Resistotype of Helicobacter pylori isolates: The impact on eradication outcome

Journal of Medical Microbiology

Volumn 63, Issue PART 5, 2014, Pages 703-709

  Alfizah, Hanafiah ^a   Norazah, Ahmad ^b   Hamizah, Razlan ^a   Ramelah, Mohamed ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; BACTERIAL DNA; CIPROFLOXACIN; CLARITHROMYCIN; LEVOFLOXACIN; METRONIDAZOLE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; DNA SEQUENCE; DRUG EFFICACY; EPSILOMETER TEST; ERADICATION THERAPY; FRAMESHIFT MUTATION; FRXA GENE; GYRA GENE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MEDICAL RECORD REVIEW; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NONSENSE MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RDXA GENE; STOP CODON; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; FEMALE; GENES, BACTERIAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84899131435     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.069781-0     Document Type: Article

References (35)

1. Ahmad, N., Zakaria, W. R., Abdullah, S. A. & Mohamed, R. (2009). Characterization of clarithromycin resistance in Malaysian isolates of Helicobacter pylori. World J Gastroenterol 15, 3161-3165.
2. Ahmad, N, Zakaria, W. R. & Mohamed, R. (2011). Analysis of antibiotic susceptibility patterns of Helicobacter pylori isolates from Malaysia. Helicobacter 16, 47-51.
3. Atherton, J. C. (2006). The pathogenesis of Helicobacter pyloriinduced gastro-duodenal diseases. Annu Rev Pathol 1, 63-96.
4. Bago, J, Majstorović, K., Belosić-Halle, Z., Kućisec, N., Bakula, V., Tomić, M., Bago, P. & Troskot, R. (2010). Antimicrobial resistance of H. pylori to the outcome of 10-days vs. 7-days moxifloxacin based therapy for the eradication: a randomized controlled trial. Ann Clin Microbiol Antimicrob 9, 13.
5. Cattoir, V, Nectoux, J., Lascols, C., Deforges, L., Delchier, J. C., Megraud, F., Soussy, C. J. & Cambau, E. (2007). Update on fluoroquinolone resistance in Helicobacter pylori: new mutations leading to resistance and first description of a gyrA polymorphism associated with hypersusceptibility. Int J Antimicrob Agents 29, 389-396.
6. Chisholm, S. A. & Owen, R. J. (2003). Mutations in Helicobacter pylori rdxA gene sequences may not contribute to metronidazole resistance. J Antimicrob Chemother 51, 995-999.
7. Chisholm, S. A. & Owen, R. J. (2004). Frameshift mutations in frxA occur frequently and do not provide a reliable marker for metronidazole resistance in UK isolates of Helicobacter pylori. J Med Microbiol 53, 135-140.
8. Chisholm, S. A. & Owen, R. J. (2009). Frequency and molecular characteristics of ciprofloxacin- and rifampicin-resistant Helicobacter pylori from gastric infections in the UK. J Med Microbiol 58, 1322-1328.
9. De Francesco, V., Margiotta, M., Zullo, A., Hassan, C., Giorgio, F., Burattini, O., Stoppino, G., Cea, U., Pace, A. & other authors (2007). Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy. J Antimicrob Chemother 59, 783-785.
10. De Francesco, V., Giorgio, F., Hassan, C., Manes, G., Vannella, L., Panella, C., Ierardi, E. & Zullo, A. (2010a). Worldwide H. pylori antibiotic resistance: a systematic review. J Gastrointestin Liver Dis 19, 409-414.
11. De Francesco, V., Zullo, A., Ierardi, E., Giorgio, F., Perna, F., Hassan, C., Morini, S., Panella, C. & Vaira, D. (2010b). Phenotypic and genotypic Helicobacter pylori clarithromycin resistance and therapeutic outcome: benefits and limits. J Antimicrob Chemother 65, 327-332.
12. Debets-Ossenkopp, Y. J., Herscheid, A. J., Pot, R. G. J., Kuipers, E. J., Kusters, J. G. & Vandenbroucke-Grauls, C. M. (1999). Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxycillin, tetracycline and trovafloxacin in The Netherlands. J Antimicrob Chemother 43, 511-515.
13. Gisbert, J. P. (2009). Second-line rescue therapy of Helicobacter pylori infection. Therap Adv Gastroenterol 2, 331-356.
14. Hwang, T. J., Kim, N., Kim, H. B., Lee, B. H., Nam, R. H., Park, J. H., Lee, M. K., Park, Y. S., Lee, D. H. & other authors (2010). Change in antibiotic resistance of Helicobacter pylori strains and the effect of A2143G point mutation of 23S rRNA on the eradication of H. pylori in a single center of Korea. J Clin Gastroenterol 44, 536-543.
15. Kim, J. J., Reddy, R., Lee, M., Kim, J. G., El-Zaatari, F. A., Osato, M. S., Graham, D. Y. & Kwon, D. H. (2001). Analysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from Korea. J Antimicrob Chemother 47, 459-461.
16. Kim, J. M., Kim, J. S., Jung, H. C., Kim, N., Kim, Y. J. & Song, I. S. (2004). Distribution of antibiotic MICs for Helicobacter pylori strains over a 16-year period in patients from Seoul, South Korea. Antimicrob Agents Chemother 48, 4843-4847.
17. Kim, J. M., Kim, J. S., Kim, N., Jung, H. C. & Song, I. S. (2005). Distribution of fluoroquinolone MICs in Helicobacter pylori strains from Korean patients. J Antimicrob Chemother 56, 965-967.
18. Kim, J. M., Kim, J. S., Kim, N., Kim, Y. J., Kim, I. Y., Chee, Y. J., Lee, C. H. & Jung, H. C. (2008). Gene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients. J Microbiol Biotechnol 18, 1584-1589.
19. Kobayashi, I, Murakami, K., Kato, M., Kato, S., Azuma, T., Takahashi, S., Uemura, N., Katsuyama, T., Fukuda, Y. & other authors (2007). Changing antimicrobial susceptibility epidemiology of Helicobacter pylori strains in Japan between 2002 and 2005. J Clin Microbiol 45, 4006-4010.
20. Kwon, D. H., El-Zaatari, F. A., Kato, M., Osato, M. S., Reddy, R., Yamaoka, Y. & Graham, D. Y. (2000). Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori. Antimicrob Agents Chemother 44, 2133-2142.
21. Lee, J. H., Shin, J. H., Roe, I. H., Sohn, S. G., Lee, J. H., Kang, G. H., Lee, H. K., Jeong, B. C. & Lee, S. H. (2005). Impact of clarithromycin resistance on eradication of Helicobacter pylori in infected adults. Antimicrob Agents Chemother 49, 1600-1603.
22. Llanes, R, Soria, C., Nagashima, S., Kobayashi, N., Gala, A., Guzmán, D., Feliciano, O., Valdés, L., Gutiérrez, O. & other authors (2010). Phenotypic and genetic characterization of antimicrobial profiles of Helicobacter pylori strains in Cuba. J Health Popul Nutr 28, 124-129.
23. Malfertheiner, P, Megraud, F., O'Morain, C., Bazzoli, F., El-Omar, E., Graham, D., Hunt, R., Rokkas, T., Vakil, N. & Kuipers, E. J. (2007). Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 56, 772-781.
24. Marais, A, Bilardi, C., Cantet, F., Mendz, G. L. & Mégraud, F. (2003). Characterization of the genes rdxA and frxA involved in metronidazole resistance in Helicobacter pylori. Res Microbiol 154, 137-144.
25. Matteo, M. J., Pérez, C. V., Domingo, M. R., Olmos, M., Sanchez, C. & Catalano, M. (2006). DNA sequence analysis of rdxA and frxA from paired metronidazole-sensitive and -resistant Helicobacter pylori isolates obtained from patients with heteroresistance. Int J Antimicrob Agents 27, 152-158.
26. Mégraud, F. (2004). H pylori antibiotic resistance: prevalence, importance, and advances in testing. Gut 53, 1374-1384.
27. Mégraud, F. & Lehours, P. (2007). Helicobacter pylori detection and antimicrobial susceptibility testing. Clin Microbiol Rev 20, 280-322.
28. Ministry of Health Malaysia (2008). National Antibiotic Guideline. Putrajaya: Ministry of Health Malaysia.
29. Nahar, S., Mukhopadhyay, A. K., Khan, R., Ahmad, M. M., Datta, S., Chattopadhyay, S., Dhar, S. C., Sarker, S. A., Engstrand, L. & other authors (2004). Antimicrobial susceptibility of Helicobacter pylori strains isolated in Bangladesh. J Clin Microbiol 42, 4856-4858.
30. Rajper, S, Khan, E., Ahmad, Z., Alam, S. M. Z., Akbar, A. & Hasan, R. (2012). Macrolide and fluoroquinolone resistance in Helicobacter pylori isolates: an experience at a tertiary care centre in Pakistan. J Pak Med Assoc 62, 1140-1144.
31. Seck, A, Mbengue, M., Gassama-Sow, A., Diouf, L., Ka, M. M. & Boye, C. S. B. (2009). Antibiotic susceptibility of Helicobacter pylori isolates in Dakar, Senegal. J Infect Dev Ctries 3, 137-140.
32. Solcà, N. M., Bernasconi, M. V. & Piffaretti, J. C. (2000). Mechanism of metronidazole resistance in Helicobacter pylori: comparison of the rdxA gene sequences in 30 strains. Antimicrob Agents Chemother 44, 2207-2210.
33. Sun, Q. J., Liang, X., Zheng, Q., Gu, W. Q., Liu, W. Z., Xiao, S. D. & Lu, H. (2010). Resistance of Helicobacter pylori to antibiotics from 2000 to 2009 in Shanghai. World J Gastroenterol 16, 5118-5121.
34. Tankovic, J, Lascols, C., Sculo, Q., Petit, J. C. & Soussy, C. J. (2003). Single and double mutations in gyrA but not in gyrB are associated with low- and high-level fluoroquinolone resistance in Helicobacter pylori. Antimicrob Agents Chemother 47, 3942-3944.
35. Wueppenhorst, N, Stueger, H. P., Kist, M. & Glocker, E. (2009). Identification and molecular characterization of triple- and quadruple- resistant Helicobacter pylori clinical isolates in Germany. J Antimicrob Chemother 63, 648-653.