DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids

Digestive Diseases and Sciences

Volumn 56, Issue 2, 2011, Pages 387-396

  Worthley, Daniel L ^a,b   Whitehall, Vicki L J ^a,b   Le Leu, Richard K ^c   Irahara, Natsumi ^d   Buttenshaw, Ronald L ^a,b   Mallitt, Kylie Ann ^b   Greco, Sonia A ^a,b   Ramsnes, Ingunn ^a,b   Winter, Jean ^c   Hu, Ying ^c   Ogino, Shuji ^d,e   Young, Graeme P ^c   Leggett, Barbara A ^a,b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c FLINDERS UNIVERSITY   (Australia)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Carcinogenesis; Colorectal cancer; DNA methylation; Epigenetics

Indexed keywords

AMMONIA; SHORT CHAIN FATTY ACID;

ADULT; AGED; ARTICLE; CACNA1G GENE; CDKN2A GENE; CELL PROLIFERATION; CONTROLLED STUDY; CPG ISLAND; CRYPT CELL; DNA METHYLATION; DNA SEQUENCE; ESR1 GENE; FECES LEVEL; FEMALE; GATA5 GENE; HIC1 GENE; HUMAN; HUMAN TISSUE; IGF2 GENE; MALE; MARKER GENE; MGMT GENE; MINT1 GENE; MINT2 GENE; MINT31 GENE; MLH1 GENE; NEUROG1 GENE; PH; PRIORITY JOURNAL; RECTUM BIOPSY; RECTUM MUCOSA; RUNX3 GENE; SFRP1 GENE; SOCS1 GENE; TUMOR GENE;

ABERRANT CRYPT FOCI; ADULT; AGED; AMMONIA; BIOLOGICAL MARKERS; COLORECTAL NEOPLASMS; DNA METHYLATION; FATTY ACIDS, VOLATILE; FECES; FEMALE; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; RECTUM;

EID: 79952446883     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1312-4     Document Type: Article

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