Smac mimetic compound LCL161 sensitizes esophageal carcinoma cells to radiotherapy by inhibiting the expression of inhibitor of apoptosis protein

Tumor Biology

Volumn 35, Issue 3, 2014, Pages 2565-2574

  Qin, Qin ^a   Zuo, Yun ^b   Yang, Xi ^a   Lu, Jing ^a   Zhan, Liangliang ^a   Xu, Liping ^a   Zhang, Chi ^a   Zhu, Hongcheng ^a   Liu, Jia ^a   Liu, Zheming ^a   Tao, Guangzhou ^c   Dai, Shengbin ^d   Zhang, Xizhi ^e   Ma, Jianxin ^f   Cai, Jing ^g   Sun, Xinchen ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b Suzhou Medical College of Soochow University   (China)

^c THE AFFILIATED HUAIAN NO 1 PEOPLE S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^d People's Hospital of Taizhou   (China)

^e NORTHERN JIANGSU PEOPLE S HOSPITAL   (China)

^f Department of Radiation Oncology No2 People's Hospital of Lian Yungang   (China)

^g Nantong Tumor Hospital   (China)

Author keywords

Apoptosis; ESCC; IAP; LCL161; Radiosensitization

Indexed keywords

CASPASE 8; CASPASE INHIBITOR; INHIBITOR OF APOPTOSIS PROTEIN 1; LCL 161; PEPTIDOMIMETIC AGENT; RADIOSENSITIZING AGENT; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL PROLIFERATION; CELL SURVIVAL; CLONOGENIC ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MTT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIZATION;

APOPTOSIS; BIOMIMETICS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESOPHAGEAL NEOPLASMS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIAL PROTEINS; RADIATION-SENSITIZING AGENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIAZOLES;

EID: 84899107750     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1338-2     Document Type: Article

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