi, T.P.6    Veerkamp, J.H.7    Henry, R.R.8
  • 21
    • 0028871780 scopus 로고
    • Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha
    • E. Hu, P. Tontonoz, and B.M. Spiegelman Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha Proc. Natl. Acad. Sci. USA 92 1995 9856 9860
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9856-9860
    • Hu, E.1    Tontonoz, P.2    Spiegelman, B.M.3
  • 23
    • 0028972025 scopus 로고
    • 15-Deoxy-12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
    • B.M. Forman, P. Tontonoz, J. Chen, R.P. Brun, B.M. Spiegelman, and R.M. Evans 15-Deoxy-12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ Cell 83 1995 803 812
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 25
    • 84870365034 scopus 로고    scopus 로고
    • Ectopic overexpression of swine PPARγ2 upregulated adipocyte genes expression and triacylglycerol in skeletal muscle of mice
    • J.L. Huang, Y.Z. Xiong, T. Li, L. Zhang, Z.J. Zhang, B. Zuo, D.Q. Xu, and Z.Q. Ren Ectopic overexpression of swine PPARγ2 upregulated adipocyte genes expression and triacylglycerol in skeletal muscle of mice Transgenic Res. 21 2012 1311 1318
    • (2012) Transgenic Res. , vol.21 , pp. 1311-1318
    • Huang, J.L.1    Xiong, Y.Z.2    Li, T.3    Zhang, L.4    Zhang, Z.J.5    Zuo, B.6    Xu, D.Q.7    Ren, Z.Q.8
  • 26
    • 25844484021 scopus 로고    scopus 로고
    • Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance
    • B. Zhao, R.J. Wall, and J. Yang Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance Biochem. Biophys. Res. Commun. 337 2005 248 255
    • (2005) Biochem. Biophys. Res. Commun. , vol.337 , pp. 248-255
    • Zhao, B.1    Wall, R.J.2    Yang, J.3
  • 29
    • 40849086138 scopus 로고    scopus 로고
    • Enhanced muscle by myostatin propeptide increases adipose tissue adiponectin, PPAR-α and PPAR-γ expressions
    • S.T. Suzuki, B. Zhao, and J. Yang Enhanced muscle by myostatin propeptide increases adipose tissue adiponectin, PPAR-α and PPAR-γ expressions Biochem. Biophys. Res. Commun. 369 2008 767 773
    • (2008) Biochem. Biophys. Res. Commun. , vol.369 , pp. 767-773
    • Suzuki, S.T.1    Zhao, B.2    Yang, J.3
  • 30
    • 68849107400 scopus 로고    scopus 로고
    • C/EBPα and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptorγ agonists
    • C. Vernochet, S.B. Peres, K.E. Davis, M.E. McDonald, Q. Li, H. Wang, P.E. Scherer, and S.R. Farmer C/EBPα and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptorγ agonists Mol. Cell. Biol. 29 2009 4714 4728
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 4714-4728
    • Vernochet, C.1    Peres, S.B.2    Davis, K.E.3    McDonald, M.E.4    Li, Q.5    Wang, H.6    Scherer, P.E.7    Farmer, S.R.8
  • 32
    • 0033787068 scopus 로고    scopus 로고
    • Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice
    • B. Li, L.A. Nolte, J.S. Ju, D.H. Han, T. Coleman, J.O. Holloszy, and C.F. Semenkovich Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice Nat. Med. 6 2000 1115 1120
    • (2000) Nat. Med. , vol.6 , pp. 1115-1120
    • Li, B.1    Nolte, L.A.2    Ju, J.S.3    Han, D.H.4    Coleman, T.5    Holloszy, J.O.6    Semenkovich, C.F.7
  • 33
    • 79960480409 scopus 로고    scopus 로고
    • The implication of brown adipose tissue for humans
    • E. Ravussin, and J. Galgani The implication of brown adipose tissue for humans Annu. Rev. Nutr. 31 2011 33 47
    • (2011) Annu. Rev. Nutr. , vol.31 , pp. 33-47
    • Ravussin, E.1    Galgani, J.2
  • 34
    • 0030717887 scopus 로고    scopus 로고
    • Uncoupling protein gene quantification of expression levels in adipose tissues of obese and non-obese humans
    • H. Oberkofler, G. Dallinger, Y.M. Liu, E. Hell, F. Krempler, and W. Patsch Uncoupling protein gene quantification of expression levels in adipose tissues of obese and non-obese humans J. Lipid Res. 38 1997 2125 2133
    • (1997) J. Lipid Res. , vol.38 , pp. 2125-2133
    • Oberkofler, H.1    Dallinger, G.2    Liu, Y.M.3    Hell, E.4    Krempler, F.5    Patsch, W.6
  • 35
    • 36148944441 scopus 로고    scopus 로고
    • Norepinephrine and rosiglitazone synergistically induce Elovl3 expressionin brown adipocytes
    • J.A. Jörgensen, D. Zadravec, and A. Jacobsson Norepinephrine and rosiglitazone synergistically induce Elovl3 expressionin brown adipocytes Am. J. Physiol. Endocrinol. Metab. 293 2007 1159 1168
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293 , pp. 1159-1168
    • Jörgensen, J.A.1    Zadravec, D.2    Jacobsson, A.3
  • 39
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocrinol. Rev. 20 1999 649 688
    • (1999) Endocrinol. Rev. , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 40
    • 10744221610 scopus 로고    scopus 로고
    • Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis
    • M.A. Christoffolete1, C.G. Linardi, L. Jesus, K.N. Ebina, S.D. Carvalho, M.O. Ribeiro, R. Rabelo, C. Curcio, L. Martins, E.T. Kimura, and A.C. Bianco Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis Diabetes 53 2003 577 584
    • (2003) Diabetes , vol.53 , pp. 577-584
    • Christoffolete, M.A.1    Linardi, C.G.2    Jesus, L.3    Ebina, K.N.4    Carvalho, S.D.5    Ribeiro, M.O.6    Rabelo, R.7    Curcio, C.8    Martins, L.9    Kimura, E.T.10    Bianco, A.C.11
  • 42
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • B.B. Kahn, T. Alquier, D. Carling, and D.G. Hardie AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism Cell Metab. 1 2005 15 25
    • (2005) Cell Metab. , vol.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 43
    • 56449117024 scopus 로고    scopus 로고
    • AMPK: A metabolic gauge regulating whole-body energy homeostasis
    • R. Lage, C. Diéguez, A. Vidal-Puig, and M. López AMPK: a metabolic gauge regulating whole-body energy homeostasis Trends Mol. Med. 14 2008 539 549
    • (2008) Trends Mol. Med. , vol.14 , pp. 539-549
    • Lage, R.1    Diéguez, C.2    Vidal-Puig, A.3    López, M.4
  • 45
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1a
    • S. Jager, C. Handschin, J. St-Pierre, and B.M. Spiegelman AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1a Proc. Natl. Acad. Sci. USA 104 2007 12017 12022
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.