Epigenetic silencing of RASSF10 promotes tumor growth in esophageal squamous cell carcinoma

Discovery Medicine

Volumn 17, Issue 94, 2014, Pages

  Lu, Di ^a   Ma, Jun ^a   Guo, Mingzhou ^b,c  

^a ZHENGZHOU UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METHYLATION; RASSF10 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; SQUAMOUS CELL CARCINOMA; TRANSIENT TRANSFECTION; TUMOR GROWTH; CELL DIVISION; ESOPHAGUS TUMOR; GENETIC EPIGENESIS; GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

PRIMER DNA; RASSF10 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL LINE, TUMOR; DNA PRIMERS; EPIGENESIS, GENETIC; ESOPHAGEAL NEOPLASMS; GENE SILENCING; HUMANS; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84899107840     PISSN: 15396509     EISSN: 19447930     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Alaoui SS, Dessirier V, de Araujo E, Alexaki V-I, Pelekanou V, Lkhider M, Stathopoulos EN, Castanas E, Bagot M, Bensussan A, Tsapis A. TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus. PLoS One 7(3):e33609, 2012.
2. Andolfi G, Fousteri G, Rossetti M, Magnani CF, Jofra T, Locafaro G, Bondanza A, Gregori S, Roncarolo M-G. Enforced IL-10 expression confers Type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells. Mol Ther 20(9):1778-1790, 2012.
3. Dallol A, Agathanggelou A, Fenton SL, Ahmed-Choudhury J, Hesson L, Vos MD, Clark GJ, Downward J, Maher ER, Latif F. RASSFIA interacts with microtubule-associated proteins and modulates microtubule dynamics. Cancer Res 64(12):4112-4116, 2004.
4. Dansranjavin T, Wagenlehner F, Gattenloehner S, Steger K, Weidner W, Dammann R, Schagdarsurengin U. Epigenetic down regulation of RASSF10 and its possible clinical implication in prostate carcinoma. Prostate 72(14):1550-1558, 2012.
5. Dong Y, Ji G, Shi J-R, Cao A-L, Xie J-Q, Wu D-Z. Arrest of human gastric cancer AGS cells by tangeretin via CyclinB1 upregulation and inhibition of ERK phosphorylation. Zhongguo Yaolixue Tongbao 28(6):823-827, 2012.
6. Dunwell TL, Hesson LB, Catchpoole D, Maher ER, Latif F. The novel RASSF6 and RASSF10 candidate tumor suppressor genes are frequently epigenetically inactivated in childhood leukemias. Proceedings of the American Association for Cancer Research Annual Meeting 50:120-120, 2009.
7. Fernandes MS, Carneiro F, Oliveira C, Seruca R. Colorectal cancer and RASSF family uA special emphasis on RASSF1A. Int J Cancer 132(2):251-258, 2013.
8. Guo M, Ren J, Brock MV, Herman JG, Carraway HE. Promoter methylation of HIN-1 in the progression to esophageal squamous cancer. Epigenetics 3(6):336-341, 2008.
9. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 93(18):9821-9826, 1996.
10. Hill VK, Underhill-Day N, Krex D, Robel K, Sangan CB, Summersgill HR, Morris M, Gentle D, Chalmers AD, Maher ER, Latif F. Epigenetic inactivation of the RASSF10 candidate tumor suppressor gene is a frequent and an early event in gliomagenesis. Oncogene 30(8):978-989, 2011.
11. Kong KL, Kwong DL, Fu L, Chan THM, Chen L, Liu H, Li Y, Zhu Y-H, Bi J, Qin Y-R. Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. Cancer Res 70(21):8832-8841, 2010.
12. Langford-Smith A, Wilkinson FL, Langford-Smith KJ, Holley RJ, Sergijenko A, Howe SJ, Bennett WR, Jones SA, Wraith JE, Merry CL, Wynn RF, Bigger BW. Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice. Mol Ther 20(8):1610-1621, 2012.
13. Li JY, Epidemiology of esophageal cancer in China. National Cancer Institute Monograph 62:113-120, 1982.
14. Li X, Liu W, Cheung K-F, Chu ESH, Tao Q, Sung JJ, Yu J. Epigenetic characterization of RAS association domain-containing protein 10 as a functional tumor suppressor in gastric cancer. Gastroenterology 140(5):S144-S145, 2011.
15. Liu J-S, Wang Q, Zhang J-B, Kong L-J, Yao S-Y, Zheng D-Y, Xu Q-Y. Construction and functional activity of a recombinant vector expressing rat glutamic acid decarboxylase 65. Neurosci Bull 27(6):430-435, 2011.
16. Liu X, Wang J, Sun B, Zhang Y, Zhu J, Li C. Cell growth inhibition, G(2)M cell cycle arrest, and apoptosis induced by the novel compound Alternol in human gastric carcinoma cell line MGC803. Invest New Drugs 25(6):505-517, 2007.
17. Pisani P, Parkin DM, Ferlay J. Estimates of the worldwide mortality from eighteen major cancers in 1985. Implications for prevention and projections of future burden. Int J Cancer 55(6):891-903, 1993.
18. Richter AM, Pfeifer GP, Dammann RH. The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta 1796(2):114-128, 2009.
19. Schagdarsurengin U, Richter AM, Woehler C, Dammann RH. Frequent epigenetic inactivation of RASSF10 in thyroid cancer. Epigenetics 4(8):571-576, 2009.
20. Sherwood V, Recino A, Jeffries A, Ward A, Chalmers AD. The N-terminal RASSF family, a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation. Biochem J 425:303-311, 2010.
21. Underhill-Day N, Hill V, Latif F. N-terminal RASSF family (RASSF7-RASSF10): A mini review. Epigenetics 6(3):284-292, 2011.
22. Yin D, Jia Y, Yu Y, Brock MV, Herman JG, Han C, Su X, Liu Y, Guo M. SOX17 methylation inhibits its antagonism of Wnt signaling pathway in lung cancer. Discov Med 74:33-40, 2012.
23. Yu Y, Yin D, Hoque MO, Cao B, Jia Y, Yang Y, Guo M. AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer. Tumor Biol 33(2):307-314, 2012.
24. Zhang F, Yao Y, Zhou R, Su K, Citra F, Wang D-A. Optimal construction and delivery of dual-functioning lentiviral vectors for type I collagen-suppressed chondrogenesis in synovium-derived mesenchymal stem cells. Pharm Res 28(6):1338-1348, 2011.
25. Zhao J, Wu G, Bu F, Lu B, Liang A, Cao L, Tong X, Lu X, Wu M, Guo Y. Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region-containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma. Hepatology 51(1):142-153, 2010.