Impaired epicardial activation-repolarization coupling contributes to the proarrhythmic effects of hypokalaemia and dofetilide in guinea pig ventricles

Acta Physiologica

Volumn 211, Issue 1, 2014, Pages 48-60

  Osadchii, O E ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AALBORG UNIVERSITY   (Denmark)

Author keywords

Activation repolarization coupling; Cardiac dysrhythmia; Dofetilide; Hypokalaemia

Indexed keywords

DELAYED RECTIFIER POTASSIUM CHANNEL; DOFETILIDE; PHENETHYLAMINE DERIVATIVE; POTASSIUM CHANNEL BLOCKING AGENT; SULFONAMIDE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTRODE; ELECTROPHYSIOLOGICAL PROCEDURES; EPICARDIUM; EXCITATION; EXTRASYSTOLE; FEMALE; GUINEA PIG; HEART ARRHYTHMIA; HEART LEFT VENTRICLE; HEART PACING; HEART PREEXCITATION; HEART RIGHT VENTRICLE; HYPOKALEMIA; NONHUMAN; PRIORITY JOURNAL; REPOLARIZATION; TACHYCARDIA; ANIMAL; ARRHYTHMIAS, CARDIAC; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; ELECTROCARDIOGRAPHY; HEART CONTRACTION; HEART MUSCLE CONDUCTION SYSTEM; HEART VENTRICLE; PATHOPHYSIOLOGY; PHYSIOLOGY; REFRACTORY PERIOD;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; ELECTROCARDIOGRAPHY; FEMALE; GUINEA PIGS; HEART CONDUCTION SYSTEM; HEART VENTRICLES; HYPOKALEMIA; MYOCARDIAL CONTRACTION; PHENETHYLAMINES; POTASSIUM CHANNEL BLOCKERS; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; SULFONAMIDES;

EID: 84899100586     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12259     Document Type: Article

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