메뉴 건너뛰기




Volumn 69, Issue 1, 2014, Pages 141-149

Prolyl Hydroxylase Inhibitors Protect from the Bone Loss in Ovariectomy Rats by Increasing Bone Vascularity

Author keywords

Estrogen; Hypoxia inducible factor; Osteoblasts; Ovariectomy; Prolyl hydroxylase inhibitor

Indexed keywords

RATTUS;

EID: 84899460553     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-013-9780-8     Document Type: Article
Times cited : (39)

References (39)
  • 1
    • 0037673933 scopus 로고    scopus 로고
    • Control of osteoblast function and regulation of bone mass
    • Harada, S., & Rodan, G. A. (2003). Control of osteoblast function and regulation of bone mass. Nature, 423, 349-355.
    • (2003) Nature , vol.423 , pp. 349-355
    • Harada, S.1    Rodan, G.A.2
  • 2
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle, W. J., Simonet, W. S., & Lacey, D. L. (2003). Osteoclast differentiation and activation. Nature, 423, 337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 3
    • 0023276009 scopus 로고
    • Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study
    • Burkhardt, R., Kettner, G., Bohm, W., Schmidmeier, M., Schlag, R., Frisch, B., et al. (1987). Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: A comparative histomorphometric study. Bone, 8, 157-164.
    • (1987) Bone , vol.8 , pp. 157-164
    • Burkhardt, R.1    Kettner, G.2    Bohm, W.3    Schmidmeier, M.4    Schlag, R.5    Frisch, B.6
  • 4
    • 0034166650 scopus 로고    scopus 로고
    • The mechanism of coupling: A role for the vasculature
    • Parfitt, A. M. (2000). The mechanism of coupling: A role for the vasculature. Bone, 2000(26), 319-323.
    • (2000) Bone , vol.2000 , Issue.26 , pp. 319-323
    • Parfitt, A.M.1
  • 5
    • 0031024406 scopus 로고    scopus 로고
    • Bone mineral density and blood flow to the lower extremities: The study of osteoporotic fractures
    • Vogt, M. T., Cauley, J. A., Kuller, L. H., & Nevitt, M. C. (1997). Bone mineral density and blood flow to the lower extremities: The study of osteoporotic fractures. Journal of Bone and Mineral Research, 12, 283-289.
    • (1997) Journal of Bone and Mineral Research , vol.12 , pp. 283-289
    • Vogt, M.T.1    Cauley, J.A.2    Kuller, L.H.3    Nevitt, M.C.4
  • 7
    • 5644235491 scopus 로고    scopus 로고
    • Forearm endothelial function and bone mineral loss in postmenopausal women
    • Sanada, M., Taguchi, A., Higashi, Y., Tsuda, M., Kodama, I., Yoshizumi, M., et al. (2004). Forearm endothelial function and bone mineral loss in postmenopausal women. Atherosclerosis, 176, 387-392.
    • (2004) Atherosclerosis , vol.176 , pp. 387-392
    • Sanada, M.1    Taguchi, A.2    Higashi, Y.3    Tsuda, M.4    Kodama, I.5    Yoshizumi, M.6
  • 8
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L. (2003). Targeting HIF-1 for cancer therapy. Nature Reviews Cancer, 2003(3), 721-732.
    • (2003) Nature Reviews Cancer , vol.2003 , Issue.3 , pp. 721-732
    • Semenza, G.L.1
  • 9
    • 34249913494 scopus 로고    scopus 로고
    • The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development
    • Wang, Y., Wan, C., Deng, L., Liu, X., Cao, X., Gilbert, S. R., et al. (2007). The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. The Journal of Clinical Investigation, 117, 1616-1626.
    • (2007) The Journal of Clinical Investigation , vol.117 , pp. 1616-1626
    • Wang, Y.1    Wan, C.2    Deng, L.3    Liu, X.4    Cao, X.5    Gilbert, S.R.6
  • 11
    • 84862803553 scopus 로고    scopus 로고
    • Mice with increased angiogenesis and osteogenesis due to conditional activation of HIF pathway in osteoblasts are protected from ovariectomy induced bone loss
    • Zhao, Q., Shen, X., Zhang, W., Zhu, G., Qi, J., & Deng, L. (2012). Mice with increased angiogenesis and osteogenesis due to conditional activation of HIF pathway in osteoblasts are protected from ovariectomy induced bone loss. Bone, 50, 763-770.
    • (2012) Bone , vol.50 , pp. 763-770
    • Zhao, Q.1    Shen, X.2    Zhang, W.3    Zhu, G.4    Qi, J.5    Deng, L.6
  • 13
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
    • Wang, G. L., & Semenza, G. L. (1993). Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction. Blood, 82, 3610-3615.
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 14
    • 0038380470 scopus 로고    scopus 로고
    • Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
    • Warnecke, C., Griethe, W., Weidemann, A., Jurgensen, J. S., Willam, C., Bachmann, S., et al. (2003). Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors. FASEB Journal, 17, 1186-1188.
    • (2003) FASEB Journal , vol.17 , pp. 1186-1188
    • Warnecke, C.1    Griethe, W.2    Weidemann, A.3    Jurgensen, J.S.4    Willam, C.5    Bachmann, S.6
  • 15
    • 19644393302 scopus 로고    scopus 로고
    • Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors
    • Chau, N. M., Rogers, P., Aherne, W., Carroll, V., Collins, I., McDonald, E., et al. (2005). Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors. Cancer Research, 65, 4918-4928.
    • (2005) Cancer Research , vol.65 , pp. 4918-4928
    • Chau, N.M.1    Rogers, P.2    Aherne, W.3    Carroll, V.4    Collins, I.5    McDonald, E.6
  • 16
    • 70349220913 scopus 로고    scopus 로고
    • Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
    • Shen, X., Wan, C., Ramaswamy, G., Mavalli, M., Wang, Y., Duvall, C. L., et al. (2009). Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice. Journal of Orthopaedic Research, 27, 1298-1305.
    • (2009) Journal of Orthopaedic Research , vol.27 , pp. 1298-1305
    • Shen, X.1    Wan, C.2    Ramaswamy, G.3    Mavalli, M.4    Wang, Y.5    Duvall, C.L.6
  • 17
    • 17944375553 scopus 로고    scopus 로고
    • PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
    • Castoria, G., Migliaccio, A., Bilancio, A., Di, D. M., de Falco, A., Lombardi, M., et al. (2001). PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO Journal, 20, 6050-6059.
    • (2001) EMBO Journal , vol.20 , pp. 6050-6059
    • Castoria, G.1    Migliaccio, A.2    Bilancio, A.3    Di, D.M.4    de Falco, A.5    Lombardi, M.6
  • 18
    • 2342418621 scopus 로고    scopus 로고
    • p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells
    • Cabodi, S., Moro, L., Baj, G., Smeriglio, M., Di, S. P., Gippone, S., et al. (2004). p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells. Journal of Cell Science, 117, 1603-1611.
    • (2004) Journal of Cell Science , vol.117 , pp. 1603-1611
    • Cabodi, S.1    Moro, L.2    Baj, G.3    Smeriglio, M.4    Di, S.P.5    Gippone, S.6
  • 20
    • 25144462239 scopus 로고    scopus 로고
    • Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts
    • Yen, M. L., Su, J. L., Chien, C. L., Tseng, K. W., Yang, C. Y., Chen, W. F., et al. (2005). Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts. Molecular Pharmacology, 68, 1061-1073.
    • (2005) Molecular Pharmacology , vol.68 , pp. 1061-1073
    • Yen, M.L.1    Su, J.L.2    Chien, C.L.3    Tseng, K.W.4    Yang, C.Y.5    Chen, W.F.6
  • 22
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. A., Malluche, H., Meunier, P. J., et al. (1987). Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. Journal of Bone and Mineral Research, 2, 595-610.
    • (1987) Journal of Bone and Mineral Research , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6
  • 24
    • 0036300146 scopus 로고    scopus 로고
    • Influence of experimental diabetes on the microcirculation of injured peripheral nerve: Functional and morphological aspects
    • Kennedy, J. M., & Zochodne, D. W. (2002). Influence of experimental diabetes on the microcirculation of injured peripheral nerve: Functional and morphological aspects. Diabetes, 51, 2233-2240.
    • (2002) Diabetes , vol.51 , pp. 2233-2240
    • Kennedy, J.M.1    Zochodne, D.W.2
  • 25
    • 0028362416 scopus 로고
    • Osteonal and hemi-osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone
    • Parfitt, A. M. (1994). Osteonal and hemi-osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone. Journal of Cellular Biochemistry, 1994(55), 273-286.
    • (1994) Journal of Cellular Biochemistry , vol.1994 , Issue.55 , pp. 273-286
    • Parfitt, A.M.1
  • 26
    • 0032402830 scopus 로고    scopus 로고
    • Osteoclast precursors as leukocytes: Importance of the area code
    • Parfitt, A. M. (1998). Osteoclast precursors as leukocytes: Importance of the area code. Bone, 1998(23), 491-494.
    • (1998) Bone , vol.1998 , Issue.23 , pp. 491-494
    • Parfitt, A.M.1
  • 27
    • 78650727785 scopus 로고    scopus 로고
    • Reduced local blood supply to the tibial metaphysis is associated with ovariectomy-induced osteoporosis in mice
    • Ding, W. G., Wei, Z. X., & Liu, J. B. (2011). Reduced local blood supply to the tibial metaphysis is associated with ovariectomy-induced osteoporosis in mice. Connective Tissue Research, 52, 25-29.
    • (2011) Connective Tissue Research , vol.52 , pp. 25-29
    • Ding, W.G.1    Wei, Z.X.2    Liu, J.B.3
  • 28
  • 29
    • 1542379706 scopus 로고    scopus 로고
    • The impact of gender on progression of renal disease: Potential role of estrogen-mediated vascular endothelial growth factor regulation and vascular protection
    • Kang, D. H., Yu, E. S., Yoon, K. I., & Johnson, R. (2004). The impact of gender on progression of renal disease: Potential role of estrogen-mediated vascular endothelial growth factor regulation and vascular protection. American Journal of Pathology, 164, 679-688.
    • (2004) American Journal of Pathology , vol.164 , pp. 679-688
    • Kang, D.H.1    Yu, E.S.2    Yoon, K.I.3    Johnson, R.4
  • 30
    • 0033756760 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in the human corpus luteum during the menstrual cycle and in early pregnancy
    • Sugino, N., Kashida, S., Takiguchi, S., Karube, A., & Kato, H. (2000). Expression of vascular endothelial growth factor and its receptors in the human corpus luteum during the menstrual cycle and in early pregnancy. Journal of Clinical Endocrinology and Metabolism, 85, 3919-3924.
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 3919-3924
    • Sugino, N.1    Kashida, S.2    Takiguchi, S.3    Karube, A.4    Kato, H.5
  • 31
    • 23644441755 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation analysis of gene expression in the rat uterus in vivo: Estrogen-induced recruitment of both estrogen receptor alpha and hypoxia-inducible factor 1 to the vascular endothelial growth factor promoter
    • Kazi, A. A., Jones, J. M., & Koos, R. D. (2005). Chromatin immunoprecipitation analysis of gene expression in the rat uterus in vivo: Estrogen-induced recruitment of both estrogen receptor alpha and hypoxia-inducible factor 1 to the vascular endothelial growth factor promoter. Molecular Endocrinology, 19, 2006-2019.
    • (2005) Molecular Endocrinology , vol.19 , pp. 2006-2019
    • Kazi, A.A.1    Jones, J.M.2    Koos, R.D.3
  • 32
    • 34249799626 scopus 로고    scopus 로고
    • Estrogen-induced activation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor expression, and edema in the uterus are mediated by the phosphatidylinositol 3-kinase/Akt pathway
    • Kazi, A. A., & Koos, R. D. (2007). Estrogen-induced activation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor expression, and edema in the uterus are mediated by the phosphatidylinositol 3-kinase/Akt pathway. Endocrinology, 2007, 2363-2374.
    • (2007) Endocrinology , vol.2007 , pp. 2363-2374
    • Kazi, A.A.1    Koos, R.D.2
  • 33
    • 33947113959 scopus 로고    scopus 로고
    • Influence of estradiol on vascular endothelial growth factor expression in bone: A study in Göttingen miniature pigs and human osteoblasts
    • Pufe, T., Claasen, H., Scholz-Ahrens, K. E., Varoga, D., Drescher, W., Franke, A. T., et al. (2007). Influence of estradiol on vascular endothelial growth factor expression in bone: A study in Göttingen miniature pigs and human osteoblasts. Calcified Tissue International, 2007, 184-191.
    • (2007) Calcified Tissue International , vol.2007 , pp. 184-191
    • Pufe, T.1    Claasen, H.2    Scholz-Ahrens, K.E.3    Varoga, D.4    Drescher, W.5    Franke, A.T.6
  • 34
    • 0036150402 scopus 로고    scopus 로고
    • Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen
    • Ivanova, T., Mendez, P., Garcia-Segura, L. M., & Beyer, C. (2002). Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen. Journal of Neuroendocrinology, 14, 73-79.
    • (2002) Journal of Neuroendocrinology , vol.14 , pp. 73-79
    • Ivanova, T.1    Mendez, P.2    Garcia-Segura, L.M.3    Beyer, C.4
  • 35
    • 0035881568 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K
    • Sun, M., Paciga, J. E., Feldman, R. I., Yuan, Z., Coppola, D., Lu, Y. Y., et al. (2001). Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K. Cancer Research, 61, 5985-5991.
    • (2001) Cancer Research , vol.61 , pp. 5985-5991
    • Sun, M.1    Paciga, J.E.2    Feldman, R.I.3    Yuan, Z.4    Coppola, D.5    Lu, Y.Y.6
  • 37
    • 4243175922 scopus 로고    scopus 로고
    • In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent
    • Guzelogli Kayisli, O., Kayisli, U. A., Luleci, G., & Arici, A. (2004). In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent. Biology of Reproduction, 2004(71), 714-721.
    • (2004) Biology of Reproduction , vol.2004 , Issue.71 , pp. 714-721
    • Guzelogli Kayisli, O.1    Kayisli, U.A.2    Luleci, G.3    Arici, A.4
  • 38
    • 0027406163 scopus 로고
    • High-dose estrogen inhibits bone resorption and stimulates bone formation in the ovariectomized mouse
    • Bain, S. D., Bailey, M. C., Celino, D. L., Lantry, M. M., & Edwards, M. W. (1993). High-dose estrogen inhibits bone resorption and stimulates bone formation in the ovariectomized mouse. Journal of Bone and Mineral Research, 8, 435-442.
    • (1993) Journal of Bone and Mineral Research , vol.8 , pp. 435-442
    • Bain, S.D.1    Bailey, M.C.2    Celino, D.L.3    Lantry, M.M.4    Edwards, M.W.5
  • 39
    • 74249106462 scopus 로고    scopus 로고
    • COMP-Ang1, a chimeric form of Angiopoietin 1, enhances BMP2-induced osteoblast differentiation and bone formation
    • Jeong, B. C., Kim, H. J., Bae, I. H., Lee, K. N., Lee, K. Y., Oh, W. M., et al. (2010). COMP-Ang1, a chimeric form of Angiopoietin 1, enhances BMP2-induced osteoblast differentiation and bone formation. Bone, 46, 479-486.
    • (2010) Bone , vol.46 , pp. 479-486
    • Jeong, B.C.1    Kim, H.J.2    Bae, I.H.3    Lee, K.N.4    Lee, K.Y.5    Oh, W.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.