Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenum

Gastroenterology

Volumn 122, Issue 3, 2002, Pages 709-724

  Jacob, Petra ^a   Rossmann, Heidi ^a   Lamprecht, Georg ^a   Kretz, Alexandra ^a   Neff, Christina ^a   LinWu, Elena ^a   Gregor, Michael ^a   Groneberg, David A ^b   Kere, Juha ^c   Seidler, Ursula ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; BICARBONATE; CHLORIDE ION; MESSENGER RNA; PROTEIN; PROTEIN DRA; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANION EXCHANGE; ANION TRANSPORT; APICAL MEMBRANE; ARTICLE; BRUSH BORDER; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; DUODENUM; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TRANSPORT; QUANTITATIVE ASSAY; RABBIT; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 0036179392     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2002.31875     Document Type: Article

References (38)

1. Gastroduodenal HCO3(-) transport: Characteristics and proposed role in acidity regulation and mucosal protection
2. 3 cotransport
3. - secretion: Proposed mechanism and comparison with other secretagogues
4. - secretion
5. cDNA cloning and localization of a band 3-related protein from ileum
6. Immunolocalization of anion exchanger AE2 and cation exchanger NHE-1 in distinct adjacent cells of gastric mucosa
7. Different regulation by pHi and osmolarity of the rabbit ileum brush-border and parietal cell basolateral anion exchanger
8. Expression of AE2 anion exchanger in mouse intestine
9. Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas
10. Mutations of the down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea
11. + exchanger
12. - transporter defective in congenital chloride diarrhea
13. The down regulated in adenoma (dra) gene encodes an intestine-specific membrane sulfate transport protein
14. + exchanger NHE1, and carbonic anhydrase in rabbit duodenal bicarbonate secretion
15. A functional CFTR protein is required for mouse intestinal cAMP-, cGMP- and Ca(2+)-dependent HCO3-secretion
16. Intracellular pH-regulating ion transport mechanisms in parietal cell basolateral membrane vesicles
17. - cotransport and expression of NBC1 and NBC2 in rabbit gastric parietal and mucous cells
18. Immunoaffinity purification
19. Intestinal and renal Na+/glucose cotransporters share common structures
20. Localization of the peptide transporter PEPT2 in the lung: Implications for pulmonary oligopeptide uptake
21. pH dependence of Cl/HCO3 exchanger in the rat jejunal enterocyte
22. A sensitive technique for the determination of anion exchange activities in brush-border membrane vesicles. Evidence for two exchangers with different affinities for HCO3- and SITS in rat intestinal epithelium
23. Cl-HCO3 exchange and anion conductance in rat duodenal apical membrane vesicles
24. Kinetics of the chloride-anion exchanger of brush-border membrane vesicles isolated from chicken jejunum
25. Mechanisms of Na+ transport in human distal colonic apical membrane vesicles
26. Contribution of Cl(-)-OH-exchange to electroneutral NaCl absorption in rat distal colon
27. Sodium and chloride transport across rabbit ileal brush border. II. Evidence for Cl-HCO3 exchange and mechanism of coupling
28. - transport in human proximal colonic apical membrane vesicles
29. Immunolocalization of AE2 anion exchanger in rat kidney
30. Immunolocalization and tissue-specific splicing of AE2 anion exchanger in mouse kidney
31. Polarized distribution of key membrane transport proteins in the rat submandibular gland
32. The fodrin-ankyrin cytoskeleton of choroid plexus preferentially colocalizes with apical Na+K(+) Na+ K(+)-ATPase rather than with basolateral anion exchanger AE2
33. - anion exchangers in human liver
34. In birds, NHE2 is major brush-border Na+/H+ exchanger in colon and is increased by a low-NaCl diet
35. NHE2 and NHE3 are human and rabbit intestinal brush-border proteins
36. Quantitative contribution of NHE2 and NHE3 to rabbit ileal brush-border Na+/H+ exchange