Slc26a3 deficiency is associated with loss of colonic HCO3- secretion, absence of a firm mucus layer and barrier impairment in mice

Acta Physiologica

Volumn 211, Issue 1, 2014, Pages 161-175

  Xiao, F ^a,b   Yu, Q ^a,b   Li, J ^a,b   Johansson, M E V ^c   Singh, A K ^a   Xia, W ^a,d   Riederer, B ^a   Engelhardt, R ^a   Montrose, M ^e   Soleimani, M ^e   Tian, D A ^b   Xu, G ^b   Hansson, G C ^c   Seidler, U ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d ZHEJIANG UNIVERSITY   (China)

^e UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Anion exchanger; Bicarbonate; Chloride losing diarrhoea; Intestinal barrier; Mucin; Sodium hydrogen exchanger

Indexed keywords

BICARBONATE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEXTRAN SULFATE; FORSKOLIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MESSENGER RNA; MUCIN 2; SODIUM; SODIUM PROTON EXCHANGE PROTEIN 3; ANTIPORTER; SLC26A3 PROTEIN, MOUSE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3;

ALKALINITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GAS ANALYSIS; BLOOD PH; CELL PH; COLON MUCOSA; COLONIC SECRETION; CONTROLLED STUDY; DESCENDING COLON; DEXTRAN SODIUM SULFATE-INDUCED COLITIS; DISEASE ASSOCIATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTESTINE ABSORPTION; INTESTINE CELL; INTESTINE MUCOSA PERMEABILITY; METABOLIC ALKALOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SECRETION RATE; SLC26A3 DEFICIENCY; ACIDOSIS; ANIMAL; COLON; GENETICS; INTESTINE MUCOSA; ION TRANSPORT; KNOCKOUT MOUSE; MALE; METABOLISM; PHYSIOLOGY;

ACIDOSIS; ANIMALS; ANTIPORTERS; BICARBONATES; COLON; INTESTINAL MUCOSA; ION TRANSPORT; MALE; MICE; MICE, KNOCKOUT; MUCIN-2; SODIUM-HYDROGEN ANTIPORTER;

EID: 84899115786     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12220     Document Type: Article

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