Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson's disease mouse model

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Doo, Ah Reum ^a   Kim, Seung Nam ^a   Hahm, Dae Hyun ^a   Yoo, Hye H ^b   Park, Ji Yeun ^a   Lee, Hyejung ^a   Jeon, Songhee ^c   Kim, Jongpil ^c   Park, Seong Uk ^a,d   Park, Hi Joon ^a  

^a Kyung Hee University   (South Korea)

^b Hanyang University   (South Korea)

^c Dongguk University   (South Korea)

^d Kyung Hee University College of Medicine   (South Korea)

Author keywords

ERK1 2; FosB; Gastrodia elata blum; Levodopa induced dyskinesia; Parkinson's disease

Indexed keywords

AMANTADINE; GASTRODIA ELATA EXTRACT; GASTRODIN; LEVODOPA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOPAMINE; TRANSCRIPTION FACTOR FOSB; DOPAMINE; FOSB PROTEIN, MOUSE; PLANT EXTRACT; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG MECHANISM; DYSKINESIA; ENZYME PHOSPHORYLATION; GASTRODIA ELATA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMEDIATE EARLY GENE; IMMUNOHISTOLOGY; LEVODOPA INDUCED DYSKINESIA; LOCOMOTION; LONG TERM CARE; MALE; MOUSE; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; DYSKINESIA, DRUG-INDUCED; GASTRODIA; METABOLISM; PARKINSONIAN DISORDERS; PHYTOTHERAPY; SIGNAL TRANSDUCTION;

ANIMALS; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DOPAMINE; DYSKINESIA, DRUG-INDUCED; GASTRODIA; LEVODOPA; MALE; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; OXIDOPAMINE; PARKINSON DISEASE; PARKINSONIAN DISORDERS; PHYTOTHERAPY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-FOS;

EID: 84899133012     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-107     Document Type: Article

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