Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age

Epigenetics

Volumn 9, Issue 4, 2014, Pages 492-502

  Kaz, Andrew M ^a,b,c   Wong, Chao Jen ^a   Dzieciatkowski, Slavomir ^a   Luo, Yanxin ^a,d   Schoen, Robert E ^e   Grady, William M ^a,c  

^a Fred Hutchinson Cancer Research Center   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d SUN YAT SEN UNIVERSITY   (China)

^e UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Colorectal cancer; DNA methylation; Field effect; Methylation microarray; Normal colon methylation

Indexed keywords

CPG DINUCLEOTIDE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DINUCLEOTIDE; ESTROGEN RECEPTOR ALPHA; EVL PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; ESTROGEN RECEPTOR ALPHA, HUMAN; EVL PROTEIN, HUMAN;

ADULT; AGE; ANALYSIS; ANATOMICAL VARIATION; ARTICLE; CLINICAL ARTICLE; COLON; COLON BIOPSY; COMPARATIVE STUDY; DNA METHYLATION; DNA STRUCTURE; FEMALE; GENE SET ENRICHMENT ANALYSIS; HUMAN; HUMAN TISSUE; LONG INTERSPERSED REPEAT; MALE; PYROSEQUENCING; SAT ALPHA; SEX DIFFERENCE; AGED; ANATOMY AND HISTOLOGY; CPG ISLAND; GENETICS; HUMAN GENOME; METABOLISM; MIDDLE AGED; PROMOTER REGION; RECTUM; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; CELL ADHESION MOLECULES; COLON; CPG ISLANDS; DNA METHYLATION; ESTROGEN RECEPTOR ALPHA; FEMALE; GENOME, HUMAN; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RECTUM; SEX FACTORS;

EID: 84899155297     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.27650     Document Type: Article

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