Secondary biliary cirrhosis in the rat is prevented by decreasing NF-κB nuclear translocation and TGF-β expression using allopurinol, an inhibitor of xanthine oxidase

Canadian Journal of Physiology and Pharmacology

Volumn 90, Issue 11, 2012, Pages 1469-1478

  Aldaba Muruato, Liseth R ^a   Moreno, Mario G ^a   Hernández Mercado, Elisa ^a   Shibayama, Mineko ^a   Muriel, Pablo ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Allopurinol; Bile duct ligation; Chronic liver damage; MMP 13; NF B; TGF ; Xanthine oxidase

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALLOPURINOL; COLLAGEN; COLLAGENASE 3; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIARY CIRRHOSIS; CHOLESTASIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ALLOPURINOL; ANIMALS; BIOLOGICAL MARKERS; CELL NUCLEUS; COLLAGEN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROSIS; LIVER; LIVER CIRRHOSIS, BILIARY; MALE; MATRIX METALLOPROTEINASE 13; NF-KAPPA B; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTEIN TRANSPORT; RATS; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA1; XANTHINE OXIDASE;

EID: 84870194260     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/y2012-125     Document Type: Article

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