메뉴 건너뛰기




Volumn 50, Issue 5, 2014, Pages 457-467

Gemcitabine chemotherapy induces phenotypic alterations of tumor cells that facilitate antitumor T cell responses in a mouse model of oral cancer

Author keywords

Antitumor immune response; Chemotherapy; Gemcitabine; Oral cancer

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GEMCITABINE; INTERCELLULAR ADHESION MOLECULE 1; LIPOCORTIN 5; PADGEM PROTEIN; SODIUM CHLORIDE; VASCULAR CELL ADHESION MOLECULE 1; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE;

EID: 84899122784     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2014.01.013     Document Type: Article
Times cited : (19)

References (43)
  • 3
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • J. Galon, A. Costes, F. Sanchez-Cabo, A. Kirilovsky, B. Mlecnik, and C. Lagorce-Pagès et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome Science 313 5795 2006 1960 1964
    • (2006) Science , vol.313 , Issue.5795 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pagès, C.6
  • 4
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • W. Zou Immunosuppressive networks in the tumour environment and their therapeutic relevance Nat Rev Cancer 5 4 2005 263 274
    • (2005) Nat Rev Cancer , vol.5 , Issue.4 , pp. 263-274
    • Zou, W.1
  • 7
    • 31544448260 scopus 로고    scopus 로고
    • Cranking the immunologic engine with chemotherapy: Using context to drive tumor antigen cross-presentation towards useful antitumor immunity
    • R.G. van der Most, A. Currie, B.W. Robinson, and R.A. Lake Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity Cancer Res 66 2 2006 601 604
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 601-604
    • Van Der Most, R.G.1    Currie, A.2    Robinson, B.W.3    Lake, R.A.4
  • 8
    • 48149096721 scopus 로고    scopus 로고
    • Combined modality immunotherapy and chemotherapy: A new perspective
    • R. Ramakrishnan, S. Antonia, and D.I. Gabrilovich Combined modality immunotherapy and chemotherapy: a new perspective Cancer Immunol Immunother 57 10 2008 1523 1529
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.10 , pp. 1523-1529
    • Ramakrishnan, R.1    Antonia, S.2    Gabrilovich, D.I.3
  • 9
    • 29144512401 scopus 로고    scopus 로고
    • Concurrent cisplatin/gemcitabine chemotherapy along with radiotherapy in locally advanced cervical carcinoma: A phase II trial
    • J. Umanzor, M. Aguiluz, C. Pineda, S. Andrade, M. Erazo, and C. Flores et al. Concurrent cisplatin/gemcitabine chemotherapy along with radiotherapy in locally advanced cervical carcinoma: a phase II trial Gynecol Oncol 100 1 2006 70 75
    • (2006) Gynecol Oncol , vol.100 , Issue.1 , pp. 70-75
    • Umanzor, J.1    Aguiluz, M.2    Pineda, C.3    Andrade, S.4    Erazo, M.5    Flores, C.6
  • 10
    • 43049183349 scopus 로고    scopus 로고
    • Gemcitabine in the treatment of metastatic pancreatic cancer
    • A. Hilbig, and H. Oettle Gemcitabine in the treatment of metastatic pancreatic cancer Expert Rev Anticancer Ther 8 4 2008 511 523
    • (2008) Expert Rev Anticancer Ther , vol.8 , Issue.4 , pp. 511-523
    • Hilbig, A.1    Oettle, H.2
  • 11
    • 77955914277 scopus 로고    scopus 로고
    • Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205
    • P.A. Philip, J. Benedetti, C.L. Corless, R. Wong, E.M. O'Reilly, and P.J. Flynn et al. Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205 J Clin Oncol 28 22 2010 3605 3610
    • (2010) J Clin Oncol , vol.28 , Issue.22 , pp. 3605-3610
    • Philip, P.A.1    Benedetti, J.2    Corless, C.L.3    Wong, R.4    O'Reilly, E.M.5    Flynn, P.J.6
  • 12
    • 79959988955 scopus 로고    scopus 로고
    • Gemcitabine chemotherapy for the treatment of metastatic bladder carcinoma
    • M.D. Shelley, A. Cleves, T.J. Wilt, and M.D. Mason Gemcitabine chemotherapy for the treatment of metastatic bladder carcinoma BJU Int 108 2 2011 168 179
    • (2011) BJU Int , vol.108 , Issue.2 , pp. 168-179
    • Shelley, M.D.1    Cleves, A.2    Wilt, T.J.3    Mason, M.D.4
  • 13
    • 0037089545 scopus 로고    scopus 로고
    • Gemcitabine exerts a selective effect on the humoral immune response: Implications for combination chemo-immunotherapy
    • A.K. Nowak, B.W. Robinson, and R.A. Lake Gemcitabine exerts a selective effect on the humoral immune response: implications for combination chemo-immunotherapy Cancer Res 62 8 2002 2353 2358
    • (2002) Cancer Res , vol.62 , Issue.8 , pp. 2353-2358
    • Nowak, A.K.1    Robinson, B.W.2    Lake, R.A.3
  • 14
    • 0042591416 scopus 로고    scopus 로고
    • Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors
    • A.K. Nowak, B.W. Robinson, and R.A. Lake Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors Cancer Res 63 15 2003 4490 4496
    • (2003) Cancer Res , vol.63 , Issue.15 , pp. 4490-4496
    • Nowak, A.K.1    Robinson, B.W.2    Lake, R.A.3
  • 15
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • E. Suzuki, V. Kapoor, A.S. Jassar, L.R. Kaiser, and S.M. Albelda Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity Clin Cancer Res 11 18 2005 6713 6721
    • (2005) Clin Cancer Res , vol.11 , Issue.18 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 16
    • 34547630506 scopus 로고    scopus 로고
    • A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model
    • H.J. Ko, Y.J. Kim, Y.S. Kim, W.S. Chang, S.Y. Ko, and S.Y. Chang et al. A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model Cancer Res 67 15 2007 7477 7486
    • (2007) Cancer Res , vol.67 , Issue.15 , pp. 7477-7486
    • Ko, H.J.1    Kim, Y.J.2    Kim, Y.S.3    Chang, W.S.4    Ko, S.Y.5    Chang, S.Y.6
  • 17
    • 0038326676 scopus 로고    scopus 로고
    • Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells
    • A.K. Nowak, R.A. Lake, A.L. Marzo, B. Scott, W.R. Heath, and E.J. Collins et al. Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells J Immunol 170 10 2003 4905 4913
    • (2003) J Immunol , vol.170 , Issue.10 , pp. 4905-4913
    • Nowak, A.K.1    Lake, R.A.2    Marzo, A.L.3    Scott, B.4    Heath, W.R.5    Collins, E.J.6
  • 18
    • 10744232091 scopus 로고    scopus 로고
    • Phase i study of gemcitabine given weekly as a short infusion for non-small cell lung cancer: Results and possible immune system-related mechanisms
    • M.L. Levitt, B. Kassem, W.E. Gooding, L.M. Miketic, R.J. Landreneau, and P.F. Ferson et al. Phase I study of gemcitabine given weekly as a short infusion for non-small cell lung cancer: results and possible immune system-related mechanisms Lung Cancer 43 3 2004 335 344
    • (2004) Lung Cancer , vol.43 , Issue.3 , pp. 335-344
    • Levitt, M.L.1    Kassem, B.2    Gooding, W.E.3    Miketic, L.M.4    Landreneau, R.J.5    Ferson, P.F.6
  • 19
    • 22244489353 scopus 로고    scopus 로고
    • Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas
    • J.M. Plate, A.E. Plate, S. Shott, S. Bograd, and J.E. Harris Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas Cancer Immunol Immunother 54 9 2005 915 925
    • (2005) Cancer Immunol Immunother , vol.54 , Issue.9 , pp. 915-925
    • Plate, J.M.1    Plate, A.E.2    Shott, S.3    Bograd, S.4    Harris, J.E.5
  • 20
    • 33644789357 scopus 로고    scopus 로고
    • Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients
    • P. Correale, M.G. Cusi, K.Y. Tsang, M.T. Del Vecchio, S. Marsili, and M.L. Placa et al. Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients J Clin Oncol 23 35 2005 8950 8958
    • (2005) J Clin Oncol , vol.23 , Issue.35 , pp. 8950-8958
    • Correale, P.1    Cusi, M.G.2    Tsang, K.Y.3    Del Vecchio, M.T.4    Marsili, S.5    Placa, M.L.6
  • 21
    • 24944478531 scopus 로고    scopus 로고
    • Leveraging the activity of tumor vaccines with cytotoxic chemotherapy
    • L.A. Emens, and E.M. Jaffee Leveraging the activity of tumor vaccines with cytotoxic chemotherapy Cancer Res 65 18 2005 8059 8064
    • (2005) Cancer Res , vol.65 , Issue.18 , pp. 8059-8064
    • Emens, L.A.1    Jaffee, E.M.2
  • 22
    • 77957992952 scopus 로고    scopus 로고
    • Chemoimmunotherapy
    • L.A. Emens Chemoimmunotherapy Cancer J 16 4 2010 295 303
    • (2010) Cancer J , vol.16 , Issue.4 , pp. 295-303
    • Emens, L.A.1
  • 23
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • J.P. Machiels, R.T. Reilly, L.A. Emens, A.M. Ercolini, R.Y. Lei, and D. Weintraub et al. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice Cancer Res 61 9 2001 3689 3697
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3689-3697
    • Machiels, J.P.1    Reilly, R.T.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5    Weintraub, D.6
  • 24
    • 0344924989 scopus 로고    scopus 로고
    • Cisplatin augments cytotoxic T-lymphocyte-mediated antitumor immunity in poorly immunogenic murine lung cancer
    • R.E. Merritt, A. Mahtabifard, R.E. Yamada, R.G. Crystal, and R.J. Korst Cisplatin augments cytotoxic T-lymphocyte-mediated antitumor immunity in poorly immunogenic murine lung cancer J Thorac Cardiovasc Surg 126 5 2003 1609 1617
    • (2003) J Thorac Cardiovasc Surg , vol.126 , Issue.5 , pp. 1609-1617
    • Merritt, R.E.1    Mahtabifard, A.2    Yamada, R.E.3    Crystal, R.G.4    Korst, R.J.5
  • 25
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • D.I. Gabrilovich, and S. Nagaraj Myeloid-derived suppressor cells as regulators of the immune system Nat Rev Immunol 9 3 2009 162 174
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 26
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • P. Sinha, V.K. Clements, S.K. Bunt, S.M. Albelda, and S. Ostrand-Rosenberg Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response J Immunol 179 2 2007 977 983
    • (2007) J Immunol , vol.179 , Issue.2 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 27
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • C. Murdoch, M. Muthana, S.B. Coffelt, and C.E. Lewis The role of myeloid cells in the promotion of tumour angiogenesis Nat Rev Cancer 8 8 2008 618 631
    • (2008) Nat Rev Cancer , vol.8 , Issue.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 28
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • J.I. Youn, S. Nagaraj, M. Collazo, and D.I. Gabrilovich Subsets of myeloid-derived suppressor cells in tumor-bearing mice J Immunol 181 8 2008 5791 5802
    • (2008) J Immunol , vol.181 , Issue.8 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 29
    • 77951086882 scopus 로고    scopus 로고
    • 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • J. Vincent, G. Mignot, F. Chalmin, S. Ladoire, M. Bruchard, and A. Chevriaux et al. 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity Cancer Res 70 8 2010 3052 3061
    • (2010) Cancer Res , vol.70 , Issue.8 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.5    Chevriaux, A.6
  • 30
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • W. Zou Regulatory T cells, tumour immunity and immunotherapy Nat Rev Immunol 6 4 2006 295 307
    • (2006) Nat Rev Immunol , vol.6 , Issue.4 , pp. 295-307
    • Zou, W.1
  • 31
    • 70449360735 scopus 로고    scopus 로고
    • Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma
    • A. Bonertz, J. Weitz, D.H. Pietsch, N.N. Rahbari, C. Schlude, and Y. Ge et al. Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma J Clin Invest 119 11 2009 3311 3321
    • (2009) J Clin Invest , vol.119 , Issue.11 , pp. 3311-3321
    • Bonertz, A.1    Weitz, J.2    Pietsch, D.H.3    Rahbari, N.N.4    Schlude, C.5    Ge, Y.6
  • 32
    • 35948952840 scopus 로고    scopus 로고
    • The frequency and suppressor function of CD4+ CD25 high Foxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck
    • L. Strauss, C. Bergmann, W. Gooding, J.T. Johnson, and T.L. Whiteside The frequency and suppressor function of CD4+ CD25 high Foxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck Clin Cancer Res 13 21 2007 6301 6311
    • (2007) Clin Cancer Res , vol.13 , Issue.21 , pp. 6301-6311
    • Strauss, L.1    Bergmann, C.2    Gooding, W.3    Johnson, J.T.4    Whiteside, T.L.5
  • 33
    • 33750807427 scopus 로고    scopus 로고
    • CD4+ CD25 high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
    • A.M. Miller, K. Lundberg, V. Ozenci, A.H. Banham, M. Hellström, and L. Egevad et al. CD4+ CD25 high T cells are enriched in the tumor and peripheral blood of prostate cancer patients J Immunol 177 10 2006 7398 7405
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 7398-7405
    • Miller, A.M.1    Lundberg, K.2    Ozenci, V.3    Banham, A.H.4    Hellström, M.5    Egevad, L.6
  • 34
    • 1642378018 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
    • F. Ghiringhelli, N. Larmonier, E. Schmitt, A. Parcellier, D. Cathelin, and C. Garrido et al. CD4+ CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative Eur J Immunol 34 2 2004 336 344
    • (2004) Eur J Immunol , vol.34 , Issue.2 , pp. 336-344
    • Ghiringhelli, F.1    Larmonier, N.2    Schmitt, E.3    Parcellier, A.4    Cathelin, D.5    Garrido, C.6
  • 35
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • M.E. Lutsiak, R.T. Semnani, R. De Pascalis, S.V. Kashmiri, J. Schlom, and H. Sabzevari Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide Blood 105 7 2005 2862 2868
    • (2005) Blood , vol.105 , Issue.7 , pp. 2862-2868
    • Lutsiak, M.E.1    Semnani, R.T.2    De Pascalis, R.3    Kashmiri, S.V.4    Schlom, J.5    Sabzevari, H.6
  • 36
    • 0032945057 scopus 로고    scopus 로고
    • Synergistic induction of ICAM-1 expression by cisplatin and 5-fluorouracil in a cancer cell line via a NF-kappaB independent pathway
    • K. Takizawa, R. Kamijo, D. Ito, M. Hatori, K. Sumitani, and M. Nagumo Synergistic induction of ICAM-1 expression by cisplatin and 5-fluorouracil in a cancer cell line via a NF-kappaB independent pathway Br J Cancer 80 7 1999 954 963
    • (1999) Br J Cancer , vol.80 , Issue.7 , pp. 954-963
    • Takizawa, K.1    Kamijo, R.2    Ito, D.3    Hatori, M.4    Sumitani, K.5    Nagumo, M.6
  • 37
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • S. Gasser, S. Orsulic, E.J. Brown, and D.H. Raulet The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor Nature 436 7054 2005 1186 1190
    • (2005) Nature , vol.436 , Issue.7054 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 38
    • 22244485707 scopus 로고    scopus 로고
    • Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate
    • S. Armeanu, M. Bitzer, U.M. Lauer, S. Venturelli, A. Pathil, and M. Krusch et al. Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate Cancer Res 65 14 2005 6321 6329
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6321-6329
    • Armeanu, S.1    Bitzer, M.2    Lauer, U.M.3    Venturelli, S.4    Pathil, A.5    Krusch, M.6
  • 39
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class i expression, and induces successful antitumor immunotherapy
    • E.A. Reits, J.W. Hodge, C.A. Herberts, T.A. Groothuis, M. Chakraborty, and E.K. Wansley et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy J Exp Med 203 5 2006 1259 1271
    • (2006) J Exp Med , vol.203 , Issue.5 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3    Groothuis, T.A.4    Chakraborty, M.5    Wansley, E.K.6
  • 40
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • A. Ashkenazi, and V.M. Dixit Death receptors: signaling and modulation Science 281 5381 1998 1305 1308
    • (1998) Science , vol.281 , Issue.5381 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 41
    • 0030966954 scopus 로고    scopus 로고
    • Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity
    • O. Micheau, E. Solary, A. Hammann, F. Martin, and M.T. Dimanche-Boitrel Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity J Natl Cancer Inst 89 11 1997 783 789
    • (1997) J Natl Cancer Inst , vol.89 , Issue.11 , pp. 783-789
    • Micheau, O.1    Solary, E.2    Hammann, A.3    Martin, F.4    Dimanche-Boitrel, M.T.5
  • 42
    • 0042121068 scopus 로고    scopus 로고
    • Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines
    • C.M. van Geelen, E.G. de Vries, T.K. Le, R.P. van Weeghel, and S. de Jong Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines Br J Cancer 89 2 2003 363 373
    • (2003) Br J Cancer , vol.89 , Issue.2 , pp. 363-373
    • Van Geelen, C.M.1    De Vries, E.G.2    Le, T.K.3    Van Weeghel, R.P.4    De Jong, S.5
  • 43
    • 41849127108 scopus 로고    scopus 로고
    • Paclitaxel (Taxol)-induced apoptosis in human epithelioid sarcoma cell lines is enhanced by upregulation of CD95 ligand (FasL/Apo-1L)
    • S. Heikaus, K.S. Matuszek, C.V. Suschek, U. Ramp, P. Reinecke, and E. Grinstein et al. Paclitaxel (Taxol)-induced apoptosis in human epithelioid sarcoma cell lines is enhanced by upregulation of CD95 ligand (FasL/Apo-1L) J Cancer Res Clin Oncol 134 6 2008 689 695
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.6 , pp. 689-695
    • Heikaus, S.1    Matuszek, K.S.2    Suschek, C.V.3    Ramp, U.4    Reinecke, P.5    Grinstein, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.