-
2
-
-
0028227567
-
An audit of the treatment of cancer of the oesophagus
-
Sagar PM, Gauperaa T, Sue-Ling H, McMahon MJ, Johnston D. An audit of the treatment of cancer of the oesophagus. Gut. 1994;35:941-5. (Pubitemid 24202724)
-
(1994)
Gut
, vol.35
, Issue.7
, pp. 941-945
-
-
Sagar, P.M.1
Gauperaa, T.2
Sue-Ling, H.3
McMahon, M.J.4
Johnston, D.5
-
3
-
-
0028579733
-
Oncogenes and the strategy of growth factors
-
Baserga R. Oncogenes and the strategy of growth factors. Cell. 1994;79:927-30.
-
(1994)
Cell
, vol.79
, pp. 927-930
-
-
Baserga, R.1
-
4
-
-
0027366338
-
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
-
DOI 10.1073/pnas.90.23.11217
-
Sell C, RubiniM, Rubin R, Liu JP, Efstratiadis A, Baserga R. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci U S A. 1993;90:11217-21. (Pubitemid 23354400)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11217-11221
-
-
Sell, C.1
Rubini, M.2
Rubin, R.3
Liu, J.-P.4
Efstratiadis, A.5
Baserga, R.6
-
5
-
-
0022800838
-
Insulin-like growth factor i receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
-
Ullrich A, Gray A, Tam AW, Yang-Feng T, TsubokawaM, Collins C, et al. Insulin-like growth factor i receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. Embo J. 1986;5:2503-12.
-
(1986)
Embo J
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
Yang-Feng, T.4
Tsubokawa, M.5
Collins, C.6
-
6
-
-
0034692430
-
Role of the insulin-like growth factor family in cancer development and progression
-
Yu H, Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst. 2000;92:1472-89.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1472-1489
-
-
Yu, H.1
Rohan, T.2
-
7
-
-
0026731217
-
Des-(1-3)-IGF-I, an insulin-like growth factor analog used to mimic a potential IGF-II autocrine loop, promotes the differentiation of human colon-carcinoma cells
-
DOI 10.1002/ijc.2910520614
-
Remacle-Bonnet M, Garrouste F, el Atiq F, Roccabianca M, Marvaldi J, Pommier G. Des-(1-3)-igf-i, an insulin-like growth factor analog used to mimic a potential igf-ii autocrine loop, promotes the differentiation of human colon-carcinoma cells. Int J Cancer. 1992;52:910-7. (Pubitemid 23009508)
-
(1992)
International Journal of Cancer
, vol.52
, Issue.6
, pp. 910-917
-
-
Remacle-Bonnet, M.1
Garrouste, F.2
El, A.F.3
Roccabianca, M.4
Marvaldi, J.5
Pommier, G.6
-
8
-
-
0033531765
-
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
-
Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (igf)-i and igf-binding protein-3. J Natl Cancer Inst. 1999;91:620-5. (Pubitemid 29194048)
-
(1999)
Journal of the National Cancer Institute
, vol.91
, Issue.7
, pp. 620-625
-
-
Ma, J.1
Pollak, M.N.2
Giovannucci, E.3
Chan, J.M.4
Tao, Y.5
Hennekens, C.H.6
Stampfer, M.J.7
-
9
-
-
33644506750
-
Soluble igf2 receptor rescues apc(min/+) intestinal adenoma progresion induced by igf2 loss of imprinting
-
Harper J, Burns JL, Foulstone EJ, Pignatelli M, Zaina S, Hassan AB. Soluble igf2 receptor rescues apc(min/+) intestinal adenoma progresion induced by igf2 loss of imprinting. Cancer Res. 2006;66:1940-8.
-
(2006)
Cancer Res
, vol.66
, pp. 1940-1948
-
-
Harper, J.1
Burns, J.L.2
Foulstone, E.J.3
Pignatelli, M.4
Zaina, S.5
Hassan, A.B.6
-
10
-
-
0032559272
-
Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
-
DOI 10.1126/science.279.5350.563
-
Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilkinson P, et al. Plasma insulin-like growth factor-i and prostate cancer risk: a prospective study. Science. 1998;279:563-6. (Pubitemid 28067285)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 563-566
-
-
Chan, J.M.1
Stampfer, M.J.2
Giovannucci, E.3
Gann, P.H.4
Ma, J.5
Wilkinson, P.6
Hennekens, C.H.7
Pollak, M.8
-
11
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
DOI 10.1016/0092-8674(93)90679-K
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor i (igf-1) and type 1 igf receptor (igf1r). Cell. 1993;75:59-72. (Pubitemid 23306021)
-
(1993)
Cell
, vol.75
, Issue.1
, pp. 59-72
-
-
Liu, J.-P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
12
-
-
0028086807
-
Characterization of insulin-like growth factor i receptors in human esophageal epithelial cells
-
Vinayek R, Pichney LS, Tantry U, Dutta SK, Resau J, Vengurlekar S. Characterization of insulin-like growth factor i receptors in human esophageal epithelial cells. Am J Physiol. 1994;267:G105-14.
-
(1994)
Am J Physiol
, vol.267
-
-
Vinayek, R.1
Pichney, L.S.2
Tantry, U.3
Dutta, S.K.4
Resau, J.5
Vengurlekar, S.6
-
13
-
-
0031147784
-
EGF and IGF-I synergistically stimulate proliferation of human esophageal epithelial cells
-
DOI 10.1006/jsre.1997.5080
-
Qureshi FG, Tchorzewski MT, Duncan MD, Harmon JW. Egf and igf-i synergistically stimulate proliferation of human esophageal epithelial cells. J Surg Res. 1997;69:354-8. (Pubitemid 27317881)
-
(1997)
Journal of Surgical Research
, vol.69
, Issue.2
, pp. 354-358
-
-
Qureshi, F.G.1
Tchorzewski, M.T.2
Duncan, M.D.3
Harmon, J.W.4
-
14
-
-
0032146677
-
Role of insulin-like growth factor-I in esophageal mucosal healing processes
-
Tchorzewski MT, Qureshi FG, Duncan MD, Duncan KL, Saini N, Harmon JW. Role of insulin-like growth factor-i in esophageal mucosal healing processes. J Lab Clin Med. 1998;132:134-41. (Pubitemid 28378842)
-
(1998)
Journal of Laboratory and Clinical Medicine
, vol.132
, Issue.2
, pp. 134-141
-
-
Tchorzewski, M.T.1
Qureshi, F.G.2
Duncan, M.D.3
Duncan, K.L.K.4
Saini, N.5
Harmon, J.W.6
-
15
-
-
0023951526
-
Free insulin-like growth factor i (igf-i) and igf-ii in human saliva
-
Costigan DC, Guyda HJ, Posner BI. Free insulin-like growth factor i (igf-i) and igf-ii in human saliva. J Clin Endocrinol Metab. 1988;66:1014-8.
-
(1988)
J Clin Endocrinol Metab
, vol.66
, pp. 1014-1018
-
-
Costigan, D.C.1
Guyda, H.J.2
Posner, B.I.3
-
16
-
-
10544239103
-
Relaxation of insulin-like growth factor 2 gene imprinting in esophageal cancer
-
DOI 10.1002/(SICI)1097-0215(19961115)68:4<441::AID
-
Mori M, Inoue H, Shiraishi T, Mimori K, Shibuta K, Nakashima H, et al. Relaxation of insulin-like growth factor 2 gene imprinting in esophageal cancer. Int J Cancer. 1996;68:441-6. (Pubitemid 26414497)
-
(1996)
International Journal of Cancer
, vol.68
, Issue.4
, pp. 441-446
-
-
Mori, M.1
Inoue, H.2
Shiraishi, T.3
Mimori, K.4
Shibuta, K.5
Nakashima, H.6
Mafune, K.7
Tanaka, Y.8
Ueo, H.9
Barnard, G.F.10
Sugimachi, K.11
Akiyoshi, T.12
-
17
-
-
1842847423
-
Autocrine stimulation by insulin-like growth factor i is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells
-
Liu YC, Leu CM, Wong FH, Fong WS, Chen SC, Chang C, et al. Autocrine stimulation by insulin-like growth factor i is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells. J Biomed Sci. 2002;9:665-74.
-
(2002)
J Biomed Sci
, vol.9
, pp. 665-674
-
-
Liu, Y.C.1
Leu, C.M.2
Wong, F.H.3
Fong, W.S.4
Chen, S.C.5
Chang, C.6
-
18
-
-
0042889104
-
Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas
-
DOI 10.1016/S0046-8177(03)00291-0
-
Ouban A, Muraca P, Yeatman T, Coppola D. Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas. Hum Pathol. 2003;34:803-8. (Pubitemid 37040618)
-
(2003)
Human Pathology
, vol.34
, Issue.8
, pp. 803-808
-
-
Ouban, A.1
Muraca, P.2
Yeatman, T.3
Coppola, D.4
-
19
-
-
0025892573
-
Overexpression of epidermal growth factor and insulin-like growth factor-i receptors and autocrine stimulation in human esophageal carcinoma cells
-
Chen SC, Chou CK, Wong FH, Chang CM, Hu CP. Overexpression of epidermal growth factor and insulin-like growth factor-i receptors and autocrine stimulation in human esophageal carcinoma cells. Cancer Res. 1991;51:1898-903.
-
(1991)
Cancer Res
, vol.51
, pp. 1898-1903
-
-
Chen, S.C.1
Chou, C.K.2
Wong, F.H.3
Chang, C.M.4
Hu, C.P.5
-
20
-
-
7444270714
-
Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3
-
DOI 10.1158/0008-5472.CAN-04-0715
-
Takaoka M, Harada H, Andl CD, Oyama K, Naomoto Y, Dempsey KL, et al. Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3. Cancer Res. 2004;64:7711-23. (Pubitemid 39446902)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7711-7723
-
-
Takaoka, M.1
Harada, H.2
Andl, C.D.3
Oyama, K.4
Naomoto, Y.5
Dempsey, K.L.6
Klein-Szanto, A.J.7
El-Deiry, W.S.8
Grimberg, A.9
Nakagawa, H.10
-
21
-
-
34447095442
-
Insulin-like growth factor-I receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma
-
DOI 10.1093/carcin/bgl247
-
Imsumran A, Adachi Y, Yamamoto H, Li R, Wang Y, Min Y, et al. Insulin-like growth factor-i receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma. Carcinogenesis. 2007;28:947-56. (Pubitemid 47072177)
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 947-956
-
-
Imsumran, A.1
Adachi, Y.2
Yamamoto, H.3
Li, R.4
Wang, Y.5
Min, Y.6
Piao, W.7
Nosho, K.8
Arimura, Y.9
Shinomura, Y.10
Hosokawa, M.11
Lee, C.-T.12
Carbone, D.P.13
Imai, K.14
-
22
-
-
84856764349
-
Igf-1 and its receptor in esophageal cancer: Association with adenocarcinoma and visceral obesity
-
Doyle SL, Donohoe CL, Finn SP, Howard JM, Lithander FE, Reynolds JV, et al. Igf-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity. Am J Gastroenterol. 2012;107:196-204.
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 196-204
-
-
Doyle, S.L.1
Donohoe, C.L.2
Finn, S.P.3
Howard, J.M.4
Lithander, F.E.5
Reynolds, J.V.6
-
23
-
-
84856426428
-
Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma
-
Donohoe CL, Doyle SL, McGarrigle S, CathcartMC, Daly E, O'Grady A, et al. Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma. Br J Surg. 2012;99:387-96.
-
(2012)
Br J Surg
, vol.99
, pp. 387-396
-
-
Donohoe, C.L.1
Doyle, S.L.2
McGarrigle, S.3
Cathcart, M.C.4
Daly, E.5
O'Grady, A.6
-
24
-
-
0242624594
-
Growth factor receptors as therapeutic targets: Strategies to inhibit the insulin-like growth factor I receptor
-
Surmacz E. Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor i receptor. Oncogene. 2003;22:6589-97. (Pubitemid 37372339)
-
(2003)
Oncogene
, vol.22
, Issue.43
, pp. 6589-6597
-
-
Surmacz, E.1
-
25
-
-
17144416483
-
In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors
-
DOI 10.1158/1078-0432.CCR-04-1586
-
Wu JD, Odman A, Higgins LM, Haugk K, Vessella R, Ludwig DL, et al. In vivo effects of the human type i insulin-like growth factor receptor antibody a12 on androgen-dependent and androgen-independent xenograft human prostate tumors. Clin Cancer Res. 2005;11:3065-74. (Pubitemid 40525213)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.8
, pp. 3065-3074
-
-
Wu, J.D.1
Odman, A.2
Higgins, L.M.3
Haugk, K.4
Vessella, R.5
Ludwig, D.L.6
Plymate, S.R.7
-
26
-
-
20144386856
-
Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871
-
DOI 10.1158/1078-0432.CCR-04-1070
-
Cohen BD, Baker DA, SoderstromC, Tkalcevic G, Rossi AM, Miller PE, et al. Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody cp-751,871. Clin Cancer Res. 2005;11:2063-73. (Pubitemid 40471873)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.5
, pp. 2063-2073
-
-
Cohen, B.D.1
Baker, D.A.2
Soderstrom, C.3
Tkalcevic, G.4
Rossi, A.M.5
Miller, P.E.6
Tengowski, M.W.7
Wang, F.8
Gualberto, A.9
Beebe, J.S.10
Moyer, J.D.11
-
27
-
-
12144285705
-
In vivo antitumor activity of NVP-AEW541 - A novel, potent, and selective inhibitor of the IGF-IR kinase
-
DOI 10.1016/S1535-6108(04)00051-0, PII S1535610804000510
-
Garcia-Echeverria C, Pearson MA, Marti A, Meyer T, Mestan J, Zimmermann J, et al. In vivo antitumor activity of nvp-aew541-a novel, potent, and selective inhibitor of the igf-ir kinase. Cancer Cell. 2004;5:231-9. (Pubitemid 38402115)
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 231-239
-
-
Garcia-Echeverria, C.1
Pearson, M.A.2
Marti, A.3
Meyer, T.4
Mestan, J.5
Zimmermann, J.6
Gao, J.7
Brueggen, J.8
Capraro, H.-G.9
Cozens, R.10
Evans, D.B.11
Fabbro, D.12
Furet, P.13
Porta, D.G.14
Liebetanz, J.15
Martiny-Baron, G.16
Ruetz, S.17
Hofmann, F.18
-
28
-
-
12144290914
-
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
-
DOI 10.1016/S1535-6108(04)00050-9, PII S1535610804000509
-
Mitsiades CS, Mitsiades NS, McMullan CJ, Poulaki V, Shringarpure R, Akiyama M, et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell. 2004;5:221-30. (Pubitemid 38402114)
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 221-230
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
Poulaki, V.4
Shringarpure, R.5
Akiyama, M.6
Hideshima, T.7
Chauhan, D.8
Joseph, M.9
Libermann, T.A.10
Garcia-Echeverria, C.11
Pearson, M.A.12
Hofmann, F.13
Anderson, K.C.14
Kung, A.L.15
-
29
-
-
0028265209
-
Dominant negative inhibition of tumorigenesis in vivo by human insulin- like growth factor i receptor mutant
-
Prager D, Li HL, Asa S, Melmed S. Dominant negative inhibition of tumorigenesis in vivo by human insulin- like growth factor i receptor mutant. Proc Natl Acad Sci U S A. 1994;91:2181-5.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 2181-2185
-
-
Prager, D.1
Li, H.L.2
Asa, S.3
Melmed, S.4
-
30
-
-
0029791877
-
A soluble insulin-like growth factor I receptor that induces apoptosis of tumor Cells in vivo and inhibits tumorigenesis
-
D'Ambrosio C, Ferber A, ResnicoffM, Baserga R.A soluble insulin-like growth factor i receptor that induces apoptosis of tumor cells in vivo and inhibits tumorigenesis. Cancer Res. 1996;56:4013-20. (Pubitemid 26284753)
-
(1996)
Cancer Research
, vol.56
, Issue.17
, pp. 4013-4020
-
-
D'Ambrosio, C.1
Ferber, A.2
Resnicoff, M.3
Baserga, R.4
-
31
-
-
0036787432
-
Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines
-
Adachi Y, Lee CT, Coffee K, Yamagata N, Ohm JE, Park KH, et al. Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines. Gastroenterology. 2002;123:1191-204.
-
(2002)
Gastroenterology
, vol.123
, pp. 1191-1204
-
-
Adachi, Y.1
Lee, C.T.2
Coffee, K.3
Yamagata, N.4
Ohm, J.E.5
Park, K.H.6
-
32
-
-
0141988681
-
Genetic blockade of the insulin-like growth factor-I receptor: A promising strategy for human pancreatic cancer
-
Min Y, Adachi Y, Yamamoto H, Ito H, Itoh F, Lee CT, et al. Genetic blockade of the insulin-like growth factor-i receptor: a promising strategy for human pancreatic cancer. Cancer Res. 2003;63:6432-41. (Pubitemid 37255193)
-
(2003)
Cancer Research
, vol.63
, Issue.19
, pp. 6432-6441
-
-
Min, Y.1
Adachi, Y.2
Yamamoto, H.3
Ito, H.4
Itoh, F.5
Lee, C.-T.6
Nadaf, S.7
Carbone, D.P.8
Imai, K.9
-
33
-
-
0037277323
-
Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer
-
DOI 10.1038/sj.cgt.7700524
-
Lee CT, Park KH, Adachi Y, Seol JY, Yoo CG, Kim YW, et al. Recombinant adenoviruses expressing dominant negative insulin-like growth factor-i receptor demonstrate antitumor effects on lung cancer. Cancer Gene Ther. 2003;10:57-63. (Pubitemid 36222077)
-
(2003)
Cancer Gene Therapy
, vol.10
, Issue.1
, pp. 57-63
-
-
Lee, C.-T.1
Park, K.-H.2
Adachi, Y.3
Seol, J.Y.4
Yoo, C.-G.5
Kim, Y.W.6
Han, S.K.7
Shim, Y.-S.8
Coffee, K.9
Dikov, M.M.10
Carbone, D.P.11
-
34
-
-
20244366701
-
Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts
-
DOI 10.1136/gut.2004.048926
-
Min Y, Adachi Y, Yamamoto H, Imsumran A, Arimura Y, Endo T, et al. Insulin-like growth factor i receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts. Gut. 2005;54:591-600. (Pubitemid 40559239)
-
(2005)
Gut
, vol.54
, Issue.5
, pp. 591-600
-
-
Min, Y.1
Adachi, Y.2
Yamamoto, H.3
Imsumran, A.4
Arimura, Y.5
Endo, T.6
Hinoda, Y.7
Lee, C.-T.8
Nadaf, S.9
Carbone, D.P.10
Imai, K.11
-
35
-
-
84856412030
-
Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers
-
Ohashi H, Adachi Y, Yamamoto H, Taniguchi H, Nosho K, Suzuki H, et al. Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers. Cancer Sci. 2012;103:252-61.
-
(2012)
Cancer Sci
, vol.103
, pp. 252-261
-
-
Ohashi, H.1
Adachi, Y.2
Yamamoto, H.3
Taniguchi, H.4
Nosho, K.5
Suzuki, H.6
-
36
-
-
77949268291
-
Targeting for insulin-like growth factor-i receptor with short hairpin RNA for human digestive/gastrointestinal cancers
-
Wang Y, Adachi Y, Imsumran A, Yamamoto H, Piao W, Li H, et al. Targeting for insulin-like growth factor-i receptor with short hairpin RNA for human digestive/gastrointestinal cancers. J Gastroenterol. 2010;45:159-70.
-
(2010)
J Gastroenterol
, vol.45
, pp. 159-170
-
-
Wang, Y.1
Adachi, Y.2
Imsumran, A.3
Yamamoto, H.4
Piao, W.5
Li, H.6
-
37
-
-
24744437999
-
Discovery of a 1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity
-
DOI 10.1021/jm050392q
-
Wittman M, Carboni J, Attar R, Balasubramanian B, Balimane P, Brassil P, et al. Discovery of a (1h-benzoimidazol-2-yl)-1h-pyridin-2-one (bms-536924) inhibitor of insulin-like growth factor i receptor kinase with in vivo antitumor activity. J Med Chem. 2005;48:5639-43. (Pubitemid 41298335)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.18
, pp. 5639-5643
-
-
Wittman, M.1
Carboni, J.2
Attar, R.3
Balasubramanian, B.4
Balimane, P.5
Brassil, P.6
Beaulieu, F.7
Chang, C.8
Clarke, W.9
Dell, J.10
Eummer, J.11
Frennesson, D.12
Gottardis, M.13
Greer, A.14
Hansel, S.15
Hurlburt, W.16
Jacobson, B.17
Krishnananthan, S.18
Lee, F.Y.19
Li, A.20
Lin, T.-A.21
Liu, P.22
Ouellet, C.23
Sang, X.24
Saulnier, M.G.25
Stoffan, K.26
Sun, Y.27
Velaparthi, U.28
Wong, H.29
Yang, Z.30
Zimmermann, K.31
Zoeckler, M.32
Vyas, D.33
more..
-
38
-
-
33847421317
-
Adenovirus expressing shRNA to IGF-1R enhances the chemosensitivity of lung cancer cell lines by blocking IGF-1 pathway
-
DOI 10.1016/j.lungcan.2006.10.020, PII S0169500206006027
-
Lee YJ, Imsumran A, Park MY, Kwon SY, Yoon HI, Lee JH, et al. Adenovirus expressing shRNA to igf-1r enhances the chemosensitivity of lung cancer cell lines by blocking igf-1 pathway. Lung Cancer. 2007;55:279-86. (Pubitemid 46343577)
-
(2007)
Lung Cancer
, vol.55
, Issue.3
, pp. 279-286
-
-
Lee, Y.-J.1
Imsumran, A.2
Park, M.-Y.3
Kwon, S.-Y.4
Yoon, H.I.5
Lee, J.-H.6
Yoo, C.-G.7
Kim, Y.W.8
Han, S.K.9
Shim, Y.-S.10
Piao, W.11
Yamamoto, H.12
Adachi, Y.13
Carbone, D.P.14
Lee, C.-T.15
-
39
-
-
0028099302
-
Expression of insulin-like growth factors and their binding proteins in the estrogen responsive Ishikawa human endometrial cancer cell line
-
DOI 10.1210/en.135.6.2511
-
Hana V, Murphy LJ. Expression of insulin-like growth factors and their binding proteins in the estrogen responsive Ishikawa human endometrial cancer cell line. Endocrinology. 1994;135:2511-6. (Pubitemid 24377410)
-
(1994)
Endocrinology
, vol.135
, Issue.6
, pp. 2511-2516
-
-
Hana, V.1
Murphy, L.J.2
-
40
-
-
15844394554
-
Insulin-like growth factor expression in human cancer cell lines
-
DOI 10.1074/jbc.271.19.11477
-
Quinn KA, Treston AM, Unsworth EJ, Miller MJ, Vos M, Grimley C, et al. Insulin-like growth factor expression in human cancer cell lines. J Biol Chem. 1996;271:11477-83. (Pubitemid 26155990)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.19
, pp. 11477-11483
-
-
Quinn, K.A.1
Treston, A.M.2
Unsworth, E.J.3
Miller, M.-J.4
Vos, M.5
Grimley, C.6
Battey, J.7
Mulshine, J.L.8
Cuttitta, F.9
-
41
-
-
0037112511
-
Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype
-
Pennisi PA, Barr V, Nunez NP, Stannard B, Le Roith D. Reduced expression of insulin-like growth factor i receptors in mcf-7 breast cancer cells leads to a more metastatic phenotype. Cancer Res. 2002;62:6529-37. (Pubitemid 35364118)
-
(2002)
Cancer Research
, vol.62
, Issue.22
, pp. 6529-6537
-
-
Pennisi, P.A.1
Barr, V.2
Nunez, N.P.3
Stannard, B.4
Le, R.D.5
-
42
-
-
77957014139
-
Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus
-
Kalinina T, Bockhorn M, Kaifi JT, Thieltges S, Gungor C, Effenberger KE, et al. Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus. Int J Cancer. 2010;127:1931-40.
-
(2010)
Int J Cancer
, vol.127
, pp. 1931-1940
-
-
Kalinina, T.1
Bockhorn, M.2
Kaifi, J.T.3
Thieltges, S.4
Gungor, C.5
Effenberger, K.E.6
-
43
-
-
83555177355
-
Microrna-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor
-
Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, et al. Microrna-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. Gut. 2012;61:33-42.
-
(2012)
Gut
, vol.61
, pp. 33-42
-
-
Kong, K.L.1
Kwong, D.L.2
Chan, T.H.3
Law, S.Y.4
Chen, L.5
Li, Y.6
-
44
-
-
79951579534
-
Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin stability
-
Juan HC, Tsai HT, Chang PH, Huang CY, Hu CP, Wong FH. Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin stability. Apoptosis. 2011;16:174-83.
-
(2011)
Apoptosis
, vol.16
, pp. 174-183
-
-
Juan, H.C.1
Tsai, H.T.2
Chang, P.H.3
Huang, C.Y.4
Hu, C.P.5
Wong, F.H.6
-
45
-
-
34247607255
-
Pretreatment with insulin enhances anticancer functions of 5-fluorouracil in human esophageal and colonic cancer cells
-
DOI 10.1111/j.1745-7254.2007.00554.x
-
Zou K, Ju JH, Xie H. Pretreatment with insulin enhances anticancer functions of 5-fluorouracil in human esophageal and colonic cancer cells. Acta Pharmacol Sin. 2007;28:721-30. (Pubitemid 46684019)
-
(2007)
Acta Pharmacologica Sinica
, vol.28
, Issue.5
, pp. 721-730
-
-
Zou, K.1
Ju, J.-H.2
Xie, H.3
-
46
-
-
73149120253
-
Bms-754807, a small molecule inhibitor of insulin-like growth factor-1r/ir
-
Carboni JM, Wittman M, Yang Z, Lee F, Greer A, Hurlburt W, et al. Bms-754807, a small molecule inhibitor of insulin-like growth factor-1r/ir. Mol Cancer Ther. 2009;8:3341-9.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3341-3349
-
-
Carboni, J.M.1
Wittman, M.2
Yang, Z.3
Lee, F.4
Greer, A.5
Hurlburt, W.6
-
47
-
-
84865676060
-
Esophageal cancer exhibits resistance to a novel igf-1r inhibitor nvp-aew541 with maintained ras-MAPK activity
-
Bao XH, Takaoka M, Hao HF, Wang ZG, Fukazawa T, Yamatsuji T, et al. Esophageal cancer exhibits resistance to a novel igf-1r inhibitor nvp-aew541 with maintained ras-MAPK activity. Anticancer Res. 2012;32:2827-34.
-
(2012)
Anticancer Res
, vol.32
, pp. 2827-2834
-
-
Bao, X.H.1
Takaoka, M.2
Hao, H.F.3
Wang, Z.G.4
Fukazawa, T.5
Yamatsuji, T.6
-
48
-
-
49849098247
-
Insulin-like growth factor-i receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas
-
Piao W, Wang Y, Adachi Y, Yamamoto H, Li R, Imsumran A, et al. Insulin-like growth factor-i receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas. Mol Cancer Ther. 2008;7:1483-93.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1483-1493
-
-
Piao, W.1
Wang, Y.2
Adachi, Y.3
Yamamoto, H.4
Li, R.5
Imsumran, A.6
-
49
-
-
79961010790
-
The efficacy of igf-i receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status
-
Ii M, Li H, Adachi Y, Yamamoto H, Ohashi H, Taniguchi H, et al. The efficacy of igf-i receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status. Clin Cancer Res. 2011;17:5048-59.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5048-5059
-
-
Ii, M.1
Li, H.2
Adachi, Y.3
Yamamoto, H.4
Ohashi, H.5
Taniguchi, H.6
-
50
-
-
51649114600
-
Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-i receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo
-
Watanabe N, Takaoka M, Sakurama K, Tomono Y, Hatakeyama S, Ohmori O, et al. Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-i receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo. Clin Cancer Res. 2008;14:4631-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4631-4639
-
-
Watanabe, N.1
Takaoka, M.2
Sakurama, K.3
Tomono, Y.4
Hatakeyama, S.5
Ohmori, O.6
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