Impact of targeted specific antibiotic delivery for gut microbiota modulation on high-fructose-fed rats

Applied Biochemistry and Biotechnology

Volumn 172, Issue 8, 2014, Pages 3810-3826

  Jena, Prasant Kumar ^a   Singh, Shilpa ^a   Prajapati, Bhumika ^a   Nareshkumar, G ^b   Mehta, Tejal ^c   Seshadri, Sriram ^a  

^a NIRMA UNIVERSITY   (India)

^b M S UNIVERSITY OF BARODA   (India)

^c NIRMA UNIVERSITY   (India)

Author keywords

Cefdinir; Diabetes; Fructose; Gut microbiota; Inflammation; Microspheres

Indexed keywords

ANTIBIOTICS; GLUCOSE; MEDICAL PROBLEMS; MICROSPHERES; RATS;

CEFDINIR; EXPERIMENTAL EVIDENCE; GUT MICROBIOTA; HISTOLOGICAL CHANGES; HISTOLOGICAL EVALUATION; INFLAMMATION; ORAL ADMINISTRATION; THERAPEUTIC APPLICATION;

FRUCTOSE;

ANTIINFECTIVE AGENT; CARBOHYDRATE DIET; CEFDINIR; CEPHALOSPORIN DERIVATIVE; FRUCTOSE; MICROSPHERE;

ANIMAL; BLOOD ANALYSIS; BODY WEIGHT; CARBOHYDRATE DIET; CYTOLOGY; DRINKING; DRUG EFFECTS; DRUG RELEASE; FECES; GLUCOSE TOLERANCE TEST; INTESTINE; LIVER; MALE; METABOLISM; MICROBIOLOGY; MICROFLORA; RAT; WISTAR RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOOD CHEMICAL ANALYSIS; BODY WEIGHT; CEPHALOSPORINS; DIETARY CARBOHYDRATES; DRINKING; DRUG LIBERATION; FECES; FRUCTOSE; GLUCOSE TOLERANCE TEST; INTESTINES; LIVER; MALE; MICROBIOTA; MICROSPHERES; RATS; RATS, WISTAR;

EID: 84899419678     PISSN: 02732289     EISSN: 15590291     Source Type: Journal    
DOI: 10.1007/s12010-014-0772-y     Document Type: Article

References (33)

1. International Diabetes Federation. (2012). Diabetes atlas (5th ed.). Brussels: International Diabetes Federation.
2. Bayturan, O., Tuzcu, E. M., Lavoie, A., et al. (2010). The metabolic syndrome, its component risk factors, and progression of coronary atherosclerosis. Archives of Internal Medicine, 170(5), 478-484.
3. Basciano, H., Federico, L., & Adeli, K. (2005). Fructose, insulin resistance, and metabolic dyslipidemia. Nutrition and Metabolism, 2(5), 1-14. doi:10.1186/1743-7075-2-5.
4. Evans, J. L., Maddux, B. A., & Goldfine, I. D. (2005). The molecular basis for oxidative stress-induced insulin resistance. Antioxidant Redox Signal, 7(7-8), 1040-1052. (Pubitemid 40967154)
5. Tuomilehto, J., Lindström, J., Eriksson, J. G., et al. (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New England Journal of Medicine, 344, 1343-1350. (Pubitemid 32378388)
6. Willett, W., Manson, J., & Liu, S. (2001). Glycemic index, glycemic load, and risk of type 2 diabetes. American Journal of Clinical Nutrition, 76, 274S-280S.
7. Turnbaugh, P. J., Hamady, M., Yatsunenko, T., et al. (2009). A core gut microbiome in obese and lean twins. Nature, 457(7228), 480-484.
8. Hildebrandt, M. A., Hoffmann, C., Sherrill-Mix, S. A., et al. (2009). High-fat diet determines the composition of the murine gut microbiome independently of obesity. Gastroenterology, 137(5), 1716-1724. e1711-1712.
9. Dethlefsen, L., Huse, S., Sogin, M. L., & Relman, D. A. (2008). The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biology, 6(11), e280.
10. Frank, D. N., St Amand, A. L., Feldman, R. A., et al. (2007). Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proceeding of National Academy of Science (PNAS), 104(34), 13780-13785. (Pubitemid 350003397)
11. Duncan, S. H., Lobley, G. E., Holtrop, G., et al. (2008). Human colonic microbiota associated with diet, obesity and weight loss. International Journal of Obesity, 32(11), 1720-1724.
12. Turnbaugh, P. J., Baeckhed, F., Fulton, L., & Gordon, J. I. (2008). Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host & Microbe, 3, 213-223. (Pubitemid 351494716)
13. Murphy, E. F., Cotter, P. D., Healy, S., et al. (2010). Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models. Gut, 9, 1635-1642.
14. Jernberg, C., Lofmark, S., Edlund, C., & Jansson, J. K. (2010). Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology, 156, 3216-3223.
15. Shen, X., Yua, D., Zhua, L., et al. (2011). Electrospun diclofenac sodium loaded Eudragit L100-55 nanofibers for colon-targeted drug delivery. International Journal of Pharmaceutics, 408, 200-207.
16. Gupta, V. K., Assmus, M. W., Beckert, T. E., & Price, J. C. (2001). A novel pH- and time-based multi-unit potential colonic drug delivery system. II. Optimization of multiple response variables. International Journal of Pharmaceutics, 213(1-2), 93-102. (Pubitemid 32119465)
17. Maghsoodi, M., & Esfahani, M. (2009). Preparation of microparticles of naproxen with Eudragit RS and talc by spherical crystallization technique. Pharmaceutical Development Technology, 14(4), 442-450.
18. Jain, D., Panda, A. K., & Majumdar, D. K. (2005). Eudragit S100 entrapped insulin microspheres for oral delivery. AAPS Pharmaceutical Science & Technology, 6(1), 100-107.
19. Perry, C. M., & Scott, L. J. (2004). Cefdinir: a review of its use in the management of mild-to-moderate bacterial infections. Drugs, 64(13), 1433-1464. (Pubitemid 38980457)
20. Basu, S. K., & Adhiyaman, R. (2008). Preparation and characterization of Nitrendipine-loaded Eudragit RL 100 microspheres prepared by an emulsion-solvent evaporation method. Tropical Journal of Pharmaceutical Research, 7(3), 1033-1041.
21. Aleem, O., Kuchekar, B., Pore, Y., & Late, S. (2008). Effect of β-cyclodextrin and hydroxypropyl β-cyclodextrin complexation on physicochemical properties and antimicrobial activity of cefdinir. Journal of Pharmaceutical and Biomedical Analysis, 47, 535-540.
22. Yadav, H., Jain, S., & Sinha, P. R. (2007). Antidiabetic effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats. Nutrition, 23(1), 62-68. (Pubitemid 44959762)
23. Xie, N., Cui, Y., Yin, Y. N., et al. (2011). Effects of two Lactobacillus strains on lipid metabolism and intestinal microflora in rats fed a high-cholesterol diet. BMC Complementary and Alternative Medicine, 11, 53.
24. Park, J., Park, H. J., Cho, W., Cha, K. H., Kang, Y. S., & Hwang, S. J. (2010). Preparation and pharmaceutical characterization of amorphous cefdinir using spray-drying and SAS-process. International Journal of Pharmaceutics, 396, 239-245.
25. Shanahan, F., & Murphy, E. (2011). The hybrid science of diet, microbes, and metabolic health. American Journal of Clinical Nutrition, 94(1), 1-2.
26. Carvalho, B.M., Guadagnini, D., Tsukumo, D.M., et al. (2012). Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice. Diabetologia, 55, 2823-2834.
27. Membrez, M., Blancher, F., Jaquet, M., et al. (2008). Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. FASEB Journal, 22(7), 2416-2426. (Pubitemid 351948659)
28. Everson, S. A., Goldberg, D. E., Helmrich, S. P., Lakkam, T. A., et al. (1998). Weight gain and the risk of developing insulin resistance syndrome. Diabetes Care, 21, 1637-1643.
29. Group DS. (1999). Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. Lancet, 354, 617-621.
30. Polavarapu, R., Spitz, D. R., Sim, J. E., Follansbee, M. H., et al. (1998). Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil. Hepatology, 27, 1317-1323. (Pubitemid 28227859)
31. Felig, P., Wahren, J., & Hendler, R. (1978). Influence of maturity-onset splanchnic glucose uptake in non-insulin-dependent diabetes mellitus diabetes on splanchnic glucose balance after oral glucose ingestion. Diabetes, 27, 121-126. (Pubitemid 8294837)
32. Singh, V., & Chaudhary, A. K. (2011). Preparation of Eudragit E100 microspheres by modified solvent evaporation method. Acta Poloniae Pharmaceutica-Drug Research, 68(6), 975-980.
33. Trapani, A., Laquintana, V., Denora, N., Lopedota, A., Cutrignelli, A., & Franco, M. (2007). Eudragit RS 100 microparticles containing 2-hydroxypropyl-β-cyclodextrin and glutathione: physicochemical characterization, drug release and transport studies. European Journal of Pharmaceutical Sciences, 30, 64-74. (Pubitemid 44908928)