Widespread differences in cortex DNA methylation of the "language gene" CNTNAP2 between humans and chimpanzees

Epigenetics

Volumn 9, Issue 4, 2014, Pages 533-545

  Schneider, Eberhard ^a   El Hajj, Nady ^a   Richter, Steven ^a   Roche Santiago, Justin ^a   Nanda, Indrajit ^a   Schempp, Werner ^b   Riederer, Peter ^c   Navarro, Bianca ^d   Bontrop, Ronald E ^e   Kondova, Ivanela ^e   Scholz, Claus Jürgen ^a   Haaf, Thomas ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^e BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

Author keywords

CNTNAP2; DNA methylation; Human brain evolution; Human chimpanzee comparison; Human specific communication; Language

Indexed keywords

ADULT; AGED; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTACTIN ASSOCIATED PROTEIN LIKE 2 GENE; CPG ISLAND; DNA METHYLATION; DNA MICROARRAY; FEMALE; FRONTAL CORTEX; GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; LANGUAGE ABILITY; MALE; MIDDLE AGED; NONHUMAN; PROTEIN EXPRESSION; PYROSEQUENCING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERIAL ANALYSIS OF GENE EXPRESSION; VERY ELDERLY; YOUNG ADULT; ANIMAL; BRAIN CORTEX; CHILD; COMPARATIVE STUDY; GENETICS; LANGUAGE; METABOLISM; PAN TROGLODYTES; PHYSIOLOGY; PROTEIN PROCESSING; SPECIES DIFFERENCE;

CNTNAP2 PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CEREBRAL CORTEX; CHILD; DNA METHYLATION; FEMALE; HUMANS; LANGUAGE; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; PAN TROGLODYTES; PROTEIN SPLICING; SPECIES SPECIFICITY; YOUNG ADULT;

EID: 84899153582     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.27689     Document Type: Article

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