Ultrafast sodium channel block by dietary fish oil prevents dofetilide-induced ventricular arrhythmias in rabbit hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 4, 2008, Pages

  Dujardin, K S ^a   Dumotier, B ^c   David, M ^d   Guizy, M ^d   Valenzuela, C ^d   Hondeghem, L M ^b,e  

^a Regionaal Ziekenhuis Heilig Hart Tienen   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c NOVARTIS PHARMA AG   (Switzerland)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^e Hondeghem Pharmaceutical Consulting   (Belgium)

Author keywords

Antiarrhythmia agents; Ion channels; Omega 3 fatty acids; Torsades de pointes

Indexed keywords

DOCOSAHEXAENOIC ACID; DOFETILIDE; EDIBLE OIL; FISH OIL; ICOSAPENTAENOIC ACID ETHYL ESTER; OMEGA 3 FATTY ACID;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ARTICLE; CLINICAL STUDY; CONTROL GROUP; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART INFARCTION; HEART REPOLARIZATION; HEART VENTRICLE ARRHYTHMIA; HUMAN; HUMAN CELL; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; RABBIT; SUDDEN DEATH; TORSADE DES POINTES; TREATMENT DURATION; TRIANGULATION;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; DIET; DISEASE MODELS, ANIMAL; DOCOSAHEXAENOIC ACIDS; FEMALE; HEART CONDUCTION SYSTEM; KINETICS; PERFUSION; PHENETHYLAMINES; RABBITS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SULFONAMIDES; TORSADES DE POINTES;

EID: 57049187833     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01219.2007     Document Type: Article

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