Targeting for insulin-like growth factor-I receptor with short hairpin RNA for human digestive/gastrointestinal cancers

Journal of Gastroenterology

Volumn 45, Issue 2, 2010, Pages 159-170

  Wang, Yu ^a   Adachi, Yasushi ^a   Imsumran, Arisa ^a   Yamamoto, Hiroyuki ^a   Piao, Wenhua ^a   Li, Hua ^a   Ii, Masanori ^a   Arimura, Yoshiaki ^a   Park, Mi Young ^b   Kim, Dalrae ^b   Lee, Choon Taek ^b   Carbone, David P ^c   Imai, Kohzoh ^a   Shinomura, Yasuhisa ^a  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

^b Seoul National University College of Medicine   (South Korea)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Combination therapy; Digestive gastrointestinal cancers; Insulin like growth factor I receptor (IGF IR); RNAi; Short hairpin RNA

Indexed keywords

ADENOVIRUS VECTOR; CISPLATIN; FLUOROURACIL; HYBRID PROTEIN; INSULIN RECEPTOR; SHORT HAIRPIN RNA; SOMATOMEDIN C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENICITY; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL EFFECTIVENESS; COLONY FORMATION; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTROINTESTINAL NEOPLASMS; GENE TARGETING; GENETIC VECTORS; HUMANS; INSULIN; MICE; MICE, INBRED BALB C; MICE, NUDE; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77949268291     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-009-0151-6     Document Type: Article

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