메뉴 건너뛰기




Volumn 268, Issue , 2014, Pages 117-126

Central injection of relaxin-3 receptor (RXFP3) antagonist peptides reduces motivated food seeking and consumption in C57BL/6J mice

Author keywords

Arousal; Feeding; Motivation; Neuropeptide; Relaxin 3; RXFP3

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PLACEBO; RELAXIN 3; RELAXIN 3 RECEPTOR; RELAXIN 3 RECEPTOR ANTAGONIST PEPTIDE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; CENTRAL NERVOUS SYSTEM AGENTS; PEPTIDE; SALPR PROTEIN, MOUSE;

EID: 84899147561     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.03.037     Document Type: Article
Times cited : (36)

References (88)
  • 1
    • 27144454353 scopus 로고    scopus 로고
    • From waking to sleeping: neuronal and chemical substrates
    • Jones B.E. From waking to sleeping: neuronal and chemical substrates. Trends Pharmacol Sci 2005, 26:578-586.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 578-586
    • Jones, B.E.1
  • 2
    • 27644457084 scopus 로고    scopus 로고
    • Hypothalamic regulation of sleep and circadian rhythms
    • Saper C.B., Scammell T.E., Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005, 437:1257-1263.
    • (2005) Nature , vol.437 , pp. 1257-1263
    • Saper, C.B.1    Scammell, T.E.2    Lu, J.3
  • 3
    • 84859373495 scopus 로고    scopus 로고
    • Circadian and wakefulness-sleep modulation of cognition in humans
    • Wright K.P., Lowry C.A., Lebourgeois M.K. Circadian and wakefulness-sleep modulation of cognition in humans. Front Mol Neurosci 2012, 5:50.
    • (2012) Front Mol Neurosci , vol.5 , pp. 50
    • Wright, K.P.1    Lowry, C.A.2    Lebourgeois, M.K.3
  • 4
    • 84867130069 scopus 로고    scopus 로고
    • Orienting and reorienting: the locus coeruleus mediates cognition through arousal
    • Sara S.J., Bouret S. Orienting and reorienting: the locus coeruleus mediates cognition through arousal. Neuron 2012, 76:130-141.
    • (2012) Neuron , vol.76 , pp. 130-141
    • Sara, S.J.1    Bouret, S.2
  • 5
    • 79958212802 scopus 로고    scopus 로고
    • Serotonin control of sleep-wake behavior
    • Monti J.M. Serotonin control of sleep-wake behavior. Sleep Med Rev 2011, 15:269-281.
    • (2011) Sleep Med Rev , vol.15 , pp. 269-281
    • Monti, J.M.1
  • 6
    • 78349312826 scopus 로고    scopus 로고
    • GABAergic actions on cholinergic laterodorsal tegmental neurons: implications for control of behavioral state
    • Kohlmeier K.A., Kristiansen U. GABAergic actions on cholinergic laterodorsal tegmental neurons: implications for control of behavioral state. Neuroscience 2010, 171:812-829.
    • (2010) Neuroscience , vol.171 , pp. 812-829
    • Kohlmeier, K.A.1    Kristiansen, U.2
  • 8
    • 33847121297 scopus 로고    scopus 로고
    • The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness
    • Sakurai T. The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness. Nat Rev Neurosci 2007, 8:171-181.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 171-181
    • Sakurai, T.1
  • 10
    • 0036734781 scopus 로고    scopus 로고
    • Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain
    • Burazin T.C.D., Bathgate R.A.D., Macris M., Layfield S., Gundlach A.L., Tregear G.W. Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain. J Neurochem 2002, 82:1553-1557.
    • (2002) J Neurochem , vol.82 , pp. 1553-1557
    • Burazin, T.C.D.1    Bathgate, R.A.D.2    Macris, M.3    Layfield, S.4    Gundlach, A.L.5    Tregear, G.W.6
  • 14
    • 33644589069 scopus 로고    scopus 로고
    • International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides
    • Bathgate R.A.D., Ivell R., Sanborn B.M., Sherwood O.D., Summers R.J. International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides. Pharmacol Rev 2006, 58:7-31.
    • (2006) Pharmacol Rev , vol.58 , pp. 7-31
    • Bathgate, R.A.D.1    Ivell, R.2    Sanborn, B.M.3    Sherwood, O.D.4    Summers, R.J.5
  • 15
    • 15544378102 scopus 로고    scopus 로고
    • Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing
    • Sutton S.W., Bonaventure P., Kuei C., Roland B., Chen J., Nepomuceno D., Lovenberg T.W., Liu C. Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing. Neuroendocrinology 2004, 80:298-307.
    • (2004) Neuroendocrinology , vol.80 , pp. 298-307
    • Sutton, S.W.1    Bonaventure, P.2    Kuei, C.3    Roland, B.4    Chen, J.5    Nepomuceno, D.6    Lovenberg, T.W.7    Liu, C.8
  • 16
  • 17
    • 64549126926 scopus 로고    scopus 로고
    • Distribution of relaxin-3 mRNA and immunoreactivity and RXFP3-binding sites in the brain of the macaque, Macaca fascicularis
    • Ma S., Shen P.J., Sang Q., Lanciego J.L., Gundlach A.L. Distribution of relaxin-3 mRNA and immunoreactivity and RXFP3-binding sites in the brain of the macaque, Macaca fascicularis. Ann NY Acad Sci 2009, 1160:256-258.
    • (2009) Ann NY Acad Sci , vol.1160 , pp. 256-258
    • Ma, S.1    Shen, P.J.2    Sang, Q.3    Lanciego, J.L.4    Gundlach, A.L.5
  • 21
    • 38749090956 scopus 로고    scopus 로고
    • Relaxin-family peptide and receptor systems in brain: Insights from recent anatomical and functional studies
    • Ma S., Gundlach A.L. Relaxin-family peptide and receptor systems in brain: Insights from recent anatomical and functional studies. Adv Exp Med Biol 2007, 612:119-137.
    • (2007) Adv Exp Med Biol , vol.612 , pp. 119-137
    • Ma, S.1    Gundlach, A.L.2
  • 23
    • 79954614803 scopus 로고    scopus 로고
    • Nucleus incertus-an emerging modulatory role in arousal, stress and memory
    • Ryan P.J., Ma S., Olucha-Bordonau F.E., Gundlach A.L. Nucleus incertus-an emerging modulatory role in arousal, stress and memory. Neurosci Biobehav Rev 2011, 35:1326-1341.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1326-1341
    • Ryan, P.J.1    Ma, S.2    Olucha-Bordonau, F.E.3    Gundlach, A.L.4
  • 26
    • 37349043000 scopus 로고    scopus 로고
    • Developmental expression and serotonergic regulation of relaxin 3/INSL7 in the nucleus incertus of rat brain
    • Miyamoto Y., Watanabe Y., Tanaka M. Developmental expression and serotonergic regulation of relaxin 3/INSL7 in the nucleus incertus of rat brain. Regul Pept 2008, 145:54-59.
    • (2008) Regul Pept , vol.145 , pp. 54-59
    • Miyamoto, Y.1    Watanabe, Y.2    Tanaka, M.3
  • 27
    • 0035977981 scopus 로고    scopus 로고
    • Hypocretin receptor protein and mRNA expression in the dorsolateral pons of rats
    • Greco M.A., Shiromani P.J. Hypocretin receptor protein and mRNA expression in the dorsolateral pons of rats. Mol Brain Res 2001, 88:176-182.
    • (2001) Mol Brain Res , vol.88 , pp. 176-182
    • Greco, M.A.1    Shiromani, P.J.2
  • 28
    • 80555134848 scopus 로고    scopus 로고
    • Orexins increase nucleus incertus neuronal activity: implications for a possible reinforcing arousal drive
    • 104.2
    • Blasiak A., Gundlach A.L., Lewandowski M.H. Orexins increase nucleus incertus neuronal activity: implications for a possible reinforcing arousal drive. FENS Abstr 2010, 5:104.2.
    • (2010) FENS Abstr , vol.5
    • Blasiak, A.1    Gundlach, A.L.2    Lewandowski, M.H.3
  • 29
    • 84876339183 scopus 로고    scopus 로고
    • Relaxin-3 innervation of the intergeniculate leaflet of the rat thalamus-neuronal tract-tracing and in vitro electrophysiological studies
    • Blasiak A., Blasiak T., Lewandowski M.H., Hossain M.A., Wade J.D., Gundlach A.L. Relaxin-3 innervation of the intergeniculate leaflet of the rat thalamus-neuronal tract-tracing and in vitro electrophysiological studies. Eur J Neurosci 2013, 37:1284-1294.
    • (2013) Eur J Neurosci , vol.37 , pp. 1284-1294
    • Blasiak, A.1    Blasiak, T.2    Lewandowski, M.H.3    Hossain, M.A.4    Wade, J.D.5    Gundlach, A.L.6
  • 30
    • 84875379260 scopus 로고    scopus 로고
    • Neuroanatomy of the extended circadian rhythm system
    • Morin L.P. Neuroanatomy of the extended circadian rhythm system. Exp Neurol 2013, 243:4-20.
    • (2013) Exp Neurol , vol.243 , pp. 4-20
    • Morin, L.P.1
  • 31
    • 0027444838 scopus 로고
    • Processing of photic information within the intergeniculate leaflet of the lateral geniculate body: assessed by neuropeptide Y immunoreactivity in the suprachiasmatic nucleus of rats
    • Shinohara K., Tominaga K., Fukuhara C., Otori Y., Inouye S.I. Processing of photic information within the intergeniculate leaflet of the lateral geniculate body: assessed by neuropeptide Y immunoreactivity in the suprachiasmatic nucleus of rats. Neuroscience 1993, 56:813-822.
    • (1993) Neuroscience , vol.56 , pp. 813-822
    • Shinohara, K.1    Tominaga, K.2    Fukuhara, C.3    Otori, Y.4    Inouye, S.I.5
  • 36
    • 11244347812 scopus 로고    scopus 로고
    • Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7
    • Liu C., Chen J., Kuei C., Sutton S., Nepomuceno D., Bonaventure P., Lovenberg T.W. Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7. Mol Pharmacol 2005, 67:231-240.
    • (2005) Mol Pharmacol , vol.67 , pp. 231-240
    • Liu, C.1    Chen, J.2    Kuei, C.3    Sutton, S.4    Nepomuceno, D.5    Bonaventure, P.6    Lovenberg, T.W.7
  • 38
    • 31044443609 scopus 로고    scopus 로고
    • Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo
    • Bathgate R.A.D., Lin F., Hanson N.F., Otvos L., Guidolin A., Giannakis C., Bastiras S., Layfield S.L., Ferraro T., Ma S., et al. Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo. Biochemistry 2006, 45:1043-1053.
    • (2006) Biochemistry , vol.45 , pp. 1043-1053
    • Bathgate, R.A.D.1    Lin, F.2    Hanson, N.F.3    Otvos, L.4    Guidolin, A.5    Giannakis, C.6    Bastiras, S.7    Layfield, S.L.8    Ferraro, T.9    Ma, S.10
  • 44
    • 79951675001 scopus 로고    scopus 로고
    • Relaxin-3/INSL7 regulates the stress-response system in the rat hypothalamus
    • Watanabe Y., Miyamoto Y., Matsuda T., Tanaka M. Relaxin-3/INSL7 regulates the stress-response system in the rat hypothalamus. J Mol Neurosci 2011, 43:169-174.
    • (2011) J Mol Neurosci , vol.43 , pp. 169-174
    • Watanabe, Y.1    Miyamoto, Y.2    Matsuda, T.3    Tanaka, M.4
  • 47
    • 84864868683 scopus 로고    scopus 로고
    • Increased feeding and body weight gain after acute/chronic hypothalamic activation of RXFP3 by relaxin-3 and receptor-selective synthetic and rAAV-driven agonist peptides: functional and therapeutic implications
    • Ganella D.E., Ryan P.J., Bathgate R.A.D., Gundlach A.L. Increased feeding and body weight gain after acute/chronic hypothalamic activation of RXFP3 by relaxin-3 and receptor-selective synthetic and rAAV-driven agonist peptides: functional and therapeutic implications. Behav Pharmacol 2012, 23:516-525.
    • (2012) Behav Pharmacol , vol.23 , pp. 516-525
    • Ganella, D.E.1    Ryan, P.J.2    Bathgate, R.A.D.3    Gundlach, A.L.4
  • 49
  • 53
    • 13844250257 scopus 로고    scopus 로고
    • Role of angiotensin in body fluid homeostasis of mice: effect of losartan on water and NaCl intakes
    • Crews E.C., Rowland N.E. Role of angiotensin in body fluid homeostasis of mice: effect of losartan on water and NaCl intakes. Am J Physiol Regul Integr Comp Physiol 2005, 288:R638-R644.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Crews, E.C.1    Rowland, N.E.2
  • 56
    • 9744224365 scopus 로고    scopus 로고
    • Housing conditions influence the expression of food-anticipatory activity in mice
    • de Groot M.H., Rusak B. Housing conditions influence the expression of food-anticipatory activity in mice. Physiol Behav 2004, 83:447-457.
    • (2004) Physiol Behav , vol.83 , pp. 447-457
    • de Groot, M.H.1    Rusak, B.2
  • 57
    • 84863992172 scopus 로고    scopus 로고
    • Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation
    • Gallardo C.M., Gunapala K.M., King O.D., Steele A.D. Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation. PLoS One 2012, 7:e41161.
    • (2012) PLoS One , vol.7
    • Gallardo, C.M.1    Gunapala, K.M.2    King, O.D.3    Steele, A.D.4
  • 58
    • 79953127787 scopus 로고    scopus 로고
    • Single gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in mice
    • Gunapala K.M., Gallardo C.M., Hsu C.T., Steele A.D. Single gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in mice. PLoS One 2011, 6:e18377.
    • (2011) PLoS One , vol.6
    • Gunapala, K.M.1    Gallardo, C.M.2    Hsu, C.T.3    Steele, A.D.4
  • 59
    • 84880226636 scopus 로고    scopus 로고
    • Modulation of feeding by chronic rAAV expression of a relaxin-3 peptide agonist in rat hypothalamus
    • Ganella D.E., Callander G.E., Ma S., Bye C.R., Gundlach A.L., Bathgate R.A.D. Modulation of feeding by chronic rAAV expression of a relaxin-3 peptide agonist in rat hypothalamus. Gene Ther 2013, 20:703-716.
    • (2013) Gene Ther , vol.20 , pp. 703-716
    • Ganella, D.E.1    Callander, G.E.2    Ma, S.3    Bye, C.R.4    Gundlach, A.L.5    Bathgate, R.A.D.6
  • 60
    • 79960428264 scopus 로고    scopus 로고
    • Neurobiology of food anticipatory circadian rhythms
    • Mistlberger R.E. Neurobiology of food anticipatory circadian rhythms. Physiol Behav 2011, 104:535-545.
    • (2011) Physiol Behav , vol.104 , pp. 535-545
    • Mistlberger, R.E.1
  • 61
    • 35448996142 scopus 로고    scopus 로고
    • Food-elicited increases in cortical acetylcholine release require orexin transmission
    • Frederick-Duus D., Guyton M.F., Fadel J. Food-elicited increases in cortical acetylcholine release require orexin transmission. Neuroscience 2007, 149:499-507.
    • (2007) Neuroscience , vol.149 , pp. 499-507
    • Frederick-Duus, D.1    Guyton, M.F.2    Fadel, J.3
  • 62
    • 79954588384 scopus 로고    scopus 로고
    • Relaxin-3 neurons in nucleus incertus of the rat: effect on activity of psychological stress and the light-dark cycle
    • A117.2
    • Banerjee A., Shen P.-J., Gundlach A.L. Relaxin-3 neurons in nucleus incertus of the rat: effect on activity of psychological stress and the light-dark cycle. FENS Abstr 2006, 3:A117.2.
    • (2006) FENS Abstr , vol.3
    • Banerjee, A.1    Shen, P.-J.2    Gundlach, A.L.3
  • 63
    • 84878655788 scopus 로고    scopus 로고
    • Sex differences in the effects of chronic stress and food restriction on body weight gain and brain expression of CRF and relaxin-3 in rats
    • Lenglos C., Mitra A., Guevremont G., Timofeeva E. Sex differences in the effects of chronic stress and food restriction on body weight gain and brain expression of CRF and relaxin-3 in rats. Genes Brain Behav 2013, 12:370-387.
    • (2013) Genes Brain Behav , vol.12 , pp. 370-387
    • Lenglos, C.1    Mitra, A.2    Guevremont, G.3    Timofeeva, E.4
  • 64
    • 84888791809 scopus 로고    scopus 로고
    • Circadian adaptations to meal timing: neuroendocrine mechanisms
    • Patton D.F., Mistlberger R.E. Circadian adaptations to meal timing: neuroendocrine mechanisms. Front Neurosci 2013, 7:185.
    • (2013) Front Neurosci , vol.7 , pp. 185
    • Patton, D.F.1    Mistlberger, R.E.2
  • 65
    • 0035320623 scopus 로고    scopus 로고
    • Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor
    • Kojima M., Hosoda H., Matsuo H., Kangawa K. Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor. Trends Endocrinol Metab 2001, 12:118-122.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 118-122
    • Kojima, M.1    Hosoda, H.2    Matsuo, H.3    Kangawa, K.4
  • 66
    • 0036144322 scopus 로고    scopus 로고
    • Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers
    • Lawrence C.B., Snape A.C., Baudoin F.M., Luckman S.M. Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers. Endocrinology 2002, 143:155-162.
    • (2002) Endocrinology , vol.143 , pp. 155-162
    • Lawrence, C.B.1    Snape, A.C.2    Baudoin, F.M.3    Luckman, S.M.4
  • 67
    • 70350759830 scopus 로고    scopus 로고
    • Relationship of arousal to circadian anticipatory behavior: ventromedial hypothalamus: one node in a hunger-arousal network
    • Ribeiro A.C., LeSauter J., Dupre C., Pfaff D.W. Relationship of arousal to circadian anticipatory behavior: ventromedial hypothalamus: one node in a hunger-arousal network. Eur J Neurosci 2009, 30:1730-1738.
    • (2009) Eur J Neurosci , vol.30 , pp. 1730-1738
    • Ribeiro, A.C.1    LeSauter, J.2    Dupre, C.3    Pfaff, D.W.4
  • 71
    • 84892832588 scopus 로고    scopus 로고
    • Hindbrain orexin 1 receptors influence palatable food intake, operant responding for food, and food-conditioned place preference in rats
    • Kay K., Parise E.M., Lilly N., Williams D.L. Hindbrain orexin 1 receptors influence palatable food intake, operant responding for food, and food-conditioned place preference in rats. Psychopharmacology (Berlin) 2013, 231:419-427.
    • (2013) Psychopharmacology (Berlin) , vol.231 , pp. 419-427
    • Kay, K.1    Parise, E.M.2    Lilly, N.3    Williams, D.L.4
  • 72
    • 54949141091 scopus 로고    scopus 로고
    • 1-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats
    • 1-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats. Br J Pharmacol 2008, 155:752-756.
    • (2008) Br J Pharmacol , vol.155 , pp. 752-756
    • Scopinho, A.A.1    Resstel, L.B.2    Correa, F.M.3
  • 73
    • 0034979397 scopus 로고    scopus 로고
    • Differential actions of dopamine receptor antagonism in rats upon food intake elicited by either mercaptoacetate or exposure to a palatable high-fat diet
    • Baker R.W., Osman J., Bodnar R.J. Differential actions of dopamine receptor antagonism in rats upon food intake elicited by either mercaptoacetate or exposure to a palatable high-fat diet. Pharmacol Biochem Behav 2001, 69:201-208.
    • (2001) Pharmacol Biochem Behav , vol.69 , pp. 201-208
    • Baker, R.W.1    Osman, J.2    Bodnar, R.J.3
  • 74
    • 58549086111 scopus 로고    scopus 로고
    • Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking
    • Pratt W.E., Blackstone K. Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking. Behav Brain Res 2009, 198:252-257.
    • (2009) Behav Brain Res , vol.198 , pp. 252-257
    • Pratt, W.E.1    Blackstone, K.2
  • 79
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler E.J., Carlezon W.A. The mesolimbic dopamine reward circuit in depression. Biol Psychiatry 2006, 59:1151-1159.
    • (2006) Biol Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon, W.A.2
  • 80
    • 84861936797 scopus 로고    scopus 로고
    • Whole-brain mapping of direct inputs to midbrain dopamine neurons
    • Watabe-Uchida M., Zhu L., Ogawa S.K., Vamanrao A., Uchida N. Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron 2012, 74:858-873.
    • (2012) Neuron , vol.74 , pp. 858-873
    • Watabe-Uchida, M.1    Zhu, L.2    Ogawa, S.K.3    Vamanrao, A.4    Uchida, N.5
  • 81
    • 84870986573 scopus 로고    scopus 로고
    • Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice
    • Kudo T., Uchigashima M., Miyazaki T., Konno K., Yamasaki M., Yanagawa Y., Minami M., Watanabe M. Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice. J Neurosci 2012, 32:18035-18046.
    • (2012) J Neurosci , vol.32 , pp. 18035-18046
    • Kudo, T.1    Uchigashima, M.2    Miyazaki, T.3    Konno, K.4    Yamasaki, M.5    Yanagawa, Y.6    Minami, M.7    Watanabe, M.8
  • 84
    • 84886022824 scopus 로고    scopus 로고
    • Relaxin-3/RXFP3 signaling and neuroendocrine function-a perspective on extrinsic hypothalamic control
    • Ganella D.E., Ma S., Gundlach A.L. Relaxin-3/RXFP3 signaling and neuroendocrine function-a perspective on extrinsic hypothalamic control. Front Endocrinol (Lausanne) 2013, 4:128.
    • (2013) Front Endocrinol (Lausanne) , vol.4 , pp. 128
    • Ganella, D.E.1    Ma, S.2    Gundlach, A.L.3
  • 85
    • 84901496570 scopus 로고    scopus 로고
    • Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior
    • Fox J.H., Lowry C.A. Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior. Front Neurosci 2013, 7:169.
    • (2013) Front Neurosci , vol.7 , pp. 169
    • Fox, J.H.1    Lowry, C.A.2
  • 86
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V., Nestler E.J. The molecular neurobiology of depression. Nature 2008, 455:894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 88
    • 84897929309 scopus 로고    scopus 로고
    • Relaxin-3/RXFP3 networks: an emerging target for the treatment of depression and other neuropsychiatric diseases?
    • Smith C.M., Walker A.W., Hosken I.T., Chua B.E., Zhang C., Haidar M., Gundlach A.L. Relaxin-3/RXFP3 networks: an emerging target for the treatment of depression and other neuropsychiatric diseases?. Front Pharmacol 2014, 5:46.
    • (2014) Front Pharmacol , vol.5 , pp. 46
    • Smith, C.M.1    Walker, A.W.2    Hosken, I.T.3    Chua, B.E.4    Zhang, C.5    Haidar, M.6    Gundlach, A.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.