-
1
-
-
80054052917
-
Lipoxygenase and leukotriene pathways: Biochemistry, biology, and roles in disease
-
Haeggstrom JZ, &, Funk CD, (2011) Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease. Chem Rev 111, 5866-5898.
-
(2011)
Chem Rev
, vol.111
, pp. 5866-5898
-
-
Haeggstrom, J.Z.1
Funk, C.D.2
-
2
-
-
77649172085
-
5-Lipoxygenase inhibitors: A review of recent developments and patents
-
Pergola C, &, Werz O, (2010) 5-Lipoxygenase inhibitors: a review of recent developments and patents. Expert Opin Ther Pat 20, 355-375.
-
(2010)
Expert Opin Ther Pat
, vol.20
, pp. 355-375
-
-
Pergola, C.1
Werz, O.2
-
3
-
-
66349101349
-
5-Lipoxygenase: Mechanisms of regulation
-
Radmark O, &, Samuelsson B, (2009) 5-Lipoxygenase: mechanisms of regulation. J Lipid Res 50 (Suppl), S40-S45.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Radmark, O.1
Samuelsson, B.2
-
4
-
-
34347397335
-
5-Lipoxygenase: Regulation of expression and enzyme activity
-
Radmark O, Werz O, Steinhilber D, &, Samuelsson B, (2007) 5-Lipoxygenase: regulation of expression and enzyme activity. Trends Biochem Sci 32, 332-341.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 332-341
-
-
Radmark, O.1
Werz, O.2
Steinhilber, D.3
Samuelsson, B.4
-
5
-
-
0034625136
-
5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases
-
Werz O, Klemm J, Samuelsson B, &, Radmark O, (2000) 5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases. Proc Natl Acad Sci USA 97, 5261-5266.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5261-5266
-
-
Werz, O.1
Klemm, J.2
Samuelsson, B.3
Radmark, O.4
-
6
-
-
0037177904
-
Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2)
-
Werz O, Szellas D, Steinhilber D, &, Radmark O, (2002) Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2). J Biol Chem 277, 14793-14800.
-
(2002)
J Biol Chem
, vol.277
, pp. 14793-14800
-
-
Werz, O.1
Szellas, D.2
Steinhilber, D.3
Radmark, O.4
-
7
-
-
0036719157
-
Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes
-
Werz O, Burkert E, Fischer L, Szellas D, Dishart D, Samuelsson B, Radmark O, &, Steinhilber D, (2002) Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes. FASEB J 16, 1441-1443.
-
(2002)
FASEB J
, vol.16
, pp. 1441-1443
-
-
Werz, O.1
Burkert, E.2
Fischer, L.3
Szellas, D.4
Dishart, D.5
Samuelsson, B.6
Radmark, O.7
Steinhilber, D.8
-
8
-
-
4744375385
-
Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523
-
Luo M, Jones SM, Phare SM, Coffey MJ, Peters-Golden M, &, Brock TG, (2004) Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523. J Biol Chem 279, 41512-41520.
-
(2004)
J Biol Chem
, vol.279
, pp. 41512-41520
-
-
Luo, M.1
Jones, S.M.2
Phare, S.M.3
Coffey, M.J.4
Peters-Golden, M.5
Brock, T.G.6
-
9
-
-
84895763429
-
Sulfo-NHS-SS-biotin derivatization: A versatile tool for MALDI mass analysis of PTMs in lysine-rich proteins
-
doi: 10.1002/pmic.201300309
-
Markoutsa S, Bahr U, Papasotiriou DG, Häfner AK, Karas M, &, Sorg BL, (2014) Sulfo-NHS-SS-biotin derivatization: a versatile tool for MALDI mass analysis of PTMs in lysine-rich proteins. Proteomics. doi: 10.1002/pmic.201300309.
-
(2014)
Proteomics
-
-
Markoutsa, S.1
Bahr, U.2
Papasotiriou, D.G.3
Häfner, A.K.4
Karas, M.5
Sorg, B.L.6
-
10
-
-
77952312969
-
Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis
-
Radmark O, &, Samuelsson B, (2010) Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. Biochem Biophys Res Commun 396, 105-110.
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 105-110
-
-
Radmark, O.1
Samuelsson, B.2
-
11
-
-
21344469741
-
Development of 5-lipoxygenase inhibitors - Lessons from cellular enzyme regulation
-
Werz O, &, Steinhilber D, (2005) Development of 5-lipoxygenase inhibitors-lessons from cellular enzyme regulation. Biochem Pharmacol 70, 327-333.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 327-333
-
-
Werz, O.1
Steinhilber, D.2
-
12
-
-
0027476155
-
Regulation of eicosanoid biosynthesis in the macrophage. Involvement of protein tyrosine phosphorylation and modulation by selective protein tyrosine kinase inhibitors
-
Glaser KB, Sung A, Bauer J, &, Weichman BM, (1993) Regulation of eicosanoid biosynthesis in the macrophage. Involvement of protein tyrosine phosphorylation and modulation by selective protein tyrosine kinase inhibitors. Biochem Pharmacol 45, 711-721.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 711-721
-
-
Glaser, K.B.1
Sung, A.2
Bauer, J.3
Weichman, B.M.4
-
13
-
-
0029915250
-
Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase
-
Lepley RA, Muskardin DT, &, Fitzpatrick FA, (1996) Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase. J Biol Chem 271, 6179-6184.
-
(1996)
J Biol Chem
, vol.271
, pp. 6179-6184
-
-
Lepley, R.A.1
Muskardin, D.T.2
Fitzpatrick, F.A.3
-
14
-
-
0028218772
-
Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line
-
Hagmann W, (1994) Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line. Biochem J 299 (Pt 2), 467-472.
-
(1994)
Biochem J
, vol.299
, Issue.PART 2
, pp. 467-472
-
-
Hagmann, W.1
-
16
-
-
0028608865
-
On the induction of 5-lipoxygenase expression and activity in HL-60 cells: Effects of vitamin D3, retinoic acid, DMSO and TGF beta
-
Brungs M, Radmark O, Samuelsson B, &, Steinhilber D, (1994) On the induction of 5-lipoxygenase expression and activity in HL-60 cells: effects of vitamin D3, retinoic acid, DMSO and TGF beta. Biochem Biophys Res Commun 205, 1572-1580.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1572-1580
-
-
Brungs, M.1
Radmark, O.2
Samuelsson, B.3
Steinhilber, D.4
-
17
-
-
0025963608
-
Expression of src family genes during monocytic differentiation of HL-60 cells
-
Katagiri K, Katagiri T, Koyama Y, Morikawa M, Yamamoto T, &, Yoshida T, (1991) Expression of src family genes during monocytic differentiation of HL-60 cells. J Immunol 146, 701-707.
-
(1991)
J Immunol
, vol.146
, pp. 701-707
-
-
Katagiri, K.1
Katagiri, T.2
Koyama, Y.3
Morikawa, M.4
Yamamoto, T.5
Yoshida, T.6
-
18
-
-
0023352242
-
Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells
-
Quintrell N, Lebo R, Varmus H, Bishop JM, Pettenati MJ, Le Beau MM, Diaz MO, &, Rowley JD, (1987) Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells. Mol Cell Biol 7, 2267-2275.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 2267-2275
-
-
Quintrell, N.1
Lebo, R.2
Varmus, H.3
Bishop, J.M.4
Pettenati, M.J.5
Le Beau, M.M.6
Diaz, M.O.7
Rowley, J.D.8
-
19
-
-
33748756035
-
Verotoxin-1 stimulation of macrophage-like THP-1 cells up-regulates tissue factor expression through activation of c-Yes tyrosine kinase: Possible signal transduction in tissue factor up-regulation
-
Murata K, Higuchi T, Takada K, Oida K, Horie S, &, Ishii H, (2006) Verotoxin-1 stimulation of macrophage-like THP-1 cells up-regulates tissue factor expression through activation of c-Yes tyrosine kinase: possible signal transduction in tissue factor up-regulation. Biochim Biophys Acta 1762, 835-843.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 835-843
-
-
Murata, K.1
Higuchi, T.2
Takada, K.3
Oida, K.4
Horie, S.5
Ishii, H.6
-
20
-
-
33947198166
-
The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine
-
Fumagalli L, Zhang H, Baruzzi A, Lowell CA, &, Berton G, (2007) The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine. J Immunol 178, 3874-3885.
-
(2007)
J Immunol
, vol.178
, pp. 3874-3885
-
-
Fumagalli, L.1
Zhang, H.2
Baruzzi, A.3
Lowell, C.A.4
Berton, G.5
-
21
-
-
0033555864
-
Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck
-
Mocsai A, Ligeti E, Lowell CA, &, Berton G, (1999) Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck. J Immunol 162, 1120-1126.
-
(1999)
J Immunol
, vol.162
, pp. 1120-1126
-
-
Mocsai, A.1
Ligeti, E.2
Lowell, C.A.3
Berton, G.4
-
22
-
-
0342313568
-
Kinase pathways in chemoattractant-induced degranulation of neutrophils: The role of p38 mitogen-activated protein kinase activated by Src family kinases
-
Mocsai A, Jakus Z, Vantus T, Berton G, Lowell CA, &, Ligeti E, (2000) Kinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinases. J Immunol 164, 4321-4331.
-
(2000)
J Immunol
, vol.164
, pp. 4321-4331
-
-
Mocsai, A.1
Jakus, Z.2
Vantus, T.3
Berton, G.4
Lowell, C.A.5
Ligeti, E.6
-
23
-
-
0025735567
-
Alterations in tyrosine protein kinase activities upon activation of human neutrophils
-
Berkow RL, &, Dodson RW, (1991) Alterations in tyrosine protein kinase activities upon activation of human neutrophils. J Leukoc Biol 49, 599-604.
-
(1991)
J Leukoc Biol
, vol.49
, pp. 599-604
-
-
Berkow, R.L.1
Dodson, R.W.2
-
24
-
-
0028364801
-
Lipopolysaccharide-induced cytokine production in human monocytes: Role of tyrosine phosphorylation in transmembrane signal transduction
-
Beaty CD, Franklin TL, Uehara Y, &, Wilson CB, (1994) Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction. Eur J Immunol 24, 1278-1284.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1278-1284
-
-
Beaty, C.D.1
Franklin, T.L.2
Uehara, Y.3
Wilson, C.B.4
-
25
-
-
0028087327
-
Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6
-
Ziegler-Heitbrock HW, Schraut W, Wendelgass P, Strobel M, Sternsdorf T, Weber C, Aepfelbacher M, Ehlers M, Schutt C, &, Haas JG, (1994) Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6. J Leukoc Biol 55, 73-80.
-
(1994)
J Leukoc Biol
, vol.55
, pp. 73-80
-
-
Ziegler-Heitbrock, H.W.1
Schraut, W.2
Wendelgass, P.3
Strobel, M.4
Sternsdorf, T.5
Weber, C.6
Aepfelbacher, M.7
Ehlers, M.8
Schutt, C.9
Haas, J.G.10
-
26
-
-
24944572154
-
Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells
-
Werz O, Tretiakova I, Michel A, Ulke-Lemee A, Hornig M, Franke L, Schneider G, Samuelsson B, Radmark O, &, Steinhilber D, (2005) Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells. Proc Natl Acad Sci USA 102, 13164-13169.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13164-13169
-
-
Werz, O.1
Tretiakova, I.2
Michel, A.3
Ulke-Lemee, A.4
Hornig, M.5
Franke, L.6
Schneider, G.7
Samuelsson, B.8
Radmark, O.9
Steinhilber, D.10
-
27
-
-
0033954256
-
The protein data bank
-
Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, &, Bourne PE, (2000) The protein data bank. Nucleic Acids Res 28, 235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
28
-
-
0028961439
-
Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3
-
Brungs M, Radmark O, Samuelsson B, &, Steinhilber D, (1995) Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci USA 92, 107-111.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 107-111
-
-
Brungs, M.1
Radmark, O.2
Samuelsson, B.3
Steinhilber, D.4
-
29
-
-
33746605173
-
Src protein tyrosine kinase family and acute inflammatory responses
-
Okutani D, Lodyga M, Han B, &, Liu M, (2006) Src protein tyrosine kinase family and acute inflammatory responses. Am J Physiol Lung Cell Mol Physiol 291, L129-L141.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Okutani, D.1
Lodyga, M.2
Han, B.3
Liu, M.4
-
30
-
-
0031439247
-
Cellular functions regulated by Src family kinases
-
Thomas SM, &, Brugge JS, (1997) Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 13, 513-609.
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
Brugge, J.S.2
-
31
-
-
0035844240
-
5-Lipoxygenase interacts with coactosin-like protein
-
Provost P, Doucet J, Hammarberg T, Gerisch G, Samuelsson B, &, Radmark O, (2001) 5-Lipoxygenase interacts with coactosin-like protein. J Biol Chem 276, 16520-16527.
-
(2001)
J Biol Chem
, vol.276
, pp. 16520-16527
-
-
Provost, P.1
Doucet, J.2
Hammarberg, T.3
Gerisch, G.4
Samuelsson, B.5
Radmark, O.6
-
32
-
-
58649091333
-
Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export
-
Flamand N, Luo M, Peters-Golden M, &, Brock TG, (2009) Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export. J Biol Chem 284, 306-313.
-
(2009)
J Biol Chem
, vol.284
, pp. 306-313
-
-
Flamand, N.1
Luo, M.2
Peters-Golden, M.3
Brock, T.G.4
-
33
-
-
84856152048
-
Influence of amino acid composition and phosphorylation on the ion yields of peptides in MALDI-MS
-
Asakawa D, Moriguchi S, &, Takayama M, (2012) Influence of amino acid composition and phosphorylation on the ion yields of peptides in MALDI-MS. J Am Soc Mass Spectrom 23, 108-115.
-
(2012)
J Am Soc Mass Spectrom
, vol.23
, pp. 108-115
-
-
Asakawa, D.1
Moriguchi, S.2
Takayama, M.3
-
34
-
-
0038661167
-
Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors
-
Fischer L, Szellas D, Radmark O, Steinhilber D, &, Werz O, (2003) Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors. FASEB J 17, 949-951.
-
(2003)
FASEB J
, vol.17
, pp. 949-951
-
-
Fischer, L.1
Szellas, D.2
Radmark, O.3
Steinhilber, D.4
Werz, O.5
-
35
-
-
66349108979
-
Gas-phase intramolecular phosphate shift in phosphotyrosine-containing peptide monoanions
-
Edelson-Averbukh M, Shevchenko A, Pipkorn R, &, Lehmann WD, (2009) Gas-phase intramolecular phosphate shift in phosphotyrosine-containing peptide monoanions. Anal Chem 81, 4369-4381.
-
(2009)
Anal Chem
, vol.81
, pp. 4369-4381
-
-
Edelson-Averbukh, M.1
Shevchenko, A.2
Pipkorn, R.3
Lehmann, W.D.4
-
36
-
-
84857499171
-
Mass spectrometric characterization of phosphorylated peptides using MALDI in-source decay via redox reactions
-
Asakawa D, &, Takayama M, (2012) Mass spectrometric characterization of phosphorylated peptides using MALDI in-source decay via redox reactions. J Mass Spectrom 47, 180-187.
-
(2012)
J Mass Spectrom
, vol.47
, pp. 180-187
-
-
Asakawa, D.1
Takayama, M.2
-
37
-
-
0024269038
-
Augmented expression of a myeloid-specific protein tyrosine kinase gene (hck) after macrophage activation
-
Ziegler SF, Wilson CB, &, Perlmutter RM, (1988) Augmented expression of a myeloid-specific protein tyrosine kinase gene (hck) after macrophage activation. J Exp Med 168, 1801-1810.
-
(1988)
J Exp Med
, vol.168
, pp. 1801-1810
-
-
Ziegler, S.F.1
Wilson, C.B.2
Perlmutter, R.M.3
-
38
-
-
0026530288
-
Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages
-
Boulet I, Ralph S, Stanley E, Lock P, Dunn AR, Green SP, &, Phillips WA, (1992) Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages. Oncogene 7, 703-710.
-
(1992)
Oncogene
, vol.7
, pp. 703-710
-
-
Boulet, I.1
Ralph, S.2
Stanley, E.3
Lock, P.4
Dunn, A.R.5
Green, S.P.6
Phillips, W.A.7
-
39
-
-
0028170407
-
5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins
-
Lepley RA, &, Fitzpatrick FA, (1994) 5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins. J Biol Chem 269, 24163-24168.
-
(1994)
J Biol Chem
, vol.269
, pp. 24163-24168
-
-
Lepley, R.A.1
Fitzpatrick, F.A.2
-
40
-
-
28844492469
-
Phosphorylation by protein kinase A inhibits nuclear import of 5-lipoxygenase
-
Luo M, Jones SM, Flamand N, Aronoff DM, Peters-Golden M, &, Brock TG, (2005) Phosphorylation by protein kinase A inhibits nuclear import of 5-lipoxygenase. J Biol Chem 280, 40609-40616.
-
(2005)
J Biol Chem
, vol.280
, pp. 40609-40616
-
-
Luo, M.1
Jones, S.M.2
Flamand, N.3
Aronoff, D.M.4
Peters-Golden, M.5
Brock, T.G.6
-
41
-
-
78651453239
-
The structure of human 5-lipoxygenase
-
Gilbert NC, Bartlett SG, Waight MT, Neau DB, Boeglin WE, Brash AR, &, Newcomer ME, (2011) The structure of human 5-lipoxygenase. Science 331, 217-219.
-
(2011)
Science
, vol.331
, pp. 217-219
-
-
Gilbert, N.C.1
Bartlett, S.G.2
Waight, M.T.3
Neau, D.B.4
Boeglin, W.E.5
Brash, A.R.6
Newcomer, M.E.7
-
42
-
-
80755171216
-
Dimerization of human 5-lipoxygenase
-
Hafner AK, Cernescu M, Hofmann B, Ermisch M, Hornig M, Metzner J, Schneider G, Brutschy B, &, Steinhilber D, (2011) Dimerization of human 5-lipoxygenase. Biol Chem 392, 1097-1111.
-
(2011)
Biol Chem
, vol.392
, pp. 1097-1111
-
-
Hafner, A.K.1
Cernescu, M.2
Hofmann, B.3
Ermisch, M.4
Hornig, M.5
Metzner, J.6
Schneider, G.7
Brutschy, B.8
Steinhilber, D.9
-
43
-
-
79960624451
-
Reaction rate of propene pyrolysis
-
Han P, Su K, Liu Y, Wang Y, Wang X, Zeng Q, Cheng L, &, Zhang L, (2011) Reaction rate of propene pyrolysis. J Comput Chem 32, 2745-2755.
-
(2011)
J Comput Chem
, vol.32
, pp. 2745-2755
-
-
Han, P.1
Su, K.2
Liu, Y.3
Wang, Y.4
Wang, X.5
Zeng, Q.6
Cheng, L.7
Zhang, L.8
|