MiR-29b inhibits collagen maturation in hepatic stellate cells through down-regulating the expression of HSP47 and lysyl oxidase

Biochemical and Biophysical Research Communications

Volumn 446, Issue 4, 2014, Pages 940-944

  Zhang, Yifei ^a   Ghazwani, Mohammed ^a   Li, Jiang ^a   Sun, Ming ^b   Stolz, Donna B ^b   He, Fengtian ^c   Fan, Jie ^d   Xie, Wen ^a   Li, Song ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Extracellular matrix; Fibrosis; Heat shock protein 47; Lysyl oxidase; miR 29b

Indexed keywords

CARBON TETRACHLORIDE; COLLAGEN; HEAT SHOCK PROTEIN 47; MICRORNA 29B; PROTEIN LYSINE 6 OXIDASE; RNA; TRANSFORMING GROWTH FACTOR BETA;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CELL ACTIVATION; CELL MATURATION; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE DELETION; GENE OVEREXPRESSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; RNA ISOLATION; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION;

MUS; RATTUS;

EXTRACELLULAR MATRIX; FIBROSIS; HEAT SHOCK PROTEIN 47; LYSYL OXIDASE; MIR-29B;

3' UNTRANSLATED REGIONS; ANIMALS; CELL LINE; CELLS, CULTURED; COLLAGEN; DOWN-REGULATION; EXTRACELLULAR MATRIX; HEPATIC STELLATE CELLS; HSP47 HEAT-SHOCK PROTEINS; HUMANS; LIVER CIRRHOSIS; MALE; MICE; MICRORNAS; PROTEIN-LYSINE 6-OXIDASE; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84899471345     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.03.037     Document Type: Article

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