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Volumn 118, Issue 1, 2000, Pages 146-155

The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting

Author keywords

Antibiotics; Bacteremia; Bloodstream infections; Candida species; Enterococci; Intensive care; Outcomes; Resistance; Staphylococcus aureus

Indexed keywords

ANTIBIOTIC AGENT; VANCOMYCIN;

EID: 0141610906     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.118.1.146     Document Type: Article
Times cited : (1600)

References (48)
  • 1
    • 0032577584 scopus 로고    scopus 로고
    • Clinical implications of nosocomial Gram-positive bacteremia and superimposed antimicrobial resistance
    • Linden PK. Clinical implications of nosocomial Gram-positive bacteremia and superimposed antimicrobial resistance. Am J Med 1998; 104:24S-33S
    • (1998) Am J Med , vol.104 , pp. 24S-33S
    • Linden, P.K.1
  • 2
    • 0031762306 scopus 로고    scopus 로고
    • The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection
    • Leibovici L, Shraga I, Drucker M, et al. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med 1998; 244:379-386
    • (1998) J Intern Med , vol.244 , pp. 379-386
    • Leibovici, L.1    Shraga, I.2    Drucker, M.3
  • 3
    • 19244362627 scopus 로고    scopus 로고
    • Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli bloodstream infection: A case-control and molecular epidemiologic investigation
    • Schiappa DA, Hayden MK, Matushek MG, et al. Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli bloodstream infection: A case-control and molecular epidemiologic investigation. J Infect Dis 1996; 174:529-536
    • (1996) J Infect Dis , vol.174 , pp. 529-536
    • Schiappa, D.A.1    Hayden, M.K.2    Matushek, M.G.3
  • 4
    • 0030945048 scopus 로고    scopus 로고
    • The clinical significance of positive blood cultures in the 1990s: A prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults
    • Weinstein MP, Towns ML, Quartey SM, et al. The clinical significance of positive blood cultures in the 1990s: A prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. Clin Infect Dis 1997; 24:584-602
    • (1997) Clin Infect Dis , vol.24 , pp. 584-602
    • Weinstein, M.P.1    Towns, M.L.2    Quartey, S.M.3
  • 5
    • 0029909181 scopus 로고    scopus 로고
    • Epidemiology and outcome of Pseudomonas aeruginosa bacteremia, with special emphasis on the influence of antibiotic treatment: Analysis of 189 episodes
    • Vidal F, Mensa J, Almela M, et al. Epidemiology and outcome of Pseudomonas aeruginosa bacteremia, with special emphasis on the influence of antibiotic treatment: Analysis of 189 episodes. Arch Intern Med 1996; 156:2121-2126
    • (1996) Arch Intern Med , vol.156 , pp. 2121-2126
    • Vidal, F.1    Mensa, J.2    Almela, M.3
  • 6
    • 17144437650 scopus 로고    scopus 로고
    • Comparative study of bacteremias caused by Enterococcus spp. With and without high-level resistance to gentamicin
    • Caballero-Granado FJ, Cisneros JM, Luque R, et al. Comparative study of bacteremias caused by Enterococcus spp. with and without high-level resistance to gentamicin. J Clin Microbiol 1998; 36:520-525
    • (1998) J Clin Microbiol , vol.36 , pp. 520-525
    • Caballero-Granado, F.J.1    Cisneros, J.M.2    Luque, R.3
  • 7
    • 0020791999 scopus 로고
    • Analysis of 1186 episodes of Gram-negative bacteremia in non-university hospitals: The effects of antimicrobial therapy
    • Bryan CS, Reynolds KL, Brenner ER. Analysis of 1186 episodes of Gram-negative bacteremia in non-university hospitals: the effects of antimicrobial therapy. Rev Infect Dis 1983; 5:629-638
    • (1983) Rev Infect Dis , vol.5 , pp. 629-638
    • Bryan, C.S.1    Reynolds, K.L.2    Brenner, E.R.3
  • 8
    • 0025938759 scopus 로고
    • Enterobacter bacteremia: Clinical features and emergence of antibiotic resistance during therapy
    • Chow JW, Fine MJ, Shlaes DM, et al. Enterobacter bacteremia: Clinical features and emergence of antibiotic resistance during therapy. Ann Intern Med 1991; 115:585-590
    • (1991) Ann Intern Med , vol.115 , pp. 585-590
    • Chow, J.W.1    Fine, M.J.2    Shlaes, D.M.3
  • 9
    • 0031032132 scopus 로고    scopus 로고
    • Enterococcal bacteremia in the surgical intensive care unit: Does vancomycin resistance affect mortality?
    • Mainous MR, Lipsett PA, O'Brien M. Enterococcal bacteremia in the surgical intensive care unit: Does vancomycin resistance affect mortality? Arch Surg 1997; 132:76-81
    • (1997) Arch Surg , vol.132 , pp. 76-81
    • Mainous, M.R.1    Lipsett, P.A.2    O'Brien, M.3
  • 10
    • 0031925669 scopus 로고    scopus 로고
    • Vancomycin-resistant and vancomycin-susceptible enterococcal bacteremia: Comparison of clinical features and outcomes
    • Lucas GM, Lechtzin N, Puryear DW, et al. Vancomycin-resistant and vancomycin-susceptible enterococcal bacteremia: Comparison of clinical features and outcomes. Clin Infect Dis 1998; 26:1127-1133
    • (1998) Clin Infect Dis , vol.26 , pp. 1127-1133
    • Lucas, G.M.1    Lechtzin, N.2    Puryear, D.W.3
  • 11
    • 0029830679 scopus 로고    scopus 로고
    • Nosocomial and community-acquired Staphylococcus aureus bacteremias from 1980 to 1993: Impact of intravascular devices and methicillin resistance
    • Steinberg JP, Clark CC, Hackman BO. Nosocomial and community-acquired Staphylococcus aureus bacteremias from 1980 to 1993: Impact of intravascular devices and methicillin resistance. Clin Infect Dis 1996; 23:255-259
    • (1996) Clin Infect Dis , vol.23 , pp. 255-259
    • Steinberg, J.P.1    Clark, C.C.2    Hackman, B.O.3
  • 12
    • 0032911760 scopus 로고    scopus 로고
    • Inadequate antimicrobial treatment of infections: A risk factor for hospital mortality among critically ill patients
    • Kollef MH, Sherman G, Ward S, et al. Inadequate antimicrobial treatment of infections: A risk factor for hospital mortality among critically ill patients. Chest 1999; 115:462-474
    • (1999) Chest , vol.115 , pp. 462-474
    • Kollef, M.H.1    Sherman, G.2    Ward, S.3
  • 13
    • 0031012189 scopus 로고    scopus 로고
    • Consequences of bacterial resistance to antibiotics in medical practice
    • Ascar JF. Consequences of bacterial resistance to antibiotics in medical practice. Clin Infect Dis 1997; 24:S17-S18
    • (1997) Clin Infect Dis , vol.24 , pp. S17-S18
    • Ascar, J.F.1
  • 14
    • 0026705492 scopus 로고
    • Epidemiology of drug resistance: Implications for a post-antimicrobial era
    • Cohen ML. Epidemiology of drug resistance: Implications for a post-antimicrobial era. Science 1992; 257:1050-1055
    • (1992) Science , vol.257 , pp. 1050-1055
    • Cohen, M.L.1
  • 16
    • 0033051132 scopus 로고    scopus 로고
    • The economic impact of Staphylococcus aureus infection in New York City hospitals
    • Rubin RJ, Harrington CA, Poon A, et al. The economic impact of Staphylococcus aureus infection in New York City hospitals. Emerg Infect Dis 1999; 5:9-17
    • (1999) Emerg Infect Dis , vol.5 , pp. 9-17
    • Rubin, R.J.1    Harrington, C.A.2    Poon, A.3
  • 17
    • 0033599982 scopus 로고    scopus 로고
    • Health and economic outcomes of antibiotic resistance in Pseudomonas aeruginosa
    • Carmeli Y, Troillet N, Karchmer AW, et al. Health and economic outcomes of antibiotic resistance in Pseudomonas aeruginosa. Arch Intern Med 1999; 159:1127-1132
    • (1999) Arch Intern Med , vol.159 , pp. 1127-1132
    • Carmeli, Y.1    Troillet, N.2    Karchmer, A.W.3
  • 18
    • 0023446047 scopus 로고
    • Health and economic impact of antimicrobial resistance
    • Holemberg SD, Solomon SL, Blake PA. Health and economic impact of antimicrobial resistance. Rev Infect Dis 1987; 9:1065-1078
    • (1987) Rev Infect Dis , vol.9 , pp. 1065-1078
    • Holemberg, S.D.1    Solomon, S.L.2    Blake, P.A.3
  • 19
    • 0024614038 scopus 로고
    • Bug-drug resistance: Sometimes less is more
    • Phelps CE. Bug-drug resistance: Sometimes less is more. Med Care 1989; 27:194-203
    • (1989) Med Care , vol.27 , pp. 194-203
    • Phelps, C.E.1
  • 20
    • 0031708359 scopus 로고    scopus 로고
    • Pneumonia caused by penicillin-non-susceptible and penicillin-susceptible pneumococci in adults: A case-control study
    • Einarsson S, Kristjansson M, Kristinsson KG, et al. Pneumonia caused by penicillin-non-susceptible and penicillin-susceptible pneumococci in adults: A case-control study. Scand J Infect Dis 1998; 30:253-256
    • (1998) Scand J Infect Dis , vol.30 , pp. 253-256
    • Einarsson, S.1    Kristjansson, M.2    Kristinsson, K.G.3
  • 21
    • 0033582163 scopus 로고    scopus 로고
    • A novel antimicrobial agent joins the battle against resistant bacteria
    • Moellering RC. A novel antimicrobial agent joins the battle against resistant bacteria. Ann Intern Med 1999; 130:155-157
    • (1999) Ann Intern Med , vol.130 , pp. 155-157
    • Moellering, R.C.1
  • 22
    • 0031021241 scopus 로고    scopus 로고
    • The role of fundamental research and biotechnology in finding solutions to the global problem of antibiotic resistance
    • Hancock RE. The role of fundamental research and biotechnology in finding solutions to the global problem of antibiotic resistance. Clin Infect Dis 1997; 24:S148-S150
    • (1997) Clin Infect Dis , vol.24 , pp. S148-S150
    • Hancock, R.E.1
  • 23
    • 0031012190 scopus 로고    scopus 로고
    • Antibiotic resistance: A view from the pharmaceutical industry
    • Bax RP. Antibiotic resistance: A view from the pharmaceutical industry. Clin Infect Dis 1997; 24:S151-S153
    • (1997) Clin Infect Dis , vol.24 , pp. S151-S153
    • Bax, R.P.1
  • 24
    • 0030221479 scopus 로고    scopus 로고
    • The emergent needs for basic research, education, and surveillance of antimicrobial resistance: Problems facing the report from the American Society for Microbiology Task Force on Antibiotic Resistance
    • Jones RN. The emergent needs for basic research, education, and surveillance of antimicrobial resistance: Problems facing the report from the American Society for Microbiology Task Force on Antibiotic Resistance. Diag Microbiol Infect Dis 1996; 25:153-161
    • (1996) Diag Microbiol Infect Dis , vol.25 , pp. 153-161
    • Jones, R.N.1
  • 25
    • 0026409568 scopus 로고
    • The APACHE III prognostic system: Risk prediction of hospital mortality for critically ill hospitalized adults
    • Knaus WA, Wagner DP, Draper EA, et al. The APACHE III prognostic system: Risk prediction of hospital mortality for critically ill hospitalized adults. Chest 1991; 100:1619-1636
    • (1991) Chest , vol.100 , pp. 1619-1636
    • Knaus, W.A.1    Wagner, D.P.2    Draper, E.A.3
  • 26
    • 0026955324 scopus 로고
    • Patient selection for clinical investigation of ventilator-associated pneumonia: Criteria for evaluating diagnostic techniques
    • Pingleton SK, Fagon JY, Leeper KV Jr. Patient selection for clinical investigation of ventilator-associated pneumonia: Criteria for evaluating diagnostic techniques. Chest 1992; 102: 553S-556S
    • (1992) Chest , vol.102 , pp. 553S-556S
    • Pingleton, S.K.1    Fagon, J.Y.2    Leeper, K.V.3
  • 28
    • 0027382380 scopus 로고
    • Ventilator-associated pneumonia: A multivariate analysis
    • Kollef MH. Ventilator-associated pneumonia: A multivariate analysis. JAMA 1993; 270:1965-1970
    • (1993) JAMA , vol.270 , pp. 1965-1970
    • Kollef, M.H.1
  • 29
    • 0025128163 scopus 로고
    • Elevated von Willebrand factor antigen is an early phase predictor of acute lung injury in nonpulmonary sepsis syndrome
    • Rubin DB, Wiener-Kronish JP, Murray JF, et al. Elevated von Willebrand factor antigen is an early phase predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest 1990; 86:474-480
    • (1990) J Clin Invest , vol.86 , pp. 474-480
    • Rubin, D.B.1    Wiener-Kronish, J.P.2    Murray, J.F.3
  • 30
    • 0026710191 scopus 로고
    • Definitions for sepsis and multiple organ failure and guidelines for the use of innovative therapies in sepsis
    • American College of Chest Physicians/Society of Critical Care Med Consensus Conference. Definitions for sepsis and multiple organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101:1644-1655
    • (1992) Chest , vol.101 , pp. 1644-1655
  • 32
    • 0001741987 scopus 로고
    • Cary, NC: SAS Institute
    • SAS/STAT User's Guide (vol 2). Cary, NC: SAS Institute, 1990; 1071-1126
    • (1990) Sas/stat User's Guide , vol.2 , pp. 1071-1126
  • 33
    • 0027534004 scopus 로고
    • The risk of determining risk with multivariable models
    • Concato J, Feinstein AR, Holford TR. The risk of determining risk with multivariable models. Ann Intern Med 1993; 118:201-210
    • (1993) Ann Intern Med , vol.118 , pp. 201-210
    • Concato, J.1    Feinstein, A.R.2    Holford, T.R.3
  • 34
    • 0000230616 scopus 로고
    • Analysis of crude data
    • Rothman K, ed. Boston, MA: Little Brown
    • Rothman KJ. Analysis of crude data. In: Rothman K, ed. Modern epidemiology. Boston, MA: Little Brown, 1986; 153-174
    • (1986) Modern Epidemiology , pp. 153-174
    • Rothman, K.J.1
  • 35
    • 0031936787 scopus 로고    scopus 로고
    • The influence of mini-BAL cultures on patient outcomes: Implications for the antibiotic management of ventilator-associated pneumonia
    • Kollef MH, Ward S. The influence of mini-BAL cultures on patient outcomes: Implications for the antibiotic management of ventilator-associated pneumonia. Chest 1998; 113:412-420
    • (1998) Chest , vol.113 , pp. 412-420
    • Kollef, M.H.1    Ward, S.2
  • 36
    • 0030901413 scopus 로고    scopus 로고
    • Impact of BAL data on the therapy and outcome of ventilator-associated pneumonia
    • Luna CM, Vujacich P, Niederman MS, et al. Impact of BAL data on the therapy and outcome of ventilator-associated pneumonia. Chest 1997; 111:676-685
    • (1997) Chest , vol.111 , pp. 676-685
    • Luna, C.M.1    Vujacich, P.2    Niederman, M.S.3
  • 37
    • 9344239309 scopus 로고    scopus 로고
    • Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit
    • Alvarez-Lerma F. Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit: ICU-Acquired Pneumonia Study Group. Intensive Care Med 1996; 22:387-394
    • (1996) Intensive Care Med , vol.22 , pp. 387-394
    • Alvarez-Lerma, F.1
  • 38
    • 0030788929 scopus 로고    scopus 로고
    • The value of routine microbial investigation in ventilator-associated pneumonia
    • Rello J, Gallego M, Mariscal D, et al. The value of routine microbial investigation in ventilator-associated pneumonia. Am J Respir Crit Care Med 1997; 156:196-200
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 196-200
    • Rello, J.1    Gallego, M.2    Mariscal, D.3
  • 39
    • 0033023730 scopus 로고    scopus 로고
    • Nosocomial infections in medical intensive care units in the United States: National Nosocomial Infections Surveillance System
    • Richards MJ, Edwards JR, Culver DH, et al. Nosocomial infections in medical intensive care units in the United States: National Nosocomial Infections Surveillance System. Crit Care Med 1999; 27:887-892
    • (1999) Crit Care Med , vol.27 , pp. 887-892
    • Richards, M.J.1    Edwards, J.R.2    Culver, D.H.3
  • 40
    • 0032415565 scopus 로고    scopus 로고
    • Resistance of artificial biofilms of Pseudomonas aeruginosa to imipenem and tobramycin
    • Coquet L, Junter GA, Jouenne T. Resistance of artificial biofilms of Pseudomonas aeruginosa to imipenem and tobramycin. J Antimicrob Chemother 1998; 42:755-760
    • (1998) J Antimicrob Chemother , vol.42 , pp. 755-760
    • Coquet, L.1    Junter, G.A.2    Jouenne, T.3
  • 41
    • 0031886820 scopus 로고    scopus 로고
    • Ventilator-associated pneumonia caused by potentially drug-resistant bacteria
    • Trouillet JL, Chastre J, Vuagnat A, et al. Ventilator-associated pneumonia caused by potentially drug-resistant bacteria. Am J Respir Crit Care Med 1998; 157:531-539
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 531-539
    • Trouillet, J.L.1    Chastre, J.2    Vuagnat, A.3
  • 42
    • 0031974518 scopus 로고    scopus 로고
    • Predictors of mortality in patients with bacteremia: The importance of functional status
    • Deulofeu F, Cervello B, Capell S, et al. Predictors of mortality in patients with bacteremia: The importance of functional status. J Am Geriat Soc 1998; 46:14-18
    • (1998) J Am Geriat Soc , vol.46 , pp. 14-18
    • Deulofeu, F.1    Cervello, B.2    Capell, S.3
  • 43
    • 0030970810 scopus 로고    scopus 로고
    • Monotherapy versus beta-lactam-aminoglycoside combination treatment for Gramnegative bacteremia: A prospective, observational study
    • Leibovici L, Paul M, Poznanski O, et al. Monotherapy versus beta-lactam-aminoglycoside combination treatment for Gramnegative bacteremia: A prospective, observational study. Antimicrob Agents Chemother 1997; 41:1127-1133
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1127-1133
    • Leibovici, L.1    Paul, M.2    Poznanski, O.3
  • 44
    • 0032779611 scopus 로고    scopus 로고
    • Variations in etiology of ventilator-associated pneumonia across four treatment sites: Implications for antimicrobial prescribing practices
    • Rello J, Sa-Borges M, Correa H, et al. Variations in etiology of ventilator-associated pneumonia across four treatment sites: Implications for antimicrobial prescribing practices. Am J Respir Crit Care Med 1999; 160:608-613
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 608-613
    • Rello, J.1    Sa-Borges, M.2    Correa, H.3
  • 45
    • 0028353408 scopus 로고
    • Improving empiric antibiotic selection using computer decision support
    • Evans RS, Classen DC, Pestotnik SL, et al. Improving empiric antibiotic selection using computer decision support. Arch Intern Med 1994; 154:878-884
    • (1994) Arch Intern Med , vol.154 , pp. 878-884
    • Evans, R.S.1    Classen, D.C.2    Pestotnik, S.L.3
  • 46
    • 0032556943 scopus 로고    scopus 로고
    • A computerassisted management program for antibiotics and other anti-infective agents
    • Evans RS, Pestotnik SL, Classen DC, et al. A computerassisted management program for antibiotics and other anti-infective agents. N Engl J Med 1998; 338:232-238
    • (1998) N Engl J Med , vol.338 , pp. 232-238
    • Evans, R.S.1    Pestotnik, S.L.2    Classen, D.C.3
  • 47
    • 0030874060 scopus 로고    scopus 로고
    • Scheduled rotation of antibiotic classes: A strategy to decrease the incidence of ventilator-associated pneumonia due to antibiotic-resistant Gram-negative bacteria
    • Kollef MH, Vlasnik J, Sharpless L, et al. Scheduled rotation of antibiotic classes: A strategy to decrease the incidence of ventilator-associated pneumonia due to antibiotic-resistant Gram-negative bacteria. Am J Respir Crit Care Med 1997; 156:1040-1048
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 1040-1048
    • Kollef, M.H.1    Vlasnik, J.2    Sharpless, L.3
  • 48
    • 0033825695 scopus 로고    scopus 로고
    • Rotation and restricted use of antibiotics in a medical intensive care unit: Impact on the incidence of ventilator-associated pneumonia caused by antibiotic-resistant Gram-negative bacteria
    • in press
    • Gruson D, Hilbert G, Vargas F, et al. Rotation and restricted use of antibiotics in a medical intensive care unit: Impact on the incidence of ventilator-associated pneumonia caused by antibiotic-resistant Gram-negative bacteria. Am J Respir Crit Care Med 2000 (in press)
    • (2000) Am J Respir Crit Care Med
    • Gruson, D.1    Hilbert, G.2    Vargas, F.3


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