Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients

Cancer Letters

Volumn 163, Issue 1, 2001, Pages 109-116

  Okada, Eikichi ^a   Murai, Yoshihiro ^a   Matsui, Kazuhiro ^a   Isizawa, Shin ^a   Cheng, Chunmei ^a   Masuda, Mitsunobu ^b   Takano, Yasuo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b YOKOHAMA CITY UNIVERSITY MEDICAL CENTER   (Japan)

Author keywords

Gastric cancer; Survivin; Tumor cell nuclei

Indexed keywords

ANTI SURVIVIN ANTIBODY; POLYCLONAL ANTIBODY; SURVIVIN; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; ANALYTIC METHOD; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CANCER SURVIVAL; CELL FRACTIONATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; STOMACH CARCINOMA;

ADULT; AGED; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL FRACTIONATION; CELL NUCLEUS; DNA, COMPLEMENTARY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM PROTEINS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; SURVIVAL RATE;

EID: 0035835484     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00677-7     Document Type: Article

References (25)

1. Cell death in development
2. Caspases: Intracellular signaling by proteolysis
3. A novelanti-apoptosis gene, survivin, expressed in cancer and lymphoma
4. The cancer anti-apoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell-dependent expression
5. The inhibitors of apoptosis (IAPs) and their emerging role in cancer
6. IAP family proteins-suppressors of apoptosis
7. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer
8. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas
9. Antiapoptosis molecule survivin and recurrence of bladder cancer
10. Anti-apoptosis gene, survivin, and prognosis of neuroblastoma
11. Pathological studies of human gastric cancers
12. Comparison of seven cell lines derived from human gastric carcinomas
13. Expression of a hybrid form of alkaline phosphatase isoenzyme in a newly established cell line (HuG-1) from a gastric cancer patient
14. High expression of survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma
15. High levels of expression and nuclear localization of interleukin-1 b converting enzyme (ICE) and CPP32 in favorable human neuroblastomas
16. Survivin apoptosis: An interloper between cell death and cell proliferation in cancer
17. Treatment results of gastric cancer patients: Japanese experience
18. Cyclin D2, but not cyclin D1 over-expression closely correlates with gastric cancer progression and prognosis
19. Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases
20. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma
21. Apoptosis and proliferative activity of non-Hodgkin's lymphomas: Comparison with expression of bcl-2, p53 and c-myc proteins
22. Apoptosis, proliferative activity and bcl-2 expression in Epstein-Barr-virus-positive non-hodgkin's lymphomas
23. Comparison between the monoclonal antibodies Ki-67 and PC10 in 125 malignant lymphomas
24. Apoptosis in gastric carcinomas and its association with proliferation and differentiation
25. Apoptosis: Its significance in cancer and cancer therapy