Anomeric DNA quadruplexes: Modified thrombin aptamers

Artificial DNA: PNA and XNA

Volumn 5, Issue MAR, 2014, Pages

  Kolganova, Natalia A ^a   Varizhuk, Anna M ^a,b   Novikov, Roman A ^a,c   Florentiev, Vladimir L ^a   Pozmogova, Galina E ^b   Borisova, Olga F ^a   Shchyolkina, Anna K ^a   Smirnov, Igor P ^b   Kaluzhny, Dmitry N ^a   Timofeev, Edward N ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b FEDERAL RESEARCH AND CLINICAL CENTER OF PHYSICAL CHEMICAL MEDICINE OF FEDERAL MEDICAL BIOLOGICAL AGENCY   (Russian Federation)

^c N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Anomer; Anticoagulant properties; Nuclease resistance; Quadruplex; Thombin binding aptamer

Indexed keywords

APTAMER; GUANINE QUADRUPLEX; THROMBIN; THROMBIN BINDING APTAMER; UNCLASSIFIED DRUG; GUANINE; NUCLEASE; NUCLEOTIDE; OLIGOMER; ANTICOAGULANT AGENT; THROMBIN APTAMER;

ANTICOAGULATION; ARTICLE; BLOOD CLOTTING TIME; CONTROLLED STUDY; DNA CLEAVAGE; DNA MODIFICATION; DNA STRUCTURE; ENZYME MODIFICATION; HIGH TEMPERATURE; MELTING POINT; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE DEPENDENCE; THERMOSTABILITY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; PROTEIN CLEAVAGE; CHEMISTRY; CONFORMATION; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE; THERMODYNAMICS; THROMBIN TIME;

ANTICOAGULANTS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CIRCULAR DICHROISM; G-QUADRUPLEXES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; THERMODYNAMICS; THROMBIN TIME;

EID: 84899451974     PISSN: 1949095X     EISSN: 19490968     Source Type: Journal    
DOI: 10.4161/adna.28422     Document Type: Article

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