-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
-
10.1097/00003246-200107000-00002, 11445675
-
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001, 29(7):1303-1310. 10.1097/00003246-200107000-00002, 11445675.
-
(2001)
Crit Care Med
, vol.29
, Issue.7
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
10.1056/NEJMoa022139, 12700374
-
Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003, 348(16):1546-1554. 10.1056/NEJMoa022139, 12700374.
-
(2003)
N Engl J Med
, vol.348
, Issue.16
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
3
-
-
33744527833
-
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
-
10.1097/01.CCM.0000217961.75225.E9, 16625125
-
Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, Suppes R, Feinstein D, Zanotti S, Taiberg L, Gurka D, Cheang M. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006, 34(6):1589-1596. 10.1097/01.CCM.0000217961.75225.E9, 16625125.
-
(2006)
Crit Care Med
, vol.34
, Issue.6
, pp. 1589-1596
-
-
Kumar, A.1
Roberts, D.2
Wood, K.E.3
Light, B.4
Parrillo, J.E.5
Sharma, S.6
Suppes, R.7
Feinstein, D.8
Zanotti, S.9
Taiberg, L.10
Gurka, D.11
Cheang, M.12
-
4
-
-
0141610906
-
The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting
-
10.1378/chest.118.1.146, 10893372
-
Ibrahim EH, Sherman G, Ward S, Fraser VJ, Kollef MH. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 2000, 118(1):146-155. 10.1378/chest.118.1.146, 10893372.
-
(2000)
Chest
, vol.118
, Issue.1
, pp. 146-155
-
-
Ibrahim, E.H.1
Sherman, G.2
Ward, S.3
Fraser, V.J.4
Kollef, M.H.5
-
5
-
-
9644308127
-
New developments in the diagnosis of bloodstream infections
-
10.1016/S1473-3099(04)01205-8, 15567125
-
Peters RP, van Agtmael MA, Danner SA, Savelkoul PH, Vandenbroucke-Grauls CM. New developments in the diagnosis of bloodstream infections. Lancet Infect Dis 2004, 4(12):751-760. 10.1016/S1473-3099(04)01205-8, 15567125.
-
(2004)
Lancet Infect Dis
, vol.4
, Issue.12
, pp. 751-760
-
-
Peters, R.P.1
van Agtmael, M.A.2
Danner, S.A.3
Savelkoul, P.H.4
Vandenbroucke-Grauls, C.M.5
-
6
-
-
0032990275
-
Utility of blood cultures in community-acquired pneumonia requiring hospitalization: influence of antibiotic treatment before admission
-
10.1016/S0954-6111(99)90010-0, 10464880
-
Glerant JC, Hellmuth D, Schmit JL, Ducroix JP, Jounieaux V. Utility of blood cultures in community-acquired pneumonia requiring hospitalization: influence of antibiotic treatment before admission. Respir Med 1999, 93(3):208-212. 10.1016/S0954-6111(99)90010-0, 10464880.
-
(1999)
Respir Med
, vol.93
, Issue.3
, pp. 208-212
-
-
Glerant, J.C.1
Hellmuth, D.2
Schmit, J.L.3
Ducroix, J.P.4
Jounieaux, V.5
-
7
-
-
0023554440
-
Effect of antimicrobials on blood cultures in endocarditis
-
10.1016/0732-8893(87)90167-2, 3126019
-
McKenzie R, Reimer LG. Effect of antimicrobials on blood cultures in endocarditis. Diagn Microbiol Infect Dis 1987, 8(3):165-172. 10.1016/0732-8893(87)90167-2, 3126019.
-
(1987)
Diagn Microbiol Infect Dis
, vol.8
, Issue.3
, pp. 165-172
-
-
McKenzie, R.1
Reimer, L.G.2
-
9
-
-
84879769996
-
Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology
-
10.1093/cid/cit247, 23595835
-
Patel R. Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology. Clin Infect Dis 2013, 57(4):564-572. 10.1093/cid/cit247, 23595835.
-
(2013)
Clin Infect Dis
, vol.57
, Issue.4
, pp. 564-572
-
-
Patel, R.1
-
10
-
-
84858408842
-
Direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry improves appropriateness of antibiotic treatment of bacteremia
-
10.1371/journal.pone.0032589, 3306318, 22438880
-
Vlek AL, Bonten MJ, Boel CH. Direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry improves appropriateness of antibiotic treatment of bacteremia. PLoS One 2012, 7(3):e32589. 10.1371/journal.pone.0032589, 3306318, 22438880.
-
(2012)
PLoS One
, vol.7
, Issue.3
-
-
Vlek, A.L.1
Bonten, M.J.2
Boel, C.H.3
-
11
-
-
84866902800
-
Evaluation of a polymerase chain reaction assay for pathogen detection in septic patients under routine condition: an observational study
-
10.1371/journal.pone.0046003, 3459981, 23029360
-
Bloos F, Sachse S, Kortgen A, Pletz MW, Lehmann M, Straube E, Riedemann NC, Reinhart K, Bauer M. Evaluation of a polymerase chain reaction assay for pathogen detection in septic patients under routine condition: an observational study. PLoS One 2012, 7(9):e46003. 10.1371/journal.pone.0046003, 3459981, 23029360.
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Bloos, F.1
Sachse, S.2
Kortgen, A.3
Pletz, M.W.4
Lehmann, M.5
Straube, E.6
Riedemann, N.C.7
Reinhart, K.8
Bauer, M.9
-
12
-
-
69949087599
-
Diagnosis of bacteremia in whole-blood samples by use of a commercial universal 16S rRNA gene-based PCR and sequence analysis
-
10.1128/JCM.00567-09, 2738079, 19571030
-
Wellinghausen N, Kochem AJ, Disque C, Muhl H, Gebert S, Winter J, Matten J, Sakka SG. Diagnosis of bacteremia in whole-blood samples by use of a commercial universal 16S rRNA gene-based PCR and sequence analysis. J Clin Microbiol 2009, 47(9):2759-2765. 10.1128/JCM.00567-09, 2738079, 19571030.
-
(2009)
J Clin Microbiol
, vol.47
, Issue.9
, pp. 2759-2765
-
-
Wellinghausen, N.1
Kochem, A.J.2
Disque, C.3
Muhl, H.4
Gebert, S.5
Winter, J.6
Matten, J.7
Sakka, S.G.8
-
13
-
-
42249084460
-
A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples
-
10.1007/s00430-007-0063-0, 18008085
-
Lehmann LE, Hunfeld KP, Emrich T, Haberhausen G, Wissing H, Hoeft A, Stuber F. A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples. Med Microbiol Immunol 2008, 197(3):313-324. 10.1007/s00430-007-0063-0, 18008085.
-
(2008)
Med Microbiol Immunol
, vol.197
, Issue.3
, pp. 313-324
-
-
Lehmann, L.E.1
Hunfeld, K.P.2
Emrich, T.3
Haberhausen, G.4
Wissing, H.5
Hoeft, A.6
Stuber, F.7
-
14
-
-
84857819105
-
Accuracy of LightCycler(R) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol
-
3278490, 22240646
-
Dark P, Wilson C, Blackwood B, McAuley DF, Perkins GD, McMullan R, Gates S, Warhurst G. Accuracy of LightCycler(R) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol. BMJ Open 2012, 2(1):e000392. 3278490, 22240646.
-
(2012)
BMJ Open
, vol.2
, Issue.1
-
-
Dark, P.1
Wilson, C.2
Blackwood, B.3
McAuley, D.F.4
Perkins, G.D.5
McMullan, R.6
Gates, S.7
Warhurst, G.8
-
15
-
-
84878434234
-
Multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis - a systemic review and meta-analysis
-
10.1371/journal.pone.0062323, 3667030, 23734173
-
Chang SS, Hsieh WH, Liu TS, Lee SH, Wang CH, Chou HC, Yeo YH, Tseng CP, Lee CC. Multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis - a systemic review and meta-analysis. PLoS One 2013, 8(5):e62323. 10.1371/journal.pone.0062323, 3667030, 23734173.
-
(2013)
PLoS One
, vol.8
, Issue.5
-
-
Chang, S.S.1
Hsieh, W.H.2
Liu, T.S.3
Lee, S.H.4
Wang, C.H.5
Chou, H.C.6
Yeo, Y.H.7
Tseng, C.P.8
Lee, C.C.9
-
16
-
-
69249158125
-
Severity of pneumococcal pneumonia associated with genomic bacterial load
-
10.1378/chest.09-0258, 19433527
-
Rello J, Lisboa T, Lujan M, Gallego M, Kee C, Kay I, Lopez D, Waterer GW. Severity of pneumococcal pneumonia associated with genomic bacterial load. Chest 2009, 136(3):832-840. 10.1378/chest.09-0258, 19433527.
-
(2009)
Chest
, vol.136
, Issue.3
, pp. 832-840
-
-
Rello, J.1
Lisboa, T.2
Lujan, M.3
Gallego, M.4
Kee, C.5
Kay, I.6
Lopez, D.7
Waterer, G.W.8
-
17
-
-
79961207975
-
Quantitative rt-PCR holds promise as a screening tool for patients with severe sepsis
-
10.1111/j.1742-6723.2011.01445.x, 21824318
-
Kirkbright S, Fatovich D, Kee C, Kay I, Flexman J, Pryce TM, Waterer GW. Quantitative rt-PCR holds promise as a screening tool for patients with severe sepsis. Emerg Med Australas 2011, 23(4):502-506. 10.1111/j.1742-6723.2011.01445.x, 21824318.
-
(2011)
Emerg Med Australas
, vol.23
, Issue.4
, pp. 502-506
-
-
Kirkbright, S.1
Fatovich, D.2
Kee, C.3
Kay, I.4
Flexman, J.5
Pryce, T.M.6
Waterer, G.W.7
-
18
-
-
60549089452
-
Severity of meningococcal disease associated with genomic bacterial load
-
10.1086/596707, 19191644
-
Darton T, Guiver M, Naylor S, Jack DL, Kaczmarski EB, Borrow R, Read RC. Severity of meningococcal disease associated with genomic bacterial load. Clin Infect Dis 2009, 48(5):587-594. 10.1086/596707, 19191644.
-
(2009)
Clin Infect Dis
, vol.48
, Issue.5
, pp. 587-594
-
-
Darton, T.1
Guiver, M.2
Naylor, S.3
Jack, D.L.4
Kaczmarski, E.B.5
Borrow, R.6
Read, R.C.7
-
19
-
-
66149087199
-
High levels of mecA DNA detected by a quantitative real-time PCR assay are associated with mortality in patients with methicillin-resistant Staphylococcus aureus bacteremia
-
10.1128/JCM.01197-08, 2681853, 19279177
-
Ho YC, Chang SC, Lin SR, Wang WK. High levels of mecA DNA detected by a quantitative real-time PCR assay are associated with mortality in patients with methicillin-resistant Staphylococcus aureus bacteremia. J Clin Microbiol 2009, 47(5):1443-1451. 10.1128/JCM.01197-08, 2681853, 19279177.
-
(2009)
J Clin Microbiol
, vol.47
, Issue.5
, pp. 1443-1451
-
-
Ho, Y.C.1
Chang, S.C.2
Lin, S.R.3
Wang, W.K.4
-
20
-
-
70349640059
-
Streptococcus pneumoniae DNA load in blood as a marker of infection in patients with community-acquired pneumonia
-
10.1128/JCM.01071-09, 2756912, 19675218
-
Peters RP, de Boer RF, Schuurman T, Gierveld S, Kooistra-Smid M, van Agtmael MA, Vandenbroucke-Grauls CM, Persoons MC, Savelkoul PH. Streptococcus pneumoniae DNA load in blood as a marker of infection in patients with community-acquired pneumonia. J Clin Microbiol 2009, 47(10):3308-3312. 10.1128/JCM.01071-09, 2756912, 19675218.
-
(2009)
J Clin Microbiol
, vol.47
, Issue.10
, pp. 3308-3312
-
-
Peters, R.P.1
de Boer, R.F.2
Schuurman, T.3
Gierveld, S.4
Kooistra-Smid, M.5
van Agtmael, M.A.6
Vandenbroucke-Grauls, C.M.7
Persoons, M.C.8
Savelkoul, P.H.9
-
21
-
-
80054723483
-
Evaluation of a commercial multiplex PCR test (SeptiFast) in the etiological diagnosis of community-onset bloodstream infections
-
10.1007/s10096-011-1201-6, 21373774
-
Josefson P, Stralin K, Ohlin A, Ennefors T, Dragsten B, Andersson L, Fredlund H, Molling P, Olcen P. Evaluation of a commercial multiplex PCR test (SeptiFast) in the etiological diagnosis of community-onset bloodstream infections. Eur J Clin Microbiol Infect Dis 2011, 30(9):1127-1134. 10.1007/s10096-011-1201-6, 21373774.
-
(2011)
Eur J Clin Microbiol Infect Dis
, vol.30
, Issue.9
, pp. 1127-1134
-
-
Josefson, P.1
Stralin, K.2
Ohlin, A.3
Ennefors, T.4
Dragsten, B.5
Andersson, L.6
Fredlund, H.7
Molling, P.8
Olcen, P.9
-
22
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
-
10.1378/chest.101.6.1644, 1303622
-
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992, 101(6):1644-1655. 10.1378/chest.101.6.1644, 1303622.
-
(1992)
Chest
, vol.101
, Issue.6
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.7
Sibbald, W.J.8
-
23
-
-
76549109209
-
Improved detection of blood stream pathogens by real-time PCR in severe sepsis
-
10.1007/s00134-009-1608-z, 19756512
-
Lehmann LE, Hunfeld KP, Steinbrucker M, Brade V, Book M, Seifert H, Bingold T, Hoeft A, Wissing H, Stuber F. Improved detection of blood stream pathogens by real-time PCR in severe sepsis. Intensive Care Med 2010, 36(1):49-56. 10.1007/s00134-009-1608-z, 19756512.
-
(2010)
Intensive Care Med
, vol.36
, Issue.1
, pp. 49-56
-
-
Lehmann, L.E.1
Hunfeld, K.P.2
Steinbrucker, M.3
Brade, V.4
Book, M.5
Seifert, H.6
Bingold, T.7
Hoeft, A.8
Wissing, H.9
Stuber, F.10
-
24
-
-
79954626811
-
Diagnostic accuracy and potential clinical value of the LightCycler SeptiFast assay in the management of bloodstream infections occurring in neutropenic and critically ill patients
-
10.1016/j.ijid.2011.01.003, 21353616
-
Bravo D, Blanquer J, Tormo M, Aguilar G, Borras R, Solano C, Clari MA, Costa E, Munoz-Cobo B, Argueso M, Pineda JR, Navarro D. Diagnostic accuracy and potential clinical value of the LightCycler SeptiFast assay in the management of bloodstream infections occurring in neutropenic and critically ill patients. Int J Infect Dis 2011, 15(5):e326-e331. 10.1016/j.ijid.2011.01.003, 21353616.
-
(2011)
Int J Infect Dis
, vol.15
, Issue.5
-
-
Bravo, D.1
Blanquer, J.2
Tormo, M.3
Aguilar, G.4
Borras, R.5
Solano, C.6
Clari, M.A.7
Costa, E.8
Munoz-Cobo, B.9
Argueso, M.10
Pineda, J.R.11
Navarro, D.12
-
25
-
-
77953920184
-
Preliminary clinical study using a multiplex real-time PCR test for the detection of bacterial and fungal DNA directly in blood
-
10.1111/j.1469-0691.2009.02940.x, 19689465
-
Wallet F, Nseir S, Baumann L, Herwegh S, Sendid B, Boulo M, Roussel-Delvallez M, Durocher AV, Courcol RJ. Preliminary clinical study using a multiplex real-time PCR test for the detection of bacterial and fungal DNA directly in blood. Clin Microbiol Infect 2010, 16(6):774-779. 10.1111/j.1469-0691.2009.02940.x, 19689465.
-
(2010)
Clin Microbiol Infect
, vol.16
, Issue.6
, pp. 774-779
-
-
Wallet, F.1
Nseir, S.2
Baumann, L.3
Herwegh, S.4
Sendid, B.5
Boulo, M.6
Roussel-Delvallez, M.7
Durocher, A.V.8
Courcol, R.J.9
-
26
-
-
67651049965
-
Multiplex real-time PCR and blood culture for identification of bloodstream pathogens in patients with suspected sepsis
-
10.1111/j.1469-0691.2009.02736.x, 19392905
-
Westh H, Lisby G, Breysse F, Boddinghaus B, Chomarat M, Gant V, Goglio A, Raglio A, Schuster H, Stuber F, Wissing H, Hoeft A. Multiplex real-time PCR and blood culture for identification of bloodstream pathogens in patients with suspected sepsis. Clin Microbiol Infect 2009, 15(6):544-551. 10.1111/j.1469-0691.2009.02736.x, 19392905.
-
(2009)
Clin Microbiol Infect
, vol.15
, Issue.6
, pp. 544-551
-
-
Westh, H.1
Lisby, G.2
Breysse, F.3
Boddinghaus, B.4
Chomarat, M.5
Gant, V.6
Goglio, A.7
Raglio, A.8
Schuster, H.9
Stuber, F.10
Wissing, H.11
Hoeft, A.12
-
27
-
-
77951210696
-
A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis
-
10.1007/s00134-009-1705-z, 19924398
-
Bloos F, Hinder F, Becker K, Sachse S, Mekontso Dessap A, Straube E, Cattoir V, Brun-Buisson C, Reinhart K, Peters G, Bauer M. A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis. Intensive Care Med 2010, 36(2):241-247. 10.1007/s00134-009-1705-z, 19924398.
-
(2010)
Intensive Care Med
, vol.36
, Issue.2
, pp. 241-247
-
-
Bloos, F.1
Hinder, F.2
Becker, K.3
Sachse, S.4
Mekontso Dessap, A.5
Straube, E.6
Cattoir, V.7
Brun-Buisson, C.8
Reinhart, K.9
Peters, G.10
Bauer, M.11
-
28
-
-
23844450650
-
Time to positivity in Staphylococcus aureus bacteremia: possible correlation with the source and outcome of infection
-
10.1086/432472, 16080079
-
Khatib R, Riederer K, Saeed S, Johnson LB, Fakih MG, Sharma M, Tabriz MS, Khosrovaneh A. Time to positivity in Staphylococcus aureus bacteremia: possible correlation with the source and outcome of infection. Clin Infect Dis 2005, 41(5):594-598. 10.1086/432472, 16080079.
-
(2005)
Clin Infect Dis
, vol.41
, Issue.5
, pp. 594-598
-
-
Khatib, R.1
Riederer, K.2
Saeed, S.3
Johnson, L.B.4
Fakih, M.G.5
Sharma, M.6
Tabriz, M.S.7
Khosrovaneh, A.8
-
29
-
-
84875823959
-
The value of adding Septifast(R) to a score for predicting complicated bloodstream infections caused by Gram-positive bacteria or Candida species
-
10.1128/JCM.02882-12, 3666801, 23363819
-
Fernandez-Cruz A, Marin M, Kestler M, Alcala L, Rodriguez-Creixems M, Bouza E. The value of adding Septifast(R) to a score for predicting complicated bloodstream infections caused by Gram-positive bacteria or Candida species. J Clin Microbiol 2013, 51(4):1130-1136. 10.1128/JCM.02882-12, 3666801, 23363819.
-
(2013)
J Clin Microbiol
, vol.51
, Issue.4
, pp. 1130-1136
-
-
Fernandez-Cruz, A.1
Marin, M.2
Kestler, M.3
Alcala, L.4
Rodriguez-Creixems, M.5
Bouza, E.6
-
30
-
-
70349779856
-
Clinical impact of a commercially available multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis
-
10.1186/1471-2334-9-126, 2739209, 19671147
-
Dierkes C, Ehrenstein B, Siebig S, Linde HJ, Reischl U, Salzberger B. Clinical impact of a commercially available multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis. BMC Infect Dis 2009, 9:126. 10.1186/1471-2334-9-126, 2739209, 19671147.
-
(2009)
BMC Infect Dis
, vol.9
, pp. 126
-
-
Dierkes, C.1
Ehrenstein, B.2
Siebig, S.3
Linde, H.J.4
Reischl, U.5
Salzberger, B.6
-
31
-
-
84871867383
-
Cost analysis of real-time polymerase chain reaction microbiological diagnosis in patients with septic shock
-
Alvarez J, Mar J, Varela-Ledo E, Garea M, Matinez-Lamas L, Rodriguez J, Regueiro B. Cost analysis of real-time polymerase chain reaction microbiological diagnosis in patients with septic shock. Anaesth Intensive Care 2012, 40(6):958-963.
-
(2012)
Anaesth Intensive Care
, vol.40
, Issue.6
, pp. 958-963
-
-
Alvarez, J.1
Mar, J.2
Varela-Ledo, E.3
Garea, M.4
Matinez-Lamas, L.5
Rodriguez, J.6
Regueiro, B.7
-
32
-
-
77957897126
-
Cost and mortality prediction using polymerase chain reaction pathogen detection in sepsis: evidence from three observational trials
-
10.1186/cc9294, 3219292, 20950442
-
Lehmann LE, Herpichboehm B, Kost GJ, Kollef MH, Stuber F. Cost and mortality prediction using polymerase chain reaction pathogen detection in sepsis: evidence from three observational trials. Crit Care 2010, 14(5):R186. 10.1186/cc9294, 3219292, 20950442.
-
(2010)
Crit Care
, vol.14
, Issue.5
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Lehmann, L.E.1
Herpichboehm, B.2
Kost, G.J.3
Kollef, M.H.4
Stuber, F.5
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